Craig J. McClain - Publications, H-index & Citations

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Craig J. McClain

university of louisville

102H-index

919Paper Count

3.9WCitation Count

Published Papers 295

Publication Date

Sex differences in beneficial and pathogenic bacteria in People With HIV (PWH) with a history of heavy alcohol drinking

Frontiers in Microbiology

IF4.5

2025-11-22

OAAI

Aakarsha V. Rao†; Smita S. Ghare†; Vasuk Gautam; Kristi L. Hoffman; Joseph Petrosino; Kaku So-Armah; Jeffrey H. Samet; Gregory J. Patts; Debbie M. Cheng; Elena Blokhina; Evgeny M. Krupitsky; Dmitry Lioznov; Edwin Zvartau; Craig J. McClain; Hillary Tindle; Matthew S. Freiberg; Shirish S. Barve

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Intestinal Neutral Ceramidase Deficiency Triggers Regulatory T Cell Response via Gd3 to Protect the Host from Intestinal Inflammation

Advanced Science

IF14.1

2025-11-07

OAAI

Zhishan Xu; Chao Lei; Mukesh K Sriwastva; Ting Wang; Amanguli Tuohongerbieke; Xiaotong Song; Collin Noud; Shannon Derkson; Yi Tan; Gerald Dryden; Craig J McClain; Zhongbin Deng

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Elevated plasma soluble epoxide hydrolase was positively correlated with markers of liver injury and pro-inflammatory cytokines IL-8 and IL-1β in patients with alcohol-associated liver disease

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Warner, Dennis; McClain, Craig; Kirpich, Irina

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Optimization of Data-Dependent Acquisition Parameters in Mass Spectrometry for Oligonucleotide Identification

Journal of the American Society for Mass Spectrometry

IF2.7

2025-10-27

PREAI

Audriy Jebet; Xipeng Ma; Liqing He; Adam J. Anthony; Seongho Kim; Eugene Mueller; Craig J. McClain; Xiang Zhang

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Physical activity and advanced fibrosis in MASLD, MetALD, and ALD in a nationally representative cohort: NHANES 2017–2020

Hepatology Communications

IF4.6

2025-10-14

OAAI

Dunn, Nicholas; Zhang, Wanyu; Blaney, Hanna L.; Diaz, Luis Antonio; Patel, Arpan; Wong, Robert J.; Arab, Juan Pablo; Younossi, Zobair; McClain, Craig; Kong, Maiying; Singal, Ashwani K.

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Hepatocyte-Specific Transcriptional Responses to Liver-Targeted Delivery of a Soluble Epoxide Hydrolase Inhibitor in a Mouse Model of Alcohol-Associated Liver Disease

Biology 2025, Vol. 14, Page 1267

IF3.5

2025-09-29

OAAI

Dennis R. Warner; Jeffrey B. Warner; Josiah E. Hardesty; Yasmeen Abdelfadil; Chirag Soni; Philip Bauer; Claudio Maldonado; Craig J. McClain; Irina A. Kirpich

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Clinical trial design, biomarkers and end points in metabolic and alcohol-related liver disease

Nature Reviews Gastroenterology & Hepatology

IF51

2025-09-26

PREAI

Luis Antonio Diaz; Maja Thiele; Alexandre Louvet; Brian P. Lee; Veeral Ajmera; Federica Tavaglione; Cynthia L. Hsu; Daniel Q. Huang; Elisa Pose; Ramon Bataller; Craig McClain; Jessica Mellinger; Monica Tincopa; Mack C. Mitchell; Vlad Ratziu; Mary E. Rinella; Shiv K. Sarin; Vijay H. Shah; Gyongyi Szabo; Vincent Wai-Sun Wong; Meena B. Bansal; Lorenzo Leggio; Patrick S. Kamath; Aleksander Krag; Arun J. Sanyal; Marco Arrese; Juan Pablo Arab; Quentin M. Anstee; Philippe Mathurin; Rohit Loomba

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Natural history and development of a novel composite endpoint in patients with alcohol-associated hepatitis: Data from a prospective multicenter study

HEPATOLOGY

IF15.8

2025-09-01

PREAI

Dasarathy, Srinivasan; Tu, Wanzhu; Welch, Nicole; Gawrieh, Samer; Yu, Yunpeng; Tang, Qing; Kettler, Carla; Sanyal, Arun J.; Szabo, Gyongyi; Shah, Vijay H.; Bataller, Ramon; Nagy, Laura E.; Mcclain, Craig J.; Chalasani, Naga; Kerr, Thomas; Mitchell, Mack C.

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Chronic and Heavy Drinking, Nutrition Status, and Progression of Liver Injury Negatively Affect the Mortality Risk in Patients Suffering from Alcohol-Associated Hepatitis

Journal of Clinical Medicine 2025, Vol. 14, Page 6157

IF2.9

2025-09-01

OAAI

Aishwarya Thakurdesai; Anjali Kumari; Henry Shay; Khaled Elgharabawy; Evan J. Winrich; Wanyu Zhang; Amber Jackson; Matthew C. Cave; Maiying Kong; Xiang Zhang; Ashwani K. Singal; Craig J. McClain; Vatsalya Vatsalya

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Effects of soluble epoxide hydrolase inhibition on liver injury and gut microbiota in mice chronically fed ethanol

alcohol clinical and experimental research

IF0

2025-07-03

PREAI

Dennis R. Warner; Jeffrey B. Warner; Yasmeen Abdelfadil; Josiah E. Hardesty; Rui Treves; Chao Lei; Hannah E. Hanford; Craig J. McClain; Irina A. Kirpich

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Perfluorooctane sulfonate exposure and alcohol-associated liver disease severity in a mouse chronic-binge ethanol feeding model

TOXICOLOGICAL SCIENCES

IF4.1

2025-06-01

PREAI

Ekuban, Frederick A.; Gripshover, Tyler C.; Ames, Paxton; Biswas, Kushal; Bolatimi, Oluwanifemi E.; Abramson, Joshua; Iyer, Megana; Luo, Jianzhu; Ekuban, Abigail; Hwang, Jae Yeon; Park, Juw Won; Banerjee, Mayukh; Watson, Walter H.; Wahlang, Banrida; Bello, Dhimiter; Schlezinger, Jennifer J.; Mcclain, Craig J.; Cave, Matthew C.

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ACG Clinical Guideline: Malnutrition and Nutritional Recommendations in Liver Disease

AMERICAN JOURNAL OF GASTROENTEROLOGY

IF7.6

2025-05-02

PREAI

Singal, AK; Wong, RJ; Dasarathy, S; Abdelmalek, MF; Neuschwander-Tetri, BA; Limketkai, BN; Petrey, J; Mcclain, CJ

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Impact of chronic ethanol consumption and SARS-COV-2 on the liver and intestine: A pilot dose-response study in mice

ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH

IF2.7

2025-01-05

PREAI

Ghare, Smita; Warner, Dennis; Warner, Jeffrey; Chilton, Paula M.; Lee, Jiyeon; Zhang, Jingwen; Wang, Min; Hardesty, Josiah; Treves, Rui; Gabbard, Jon; Anderson, Charles; Batra, Lalit; Sreenivasan, Chithra; Kraenzle, Jennifer; Mcculley, Matthew; Mccoy, Stephanie; Zhang, Lihua; Feng, Wenke; Gondim, Dibson Dibe; Barve, Shirish; Zheng, Jian; Palmer, Kenneth; Mcclain, Craig; Kirpich, Irina

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Intestine epithelial-specific hypoxia-inducible factor-1α overexpression ameliorates western diet-induced MASLD

HEPATOLOGY COMMUNICATIONS

IF4.6

2024-12-01

OAAI

Xu, Manman; Taylor, Madison S.; Hill, Bradford G.; Li, Xiaohong; Rouchka, Eric C.; Mcclain, Craig J.; Song, Ming

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Visium spatial transcriptomics and proteomics identifies novel hepatic cell populations and transcriptomic signatures of alcohol-associated hepatitis

ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH

IF2.7

2024-11-26

OAAI

Gripshover, Tyler C.; Treves, Rui S.; Rouchka, Eric C.; Chariker, Julia H.; Zheng, Shirong; Hudson, Elizabeth; Smith, Melissa L.; Singal, Ashwani K.; Mcclain, Craig J.; Hardesty, Josiah E.

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Multiomics Studies on Metabolism Changes in Alcohol-Associated Liver Disease

JOURNAL OF PROTEOME RESEARCH

IF3.6

2024-10-17

PREAI

He, Liqing; Xu, Raobo; Ma, Xipeng; Yin, Xinmin; Mueller, Eugene; Feng, Wenke; Menze, Michael; Kim, Seongho; Mcclain, Craig J.; Zhang, Xiang

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The Modulatory Effects and Therapeutic Potential of Cannabidiol in the Gut

CELLS

IF5.2

2024-09-26

OAAI

Brown, Kevin; Funk, Kyle; Barrientos, Alexa Figueroa; Bailey, Ashly; Shrader, Sarah; Feng, Wenke; McClain, Craig J.; Song, Zhao-Hui

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Age-associated temporal decline in butyrate-producing bacteria plays a key pathogenic role in the onset and progression of neuropathology and memory deficits in 3xTg-AD mice

GUT MICROBES

IF11

2024-08-25

OAAI

Chilton, Paula M.; Ghare, Smita S.; Charpentier, Benjamin T.; Myers, Scott A.; Rao, Aakarsha V.; Petrosino, Joseph F.; Hoffman, Kristi L.; Greenwell, John C.; Tyagi, Neetu; Behera, Jyotirmaya; Wang, Yali; Sloan, Lucy J.; Zhang, JingWen; Shields, Christopher B.; Cooper, Gregory E.; Gobejishvili, Leila; Whittemore, Scott R.; McClain, Craig J.; Barve, Shirish S.

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Back to phosphodiesterase inhibitors for liver disease: Are we ready for clinical trials?

HEPATOLOGY

IF15.8

2024-08-08

OAAI

Gobejishvili, Leila; McClain, Craig J.

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A plasma peptidomic signature reveals extracellular matrix remodeling and predicts prognosis in alcohol-associated hepatitis

HEPATOLOGY COMMUNICATIONS

IF4.6

2024-08-01

OAAI

Sayed, Khaled; Dolin, Christine E.; Wilkey, Daniel W.; Li, Jiang; Sato, Toshifumi; Beier, Juliane I.; Argemi, Josepmaria; Vatsalya, Vatsalya; McClain, Craig J.; Bataller, Ramon; Wahed, Abdus S.; Merchant, Michael L.; Benos, Panayiotis V.; Arteel, Gavin E.

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Research Directions