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Cleft palate and minor metabolic disturbances in a mouse global Arl15 gene knockout Bai, Ying; Bentley, Liz; Ma, Chao; Naveenan, Navaratnam; Cleak, James; Wu, Yixing; Simon, Michelle M.; Westerberg, Henrik; Canas, Ramon Casero; Horner, Neil; Pandey, Rajesh; Paphiti, Keanu; Schulze, Ulrike; Mianne, Joffrey; Hough, Tertius; Teboul, Lydia; de Baaij, Jeroen H. F.; Cox, Roger D. Share Save
Cysteine-lowering treatment with mesna against obesity: Proof of concept and results from a human phase I, dose-finding study Vinknes, Kathrine J.; Olsen, Thomas; Zare, Hasse Khiabani; Bastani, Nasser E.; Stolt, Emma; Dahl, Anja F.; Cox, Roger D.; Refsum, Helga; Retterstol, Kjetil; Asberg, Anders; Elshorbagy, Amany Share Save
A Mouse Model with a Frameshift Mutation in the Nuclear Factor I/X (NFIX) Gene Has Phenotypic Features of Marshall-Smith Syndrome Kooblall, Kreepa G.; Stevenson, Mark; Stewart, Michelle; Harris, Lachlan; Zalucki, Oressia; Dewhurst, Hannah; Butterfield, Natalie; Leng, Houfu; Hough, Tertius A.; Ma, Da; Siow, Bernard; Potter, Paul; Cox, Roger D.; Brown, Stephen D. M.; Horwood, Nicole; Wright, Benjamin; Lockstone, Helen; Buck, David; Vincent, Tonia L.; Hannan, Fadil M.; Bassett, J. H. Duncan; Williams, Graham R.; Lines, Kate E.; Piper, Michael; Wells, Sara; Teboul, Lydia; Hennekam, Raoul C.; Thakker, Rajesh V. Share Save
A Wars2 mutant mouse shows a sex and diet specific change in fat distribution, reduced food intake and depot-specific upregulation of WAT browning Muso, Milan; Bentley, Liz; Vizor, Lucie; Yon, Marianne; Burling, Keith; Barker, Peter; Zolkiewski, Louisa A. K.; Cox, Roger D.; Dumbell, Rebecca Share Save
Linking the FTO obesity rs1421085 variant circuitry to cellular, metabolic, and organismal phenotypes in vivo Laber, Samantha; Forcisi, Sara; Bentley, Liz; Petzold, Julia; Moritz, Franco; Smirnov, Kirill S.; Al Sadat, Loubna; Williamson, Iain; Strobel, Sophie; Agnew, Thomas; Sengupta, Shahana; Nicol, Tom; Grallert, Harald; Heier, Margit; Honecker, Julius; Mianne, Joffrey; Teboul, Lydia; Dumbell, Rebecca; Long, Helen; Simon, Michelle; Lindgren, Cecilia; Bickmore, Wendy A.; Hauner, Hans; Schmitt-Kopplin, Philippe; Claussnitzer, Melina; Cox, Roger D. Share Save
A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density Sinnott-Armstrong, Nasa; Sousa, Isabel S.; Laber, Samantha; Rendina-Ruedy, Elizabeth; Dankel, Simon E. Nitter; Ferreira, Teresa; Mellgren, Gunnar; Karasik, David; Rivas, Manuel; Pritchard, Jonathan; Guntur, Anyonya R.; Cox, Roger D.; Lindgren, Cecilia M.; Hauner, Hans; Sallari, Richard; Rosen, Clifford J.; Hsu, Yi-Hsiang; Lander, Eric S.; Kiel, Douglas P.; Claussnitzer, Melina Share Save
The KCNJ11-E23K Gene Variant Hastens Diabetes Progression by Impairing Glucose-Induced Insulin Secretion Sachse, Gregor; Haythorne, Elizabeth; Hill, Thomas; Proks, Peter; Joynson, Russell; Terron-Exposito, Raul; Bentley, Liz; Tucker, Stephen J.; Cox, Roger D.; Ashcroft, Frances M. Share Save
Maternal and offspring high-fat diet leads to platelet hyperactivation in male mice offspring Gaspar, Renato S.; Unsworth, Amanda J.; Al-Dibouni, Alaa; Bye, Alexander P.; Sage, Tanya; Stewart, Michelle; Wells, Sara; Cox, Roger D.; Gibbins, Jonathan M.; Sellayah, Dyan; Hughes, Craig E. Share Save
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Mylk3 null C57BL/6N mice develop cardiomyopathy, whereas Nnt null C57BL/6J mice do not Williams, Jack L.; Paudyal, Anju; Awad, Sherine; Nicholson, James; Grzesik, Dominika; Botta, Joaquin; Meimaridou, Eirini; Maharaj, Avinaash, V; Stewart, Michelle; Tinker, Andrew; Cox, Roger D.; Metherell, Lou A. Share Save
Reduction of fibrillar strain-rate sensitivity in steroid-induced osteoporosis linked to changes in mineralized fibrillar nanostructure Xi, L.; De Falco, P.; Barbieri, E.; Karunaratne, A.; Bentley, L.; Esapa, C. T.; Davis, G. R.; Terrill, N. J.; Cox, R. D.; Pugno, N. M.; Thakker, R. V.; Weinkamer, R.; Wu, W. W.; Fang, D. N.; Gupta, H. S. Share Save
The development of a high throughput drug-responsive model of white adipose tissue comprising adipogenic 3T3-L1 cells in a 3D matrix Graham, Alexander D.; Pandey, Rajesh; Tsancheva, Viktoriya S.; Candeo, Alessia; Botchway, Stanley W.; Allan, Alasdair J.; Teboul, Lydia; Madi, Kamel; Babra, Tahkur S.; Zolkiewski, Louisa A. K.; Xue, Xuan; Bentley, Liz; Gannon, Joan; olof, Sam N.; Cox, Roger D. Share Save
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Abcc5 Knockout Mice Have Lower Fat Mass and Increased Levels of Circulating GLP-1 Cyranka, Malgorzata; Veprik, Anna; McKay, Eleanor J.; van Loon, Nienke; Thijsse, Amber; Cotter, Luke; Hare, Nisha; Saibudeen, Affan; Lingam, Swathi; Pires, Elisabete; Larraufie, Pierre; Reimann, Frank; Gribble, Fiona; Stewart, Michelle; Bentley, Elizabeth; Lear, Pamela; McCullagh, James; Cantley, James; Cox, Roger D.; de Wet, Heidi Share Save
Mice with a Brd4 Mutation Represent a New Model of Nephrocalcinosis Gorvin, Caroline M.; Loh, Nellie Y.; Stechman, Michael J.; Falcone, Sara; Hannan, Fadil M.; Ahmad, Bushra N.; Piret, Sian E.; Reed, Anita A. C.; Jeyabalan, Jeshmi; Leo, Paul; Marshall, Mhairi; Sethi, Siddharth; Bass, Paul; Roberts, Ian; Sanderson, Jeremy; Wells, Sara; Hough, Tertius A.; Bentley, Liz; Christie, Paul T.; Simon, Michelle M.; Mallon, Ann-Marie; Schulz, Herbert; Cox, Roger D.; Brown, Matthew A.; Huebner, Norbert; Brown, Steve D.; Thakker, Rajesh V. Share Save
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