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Immunophenotyping schizophrenia subtypes stratified by antipsychotic response Li, Yanhui; Ong, Jocelyn Wen Xin; See, Yuen Mei; Yee, Jie Yin; Tang, Charmaine; Zheng, Shushan; Ng, Boon Tat; Lee, Bernett Teck Kwong; Rotzschke, Olaf; Andiappan, Anand Kumar; Lee, Jimmy Share Save
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Eosinophilic allergic rhinitis is strongly associated with the CD45RBlo subset of CD161+ Th2 cells that secretes IL-2, IL-3, IL-4, IL-5, IL-9, and IL-13 Lee, Wendy W. L.; Puan, Kia Joo; Lee, Bernett; Chua, Celine; Koh, Ser Mei; Yusof, Nurhashikin; Tan, Kim Peng; Luis, Boris San; Ong, Jocelyn; Merid, Simon Kebede; Ang, Rachel; Chan, Xue Ying; Hui, Low Jing; Terenzani, Elisa; Lum, Josephine; Foo, Shihui; Zolezzi, Francesca; Yan, Annabelle Tay Sok; Melen, Erik; Yi, Soh Jian; Rotzschke, Olaf; Andiappan, Anand Kumar Share Save
Soluble Signal Inhibitory Receptor on Leukocytes-1 Is Released from Activated Neutrophils by Proteinase 3 Cleavage von Richthofen, Helen J.; Westerlaken, Geertje H. A.; Gollnast, Doron; Besteman, Sjanna; Delemarre, Eveline M.; Rodenburg, Karlijn; Moerer, Petra; Stapels, Daphne A. C.; Andiappan, Anand K.; Rotzschke, Olaf; Nierkens, Stefan; Leavis, Helen L.; Bont, Louis J.; Rooijakkers, Suzan H. M.; Meyaard, Linde Share Save
Functional CTLA-4 variants associate to both allergic asthma and rhinitis potentially by modulating naive regulatory T cells Andiappan, Anand Kumar; Puan, Kia Joo; Sio, Yang Yie; Ally, Fauziah; Lee, Bernett; Matta, Sri Anusha; Yusof, Nurhashikin; Larbi, Anis; Wang, De Yun; Chew, Fook Tim; Rotzschke, Olaf Share Save
Transcriptomics of rhinovirus persistence reveals sustained expression of RIG-I and interferon-stimulated genes in nasal epithelial cells in vitro Ong, Hsiao Hui; Andiappan, Anand Kumar; Duan, Kaibo; Lum, Josephine; Liu, Jing; Tan, Kai Sen; Howland, Shanshan; Lee, Bernett; Ong, Yew Kwang; Thong, Mark; Chow, Vincent T.; Wang, De-Yun Share Save
Neutrophilic inflammation and epithelial barrier disruption in nasal polyps characterize NSAID-exacerbated respiratory disease Andiappan, Anand Kumar; Asad, Mohammad; Chua, Celine; Sehanobish, Esha; Ren, Zhen; Chan, Xue Ying; Lum, Josephine; Ang, Nicholas; Duan, Kaibo; Gersten, Adam; Abuzeid, Waleed M.; Akbar, Nadeem; Gibber, Marc; Howland, Shanshan; Lee, Bernett; Rotzschke, Olaf; Porcelli, Steven A.; Jerschow, Elina Share Save
Data-Driven Analysis of COVID-19 Reveals Persistent Immune Abnormalities in Convalescent Severe Individuals Lim, Jackwee; Puan, Kia Joo; Wang, Liang Wei; Teng, Karen Wei Weng; Loh, Chiew Yee; Tan, Kim Peng; Carissimo, Guillaume; Chan, Yi-Hao; Poh, Chek Meng; Lee, Cheryl Yi-Pin; Fong, Siew-Wai; Yeo, Nicholas Kim-Wah; Chee, Rhonda Sin-Ling; Amrun, Siti Naqiah; Chang, Zi Wei; Tay, Matthew Zirui; Torres-Ruesta, Anthony; Leo Fernandez, Norman; How, Wilson; Andiappan, Anand Kumar; Lee, Wendy; Duan, Kaibo; Tan, Seow-Yen; Yan, Gabriel; Kalimuddin, Shirin; Lye, David Chien; Leo, Yee-Sin; Ong, Sean W. X.; Young, Barnaby E.; Renia, Laurent; Ng, Lisa F. P.; Lee, Bernett; Rotzschke, Olaf Share Save
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression Vosa, Urmo; Claringbould, Annique; Westra, Harm-Jan; Bonder, Marc Jan; Deelen, Patrick; Zeng, Biao; Kirsten, Holger; Saha, Ashis; Kreuzhuber, Roman; Yazar, Seyhan; Brugge, Harm; Oelen, Roy; de Vries, Dylan H.; van der Wijst, Monique G. P.; Kasela, Silva; Pervjakova, Natalia; Alves, Isabel; Fave, Marie-Julie; Agbessi, Mawusse; Christiansen, Mark W.; Jansen, Rick; Seppala, Ilkka; Tong, Lin; Teumer, Alexander; Schramm, Katharina; Hemani, Gibran; Verlouw, Joost; Yaghootkar, Hanieh; Flitman, Reyhan Sonmez; Brown, Andrew; Kukushkina, Viktorija; Kalnapenkis, Anette; Rueger, Sina; Porcu, Eleonora; Kronberg, Jaanika; Kettunen, Johannes; Lee, Bernett; Zhang, Futao; Qi, Ting; Hernandez, Jose Alquicira; Arindrarto, Wibowo; Beutner, Frank; Dmitrieva, Julia; Elansary, Mahmoud; Fairfax, Benjamin P.; Georges, Michel; Heijmans, Bastiaan T.; Hewitt, Alex W.; Kahonen, Mika; Kim, Yungil; Knight, Julian C.; Kovacs, Peter; Krohn, Knut; Li, Shuang; Loeffler, Markus; Marigorta, Urko M.; Mei, Hailang; Momozawa, Yukihide; Mueller-Nurasyid, Martina; Nauck, Matthias; Nivard, Michel G.; Penninx, Brenda W. J. H.; Pritchard, Jonathan K.; Raitakari, Olli T.; Rotzschke, Olaf; Slagboom, Eline P.; Stehouwer, Coen D. A.; Stumvoll, Michael; Sullivan, Patrick; 't Hoen, Peter A. C.; Thiery, Joachim; Tonjes, Anke; van Dongen, Jenny; van Iterson, Maarten; Veldink, Jan H.; Voelker, Uwe; Warmerdam, Robert; Wijmenga, Cisca; Swertz, Morris; Andiappan, Anand; Montgomery, Grant W.; Ripatti, Samuli; Perola, Markus; Kutalik, Zoltan; Dermitzakis, Emmanouil; Bergmann, Sven; Frayling, Timothy; van Meurs, Joyce; Prokisch, Holger; Ahsan, Habibul; Pierce, Brandon L.; Lehtimaki, Terho; Boomsma, Dorret, I; Psaty, Bruce M.; Gharib, Sina A.; Awadalla, Philip; Milani, Lili; Ouwehand, Willem H.; Downes, Kate; Stegle, Oliver; Battle, Alexis; Visscher, Peter M.; Yang, Jian; Scholz, Markus; Powell, Joseph; Gibson, Greg; Esko, Tonu; Franke, Lude Share Save
FUT6 deficiency compromises basophil function by selectively abrogating their sialyl-Lewis x expression Puan, Kia Joo; Luis, Boris San; Yusof, Nurhashikin; Kumar, Dilip; Andiappan, Anand Kumar; Lee, Wendy; Cajic, Samanta; Vuckovic, Dragana; Chan, Jing De; Dollner, Tobias; Hou, Han Wei; Jiang, Yunxuan; Tian, Chao; Rapp, Erdmann; Poidinger, Michael; Wang, De Yun; Soranzo, Nicole; Lee, Bernett; Rotzschke, Olaf Share Save
Atopic dermatitis microbiomes stratify into ecologic dermotypes enabling microbial virulence and disease severity Tay, Angeline S. L.; Li, Chenhao; Nandi, Tannistha; Chng, Kern Rei; Andiappan, Anand Kumar; Mettu, Vijaya Saradhi; de Cevins, Camille; Ravikrishnan, Aarthi; Dutertre, Charles-Antoine; Wong, X. F. Colin C.; Ng, Amanda Hui Qi; Matta, Sri Anusha; Ginhoux, Florent; Rotzschke, Olaf; Chew, Fook Tim; Tang, Mark B. Y.; Yew, Yik Weng; Nagarajan, Niranjan; Common, John E. A. Share Save
Genome-wide association studies of exacerbations in children using long-acting beta2-agonists Slob, Elise M. A.; Richards, Levi B.; Vijverberg, Susanne J. H.; Longo, Cristina; Koppelman, Gerard H.; Pijnenburg, Marielle W. H.; Bel, Elisabeth H. D.; Neerincx, Anne H.; Luis, Esther Herrera; Perez-Garcia, Javier; Chew, Fook Tim; Sio, Yang Yie; Andiappan, Anand K.; Turner, Steve W.; Mukhopadhyay, Somnath; Palmer, Colin N. A.; Hawcutt, Daniel; Jorgensen, Andrea L.; Burchard, Esteban G.; Hernandez-Pacheco, Natalia; Pino-Yanes, Maria; Maitland-van der Zee, Anke H. Share Save
Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles Gamage, Akshamal M.; Tan, Kai Sen; Chan, Wharton O. Y.; Liu, Jing; Tan, Chee Wah; Ong, Yew Kwang; Thong, Mark; Andiappan, Anand K.; Anderson, Danielle E.; Wang, De Yun; Wang, Lin-Fa Share Save
Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19 Carissimo, Guillaume; Xu, Weili; Kwok, Immanuel; Abdad, Mohammad Yazid; Chan, Yi-Hao; Fong, Siew-Wai; Puan, Kia Joo; Lee, Cheryl Yi-Pin; Yeo, Nicholas Kim-Wah; Amrun, Siti Naqiah; Chee, Rhonda Sin-Ling; How, Wilson; Chan, Stephrene; Fan, Bingwen Eugene; Andiappan, Anand Kumar; Lee, Bernett; Roetzschke, Olaf; Young, Barnaby Edward; Leo, Yee-Sin; Lye, David Chien; Renia, Laurent; Ng, Lai Guan; Larbi, Anis; Ng, Lisa F. P. Share Save
Role of IL-13Ra2 in modulating IL-13 induced MUC5AC and ciliary changes in healthy and CRSwNP mucosa Liu, Jing; Li, Ying Ying; Andiappan, Anand Kumar; Yan, Yan; Tan, Kai Sen; Ong, Hsiao Hui; Thong, Kim Thye; Ong, Yew Kwang; Yu, Feng Gang; Low, Heng Boon; Zhang, Yong Liang; Shi, Li; Wang, De Yun Share Save
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