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Luis Miguel García‐Segura

Instituto Cajal

98H-index
645Paper Count
3.2WCitation Count
Published Papers 182
Publication Date
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Sex-specific gonadal status determines prefrontal cortex proteome response to tibolone
errBiomedicine & Pharmacotherapy
IF7.5
err2025-08-07
err0
PREAI
errAndrew J. McGovern; Maria Angeles Arevalo; Sergio Ciordia; Luis Miguel Garcia-Segura; George E. Barreto
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Role of Serum Brain-Derived Neurotrophic Factor as a Biomarker of Chronic Pain in Older Adults
errEUROPEAN JOURNAL OF PAIN
IF3.4
err2025-05-01
err0
errOAAI
errOrtola, R.; Sotos-Prieto, M.; Carballo, A.; Cabello-Plan, S.; Koni, Aida; Mustieles, V.; Garcia-Segura, L. M.; Artalejo, A. R.; Rodriguez-Artalejo, F.; Garcia-Esquinas, E.
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Aging is associated with sex-specific alteration in the expression of genes encoding for neuroestradiol synthesis and signaling proteins in the mouse trigeminal somatosensory input
errGEROSCIENCE
IF5.4
err2024-07-02
err1
errOAAI
errBautista-Abad, Alvaro; Garcia-Magro, Nuria; Pinto-Benito, Daniel; Caceres-Pajuelo, Julio Eduardo; Alises, Carlos Vicente; Ganchala, Danny; Lagunas, Natalia; Negredo, Pilar; Garcia-Segura, Luis Miguel; Arevalo, Maria-Angeles; Grassi, Daniela
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Neuroestradiol and neuronal development: Not an exclusive male tale anymore
errFRONTIERS IN NEUROENDOCRINOLOGY
IF6.7
err2023-10-01
err1
errOAAI
errGarcia-Segura, Luis M.; Mendez, Pablo; Arevalo, M. Angeles; Azcoitia, Inigo
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Interaction of gonadal hormones, dopaminergic system, and epigenetic regulation in the generation of sex differences in substance use disorders: A systematic review
errFRONTIERS IN NEUROENDOCRINOLOGY
IF6.7
err2023-10-01
err7
errOAAI
errSantos-Toscano, Raquel; Arevalo, Maria Angeles; Garcia-Segura, Luis Miguel; Grassi, Daniela; Lagunas, Natalia
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The hypothalamic paraventricular nucleus as a central hub for the estrogenic modulation of neuroendocrine function and behavior
errFRONTIERS IN NEUROENDOCRINOLOGY
IF6.7
err2022-04-01
err11
PREAI
errGrassi, D.; Marraudino, M.; Garcia-Segura, L. M.; Panzica, G. C.
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errSave
Tibolone restrains neuroinflammation in mouse experimental autoimmune encephalomyelitis
errJOURNAL OF NEUROENDOCRINOLOGY
IF4.1
err2021-12-27
err6
PREAI
errMancino, Dalila N. J.; Lima, Analia; Roig, Paulina; Garcia Segura, Luis M.; De Nicola, Alejandro F.; Garay, Laura, I
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High-fat diet alters stress behavior, inflammatory parameters and gut microbiota in Tg APP mice in a sex-specific manner
errNEUROBIOLOGY OF DISEASE
IF5.6
err2021-11-01
err27
errOAAI
errYanguas-Casas, Natalia; Torres, Cristina; Crespo-Castrillo, Andrea; Diaz-Pacheco, Sonia; Healy, Kiera; Stanton, Catherine; Chowen, Julie A.; Garcia-Segura, Luis M.; Angeles Arevalo, Maria; Cryan, John F.; de Ceballos, Maria L.
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X-linked histone H3K27 demethylase Kdm6a regulates sexually dimorphic differentiation of hypothalamic neurons
errCELLULAR AND MOLECULAR LIFE SCIENCES
IF6.2
err2021-10-11
err11
errOAAI
errCabrera Zapata, Lucas E.; Cisternas, Carla D.; Sosa, Camila; Garcia-Segura, Luis Miguel; Arevalo, Maria Angeles; Cambiasso, Maria Julia
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Role of Neuroglobin in the Neuroprotective Actions of Estradiol and Estrogenic Compounds
errCELLS
IF5.2
err2021-07-27
err20
errOAAI
errBarreto, George E.; McGovern, Andrew J.; Garcia-Segura, Luis M.
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Role of glial cells in the generation of sex differences in neurodegenerative diseases and brain aging
errMECHANISMS OF AGEING AND DEVELOPMENT
IF5.1
err2021-06-01
err52
errOAAI
errChowen, Julie A.; Garcia-Segura, Luis M.
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Amyloid-β1-40 differentially stimulates proliferation, activation of oxidative stress and inflammatory responses in male and female hippocampal astrocyte cultures
errMECHANISMS OF AGEING AND DEVELOPMENT
IF5.1
err2021-04-01
err12
errOAAI
errLennol, Matthew P.; Canelles, Sandra; Guerra-Cantera, Santiago; Argente, Jesus; Miguel Garcia-Segura, Luis; de Ceballos, Maria L.; Chowen, Julie A.; Frago, Laura M.
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Tibolone as Hormonal Therapy and Neuroprotective Agent
errTRENDS IN ENDOCRINOLOGY AND METABOLISM
IF12.6
err2020-10-01
err23
PREAI
errPablo Del Rio, Juan; Molina, Santiago; Hidalgo-Lanussa, Oscar; Miguel Garcia-Segura, Luis; Barreto, George E.
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errSave
G Protein-Coupled Estrogen Receptor Immunoreactivity Fluctuates During the Estrous Cycle and Show Sex Differences in the Amygdala and Dorsal Hippocampus
errFRONTIERS IN ENDOCRINOLOGY
IF4.6
err2020-08-07
err25
errOAAI
errLlorente, Ricardo; Marraudino, Marilena; Carrillo, Beatriz; Bonaldo, Brigitta; Simon-Areces, Julia; Abellanas-Perez, Pedro; Rivero-Aguilar, Marina; Fernandez-Garcia, Jose M.; Pinos, Helena; Garcia-Segura, Luis M.; Collado, Paloma; Grassi, Daniela
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errSave
Aging and sex: Impact on microglia phagocytosis
errAGING CELL
IF7.1
err2020-07-29
err57
errOAAI
errYanguas-Casas, Natalia; Crespo-Castrillo, Andrea; Arevalo, Maria-Angeles; Garcia-Segura, Luis Miguel
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G Protein-Coupled Estrogen Receptor Immunoreactivity in the Rat Hypothalamus Is Widely Distributed in Neurons, Astrocytes, and Oligodendrocytes, Fluctuates during the Estrous Cycle, and Is Sexually Dimorphic
errNEUROENDOCRINOLOGY
IF2.8
err2020-06-22
err26
errOAAI
errMarraudino, Marilena; Carrillo, Beatriz; Bonaldo, Brigitta; Llorente, Ricardo; Campioli, Elia; Garate, Iciar; Pinos, Helena; Garcia-Segura, Luis Miguel; Collado, Paloma; Grassi, Daniela
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Estradiol-dependent axogenesis and Ngn3 expression are determined by XY sex chromosome complement in hypothalamic neurons
errSCIENTIFIC REPORTS
IF3.9
err2020-05-19
err8
errOAAI
errDaniela Cisternas, Carla; Cabrera Zapata, Lucas Ezequiel; Rafael Mir, Franco; Julia Scerbo, Maria; Angeles Arevalo, Maria; Miguel Garcia-Segura, Luis; Julia Cambiasso, Maria
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Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites
errFRONTIERS IN NEUROENDOCRINOLOGY
IF6.7
err2020-04-01
err24
errOAAI
errGiatti, Silvia; Diviccaro, Silvia; Falvo, Eva; Miguel Garcia-Segura, Luis; Melcangi, Roberto Cosimo
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The synthetic steroid tibolone exerts sex-specific regulation of astrocyte phagocytosis under basal conditions and after an inflammatory challenge
errJOURNAL OF NEUROINFLAMMATION
IF10.1
err2020-01-28
err23
errOAAI
errCrespo-Castrillo, Andrea; Garcia-Segura, Luis-Miguel; Arevalo, Maria-Angeles
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Sex differences in steroid levels and steroidogenesis in the nervous system: Physiopathological role
errFRONTIERS IN NEUROENDOCRINOLOGY
IF6.7
err2020-01-01
err44
errOAAI
errGiatti, Silvia; Diviccaro, Silvia; Serafini, Melania Maria; Caruso, Donatella; Miguel Garcia-Segura, Luis; Viviani, Barbara; Melcangi, Roberto C.
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Research Directions

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Co-authors
Cooperation Journals
A
Amirhossein Sahebkar
H-index: 174 · Papers: 2.4K
J
John F. Cryan
H-index: 162 · Papers: 1.3K
C
Catherine Stanton
H-index: 135 · Papers: 839
T
Tamás L. Horváth
H-index: 114 · Papers: 483
M
Matthias H. Tschöp
H-index: 112 · Papers: 621
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