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Xikun Han

Harvard T.H. Chan School of Public Health

34H-index
115Paper Count
3.8KCitation Count
Published Papers 45
Publication Date
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Circulating metabolites, genetics and lifestyle factors in relation to future risk of type 2 diabetes
errNature Medicine
IF50
err2026-01-14
err0
errOAAI
errJun Li; Jie Hu; Huan Yun; Zhendong Mei; Xingyan Wang; Kai Luo; Marta Guasch-Ferré; Xikun Han; Buu Truong; Jordi Merino; Chengyong Jia; Miguel Ruiz-Canela; Casey M. Rebholz; Eun Hye Moon; Taryn Alkis; Guning Liu; Jie Yao; Xiyuan Zhang; Bianca C. Porneala; Jordi Salas-Salvadó; Thomas J. Wang; Josée Dupuis; Elizabeth Selvin; Xiuqing Guo; Shilpa N. Bhupathiraju; Jennifer A. Brody; Yongmei Liu; Alexis C. Wood; Kari E. North; Su Yon Jung; Ching-Ti Liu; Nona Sotoodehnia; Simin Liu; Lesley F. Tinker; A. Heather Eliassen; JoAnn E. Manson; Jose C. Florez; Robert E. Gerszten; Clary B. Clish; Liming Liang; Rozenn N. Lemaitre; Katherine L. Tucker; Stephen S. Rich; Jerome I. Rotter; Miguel Angel Martínez-González; Kathryn M. Rexrode; James B. Meigs; Eric Boerwinkle; Robert C. Kaplan; Frank B. Hu; Bing Yu; Qibin Qi
errShare
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Single-cell multiregion epigenomic rewiring in Alzheimer’s disease progression and cognitive resilience
errCell
IF42.5
err2025-08-01
err0
errOAAI
errZunpeng Liu; Shanshan Zhang; Benjamin T. James; Kyriaki Galani; Riley J. Mangan; Stuart Benjamin Fass; Chuqian Liang; Manoj M. Wagle; Carles A. Boix; Yosuke Tanigawa; Sukwon Yun; Yena Sung; Xushen Xiong; Na Sun; Lei Hou; Martin Wohlwend; Mufan Qiu; Xikun Han; Lei Xiong; Efthalia Preka; Lei Huang; William F. Li; Li-Lun Ho; Amy Grayson; Julio Mantero; Alexey Kozlenkov; Hansruedi Mathys; Tianlong Chen; Stella Dracheva; David A. Bennett; Li-Huei Tsai; Manolis Kellis
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Reply
errOphthalmology Science
IF4.6
err2025-04-05
err0
errOAAI
errAbadh K. Chaurasia; Connor J. Greatbatch; Xikun Han; Puya Gharahkhani; David A. Mackey; Stuart MacGregor; Jamie E. Craig; Alex W. Hewitt
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errSave
SINGLE-CELL MULTI-COHORT TRANSCRIPTOMIC DISSECTION OF BIPOLAR DISORDER
errEUROPEAN NEUROPSYCHOPHARMACOLOGY
IF6.7
err2024-10-01
err0
PREAI
errHan, Xikun; Mohammadi, Shahin; Fullard, John F.; Subburaju, Sivan; Tso, Daniel R.; Hourihan, Makayla; Sun, Na; Hou, Lei; Hoffman, Gabriel E.; Bendl, Jaroslav; Lee, Donghoon; Roussos, Panos; Kellis, Manolis; Ruzicka, W. Brad
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Highly Accurate and Precise Automated Cup-to-Disc Ratio Quanti fi cation for Glaucoma Screening
errOPHTHALMOLOGY SCIENCE
IF4.6
err2024-09-01
err1
errOAAI
errChaurasia, Abadh K.; Greatbatch, Connor J.; Han, Xikun; Gharahkhani, Puya; Mackey, David A.; MacGregor, Stuart; Craig, Jamie E.; Hewitt, Alex W.
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errSave
Crosstalk between epitranscriptomic and epigenomic modifications and its implication in human diseases
errCELL GENOMICS
IF9
err2024-08-01
err1
errOAAI
errLi, Chengyu; Chen, Kexuan; Fang, Qianchen; Shi, Shaohui; Nan, Jiuhong; He, Jialin; Yin, Yafei; Li, Xiaoyu; Li, Jingyun; Hou, Lei; Hu, Xinyang; Kellis, Manolis; Han, Xikun; Xiong, Xushen
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Deep Learning-Based Identification of Intraocular Pressure-Associated Genes Influencing Trabecular Meshwork Cell Morphology
errOPHTHALMOLOGY SCIENCE
IF4.6
err2024-07-01
err5
errOAAI
errGreatbatch, Connor J.; Lu, Qinyi; Hung, Sandy; Tran, Son N.; Wing, Kristof; Liang, Helena; Han, Xikun; Zhou, Tiger; Siggs, Owen M.; Mackey, David A.; Liu, Guei-Sheung; Cook, Anthony L.; Powell, Joseph E.; Craig, Jamie E.; Macgregor, Stuart; Hewitt, Alex W.
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errSave
High throughput functional profiling of genes at intraocular pressure loci reveals distinct networks for glaucoma
errHUMAN MOLECULAR GENETICS
IF3.2
err2024-01-25
err4
errOAAI
errGreatbatch, Connor J.; Lu, Qinyi; Hung, Sandy; Barnett, Alexander J.; Wing, Kristof; Liang, Helena; Han, Xikun; Zhou, Tiger; Siggs, Owen M.; Mackey, David A.; Cook, Anthony L.; Senabouth, Anne; Liu, Guei-Sheung; Craig, Jamie E.; Macgregor, Stuart; Powell, Joseph E.; Hewitt, Alex W.
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errSave
Plasma Metabolites Associated with OCT Features of Age-Related Macular Degeneration
errOPHTHALMOLOGY SCIENCE
IF4.6
err2024-01-01
err4
errOAAI
errLains, Ines; Han, Xikun; Gil, Joao; Providencia, Joana; Nigalye, Archana; Alvarez, Rodrigo; Douglas, Vivian Paraskevi; Mendez, Kevin; Katz, Raviv; Tsougranis, Gregory; Li, Jinglun; Kelly, Rachel S.; Kim, Ivana K.; Lasky-Su, Jessica; Silva, Rufino; Miller, Joan W.; Liang, Liming; Vavvas, Demetrios; Miller, John B.; Husain, Deeba
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errSave
Genome-Wide Meta-analysis Identifies Risk Loci and Improves Disease Prediction of Age-Related Macular Degeneration
errOPHTHALMOLOGY
IF9.5
err2024-01-01
err12
errOAAI
errHe, Weixiong; Han, Xikun; Ong, Jue-Sheng; Wu, Yeda; Hewitt, Alex W.; Mackey, David A.; Gharahkhani, Puya; Macgregor, Stuart
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errSave
Uncovering the complex relationship between balding, testosterone and skin cancers in men
errNATURE COMMUNICATIONS
IF15.7
err2023-10-03
err4
errOAAI
errOng, Jue-Sheng; Seviiri, Mathias; Dusingize, Jean Claude; Wu, Yeda; Han, Xikun; Shi, Jianxin; Olsen, Catherine M.; Neale, Rachel E.; Thompson, John F.; Saw, Robyn P. M.; Shannon, Kerwin F.; Mann, Graham J.; Martin, Nicholas G.; Medland, Sarah E.; Gordon, Scott D.; Scolyer, Richard A.; Long, Georgina V.; Iles, Mark M.; Landi, Maria Teresa; Whiteman, David C.; Macgregor, Stuart; Law, Matthew H.
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Diagnosis of Early Bacterial Pneumonia and Sepsis After Cardiovascular Surgery: A Diagnostic Prediction Model Based on LASSO Logistic Regression
errinflammation research
IF4.1
err2023-09-01
err1
errOAAI
errZhang, Hai-Tao; Wang, Kuo; Li, Ze-Shi; Wang, Chuang-Shi; Han, Xi-Kun; Chen, Wei; Fan, Fu-Dong; Pan, Jun; Zhou, Qing; Cao, Hai-Long; Pan, Hao-Dong; Hafu, Xiateke; Li, Chen; Fan, Guo-Liang; Pan, Tuo; Wang, Dong-Jin; Wang, Wei
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errSave
High Polygenic Risk Is Associated with Earlier Initiation and Escalation of Treatment in Early Primary Open-Angle Glaucoma
errOPHTHALMOLOGY
IF9.5
err2023-08-01
err7
PREAI
errMarshall, Henry N.; Mullany, Sean; Han, Xikun; Qassim, Ayub; He, Weixiong; Hassall, Mark M.; Schmidt, Joshua; Thomson, Daniel; Nguyen, Thi Thi; Berry, Ella C.; Knight, Lachlan S. W.; Hollitt, Georgina L.; Ridge, Bronwyn; Schulz, Angela; Mills, Richard A.; Healey, Paul R.; Agar, Ashish; Galanopoulos, Anna; Landers, John; Graham, Stuart L.; Hewitt, Alex W.; Casson, Robert J.; MacGregor, Stuart; Siggs, Owen M.; Craig, Jamie E.
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errSave
Integrating genetics and metabolomics from multi- ethnic and multi-fluid data reveals putative mechanisms for age-related macular degeneration
errCELL REPORTS MEDICINE
IF10.6
err2023-07-01
err14
errOAAI
errHan, Xikun; Lains, Ines; Li, Jun; Li, Jinglun; Chen, Yiheng; Yu, Bing; Qi, Qibin; Boerwinkle, Eric; Kaplan, Robert; Thyagarajan, Bharat; Daviglus, Martha; Joslin, Charlotte E.; Cai, Jianwen; Guasch-Ferre, Marta; Tobias, Deirdre K.; Rimm, Eric; Ascherio, Alberto; Costenbader, Karen; Karlson, Elizabeth; Mucci, Lorelei; Eliassen, A. Heather; Zeleznik, Oana; Miller, John; Vavvas, Demetrios G.; Kim, Ivana K.; Silva, Rufino; Miller, Joan; Hu, Frank; Willett, Walter; Lasky-Su, Jessica; Kraft, Peter; Richards, J. Brent; MacGregor, Stuart; Husain, Deeba; Liang, Liming
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errSave
Large-scale multitrait genome-wide association analyses identify hundreds of glaucoma risk loci
errNATURE GENETICS
IF31.8
err2023-06-29
err34
errOAAI
errHan, Xikun; Gharahkhani, Puya; Hamel, Andrew R.; Ong, Jue Sheng; Renteria, Miguel E.; Mehta, Puja; Dong, Xianjun; Pasutto, Francesca; Hammond, Christopher; Young, Terri L.; Hysi, Pirro; Lotery, Andrew J.; Jorgenson, Eric; Choquet, Helene; Hauser, Michael; Bailey, Jessica Cooke N.; Nakazawa, Toru; Akiyama, Masato; Shiga, Yukihiro; Fuller, Zachary L.; Wang, Xin; Hewitt, Alex W.; Craig, Jamie E.; Pasquale, Louis R.; Mackey, David A.; Wiggs, Janey L.; Khawaja, Anthony P.; Segre, Ayellet, V; MacGregor, Stuart
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errSave
The low-dose colchicine in patients after non-CABG cardiac surgery: a randomized controlled trial
errCRITICAL CARE
IF9.3
err2023-02-07
err12
errOAAI
errPan, Tuo; Jiang, Chen-Yu; Zhang, He; Han, Xi-Kun; Zhang, Hai-Tao; Jiang, Xin-Yi; Chen, Wei; Wang, Kuo; Fan, Fu-Dong; Pan, Jun; Zhou, Qing; Wang, Chuang-Shi; Zhang, Li; Wang, Dong-Jin
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errSave
Discovery of genomic loci associated with sleep apnea risk through multi-trait GWAS analysis with snoring
errSLEEP
IF4.9
err2022-12-16
err17
errOAAI
errCampos, Adrian, I; Ingold, Nathan; Huang, Yunru; Mitchell, Brittany L.; Kho, Pik-Fang; Han, Xikun; Garcia-Marin, Luis M.; Ong, Jue-Sheng; Law, Matthew H.; Yokoyama, Jennifer S.; Martin, Nicholas G.; Dong, Xianjun; Cuellar-Partida, Gabriel; MacGregor, Stuart; Aslibekyan, Stella; Renteria, Miguel E.
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Novel plasma and brain proteins that are implicated in multiple sclerosis
errBRAIN
IF11.7
err2022-11-08
err5
PREAI
errLin, Xin; Yang, Yuanhao; Gresle, Melissa; Cuellar-Partida, Gabriel; Han, Xikun; Stankovich, Jim; Simpson-Yap, Steve; Fuh-Ngwa, Valery; Charlesworth, Jac; Burdon, Kathryn P.; Butzkueven, Helmut; Taylor, Bruce, V; Zhou, Yuan
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errSave
Obesity-related biomarkers underlie a shared genetic architecture between childhood body mass index and childhood asthma
errCOMMUNICATIONS BIOLOGY
IF5.1
err2022-10-17
err13
errOAAI
errHan, Xikun; Zhu, Zhaozhong; Xiao, Qian; Li, Jun; Hong, Xiumei; Wang, Xiaobin; Hasegawa, Kohei; Camargo, Carlos A.; Liang, Liming
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Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degeneration
errNATURE COMMUNICATIONS
IF15.7
err2022-07-26
err32
errOAAI
errSenabouth, Anne; Daniszewski, Maciej; Lidgerwood, Grace E.; Liang, Helena H.; Hernandez, Damian; Mirzaei, Mehdi; Keenan, Stacey N.; Zhang, Ran; Han, Xikun; Neavin, Drew; Rooney, Louise; Sanchez, Maria Isabel G. Lopez; Gulluyan, Lerna; Paulo, Joao A.; Clarke, Linda; Kearns, Lisa S.; Gnanasambandapillai, Vikkitharan; Chan, Chia-Ling; Nguyen, Uyen; Steinmann, Angela M.; McCloy, Rachael A.; Farbehi, Nona; Gupta, Vivek K.; Mackey, David A.; Bylsma, Guy; Verma, Nitin; MacGregor, Stuart; Watt, Matthew J.; Guymer, Robyn H.; Powell, Joseph E.; Hewitt, Alex W.; Pebay, Alice
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Research Directions

No research directions
Co-authors
Cooperation Journals
W
Walter C. Willett
H-index: 313 · Papers: 2.7K
J
JoAnn E. Manson
H-index: 255 · Papers: 2.7K
F
Frank B. Hu
H-index: 244 · Papers: 1.9K
C
Cornelia M. van Duijn
H-index: 238 · Papers: 1.9K
N
Nicholas G. Martin
H-index: 221 · Papers: 2.8K
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