Not logged in CLEC12A-directed immunocytokine with target cell-restricted IL-15 activity for treatment of acute myeloid leukemia Klimovich, Boris; Anton, Leonard; Jung, Jinwon; Lim, Yangmi; Lee, Bora; Won, Jonghwa; Zekri, Latifa; Chashchina, Anna; Pfluegler, Martin; Heitmann, Jonas S.; Jung, Gundram; Salih, Helmut R. Share Save
Measurable residual disease monitoring in AML with FLT3-ITD treated with intensive chemotherapy plus midostaurin Ruecker, Frank G.; Bullinger, Lars; Cocciardi, Sibylle; Skambraks, Sabrina; Luck, Tamara J.; Weber, Daniela; Krzykalla, Julia; Pozek, Ema; Schneider, Isabelle; Corbacioglu, Andrea; Gaidzik, Verena I.; Meid, Annika; Aicher, Sophia; Stegelmann, Frank; Schrade, Anika; Theis, Frauke; Fiedler, Walter; Salih, Helmut R.; Wulf, Gerald; Salwender, Hans; Schroeder, Thomas; Goetze, Katharina S.; Kuehn, Michael W. M.; Luebbert, Michael; Schlenk, Richard F.; Benner, Axel; Thol, Felicitas; Heuser, Michael; Ganser, Arnold; Doehner, Hartmut; Doehner, Konstanze Share Save
Warehouse-based, immunopeptidome-guided design of personalised peptide vaccines shows feasibility in clinical trial evaluation in CLL patients Heitmann, Jonas S.; Jung, Susanne; Wacker, Marcel; Maringer, Yacine; Nelde, Annika; Bauer, Jens; Denk, Monika; Hoenisch-Gravel, Naomi; Richter, Marion; Oezbek, Melek T.; Dubbelaar, Marissa L.; Bilich, Tatjana; Pumptow, Marina; Martus, Peter; Illerhaus, Gerald; Denzlinger, Claudio; Steinbach, Francesca; Aulitzky, Walter-Erich; Mueller, Martin R.; Doerfel, Daniela; Rammensee, Hans-Georg; Salih, Helmut R.; Walz, Juliane S. Share Save
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AML-VAC-XS15-01: protocol of a first-in-human clinical trial to evaluate the safety, tolerability and preliminary efficacy of a multi-peptide vaccine based on leukemia stem cell antigens in acute myeloid leukemia patients Jung, Susanne; Nelde, Annika; Maringer, Yacine; Denk, Monika; Zieschang, Lisa; Kammer, Christine; Oezbek, Melek; Martus, Peter; Hackenbruch, Christopher; Englisch, Alexander; Heitmann, Jonas S.; Salih, Helmut R.; Walz, Juliane S. Share Save
Targeting CD276 for T cell-based immunotherapy of breast cancer Hagelstein, Ilona; Wessling, Laura; Rochwarger, Alexander; Zekri, Latifa; Klimovich, Boris; Tegeler, Christian M.; Jung, Gundram; Schuerch, Christian M.; Salih, Helmut R.; Lutz, Martina S. Share Save
Phase I trial of a personalized multi-peptide vaccine combined with the TLR1/2 ligand XS15 under Bruton-Tyrosine-Kinase inhibitor (BTKi) treatment in chronic lymphocytic leukemia (CLL) patients Hackenbruch, C.; Heitmann, J. S.; Jung, S.; Maringer, Y.; Wacker, M.; Nelde, A.; Marconato, M.; Zieschang, L.; Kammer, C.; Ozbek, M. T.; Richter, M.; Denk, M.; Salih, H. R.; Walz, J. S. Share Save
iVAC-XS15-CLL01: personalized multi-peptide vaccination in combination with the TLR1/2 ligand XS15 in CLL patients undergoing BTK-inhibitor-based regimens Englisch, Alexander; Hayn, Clara; Jung, Susanne; Heitmann, Jonas S.; Hackenbruch, Christopher; Maringer, Yacine; Nelde, Annika; Wacker, Marcel; Denk, Monika; Zieschang, Lisa; Kammer, Christine; Martus, Peter; Salih, Helmut R.; Walz, Juliane S. Share Save
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Induction of NK cell reactivity against acute myeloid leukemia by Fc-optimized CD276 (B7-H3) antibody Stefanczyk, Sylwia A.; Hagelstein, Ilona; Lutz, Martina S.; Mueller, Stefanie; Holzmayer, Samuel J.; Jarjour, Grace; Zekri, Latifa; Heitmann, Jonas S.; Salih, Helmut R.; Maerklin, Melanie Share Save
FusionVAC22_01: a phase I clinical trial evaluating a DNAJB1-PRKACA fusion transcript-based peptide vaccine combined with immune checkpoint inhibition for fibrolamellar hepatocellular carcinoma and other tumor entities carrying the oncogenic driver fusion Hackenbruch, Christopher; Bauer, Jens; Heitmann, Jonas S.; Maringer, Yacine; Nelde, Annika; Denk, Monika; Zieschang, Lisa; Kammer, Christine; Federmann, Birgit; Jung, Susanne; Martus, Peter; Malek, Nisar P.; Nikolaou, Konstantin; Salih, Helmut R.; Bitzer, Michael; Walz, Juliane S. Share Save
Immunocytokines with target cell-restricted IL-15 activity for treatment of B cell malignancies Zekri, Latifa; Hagelstein, Ilona; Maerklin, Melanie; Klimovich, Boris; Christie, Mary; Lindner, Cornelia; Kaemereit, Sofie; Prakash, Nisha; Mueller, Stefanie; Stotz, Sophie; Maurer, Andreas; Greve, Carsten; Schmied, Bastian; Atar, Daniel; Rammensee, Hans-Georg; Jung, Gundram; Salih, Helmut R. Share Save
Protocol of a first-in-human clinical trial to evaluate the safety, tolerability, and preliminary efficacy of the bispecific CD276xCD3 antibody CC-3 in patients with colorectal cancer (CoRe_CC-3) Jung, Susanne; Schlenk, Richard F.; Hackenbruch, Christopher; Pinzon, Sandra S. L. Roldan; Bitzer, Michael; Pfluegler, Martin; Walz, Juliane S.; Jung, Gundram; Heitmann, Jonas S.; Salih, Helmut R. Share Save
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TOFIMS mass spectrometry-based immunopeptidomics refines tumor antigen identification Gravel, Naomi Hoenisch; Nelde, Annika; Bauer, Jens; Muehlenbruch, Lena; Schroeder, Sarah M.; Neidert, Marian C.; Scheid, Jonas; Lemke, Steffen; Dubbelaar, Marissa L.; Wacker, Marcel; Dengler, Anna; Klein, Reinhild; Mauz, Paul-Stefan; Loewenheim, Hubert; Hauri-Hohl, Mathias; Martin, Roland; Hennenlotter, Joerg; Stenzl, Arnulf; Heitmann, Jonas S.; Salih, Helmut R.; Rammensee, Hans-Georg; Walz, Juliane S. Share Save
Immune Surveillance of Acute Myeloid Leukemia Is Mediated by HLA-Presented Antigens on Leukemia Progenitor Cells Nelde, Annika; Schuster, Heiko; Heitmann, Jonas S.; Bauer, Jens; Maringer, Yacine; Zwick, Melissa; Volkmer, Jens-Peter; Chen, James Y.; Stanger, Anna M. Paczulla; Lehmann, Ariane; Appiah, Bismark; Maerklin, Melanie; Rucker-Braun, Elke; Salih, Helmut R.; Roerden, Malte; Schroeder, Sarah M.; Haering, Max-Felix; Schlosser, Andreas; Schetelig, Johannes; Schmitz, Marc; Boerries, Melanie; Koehler, Natalie; Lengerke, Claudia; Majeti, Ravindra; Weissman, Irving L.; Rammensee, Hans-Georg; Walz, Juliane S. Share Save
Randomized phase-III study of low-dose cytarabine and etoposide? plus ?/- all-trans retinoic acid in older unfit patients with NPM1-mutated acute myeloid leukemia Schlenk, R. F.; Weber, D.; Krzykalla, J.; Kindler, T.; Wulf, G.; Hertenstein, B.; Salih, H. R.; Suedhoff, T.; Krauter, J.; Martens, U.; Wessendorf, S.; Runde, V.; Tischler, H. J.; Bentz, M.; Koller, E.; Heuser, M.; Thol, F.; Benner, A.; Ganser, A.; Doehner, K.; Doehner, H. Share Save
Phase I/II trial of a peptide-based COVID-19 T-cell activator in patients with B-cell deficiency Heitmann, Jonas. S. S.; Tandler, Claudia; Marconato, Maddalena; Nelde, Annika; Habibzada, Timorshah; Rittig, Susanne. M. M.; Tegeler, Christian. M. M.; Maringer, Yacine; Jaeger, Simon. U. U.; Denk, Monika; Richter, Marion; Oezbek, Melek. T. T.; Wiesmueller, Karl-Heinz; Bauer, Jens; Rieth, Jonas; Wacker, Marcel; Schroeder, Sarah. M. M.; Hoenisch Gravel, Naomi; Scheid, Jonas; Maerklin, Melanie; Henrich, Annika; Klimovich, Boris; Clar, Kim L.; Lutz, Martina; Holzmayer, Samuel; Hoerber, Sebastian; Peter, Andreas; Meisner, Christoph; Fischer, Imma; Loeffler, Markus W.; Peuker, Caroline Anna; Habringer, Stefan; Goetze, Thorsten O.; Jaeger, Elke; Rammensee, Hans-Georg; Salih, Helmut R.; Walz, Juliane S. Share Save
Phase I study evaluating the Fc-optimized FLT3 antibody FLYSYN in AML patients with measurable residual disease Heitmann, Jonas S.; Schlenk, Richard F.; Doerfel, Daniela; Kayser, Sabine; Doehner, Konstanze; Heuser, Michael; Thol, Felicitas; Kapp-Schwoerer, Silke; Labrenz, Jannik; Edelmann, Dominic; Maerklin, Melanie; Vogel, Wichard; Bethge, Wolfgang; Walz, Juliane S.; Grosse-Hovest, Ludger; Steiner, Martin; Jung, Gundram; Salih, Helmut R. Share Save
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