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D

Dietmar Rudolf Thal

ku leuven

83H-index
430Paper Count
3.7WCitation Count
Published Papers 185
Publication Date
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Human microglial transitions at the Aβ–tau inflection point associate with divergent pathways to dementia and resilience
errNature Medicine
IF50
err2026-06-04
err0
errOAAI
errAshley Lu; Wei-Ting Chen; Maria Dalby; Diego Sainz Garcia; Marisa Vanheusden; Luuk E. de Vries; Veerle van Lieshout; Araks Martirosyan; Katleen Craessaerts; Sebastiaan Moonen; Magdalena Zielonka; Iordana Chrysidou; Anke Misbaer; Leen Wolfs; Benjamin Pavie; Dick Swaab; Dietmar Rudolf Thal; Inge Huitinga; Annemieke Rozemuller; Susan Karijn Rohde; Marc Hulsman; Henne Holstege; Rita Balice-Gordon; Niels Plath; Mark Fiers; Bart De Strooper
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Alzheimer’s disease subtyping approaches and the role of co-pathologies
errBrain
IF11.7
err2026-05-04
err0
PREAI
errKlara Gawor; Kevin Statz; Jolien Schaeverbeke; Dietmar Rudolf Thal
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Multi-modal dissection of cell-type specific TDP-43 pathology in the motor cortex
errNature Communications
IF15.7
err2026-03-09
err0
errOAAI
errWolfgang P. Ruf; Julia K. Kühlwein; Laura Meier; Sarah J. Brockmann; Jaehyun LeeBae; Ghazaleh Sadri-Vakili; Deniz Yilmazer-Hanke; Susanne Petri; Dietmar R. Thal; Veselin Grozdanov; Karin M. Danzer
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Conformation-specific monoclonal antibodies reveal early Tau structural intermediates in Alzheimer’s disease
errJournal of Biological Chemistry
IF3.9
err2026-02-03
err0
errOAAI
errGrigoria Tsaka; Aida Montserrat Pagès; Cristiano Brás De Sousa; Jeroen Lammertyn; Grzegorz Walkiewicz; Luis Aragão Gomes; Maya Imbrechts; Sophie Tops; Rajasekhar Kolla; Kevin Muwonge; Rik Vandenberghe; Karen Vanhoorelbeke; Christine A.F. von Arnim; Nick Geukens; Frederic Rousseau; Joost Schymkowitz; Dragana Spasic; Dietmar Rudolf Thal; Debby Thomas; Joris Winderickx
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Networks of age-related pathologies and APOE ε4: their role in hippocampal degeneration
errAlzheimer's & Dementia
IF0
err2025-12-24
err0
errOAAI
errKlara Gawor; Sam Verrept; Geethika Arekatla; David Wouters; Alicja Ronisz; Celeste Laureyssen; Helena Ver Donck; Bas Lahaije; Simona Ospitalieri; Mathieu Vandenbulcke; Markus Otto; Christine A.F. von Arnim; Estifanos Ghebremedhin; Rik Vandenberghe; Alejandro Sifrim; Kristel Sleegers; Dietmar Rudolf Thal; Sandra O. Tomé
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RapTB: a lung-derived hemoglobin fragment with activity against Mycobacterium tuberculosis
errFrontiers in Microbiology
IF4.5
err2025-10-24
err0
errOAAI
errLeonard Klevesath; Reiner Noschka; Thomas Vomhof; Jacky Mohnani; Mark Grieshober; Jens Michaelis; Paul Walther; Armando Rodriguez; Nico Preising; Clarissa Read; Sebastian Wiese; Ludger Ständker; Dietmar R. Thal; Jan Münch; Steffen Stenger
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errSave
C9orf72 hexanucleotide repeat expansions impair microglial response in ALS
errNature Neuroscience
IF20
err2025-10-14
err0
errOAAI
errPegah Masrori; Baukje Bijnens; Laura Fumagalli; Kristofer Davie; Suresh Kumar Poovathingal; Tim Meese; Annet Storm; Nicole Hersmus; Raheem Fazal; Diede van den Biggelaar; Bob Asselbergh; Roxane Gruel; Johanna Van Den Daele; Heidi Denton; Paula Polanco Miquel; Simona Manzella; Winnok H. De Vos; Siddhartan Chandran; Ludo Van Den Bosch; Dietmar Rudolf Thal; Renzo Mancuso; Philip Van Damme
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errSave
Differences and overlaps in TDP-43 pathology of ‘pure’ LATE-NC compared to LATE-NC coexisting with Alzheimer’s disease
errActa Neuropathologica
IF9.3
err2025-09-15
err0
PREAI
errSandra O. Tomé; Klara Gawor; Simona Ospitalieri; Alicja Ronisz; Markus Otto; Christine A. F. von Arnim; Estifanos Ghebremedhin; Celeste Laureyssen; Kristel Sleegers; Rik Vandenberghe; Peter T. Nelson; Dietmar Rudolf Thal
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errSave
Tracing neuropathological signatures: TARDBP and C9orf72 double mutations in a Sicilian family
errHUMAN MOLECULAR GENETICS
IF3.2
err2025-09-01
err0
errOAAI
errMasrori, Pegah; Tome, Sandra O.; Dedeene, Lieselot; Remiche, Gauthier; Van Esch, Hilde; Thal, Dietmar Rudolf; Van Damme, Philip
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errSave
The olfactory epithelium: a critical gateway for pathological tau propagation and a target for mitigating tauopathy in the central nervous system
errActa Neuropathologica
IF9.3
err2025-06-19
err0
errOAAI
errMarion Dourte; Esther Paître; Mongia Bouchoucha; Emilien Boyer; Sandra O. Tomé; Emilie Doeraene; Caroline Huart; Karelle Leroy; Dietmar Rudolf Thal; Anabelle Decottignies; Bernard Hanseeuw; Nuria Suelves; Pascal Kienlen-Campard
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Alzheimer's disease neuropathology and its estimation with fluid and imaging biomarkers
errMOLECULAR NEURODEGENERATION
IF17.5
err2025-03-14
err1
errOAAI
errThal, DR; Poesen, K; Vandenberghe, R; De Meyer, S
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Recent Advances in Mass Spectrometry Histochemistry Analysis of FFPE Biobanked Tissues-Close to the Holy Grail in Histopathology?
errLABORATORY INVESTIGATION
IF4.2
err2025-03-01
err0
PREAI
errVerhaert, Peter; Frache, Gilles; Verhaert, Marthe; Thal, Dietmar; Sciot, Raf
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errSave
Autopsy-proven patient with corticobasal degeneration presenting with visuo-constructive disorders as initial symptoms: How advanced MRI sequences can help clinical practice
errJOURNAL OF ALZHEIMERS DISEASE
IF3.1
err2025-02-17
err0
PREAI
errSalman, Yasmine; Huyghe, Lara; Quenon, Lisa; Ghysens, Olivia; Malotaux, Vincent; Tome, Sandra O.; Thal, Dietmar Rudolf; Hanseeuw, Bernard J.
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errSave
α-Synuclein fibrils enhance HIV-1 infection of human T cells, macrophages and microglia
errNATURE COMMUNICATIONS
IF15.7
err2025-01-18
err1
errOAAI
errOlari, Lia-Raluca; Liu, Sichen; Arnold, Franziska; Kuehlwein, Julia; Miro, Marta Gil; Updahaya, Ajeet Rijal; Stuerzel, Christina; Thal, Dietmar Rudolf; Walther, Paul; Sparrer, Konstantin M. J.; Danzer, Karin M.; Muench, Jan; Kirchhoff, Frank
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errSave
Pyroptosis in Alzheimer's disease: cell type-specific activation in microglia, astrocytes and neurons (Vol 145, pg 175, 2023)
errACTA NEUROPATHOLOGICA
IF9.3
err2024-12-23
err0
PREAI
errMoonen, Sebastiaan; Koper, Marta J.; Van Schoor, Evelien; Schaeverbeke, Jolien M.; Vandenberghe, Rik; von Arnim, Christine A. F.; Tousseyn, Thomas; De Strooper, Bart; Thal, Dietmar Rudolf
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errSave
C21ORF2 mutations point towards primary cilia dysfunction in amyotrophic lateral sclerosis
errBRAIN
IF11.7
err2024-12-20
err0
PREAI
errDe Decker, Mathias; Zelina, Pavol; Moens, Thomas G.; Beckers, Jimmy; Contardo, Matilde; Dittlau, Katarina Stoklund; Van Schoor, Evelien; Ronisz, Alicja; Eggermont, Kristel; Moisse, Matthieu; Chandran, Siddharthan; Veldink, Jan H.; Thal, Dietmar Rudolf; van den Bosch, Ludo; Pasterkamp, R. Jeroen; Van Damme, Philip
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pTau pathology in the retina of TAU58 mice: association with ganglion cell degeneration and implications on seeding and propagation of pTau from human brain lysates
errACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
err2024-12-20
err0
errOAAI
errWalkiewicz, Grzegorz; Ronisz, Alicja; Ospitalieri, Simona; Tsaka, Grigoria; Tome, Sandra O.; Vandenberghe, Rik; von Arnim, Christine A. F.; Rousseau, Frederic; Schymkowitz, Joost; De Groef, Lies; Thal, Dietmar Rudolf
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errSave
Amygdala-predominant α-synuclein pathology is associated with exacerbated hippocampal neuron loss in Alzheimer's disease
errBRAIN COMMUNICATIONS
IF4.5
err2024-12-05
err0
errOAAI
errGawor, Klara; Tome, Sandra O.; Vandenberghe, Rik; Van Damme, Philip; Vandenbulcke, Mathieu; Otto, Markus; von Arnim, Christine A. F.; Ghebremedhin, Estifanos; Ronisz, Alicja; Ospitalieri, Simona; Blaschko, Matthew; Thal, Dietmar Rudolf
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Pure LATE-NC: Frequency, clinical impact, and the importance of considering APOE genotype when assessing this and other subtypes of non-Alzheimer's pathologies
errACTA NEUROPATHOLOGICA
IF9.3
err2024-11-15
err0
errOAAI
errKatsumata, Yuriko; Wu, Xian; Aung, Khine Zin; Fardo, David W.; Woodworth, Davis C.; Sajjadi, S. Ahmad; Tome, Sandra O.; Thal, Dietmar Rudolf; Troncoso, Juan C.; Chang, Koping; Mock, Charles; Nelson, Peter T.
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errSave
Inhibition of an Alzheimer's disease-associated form of necroptosis rescues neuronal death in mouse models
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2024-10-30
err1
PREAI
errKoper, Marta J.; Moonen, Sebastiaan; Ronisz, Alicja; Ospitalieri, Simona; Callaerts-Vegh, Zsuzsanna; T'Syen, Dries; Rabe, Sabine; Staufenbiel, Matthias; De Strooper, Bart; Balusu, Sriram; Thal, Dietmar Rudolf
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Research Directions

No research directions
Co-authors
Cooperation Journals
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J
John C. Morris
H-index: 212 · Papers: 2.4K
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Eliezer Masliah
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