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The small inhibitor WM-1119 effectively targets KAT6A-rearranged AML, but not KMT2A-rearranged AML, despite shared KAT6 genetic dependency Sheridan, Mathew; Maqbool, Muhammad Ahmad; Largeot, Anne; Clayfield, Liam; Xu, Jingru; Moncaut, Natalia; Sellers, Robert; Whittle, Jessica; Paggetti, Jerome; Iqbal, Mudassar; Aucagne, Romain; Delva, Laurent; Baker, Syed Murtuza; Lie-a-Ling, Michael; Kouskoff, Valerie; Lacaud, Georges Share Save
IκBα controls dormancy in hematopoietic stem cells via retinoic acid during embryonic development Thambyrajah, Roshana; Maqueda, Maria; Fadlullah, Muhammad Zaki; Proffitt, Martin; Neo, Wen Hao; Guillen, Yolanda; Casado-Pelaez, Marta; Herrero-Molinero, Patricia; Brujas, Carla; Castelluccio, Noemi; Gonzalez, Jessica; Iglesias, Arnau; Marruecos, Laura; Ruiz-Herguido, Cristina; Esteller, Manel; Mereu, Elisabetta; Lacaud, Georges; Espinosa, Lluis; Bigas, Anna Share Save
Cis inhibition of NOTCH1 through JAGGED1 sustains embryonic hematopoietic stem cell fate Thambyrajah, Roshana; Maqueda, Maria; Neo, Wen Hao; Imbach, Kathleen; Guillen, Yolanda; Grases, Daniela; Fadlullah, Zaki; Gambera, Stefano; Matteini, Francesca; Wang, Xiaonan; Calero-Nieto, Fernando J.; Esteller, Manel; Florian, Maria Carolina; Porta, Eduard; Benedito, Rui; Gottgens, Berthold; Lacaud, Georges; Espinosa, Lluis; Bigas, Anna Share Save
Autocrine activation of MAPK signaling mediates intrinsic tolerance to androgen deprivation in LY6D cancer cells Steiner, Ivana; Flores-Tellez, Teresita del N. J.; Mevel, Renaud; Ali, Amin; Wang, Pengbo; Schofield, Pieta; Behan, Caron; Forsythe, Nicholas; Ashton, Garry; Taylor, Catherine; Mills, Ian G.; Oliveira, Pedro; McDade, Simon S.; Zaiss, Dietmar M.; Choudhury, Ananya; Lacaud, Georges; Baena, Esther Share Save
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Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors Neo, Wen Hao; Meng, Yiran; Rodriguez-Meira, Alba; Fadlullah, Muhammad Z. H.; Booth, Christopher A. G.; Azzoni, Emanuele; Thongjuea, Supat; de Bruijn, Marella F. T. R.; Jacobsen, Sten Eirik W.; Mead, Adam J.; Lacaud, Georges Share Save
Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia Simeoni, Fabrizio; Romero-Camarero, Isabel; Camera, Francesco; Amaral, Fabio M. R.; Sinclair, Oliver J.; Papachristou, Evangelia K.; Spencer, Gary J.; Lie-A-Ling, Michael; Lacaud, Georges; Wiseman, Daniel H.; Carroll, Jason S.; Somervaille, Tim C. P. Share Save
Reduction of RUNX1 transcription factor activity by a CBFA2T3-mimicking peptide: application to B cell precursor acute lymphoblastic leukemia Jakobczyk, Helene; Debaize, Lydie; Soubise, Benoit; Avner, Stephane; Rouger-Gaudichon, Jeremie; Commet, Severine; Jiang, Yan; Serandour, Aurelien A.; Rio, Anne-Gaelle; Carroll, Jason S.; Wichmann, Christian; Lie-a-Ling, Michael; Lacaud, Georges; Corcos, Laurent; Salbert, Gilles; Galibert, Marie-Dominique; Gandemer, Virginie; Troadec, Marie-Berengere Share Save
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RUNX1 marks a luminal castration-resistant lineage established at the onset of prostate development Mevel, Renaud; Steiner, Ivana; Mason, Susan; Galbraith, Laura C. A.; Patel, Rahima; Fadlullah, Muhammad Z. H.; Ahmad, Imran; Leung, Hing Y.; Oliveira, Pedro; Blyth, Karen; Baena, Esther; Lacaud, Georges Share Save
Alternative Enhancer Usage and Targeted Polycomb Marking Hallmark Promoter Choice during T Cell Differentiation Maqbool, Muhammad Ahmad; Pioger, Leo; El Aabidine, Amal Zine; Karasu, Nezih; Molitor, Anne Marie; Dao, Lan T. M.; Charbonnier, Guillaume; van Laethem, Francois; Fenouil, Romain; Koch, Frederic; Lacaud, Georges; Gut, Ivo; Gut, Marta; Amigorena, Sebastian; Joffre, Olivier; Sexton, Thomas; Spicuglia, Salvatore; Andrau, Jean-Christophe Share Save
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Identification of gene specific cis-regulatory elements during differentiation of mouse embryonic stem cells: An integrative approach using high-throughput datasets Vijayabaskar, M. S.; Goode, Debbie K.; Obier, Nadine; Lichtinger, Monika; Emmett, Amber M. L.; Abidin, Fatin N. Zainul; Shar, Nisar; Hannah, Rebecca; Assi, Salam A.; Lie-A-Ling, Michael; Gottgens, Berthold; Lacaud, Georges; Kouskoff, Valerie; Bonifer, Constanze; Westhead, David R. Share Save
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Runx/Cbfβ complexes protect group 2 innate lymphoid cells from exhausted-like hyporesponsiveness during allergic airway inflammation (vol 10, 447, 2019) Miyamoto, Chizuko; Kojo, Satoshi; Yamashita, Motoi; Moro, Kazuyo; Lacaud, Georges; Shiroguchi, Katsuyuki; Taniuchi, Ichiro; Ebihara, Takashi Share Save
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