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S

Sebastian Uhrig

german cancer research center

27H-index
116Paper Count
3.0KCitation Count
Published Papers 49
Publication Date
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The molecular heterogeneity and clinical impact of genomic driver alterations in prostate cancer
errNature Communications
IF15.7
err2026-10-16
err0
errOAAI
errDiogo Pellegrina; Daria Kiriy; Kevin C. L. Cheng; Francesco Favero; Enrichetta Miletti; Zoe P. Klein; Barbara Hernando; Andre V. Olsen; Atef Sahli; Yunfan Fu; Pavlo Lutsik; Weerachai Jaratlerdsiri; William J. Hutchison; G. Steven Bova; Daniel S. Brewer; Mark Brook; Benedikt Brors; Adam Butler; Géraldine Cancel-Tassin; Niall M. Corcoran; Olivier Cussenot; Abraham Gihawi; Etsehiwot G. Girma; Vincent J. Gnanapragasam; Anis A. Hamid; Housheng Hansen He; Eddie Luidy L. Imada; G. Maria Jakobsdottir; Chol-hee Jung; Francesca Khani; Zsofia Kote-Jarai; Philippe Lamy; Gregory Leeman; Massimo Loda; Ramyar Molania; Lucio R. Queiroz; Tobias Rausch; Brian Robinson; Karina D. Sørensen; Sebastian Uhrig; Yaobo Xu; Takafumi N. Yamaguchi; Claudio Zanettini; Stefano Mangiola; Lena Voith von Voithenberg; Luigi Marchionni; Anthony T. Papenfuss; Bernard Pope; Vanessa M. Hayes; Thorsten Schlomm; Robert G. Bristow; Christopher M. Hovens; Ros A. Eeles; Colin S. Cooper; Clarissa Gerhauser; Geoff Macintyre; Andreas J. Gruber; David C. Wedge; Joachim Weischenfeldt; Jüri Reimand
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errSave
Recurrent mechanisms of biallelic epigenetic inactivation reveal new putative tumour suppressor genes in prostate cancer
errNature Communications
IF15.7
err2026-09-09
err0
errOAAI
errDaria Kiriy; Francesco Favero; Clarissa Gerhäuser; Jessica Heilmann; Pavlo Lutsik; Francisco German Rodriguez Gonzalez; Alessio Locallo; Jakob Schmidt Jespersen; Andreas J. Gruber; Andre V. Olsen; Barbara Hernando; Kevin CL Cheng; Diogo Pellegrina; Geoff Macintyre; G. Steven Bova; Daniel S. Brewer; Robert G. Bristow; Mark N. Brook; Benedikt Brors; Adam Butler; Géraldine Cancel-Tassin; Niall M. Corcoran; Olivier Cussenot; Ros A. Eeles; Abraham Gihawi; Etsehiwot G. Girma; Vincent J. Gnanapragasam; Anis Hamid; Vanessa M. Hayes; Housheng Hansen He; Christopher M. Hovens; Eddie L. Imada; G. Maria Jakobsdottir; Chol-Hee Jung; Francesca Khani; Zsofia Kote-Jarai; Philippe P. Lamy; Gregory Leeman; Massimo Loda; Luigi Marchionni; Ramyar Molania; Anthony T. Papenfuss; Bernard Pope; Lucio R. Queiroz; Tobias Rausch; Brian Robinson; Atef Sahli; Karina D. Sørensen; Sebastian Uhrig; David C. Wedge; Yaobo Xu; Takafumi N. Yamaguchi; Claudio Zanettini; Colin S. Cooper; Thorsten Schlomm; Jüri Reimand; Joachim Weischenfeldt
errShare
errSave
Integrated signatures define mutational processes in prostate cancer
errNature
IF48.5
err2026-09-09
err0
errOAAI
errAndreas J. Gruber; André V. Olsen; Barbara Hernando; Kevin C. L. Cheng; Clarissa Gerhäuser; Marina Torres; Francesco Favero; Daria Kiriy; Ángel Fernández-Sanromán; Juan Maria Roldan-Romero; Lucy Barton; Diogo Pellegrina; G. Steven Bova; Daniel S. Brewer; Mark N. Brook; Benedikt Brors; Adam Butler; Géraldine Cancel-Tassin; Niall M. Corcoran; Olivier Cussenot; Abraham Gihawi; Etsehiwot G. Girma; Vincent J. Gnanapragasam; Anis A. Hamid; Vanessa M. Hayes; Housheng Hansen He; Christopher M. Hovens; Eddie L. Imada; G. Maria Jakobsdottir; Chol-Hee Jung; Francesca Khani; Zsofia Kote-Jarai; Philippe Lamy; Gregory Leeman; Massimo Loda; Pavlo Lutsik; Luigi Marchionni; Ramyar Molania; Anthony T. Papenfuss; Bernard Pope; Lucio R. Queiroz; Tobias Rausch; Brian Robinson; Atef Sahli; Karina D. Sørensen; Takafumi N. Yamaguchi; Sebastian Uhrig; Yaobo Xu; Claudio Zanettini; Ronald Simon; Guido Sauter; Ros A. Eeles; Colin S. Cooper; Robert G. Bristow; David C. Wedge; Thorsten Schlomm; Geoff Macintyre; Jüri Reimand; Joachim Weischenfeldt
errShare
errSave
The Knowledge Connector decision support system for multiomics-based precision oncology
errNature Communications
IF15.7
err2026-01-19
err0
errOAAI
errDaniel Hübschmann; Simon Kreutzfeldt; Benjamin Roth; Katrin Glocker; Janine Schoop; Lena Oeser; Steffen Hausmann; Christian Koch; Sebastian Uhrig; Jennifer Hüllein; Barbara Hutter; Martina Fröhlich; Christoph E. Heilig; Maria-Veronica Teleanu; Daniel B. Lipka; Irina A. Kerle; Annika Baude-Müller; Katja Beck; Christoph Heining; Hanno Glimm; Frank Ückert; Alexander Knurr; Stefan Fröhling; Peter Horak
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Multi-omic profiling in cholangiocarcinoma to enable scientific advancement within the DKFZ/NCT/DKTK MASTER study
errANNALS OF ONCOLOGY
IF65.4
err2024-09-01
err0
PREAI
errNichetti, F.; Korell, F.; Schwab, M.; Hoffmeister, P. K. M.; Huellein, J.; Uhrig, S.; Teleanu, M-V; Kreutzfeldt, S.; Horak, P.; Glimm, H.; Heining, C.; Rieke, D. T.; Kindler, T.; Huebschmann, D.; Springfeld, C.; Jenzer, M.; Heilig, C. E.; Froehling, S.; Koehler, B. C.
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Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification (vol 14, 4632, 2023)
errNATURE COMMUNICATIONS
IF15.7
err2024-03-15
err0
errOAAI
errTretter, Celina; Kraetzig, Niklas de Andrade; Pecoraro, Matteo; Lange, Sebastian; Seifert, Philipp; von Frankenberg, Clara; Untch, Johannes; Zuleger, Gabriela; Wilhelm, Mathias; Zolg, Daniel P.; Dreyer, Florian S.; Braeunlein, Eva; Engleitner, Thomas; Uhrig, Sebastian; Boxberg, Melanie; Steiger, Katja; Slotta-Huspenina, Julia; Ochsenreither, Sebastian; von Bubnoff, Nikolas; Bauer, Sebastian; Boerries, Melanie; Jost, Philipp J.; Schenck, Kristina; Dresing, Iska; Bassermann, Florian; Friess, Helmut; Reim, Daniel; Gruetzmann, Konrad; Pfuetze, Katrin; Klink, Barbara; Schroeck, Evelin; Haller, Bernhard; Kuster, Bernhard; Mann, Matthias; Weichert, Wilko; Froehling, Stefan; Rad, Roland; Hiltensperger, Michael; Krackhardt, Angela M.
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Multi-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions
errNATURE COMMUNICATIONS
IF15.7
err2024-01-02
err3
errOAAI
errSchoepf, Julia; Uhrig, Sebastian; Heilig, Christoph E.; Lee, Kwang-Seok; Walther, Tatjana; Carazzato, Alexander; Dobberkau, Anna Maria; Weichenhan, Dieter; Plass, Christoph; Hartmann, Mark; Diwan, Gaurav D.; Carrero, Zunamys, I; Ball, Claudia R.; Hohl, Tobias; Kindler, Thomas; Rudolph-Haehnel, Patricia; Helm, Dominic; Schneider, Martin; Nilsson, Anna; Ora, Ingrid; Imle, Roland; Banito, Ana; Russell, Robert B.; Jones, Barbara C.; Lipka, Daniel B.; Glimm, Hanno; Huebschmann, Daniel; Hartmann, Wolfgang; Froehling, Stefan; Scholl, Claudia
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NCT/DKFZ MASTER handbook of interpreting whole-genome, transcriptome, and methylome data for precision oncology
errNPJ PRECISION ONCOLOGY
IF8
err2023-10-26
err7
errOAAI
errMock, Andreas; Teleanu, Maria-Veronica; Kreutzfeldt, Simon; Heilig, Christoph E.; Huellein, Jennifer; Moehrmann, Lino; Jahn, Arne; Hanf, Dorothea; Kerle, Irina A.; Singh, Hans Martin; Hutter, Barbara; Uhrig, Sebastian; Froehlich, Martina; Neumann, Olaf; Hartig, Andreas; Brueckmann, Sascha; Hirsch, Steffen; Grund, Kerstin; Dikow, Nicola; Lipka, Daniel B.; Renner, Marcus; Bhatti, Irfan Ahmed; Apostolidis, Leonidas; Schlenk, Richard F.; Schaaf, Christian P.; Stenzinger, Albrecht; Schroeck, Evelin; Huebschmann, Daniel; Heining, Christoph; Horak, Peter; Glimm, Hanno; Froehling, Stefan
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Detection of gene fusion-induced neoepitopes in dedifferentiated liposarcoma
errANNALS OF ONCOLOGY
IF65.4
err2023-10-01
err0
PREAI
errHorak, P.; Becker, J.; Blobner, S.; Weber, D.; Uhrig, S.; Foerster, J.; Raveendran, A.; Baude, A.; Wagner, J.; Poschke, I.; Zoernig, I.; Volkmar, M.; Platten, M.; Jaeger, D.; Froehling, S.; Chudasama, P.; Riemer, A.
errShare
errSave
Signaling-induced systematic repression of miRNAs uncovers cancer vulnerabilities and targeted therapy sensitivity
errCELL REPORTS MEDICINE
IF10.6
err2023-10-01
err3
errOAAI
errWurm, Alexander A.; Brilloff, Silke; Kolovich, Sofia; Schaefer, Silvia; Rahimian, Elahe; Kufrin, Vida; Bill, Marius; Carrero, Zunamys I.; Drukewitz, Stephan; Krueger, Alexander; Huether, Melanie; Uhrig, Sebastian; Oster, Sandra; Westphal, Dana; Meier, Friedegund; Pfutze, Katrin; Huebschmann, Daniel; Horak, Peter; Kreutzfeldt, Simon; Richter, Daniela; Schroeck, Evelin; Baretton, Gustavo; Heining, Christoph; Moehrmann, Lino; Froehling, Stefan; Ball, Claudia R.; Glimm, Hanno
errShare
errSave
Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification
errNATURE COMMUNICATIONS
IF15.7
err2023-08-02
err16
errOAAI
errTretter, Celina; Kraetzig, Niklas de Andrade; Pecoraro, Matteo; Lange, Sebastian; Seifert, Philipp; von Frankenberg, Clara; Untch, Johannes; Zuleger, Gabriela; Wilhelm, Mathias; Zolg, Daniel P. P.; Dreyer, Florian S. S.; Braeunlein, Eva; Engleitner, Thomas; Uhrig, Sebastian; Boxberg, Melanie; Steiger, Katja; Slotta-Huspenina, Julia; Ochsenreither, Sebastian; von Bubnoff, Nikolas; Bauer, Sebastian; Boerries, Melanie; Jost, Philipp J. J.; Schenck, Kristina; Dresing, Iska; Bassermann, Florian; Friess, Helmut; Reim, Daniel; Gruetzmann, Konrad; Pfuetze, Katrin; Klink, Barbara; Schroeck, Evelin; Haller, Bernhard; Kuster, Bernhard; Mann, Matthias; Weichert, Wilko; Froehling, Stefan; Rad, Roland; Hiltensperger, Michael; Krackhardt, Angela M. M.
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errSave
Genomics-based personalized oncology of advanced thymic epithelial tumors
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errMohrmann, Lino; Rostock, Lysann; Oles, Malgorzata; Jahn, Arne; Arlt, Marie; Paramasivam, Nagarajan; Johrens, Korinna; Rupp, Luise; Schmitz, Marc; Richter, Daniela; Uhrig, Sebastian; Frohlich, Martina; Hutter, Barbara; Hullein, Jennifer; Wolf, Elena E.; Hanf, Dorothea; Gieldon, Laura; Kreutzfeldt, Simon; Heilig, Christoph E.; Teleanu, Veronica; Lipka, Daniel B.; Mock, Andreas; Jelas, Ivan; Rieke, Damian T.; Wiesweg, Marcel; Boerries, Melanie; Illert, Anna L.; Desuki, Alexander; Kindler, Thomas; Krackhardt, Angela M.; Westphalen, C. Benedikt; Grosch, Heidrun; Apostolidis, Leonidas; Stenzinger, Albrecht; Kerle, Irina A.; Heining, Christoph; Hubschmann, Daniel; Schrock, Evelin; Frohling, Stefan; Glimm, Hanno
errShare
errSave
Genomic, transcriptomic, functional, and mechanistic characterization of rhabdomyosarcoma with FUS-TFCP2 or EWSR1-TFCP2 fusions
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errSchoepf, Julia; Uhrig, Sebastian; Heilig, Christoph E.; Lee, Kwang-Seok; Walther, Tatjana; Carazzato, Alexander; Dobberkau, Anna Maria; Weichenhan, Dieter; Plass, Christoph; Hartmann, Mark; Diwan, Gaurav; Carrero, Zunamys; Ball, Claudia R.; Hohl, Tobias; Kindler, Thomas; Rudolph-Hahnel, Patricia; Nilsson, Anna; Ora, Ingrid; Imle, Roland; Banito, Ana; Russell, Robert; Jones, Barbara C.; Lipka, Daniel B.; Glimm, Hanno; Hubschmann, Daniel; Hartmann, Wolfgang; Frohling, Stefan; Scholl, Claudia
errShare
errSave
Comprehensive cancer predisposition testing within the prospective MASTER trial identifies hereditary cancer patients and supports treatment decisions for rare cancers
errANNALS OF ONCOLOGY
IF65.4
err2022-11-01
err28
errOAAI
errJahn, A.; Rump, A.; Widmann, T. J.; Heining, C.; Horak, P.; Hutter, B.; Paramasivam, N.; Uhrig, S.; Gieldon, L.; Drukewitz, S.; Kuebler, A.; Bermudez, M.; Hackmann, K.; Porrmann, J.; Wagner, J.; Arlt, M.; Franke, M.; Fischer, J.; Kowalzyk, Z.; William, D.; Weth, V.; Oster, S.; Froehlich, M.; Huellein, J.; Gonzalez, C. Valle; Kreutzfeldt, S.; Mock, A.; Heilig, C. E.; Lipka, D. B.; Moehrmann, L.; Hanf, D.; Oles, M.; Teleanu, V.; Allgaeuer, M.; Ruhnke, L.; Kutz, O.; Knurr, A.; Lassmann, A.; Endris, V.; Neumann, O.; Penzel, R.; Beck, K.; Richter, D.; Winter, U.; Wolf, S.; Pfuetze, K.; Geoerg, C.; Meissburger, B.; Buchhalter, I.; Augustin, M.; Aulitzky, W. E.; Hohenberger, P.; Kroiss, M.; Schirmacher, P.; Schlenk, R. F.; Keilholz, U.; Klauschen, F.; Folprecht, G.; Bauer, S.; Siveke, J. T.; Brandts, C. H.; Kindler, T.; Boerries, M.; Illert, A. L.; von Bubnoff, N.; Jost, P. J.; Metzeler, K. H.; Bitzer, M.; Schulze-Osthoff, K.; von Kalle, C.; Brors, B.; Stenzinger, A.; Weichert, W.; Huebschmann, D.; Froehling, S.; Glimm, H.; Schroeck, E.; Klink, B.
errShare
errSave
Bcl-xL as prognostic marker and potential therapeutic target in cholangiocarcinoma
errLIVER INTERNATIONAL
IF5.2
err2022-09-14
err7
errOAAI
errHoffmeister-Wittmann, Paula; Mock, Andreas; Nichetti, Federico; Korell, Felix; Heilig, Christop E.; Scherr, Anna-Lena; Gunther, Michael; Albrecht, Thomas; Kelmendi, Eblina; Xu, Kaiyu; Nader, Luisa; Kessler, Annika; Schmitt, Nathalie; Fritzsche, Sarah; Weiler, Sofia; Sobol, Benjamin; Stenzinger, Albrecht; Boeck, Stefan; Westphalen, Christoph B.; Schulze-Osthoff, Klaus; Trojan, Jorg; Kindler, Thomas; Weichert, Wilko; Spiekermann, Karsten; Bitzer, Michael; Folprecht, Gunnar; Illert, Anna-Lena; Boerries, Melanie; Klauschen, Frederick; Ochsenreiter, Sebastian; Siveke, Jens; Bauer, Sebastian; Glimm, Hanno; Brors, Benedikt; Huellein, Jennifer; Huebschmann, Daniel; Uhrig, Sebastian; Horak, Peter; Kreutzfeld, Simon; Banales, Jesus M.; Springfeld, Christoph; Jaeger, Dirk; Schirmacher, Peter; Roessler, Stephanie; Ormanns, Steffen; Goeppert, Benjamin; Froehling, Stefan; Koehler, Bruno C.
errShare
errSave
Comprehensive genomic and epigenomic analysis in cancer of unknown primary guides molecularly- informed therapies despite heterogeneity
errNATURE COMMUNICATIONS
IF15.7
err2022-08-02
err27
errOAAI
errMoehrmann, Lino; Werner, Maximilian; Oles, Malgorzata; Mock, Andreas; Uhrig, Sebastian; Jahn, Arne; Kreutzfeldt, Simon; Froehlich, Martina; Hutter, Barbara; Paramasivam, Nagarajan; Richter, Daniela; Beck, Katja; Winter, Ulrike; Pfuetze, Katrin; Heilig, Christoph E.; Teleanu, Veronica; Lipka, Daniel B.; Zapatka, Marc; Hanf, Dorothea; List, Catrin; Allgaeuer, Michael; Penzel, Roland; Ruter, Gina; Jelas, Ivan; Hamacher, Rainer; Falkenhorst, Johanna; Wagner, Sebastian; Brandts, Christian H.; Boerries, Melanie; Illert, Anna L.; Metzeler, Klaus H.; Westphalen, C. Benedikt; Desuki, Alexander; Kindler, Thomas; Folprecht, Gunnar; Weichert, Wilko; Brors, Benedikt; Stenzinger, Albrecht; Schroeck, Evelin; Huebschmann, Daniel; Horak, Peter; Heining, Christoph; Froehling, Stefan; Glimm, Hanno
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Genomic architecture of FGFR2 fusions in cholangiocarcinoma and its implication for molecular testing
errBRITISH JOURNAL OF CANCER
IF6.8
err2022-07-23
err35
errOAAI
errNeumann, Olaf; Burn, Timothy C.; Allgaeuer, Michael; Ball, Markus; Kirchner, Martina; Albrecht, Thomas; Volckmar, Anna-Lena; Beck, Susanne; Endris, Volker; Goldschmid, Hannah; Lehmann, Ulrich; Seker-Cin, Huriye; Uhrig, Sebastian; Roessler, Stephanie; Budczies, Jan; Froehling, Stefan; Longerich, Thomas; Wagner, Alex H.; Vogel, Arndt; Schirmacher, Peter; Stenzinger, Albrecht; Kazdal, Daniel
errShare
errSave
MCL1 as putative target in pancreatoblastoma
errVIRCHOWS ARCHIV
IF3.1
err2022-06-07
err5
errOAAI
errReissig, Timm M.; Uhrig, Sebastian; Jost, Philipp J.; Luchini, Claudio; Vicentini, Caterina; Liffers, Sven-Thorsten; Allgaeuer, Michael; Adsay, Volkan; Scarpa, Aldo; Lawlor, Rita Teresa; Froehling, Stefan; Stenzinger, Albrecht; Kloeppel, Gunter; Schildhaus, Hans-Ulrich; Siveke, Jens T.
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The genomic and transcriptional landscape of primary central nervous system lymphoma
errNATURE COMMUNICATIONS
IF15.7
err2022-05-10
err65
errOAAI
errRadke, Josefine; Ishaque, Naveed; Koll, Randi; Gu, Zuguang; Schumann, Elisa; Sieverling, Lina; Uhrig, Sebastian; Huebschmann, Daniel; Toprak, Umut H.; Lopez, Cristina; Hostench, Xavier Pastor; Borgoni, Simone; Juraeva, Dilafruz; Pritsch, Fabienne; Paramasivam, Nagarajan; Balasubramanian, Gnana Prakash; Schlesner, Matthias; Sahay, Shashwat; Weniger, Marc; Pehl, Debora; Radbruch, Helena; Osterloh, Anja; Korfel, Agnieszka; Misch, Martin; Onken, Julia; Faust, Katharina; Vajkoczy, Peter; Moskopp, Dag; Wang, Yawen; Joedicke, Andreas; Truemper, Lorenz; Anagnostopoulos, Ioannis; Lenze, Dido; Kueppers, Ralf; Hummel, Michael; Schmitt, Clemens A.; Wiestler, Otmar D.; Wolf, Stephan; Unterberg, Andreas; Eils, Roland; Herold-Mende, Christel; Brors, Benedikt; Siebert, Reiner; Wiemann, Stefan; Heppner, Frank L.
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errSave
Deconvolution of sarcoma methylomes reveals varying degrees of immune cell infiltrates with association to genomic aberrations (vol 19, 204, 2021)
errJOURNAL OF TRANSLATIONAL MEDICINE
IF7.5
err2022-04-02
err0
errOAAI
errSimon, Malte; Mughal, Sadaf S.; Horak, Peter; Uhrig, Sebastian; Buchloh, Jonas; Aybey, Bogac; Stenzinger, Albrecht; Glimm, Hanno; Froehling, Stefan; Brors, Benedikt; Imbusch, Charles D.
errShare
errSave

Research Directions

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