logo
CanyamAI summaries for academic research
language
MobileMobile
  • Phone FeatureWeChat Mini Program
EnglishEnglish
noticeNotice
BlogBlog
delete
arrow
Back
J

James M. Murphy

The Walter and Eliza Hall Institute of Medical Research

89H-index
484Paper Count
2.6WCitation Count
Published Papers 185
Publication Date
logo
A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease
errScience
IF45.8
err2026-08-27
err0
PREAI
errJiyi Pang; Aysha H. Al-Ani; Komal M. Patel; Yunzhuo Zhou; Samuel N. Young; Jinjin Chen; Isabella Kong; Marilou Barrios; James A. Rickard; Siqi Chen; Xiuquan Ma; Farzaneh Shojaee; Seong-Beom Kim; Siavash Foroughi; Wayne Cawthorne; Annette V. Jacobsen; Asha Jois; Ashley L. Weir; Lachlan W. Whitehead; Pradeep Rajasekhar; Christopher R. Horne; Ruqian Lyu; Lucy J. Mather; Raymond K. H. Yip; Ellen Tsui; Imadh Azeez; Tao Tan; Weiwei Liang; Suresh Sivanesan; Andrew Metz; Ash Patwardhan; Natalie Shea; Guru Iyngkaran; Daniel Schneider; Alexander T. Elford; William Beattie; Finlay Macrae; Gianmaria Liccardi; Henning Walczak; Yuxia Zhang; Oliver M. Sieber; Tim Spelman; Lisa Giulino-Roth; Michael Christie; Yunshun Chen; Kelly L. Rogers; Rory Bowden; Sandra E. Nicholson; Kate E. Lawlor; Edwin D. Hawkins; Britt Christensen; Andre L. Samson; James E. Vince; James M. Murphy
errShare
errSave
Low Agonism and Balanced Pathway Modulation Distinguish an M1 Muscarinic Receptor Positive Allosteric Modulator Lacking Cholinergic Adverse Effects
errACS Chemical Neuroscience
IF3.9
err2026-06-30
err0
PREAI
errHuong T. M. Nguyen; Elham Khajehali; Vi Pham; John W. Scott; Toby A. Dite; Laura F. Dagley; James M. Murphy; Geoff Thompson; Andrew B. Tobin; David M. Thal; Arthur Christopoulos; Emma T. van der Westhuizen; Celine Valant
errShare
errSave
Impact of BECLIN1 haploinsufficiency on goblet cell function and susceptibility to colitis
errCell Death & Disease
IF9.6
err2026-06-17
err0
errOAAI
errJuliani Juliani; Sharon Tran; Tiffany J. Harris; Sarah L. Ellis; Aysha H. Al-Ani; Yashodha Wijebandara; Komal M. Patel; Samuel N. Young; Marco Evangelista; David Baloyan; Camilla M. Reehorst; Rebecca Nightingale; Laura J. Jenkins; Peter De Cruz; Kinga Duszyc; Benjamin T. Kile; Alpha S. Yap; John M. Mariadason; Britt Christensen; André L. Samson; James M. Murphy; Walter D. Fairlie; Erinna F. Lee
errShare
errSave
Inspiring discovery through reviews and visualization in biochemistry
errTrends in Biochemical Sciences
IF11
err2026-04-02
err0
PREAI
errJames M. Murphy; Arthur J. Olson
errShare
errSave
IAP-based biodegraders can convert necroptosis to apoptosis and eliminate cancer driving protein complexes
errCell Chemical Biology
IF7.2
err2026-03-31
err0
errOAAI
errXiuquan Ma; François Vaillant; Deepagan Gopal; Kael Schoffer; Farzaneh Shojaee; Jiyi Pang; Christopher A. Baldwin; James M. Murphy; John Silke; Maria C. Tanzer; Jane E. Visvader; Ranja Salvamoser; James E. Vince
errShare
errSave
Necroptosis in both tumour and stromal compartments determines responsiveness to immunogenic cell death-based immunotherapy
errNature Communications
IF15.7
err2026-03-01
err0
errOAAI
errFernando, Winnie; Clucas, Jarama; Rizzo, Alberto; Singer, Ramsay; Goode, Emily; Tiu, Crescens; Layzell, Scott; Konecnik, Joshua; Wilson, Rebecca; John, Sidonie Wicky; Jouny, Samuel; Guppy, Naomi; Boulat, Victoire; Mannion, Jonathan; Goicoechea, Maria; Tan, Shaun; Lawson, Sam; Starling, Chris; Elshtein, Gabrielle; Ravindran, Nivedita; Montgomery, Anna B.; Andres-Ejarque, Rosa; Allen, Mark; Lumbard, Steven; Wallberg, Fredrik; Betteridge, Kai; Scrimgeour, Ross; Robertson, David; Ward, George; Sims, Martin; Smyth, Tomoko; Samson, Andre L.; Murphy, James M.; Ivankovic, Daniela Kolarevic; Arwert, Esther N.; Calado, Dinis P.; Grigoriadis, Anita; Smalley, Matthew J.; Melcher, Alan; Haider, Syed; Lawrence, Toby; Roxanis, Ioannis; Tutt, Andrew N. J.; Tenev, Tencho; Meier, Pascal
errShare
errSave
The kinase domain of RIPK3 tunes its scaffolding functions
errCell Death and Differentiation
IF15.4
err2026-02-01
err1
PREAI
errChiou, Shene; Horne, Christopher R.; Patel, Komal M.; Preaudet, Adele; Rickard, James A.; Young, Samuel N.; Jois, Asha; Garnish, Sarah E.; Hempel, Anne; Hall, Cathrine; Hildebrand, Joanne M.; Kueh, Andrew J.; Silke, John; Putoczki, Tracy L.; Hawkins, Edwin D.; Samson, Andre L.; Murphy, James M.
errShare
errSave
Unconventional binding of calmodulin to CHK2 kinase inhibits catalytic activity
errBIOCHEMICAL JOURNAL
IF4.3
err2025-12-01
err0
errOAAI
errHorne, Christopher R.; Wang, Tingting; Young, Samuel N.; Dite, Toby A.; Nyvall, Hunter G.; Suresh, Sushant; Davies, Katherine A.; Castro, Abner Gonzalez; Vaibhav, Vineet; Mather, Lucy J.; Dagley, Laura F.; Belousoff, Matthew J.; Manning, Gerard; Means, Anthony R.; Burke, John E.; Petersen, Janni; Scott, John W.; Murphy, James M.
errShare
errSave
Inhibition of RIPK1 or RIPK3 kinase activity post ischemia-reper fusion reduces the development of chronic kidney injury
errBIOCHEMICAL JOURNAL
IF4.3
err2025-01-21
err0
errOAAI
errPefanis, Aspasia; Bongoni, Anjan K.; Mcrae, Jennifer L.; Salvaris, Evelyn J.; Fisicaro, Nella; Murphy, James M.; Ierino, Francesco L.; Cowan, Peter J.
errShare
errSave
MLKL deficiency elevates testosterone production in male mice independently of necroptotic functions
errCELL DEATH & DISEASE
IF9.6
err2024-11-21
err0
errOAAI
errChiou, Shene; Cawthorne, Wayne; Soerianto, Thomas; Hofferek, Vinzenz; Patel, Komal M.; Garnish, Sarah E.; Crutchfield, Emma C. Tovey; Hall, Cathrine; Hildebrand, Joanne M.; McConville, Malcolm J.; Lawlor, Kate E.; Hawkins, Edwin D.; Samson, Andre L.; Murphy, James M.
errShare
errSave
Divergent roles of RIPK3 and MLKL in high-fat diet-induced obesity and MAFLD in mice
errLIFE SCIENCE ALLIANCE
IF2.9
err2024-11-12
err0
errOAAI
errTye, Hazel; Conos, Stephanie A.; Djajawi, Tirta M.; Gottschalk, Timothy A.; Abdoulkader, Nasteho; Kong, Isabella Y.; Kammoun, Helene L.; Narayana, Vinod K.; Kratina, Tobias; Speir, Mary; Emery, Jack; Simpson, Daniel S.; Hall, Cathrine; Vince, Angelina J.; Russo, Sophia; Crawley, Rhiannan; Rashidi, Maryam; Hildebrand, Joanne M.; Murphy, James M.; Whitehead, Lachlan; De Souza, David P.; Masters, Seth L.; Samson, Andre L.; Lalaoui, Najoua; Hawkins, Edwin D.; Murphy, Andrew J.; Vince, James E.; Lawlor, Kate E.
errShare
errSave
Death at a funeral: Activation of the dead enzyme, MLKL, to kill cells by necroptosis
errCURRENT OPINION IN STRUCTURAL BIOLOGY
IF7
err2024-10-01
err1
errOAAI
errDavies, Katherine A.; Czabotar, Peter E.; Murphy, James M.
errShare
errSave
Inhibitors identify an auxiliary role for mTOR signalling in necroptosis execution downstream of MLKL activation
errBIOCHEMICAL JOURNAL
IF4.3
err2024-08-27
err1
errOAAI
errGarnish, Sarah E.; Horne, Christopher R.; Meng, Yanxiang; Young, Samuel N.; Jacobsen, Annette, V; Hildebrand, Joanne M.; Murphy, James M.
errShare
errSave
Molecular dissection of the pseudokinase ZED1 expands effector recognition to the tomato immune receptor ZAR1
errPLANT PHYSIOLOGY
IF6.9
err2024-05-15
err2
errOAAI
errDiplock, Nathan; Baudin, Mael; Xiang, Xincheng (Derek); Liang, Lung-Yu; Dai, Weiwen; Murphy, James M.; Lucet, Isabelle S.; Hassan, Jana A.; Lewis, Jennifer D.
errShare
errSave
An immunohistochemical atlas of necroptotic pathway expression
errEMBO MOLECULAR MEDICINE
IF8.3
err2024-05-15
err6
errOAAI
errChiou, Shene; Al-Ani, Aysha H.; Pan, Yi; Patel, Komal M.; Kong, Isabella Y.; Whitehead, Lachlan W.; Light, Amanda; Young, Samuel N.; Barrios, Marilou; Sargeant, Callum; Rajasekhar, Pradeep; Zhu, Leah; Hempel, Anne; Lin, Ann; Rickard, James A.; Hall, Cathrine; Gangatirkar, Pradnya; Yip, Raymond K. H.; Cawthorne, Wayne; Jacobsen, Annette, V; Horne, Christopher R.; Martin, Katherine R.; Ioannidis, Lisa J.; Hansen, Diana S.; Day, Jessica; Wicks, Ian P.; Law, Charity; Ritchie, Matthew E.; Bowden, Rory; Hildebrand, Joanne M.; O'Reilly, Lorraine A.; Silke, John; Giulino-Roth, Lisa; Tsui, Ellen; Rogers, Kelly L.; Hawkins, Edwin D.; Christensen, Britt; Murphy, James M.; Samson, Andre L.
errShare
errSave
Co-clustering of EphB6 and ephrinB1 in trans restrains cancer cell invasion
errCOMMUNICATIONS BIOLOGY
IF5.1
err2024-04-16
err1
errOAAI
errLiang, Lung-Yu; Geoghegan, Niall D.; Mlodzianoski, Michael; Leis, Andrew; Whitehead, Lachlan W.; Surudoi, Minglyanna G.; Young, Samuel N.; Janes, Peter; Shepherd, Doulin; Ghosal, Debnath; Rogers, Kelly L.; Murphy, James M.; Lucet, Isabelle S.
errShare
errSave
Gasdermin and MLKL necrotic cell death effectors: Signaling and diseases
errIMMUNITY
IF26.3
err2024-03-01
err8
PREAI
errLawlor, Kate E.; Murphy, James M.; Vince, James E.
errShare
errSave
Necroptosis does not drive disease pathogenesis in a mouse infective model of SARS-CoV-2 in vivo
errCELL DEATH & DISEASE
IF9.6
err2024-01-30
err7
errOAAI
errBader, Stefanie M.; Cooney, James P.; Bhandari, Reet; Mackiewicz, Liana; Dayton, Merle; Sheerin, Dylan; Georgy, Smitha Rose; Murphy, James M.; Davidson, Kathryn C.; Allison, Cody C.; Pellegrini, Marc; Doerflinger, Marcel
errShare
errSave
Dynamics of necroptosis in kidney ischemia-reperfusion injury
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2023-11-02
err9
errOAAI
errPefanis, Aspasia; Bongoni, Anjan K.; McRae, Jennifer L.; Salvaris, Evelyn J.; Fisicaro, Nella; Murphy, James M.; Ierino, Francesco L.; Cowan, Peter J.
errShare
errSave
A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation
errNATURE COMMUNICATIONS
IF15.7
err2023-09-28
err6
errOAAI
errGarnish, Sarah E.; Martin, Katherine R.; Kauppi, Maria; Jackson, Victoria E.; Ambrose, Rebecca; Eng, Vik Ven; Chiou, Shene; Meng, Yanxiang; Frank, Daniel; Crutchfield, Emma C. Tovey; Patel, Komal M.; Jacobsen, Annette V.; Atkin-Smith, Georgia K.; Di Rago, Ladina; Doerflinger, Marcel; Horne, Christopher R.; Hall, Cathrine; Young, Samuel N.; Cook, Matthew; Athanasopoulos, Vicki; Vinuesa, Carola G.; Lawlor, Kate E.; Wicks, Ian P.; Ebert, Gregor; Ng, Ashley P.; Slade, Charlotte A.; Pearson, Jaclyn S.; Samson, Andre L.; Silke, John; Murphy, James M.; Hildebrand, Joanne M.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
M
Michael Berk
H-index: 155 · Papers: 2.2K
P
Peter Vandenabeele
H-index: 154 · Papers: 669
G
Gabriel Núñez
H-index: 152 · Papers: 519
J
Josep M. Llovet
H-index: 151 · Papers: 794
R
Robert G. Parton
H-index: 149 · Papers: 705
View more