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Genomic, Phenomic, and Geographic Relationships with Leukocyte Telomere Length in the US Yields New Insights for Neoplasms and Cardiometabolic Disease Nakao, Tetsushi; Koyama, Satoshi; Truong, Buu; Uddin, Mesbah; Misra, Anika; Patel, Aniruddh; Vlasschaert, Caitlyn; Bick, Alexander; Codd, Veryan; Samani, Nilesh; Hornsby, Whitney; Ellinor, Patrick; Natarajan, Pradeep Share Save
Polygenic risk score adds to a clinical risk score in the prediction of cardiovascular disease in a clinical setting Samani, Nilesh J.; Beeston, Emma; Greengrass, Chris; Riveros-McKay, Fernando; Debiec, Radoslaw; Lawday, Daniel; Wang, Qingning; Budgeon, Charley A.; Braund, Peter S.; Bramley, Richard; Kharodia, Shireen; Newton, Michelle; Marshall, Andrea; Krzeminski, Andre; Zafar, Azhar; Chahal, Anuj; Heer, Amadeeep; Khunti, Kamlesh; Joshi, Nitin; Lakhani, Mayur; Farooqi, Azhar; Plagnol, Vincent; Donnelly, Peter; Weale, Michael E.; Nelson, Christopher P. Share Save
Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits Keaton, Jacob M.; Kamali, Zoha; Xie, Tian; Vaez, Ahmad; Williams, Ariel; Goleva, Slavina B.; Ani, Alireza; Evangelou, Evangelos; Hellwege, Jacklyn N.; Yengo, Loic; Young, William J.; Traylor, Matthew; Giri, Ayush; Zheng, Zhili; Zeng, Jian; Chasman, Daniel I.; Morris, Andrew P.; Caulfield, Mark J.; Hwang, Shih-Jen; Kooner, Jaspal S.; Conen, David; Attia, John R.; Morrison, Alanna C.; Loos, Ruth J. F.; Kristiansson, Kati; Schmidt, Reinhold; Hicks, Andrew A.; Pramstaller, Peter P.; Nelson, Christopher P.; Samani, Nilesh J.; Risch, Lorenz; Gyllensten, Ulf; Melander, Olle; Riese, Harriette; Wilson, James F.; Campbell, Harry; Rich, Stephen S.; Psaty, Bruce M.; Lu, Yingchang; Rotter, Jerome I.; Guo, Xiuqing; Rice, Kenneth M.; Vollenweider, Peter; Sundstrom, Johan; Langenberg, Claudia; Tobin, Martin D.; Giedraitis, Vilmantas; Luan, Jian'an; Tuomilehto, Jaakko; Kutalik, Zoltan; Ripatti, Samuli; Salomaa, Veikko; Girotto, Giorgia; Trompet, Stella; Jukema, J. Wouter; van der Harst, Pim; Ridker, Paul M.; Giulianini, Franco; Vitart, Veronique; Goel, Anuj; Watkins, Hugh; Harris, Sarah E.; Deary, Ian J.; van der Most, Peter J.; Oldehinkel, Albertine J.; Keavney, Bernard D.; Hayward, Caroline; Campbell, Archie; Boehnke, Michael; Scott, Laura J.; Boutin, Thibaud; Mamasoula, Chrysovalanto; Jarvelin, Marjo-Riitta; Peters, Annette; Gieger, Christian; Lakatta, Edward G.; Cucca, Francesco; Hui, Jennie; Knekt, Paul; Enroth, Stefan; De Borst, Martin H.; Polasek, Ozren; Concas, Maria Pina; Catamo, Eulalia; Cocca, Massimiliano; Li-Gao, Ruifang; Hofer, Edith; Schmidt, Helena; Spedicati, Beatrice; Waldenberger, Melanie; Strachan, David P.; Laan, Maris; Teumer, Alexander; Dorr, Marcus; Gudnason, Vilmundur; Cook, James P.; Ruggiero, Daniela; Kolcic, Ivana; Boerwinkle, Eric; Traglia, Michela; Lehtimaki, Terho; Raitakari, Olli T.; Johnson, Andrew D.; Newton-Cheh, Christopher; Brown, Morris J.; Dominiczak, Anna F.; Sever, Peter J.; Poulter, Neil; Chambers, John C.; Elosua, Roberto; Siscovick, David; Esko, Tonu; Metspalu, Andres; Strawbridge, Rona J.; Laakso, Markku; Hamsten, Anders; Hottenga, Jouke-Jan; de Geus, Eco; Morris, Andrew D.; Palmer, Colin N. A.; Nolte, Ilja M.; Milaneschi, Yuri; Marten, Jonathan; Wright, Alan; Zeggini, Eleftheria; Howson, Joanna M. M.; O'Donnell, Christopher J.; Spector, Tim; Nalls, Mike A.; Simonsick, Eleanor M.; Liu, Yongmei; van Duijn, Cornelia M.; Butterworth, Adam S.; Danesh, John N.; Menni, Cristina; Wareham, Nicholas J.; Khaw, Kay-Tee; Sun, Yan V.; Wilson, Peter W. F.; Cho, Kelly; Visscher, Peter M.; Denny, Joshua C.; Levy, Daniel; Edwards, Todd L.; Munroe, Patricia B.; Snieder, Harold; Warren, Helen R. Share Save
Genetic imputation of kidney transcriptome, proteome and multi-omics illuminates new blood pressure and hypertension targets Xu, Xiaoguang; Khunsriraksakul, Chachrit; Eales, James M.; Rubin, Sebastien; Scannali, David; Saluja, Sushant; Talavera, David; Markus, Havell; Wang, Lida; Drzal, Maciej; Maan, Akhlaq; Lay, Abigail C.; Prestes, Priscilla R.; Regan, Jeniece; Diwadkar, Avantika R.; Denniff, Matthew; Rempega, Grzegorz; Ryszawy, Jakub; Krol, Robert; Dormer, John P.; Szulinska, Monika; Walczak, Marta; Antczak, Andrzej; Matias-Garcia, Pamela R.; Waldenberger, Melanie; Woolf, Adrian S.; Keavney, Bernard; Zukowska-Szczechowska, Ewa; Wystrychowski, Wojciech; Zywiec, Joanna; Bogdanski, Pawel; Danser, A. H. Jan; Samani, Nilesh J.; Guzik, Tomasz J.; Morris, Andrew P.; Liu, Dajiang J.; Charchar, Fadi J.; Tomaszewski, Maciej Share Save
Differential biomarker expression in heart failure patients with and without mitral regurgitation: Insights from BIOSTAT-CHF Adamo, Marianna; Pagnesi, Matteo; Di Pasquale, Mattia; Ravera, Alice; Dickstein, Kenneth; Ng, Leong L.; Anker, Stefan D.; Cleland, John G.; Filippatos, Gerasimos S.; Lang, Chim C.; Ponikowski, Piotr; Samani, Nilesh J.; Zannad, Faiez; van Veldhuisen, Dirk J.; Lipsic, Erik; Voors, Adriaan; Metra, Marco Share Save
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Clinical characteristics and prognosis of patients with heart failure and high concentrations of interleukin-17D Baumhove, Lukas; Bomer, Nils; Tromp, Jasper; van Essen, Bart J.; Dickstein, Kenneth; Cleland, John G.; Lang, Chim C.; Ng, Leong L.; Samani, Nilesh J.; Anker, Stefan D.; Metra, Marco; van Veldhuisen, Dirk J.; Van der Meer, Peter; Voors, Adriaan A. Share Save
Association of Longer Leukocyte Telomere Length With Cardiac Size, Function, and Heart Failure Aung, Nay; Wang, Qingning; van Duijvenboden, Stefan; Burns, Richard; Stoma, Svetlana; Raisi-Estabragh, Zahra; Ahmet, Selda; Allara, Elias; Wood, Angela; Di Angelantonio, Emanuele; Danesh, John; Munroe, Patricia B.; Young, Alistair; Harvey, Nicholas C.; Codd, Veryan; Nelson, Christopher P.; Petersen, Steffen E.; Samani, Nilesh J. Share Save
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Common genetic variations in telomere length genes and lung cancer: a Mendelian randomisation study and its novel application in lung tumour transcriptome Penha, Ricardo Cortez Cardoso; Smith-Byrne, Karl; Atkins, Joshua R.; Haycock, Philip C.; Kar, Siddhartha; Codd, Veryan; Samani, Nilesh J.; Nelson, Christopher; Milojevic, Maja; Gabriel, Aurelie A. G.; Amos, Christopher; Brennan, Paul; Hung, Rayjean J.; Kachuri, Linda; Mckay, James D. Share Save
Systemic oxidative stress associates with disease severity and outcome in patients with new-onset or worsening heart failure de Koning, Marie-Sophie L. Y.; Emmens, Johanna E.; Romero-Hernandez, Esteban; Bourgonje, Arno R.; Assa, Solmaz; Figarska, Sylwia M.; Cleland, John G. F.; Samani, Nilesh J.; Ng, Leong L.; Lang, Chim C.; Metra, Marco; Filippatos, Gerasimos S.; van Veldhuisen, Dirk J.; Anker, Stefan D.; Dickstein, Kenneth; Voors, Adriaan A.; Lipsic, Erik; van Goor, Harry; van der Harst, Pim Share Save
Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure Siedlinski, Mateusz; Carnevale, Lorenzo; Xu, Xiaoguang; Carnevale, Daniela; Evangelou, Evangelos; Caulfield, Mark J.; Maffia, Pasquale; Wardlaw, Joanna; Samani, Nilesh J.; Tomaszewski, Maciej; Lembo, Giuseppe; Holmes, Michael, V; Guzik, Tomasz J. Share Save
Cardiac Expression of ms1/STARS, a Novel Gene Involved in Cardiac Development and Disease, Is Regulated by GATA4 Ounzain, Samir; Kobayashi, Satoru; Peterson, Richard E.; He, Aibin; Motterle, Anna; Samani, Nilesh J.; Menick, Donald R.; Pu, William T.; Liang, Qiangrong; Chong, Nelson W. Share Save
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Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants Aragam, Krishna G.; Jiang, Tao; Goel, Anuj; Kanoni, Stavroula; Wolford, Brooke N.; Atri, Deepak S.; Weeks, Elle M.; Wang, Minxian; Hindy, George; Zhou, Wei; Grace, Christopher; Roselli, Carolina; Marston, Nicholas A.; Kamanu, Frederick K.; Surakka, Ida; Venegas, Loreto Munoz; Sherliker, Paul; Koyama, Satoshi; Ishigaki, Kazuyoshi; Asvold, Bjorn O.; Brown, Michael R.; Brumpton, Ben; de Vries, Paul S.; Giannakopoulou, Olga; Giardoglou, Panagiota; Gudbjartsson, Daniel F.; Gueldener, Ulrich; Haider, Syed M. Ijlal; Helgadottir, Anna; Ibrahim, Maysson; Kastrati, Adnan; Kessler, Thorsten; Kyriakou, Theodosios; Konopka, Tomasz; Li, Ling; Ma, Lijiang; Meitinger, Thomas; Mucha, Soeren; Munz, Matthias; Murgia, Federico; Nielsen, Jonas B.; Noethen, Markus M.; Pang, Shichao; Reinberger, Tobias; Schnitzler, Gavin; Smedley, Damian; Thorleifsson, Gudmar; von Scheidt, Moritz; Ulirsch, Jacob C.; Arnar, David O.; Burtt, Noel P.; Costanzo, Maria C.; Flannick, Jason; Ito, Kaoru; Jang, Dong-Keun; Kamatani, Yoichiro; Khera, Amit V.; Komuro, Issei; Kullo, Iftikhar J.; Lotta, Luca A.; Nelson, Christopher P.; Roberts, Robert; Thorgeirsson, Gudmundur; Thorsteinsdottir, Unnur; Webb, Thomas R.; Baras, Aris; Bjoerkegren, Johan L. M.; Boerwinkle, Eric; Dedoussis, George; Holm, Hilma; Hveem, Kristian; Melander, Olle; Morrison, Alanna C.; Orho-Melander, Marju; Rallidis, Loukianos S.; Ruusalepp, Arno; Sabatine, Marc S.; Stefansson, Kari; Zalloua, Pierre; Ellinor, Patrick T.; Farrall, Martin; Danesh, John; Ruff, Christian T.; Finucane, Hilary K.; Hopewell, Jemma C.; Clarke, Robert; Gupta, Rajat M.; Erdmann, Jeanette; Samani, Nilesh J.; Schunkert, Heribert; Watkins, Hugh; Willer, Cristen J.; Deloukas, Panos; Kathiresan, Sekar; Butterworth, Adam S. Share Save
The FES Gene at the 15q26 Coronary-Artery-Disease Locus Inhibits Atherosclerosis Karamanavi, Elisavet; McVey, David G.; van der Laan, Sander W.; Stanczyk, Paulina J.; Morris, Gavin E.; Wang, Yifan; Yang, Wei; Chan, Kenneth; Poston, Robin N.; Luo, Jun; Zhou, Xinmiao; Gong, Peng; Jones, Peter D.; Cao, Junjun; Kostogrys, Renata B.; Webb, Tom R.; Pasterkamp, Gerard; Yu, Haojie; Xiao, Qingzhong; Greer, Peter A.; Stringer, Emma J.; Samani, Nilesh J.; Ye, Shu Share Save
Heart failure with normal LVEF in BIOSTAT-CHF Baumhove, Lukas; Tromp, Jasper; Figarska, Sylwia; van Essen, Bart J.; Anker, Stefan D.; Dickstein, Kenneth; Cleland, John G.; Lang, Chim C.; Filippatos, Gerasimos; Ng, Leong L.; Samani, Nilesh J.; Metra, Marco; van Veldhuisen, Dirk J.; Lam, Carolyn S. P.; Voors, Adriaan A.; van Der Meer, Peter Share Save
Albuminuria as a marker of systemic congestion in patients with heart failure Boorsma, Eva M.; Ter Maaten, Jozine M.; Damman, Kevin; van Essen, Bart J.; Zannad, Faiez; van Veldhuisen, Dirk J.; Samani, Nilesh J.; Dickstein, Kenneth; Metra, Marco; Filippatos, Gerasimos; Lang, Chim C.; Ng, Leong; Anker, Stefan D.; Cleland, John G.; Pellicori, Pierpaolo; Gansevoort, Ron T.; Heerspink, Hiddo J. L.; Voors, Adriaan A.; Emmens, Johanna E. Share Save
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