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Limiting ER-associated degradation capacity triggers acute and chronic effects on insulin biosynthesis Arunagiri, Anoop; Haataja, Leena; Alam, Maroof; Gleason, Noah F.; Mastroianni, Emma; Cheng, Chao-Yin; Bazzi, Sami; Knupp, Jeffrey; Metawea, Ibrahim; Hassan, Anis; Larkin, Dennis; Fang, Deyu; Tsai, Billy; Qi, Ling; Arvan, Peter Share Save
Stimulated thyroid hormone synthesis machinery drives thyrocyte cell death independent of ER stress Young, Crystal; Zhang, Xiaohan; Wang, Xiaofan; Kellogg, Aaron P.; Pena, Kevin; Cumming, August Z.; Liao, Xiao-Hui; Larkin, Dennis; Zhang, Hao; Mastroianni, Emma; Grasberger, Helmut; Refetoff, Samuel; Arvan, Peter Share Save
Recessive TMEM167A variants cause neonatal diabetes, microcephaly, and epilepsy syndrome Virgilio, Enrico; Tielens, Sylvia; Bonfield, Georgia; Nian, Fang-Shin; Sawatani, Toshiaki; Vinci, Chiara; Govier, Molly; Montaser, Hossam; Lartigue, Romane; Arunagiri, Anoop; Liboz, Alexandrine; Da Silva, Flavia Natividade; Lytrivi, Maria; Papadopoulou, Theodora; Wakeling, Matthew N.; Russ-Silsby, James; Bowman, Pamela; Johnson, Matthew B.; Laver, Thomas W.; Piron, Anthony; Yi, Xiaoyan; Fantuzzi, Federica; Hendrickx, Sirine; Igoillo-Esteve, Mariana; Santacreu, Bruno J.; Suntharesan, Jananie; Ghildiyal, Radha; Hegde, Darshan; Shah, Nikhil; Acar, Sezer; Donmez, Beyhan Ozkaya; Ozkan, Behzat; Mohsin, Fauzia; Talaat, Iman M.; Abbas, Mohamed Tarek; Abbas, Omar Tarek; Alghamdi, Hamed Ali; Kandemir, Nurgun; Flanagan, Sarah E.; Scharfmann, Raphael; Arvan, Peter; Raoux, Matthieu; Nguyen, Laurent; Hattersley, Andrew T.; Cnop, Miriam; De Franco, Elisa Share Save
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Small-Molecule FICD Inhibitors Suppress Endogenous and Pathologic FICD-Mediated Protein AMPylation Chatterjee, Bhaskar K.; Alam, Mohammad Maroof; Chakravorty, Arghya; Lacy, Shannon M.; Giblin, William; Rech, Jason; Brooks, Charles L., III; Arvan, Peter; Truttmann, Matthias C. Share Save
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Integrated stress response plasticity governs normal cell adaptation to chronic stress via the PP2A-TFE3-ATF4 pathway Avelar, Rita A.; Gupta, Riya; Carvette, Grace; Leprevost, Felipe da Veiga; Jasti, Medhasri; Colina, Jose; Teitel, Jessica; Nesvizhskii, Alexey I.; O'Connor, Caitlin M.; Hatzoglou, Maria; Shenolikar, Shirish; Arvan, Peter; Narla, Goutham; Difeo, Analisa Share Save
Role of Sec61α2 Translocon in Insulin Biosynthesis Xu, Xiaoxi; Bell, Thomas W.; Le, Truc; Zhao, Ivy; Walker, Emily; Wang, Yiqing; Xu, Ning; Soleimanpour, Scott A.; Russ, Holger A.; Qi, Ling; Tsai, Billy; Liu, Ming; Arvan, Peter Share Save
Untangling the genetics of beta cell dysfunction and death in type 1 diabetes Robertson, Catherine C.; Elgamal, Ruth M.; Henry-Kanarek, Belle A.; Arvan, Peter; Chen, Shuibing; Dhawan, Sangeeta; Eizirik, Decio L.; Kaddis, John S.; Vahedi, Golnaz; Parker, Stephen C. J.; Gaulton, Kyle J.; Soleimanpour, Scott A. Share Save
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Permanent neonatal diabetes-causing insulin mutations have dominant negative effects on beta cell identity Zhang, Yuwei; Sui, Lina; Du, Qian; Haataja, Leena; Yin, Yishu; Viola, Ryan; Xu, Shuangyi; Nielsson, Christian Ulrik; Leibel, Rudolph L.; Barbetti, Fabrizio; Arvan, Peter; Egli, Dieter Share Save
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SERCA2 regulates proinsulin processing and processing enzyme maturation in pancreatic beta cells Iida, Hitoshi; Kono, Tatsuyoshi; Lee, Chih-Chun; Krishnan, Preethi; Arvin, Matthew C.; Weaver, Staci A.; Jarvela, Timothy S.; Branco, Renato C. S.; McLaughlin, Madeline R.; Bone, Robert N.; Tong, Xin; Arvan, Peter; Lindberg, Iris; Evans-Molina, Carmella Share Save
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Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction Yeh, Yu-Te; Sona, Chandan; Yan, Xin; Li, Yunxiao; Pathak, Adrija; McDermott, Mark I.; Xie, Zhigang; Liu, Liangwen; Arunagiri, Anoop; Wang, Yuting; Cazenave-Gassiot, Amaury; Ghosh, Adhideb; von Meyenn, Ferdinand; Kumarasamy, Sivarajan; Najjar, Sonia M.; Jia, Shiqi; Wenk, Markus R.; Traynor-Kaplan, Alexis; Arvan, Peter; Barg, Sebastian; Bankaitis, Vytas A.; Poy, Matthew N. Share Save
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