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H

Howard A. Young

nci at frederick

108H-index
598Paper Count
3.8WCitation Count
Published Papers 191
Publication Date
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Dysbiosis-induced expansion of AXL-positive inflammatory type 3 dendritic cells triggers preclinical autoimmunity
errNature Immunology
IF27.6
err2026-07-21
err0
errOAAI
errGrozdan Cvijetic; Valentina Ottaviani; Isabella O. Conway; Erfan Jabari; Mladen Mitrovic; Haiting Wang; Patrick Fernandes Rodrigues; Anastasia du Halgouet; Siqi Zhao; Harrison C. Wang; Anjali P. Chandroth; Robert J. Palmer; Eduard Ansaldo; Andrew D. Doyle; Daniel Martin; Roman Szabo; Cristina Corsino; Francesca Pala; Miriam R. Fernandes; Nicolas Bouladoux; Howard A. Young; Yufan Zheng; Zhaoyuan Liu; Florent Ginhoux; Eric V. Dang; Stephen Darnell; George Liechti; Michail S. Lionakis; Robert Ivanek; Luigi D. Notarangelo; Yasmine Belkaid; WanJun Chen; Amiran Dzutsev; Giorgio Trinchieri; Roxane Tussiwand
errShare
errSave
Cytotoxic CD4⁺ T cells exhibit an immunosuppressive shift in checkpoint immunotherapy resistance in melanoma patients
errcancer immunology immunotherapy
IF0
err2025-09-04
err0
errOAAI
errHeekyong R. Bae; Byeongchan Son; Kyoungho Hwang; Suntae Kim; Howard A. Young; Eun-Young Kwon
errShare
errSave
Chronic Low-Level IFN-γ Expression Disrupts Mitochondrial Complex I Activity in Renal Macrophages: An Early Mechanistic Driver of Lupus Nephritis Pathogenesis
errINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
IF4.9
err2024-12-25
err0
errOAAI
errBae, Heekyong R.; Shin, Su-Kyung; Lee, Ji-Yoon; Ko, Yeo Jin; Kim, Suntae; Young, Howard A.; Kwon, Eun-Young
errShare
errSave
Interleukin-2-mediated NF-κB-dependent mRNA splicing modulates interferon gamma protein production
errEMBO REPORTS
IF6.2
err2024-11-22
err0
PREAI
errVan Gelder, Rachel D.; Gokhale, Nandan S.; Genoyer, Emmanuelle; Omelia, Dylan S.; Anderson, Stephen K.; Young, Howard A.; Savan, Ram
errShare
errSave
Dietary therapy of murine primary biliary cholangitis induces hepatocellular steatosis: A cautionary tale
errLIVER INTERNATIONAL
IF5.2
err2024-08-05
err1
errOAAI
errZhang, Weici; Al Tekreeti, Taha; Leung, Patrick S. C.; Tsuneyama, Koichi; Dhillon, Harleen; Rojas, Manuel; Heuer, Luke S.; Ridgway, William M.; Ansari, Aftab A.; Young, Howard A.; Mackay, Charles R.; Gershwin, M. Eric
errShare
errSave
Joost Oppenheim: A pioneer of cytokine research
errCYTOKINE
IF3.7
err2024-05-01
err0
PREAI
errKalvakolanu, Dhan, V; Young, Howard A.; Durum, Scott
errShare
errSave
Aberrant CD8+T cells drive reproductive dysfunction in female mice with elevated IFN-γ levels
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-04-18
err1
errOAAI
errBafor, Enitome E.; Erwin-Cohen, Rebecca A.; Martin, Toni; Baker, Clayton; Kimmel, Adrienne E.; Duverger, Olivier; Fenimore, John M.; Ramba, Meredith; Spindel, Thea; Hess, Megan M.; Sanford, Michael; Lazarevic, Vanja; Benayoun, Berenice A.; Young, Howard A.; Valencia, Julio C.
errShare
errSave
D-Allulose Ameliorates Dysregulated Macrophage Function and Mitochondrial NADH Homeostasis, Mitigating Obesity-Induced Insulin Resistance
errNUTRIENTS
IF5
err2023-09-29
err9
errOAAI
errBae, Heekyong R.; Shin, Su-Kyung; Han, Youngji; Yoo, Ji-Hyeon; Kim, Suntae; Young, Howard A.; Kwon, Eun-Young
errShare
errSave
IL-15 Priming Alters IFN-γ Regulation in Murine NK Cells
errJOURNAL OF IMMUNOLOGY
IF3.4
err2023-09-25
err5
errOAAI
errCimpean, Maria; Keppel, Molly P.; Gainullina, Anastasiia; Fan, Changxu; Sohn, Hyogon; Schedler, Nathan C.; Swain, Amanda; Kolicheski, Ana; Shapiro, Hannah; Young, Howard A.; Wang, Ting; Artyomov, Maxim N.; Cooper, Megan A.
errShare
errSave
Chronic inflammation in high-fat diet-fed mice: Unveiling the early pathogenic connection between liver and adipose tissue
errJOURNAL OF AUTOIMMUNITY
IF7
err2023-09-01
err11
errOAAI
errBae, Heekyong R.; Shin, Su-Kyung; Yoo, Ji-Hyeon; Kim, Suntae; Young, Howard A.; Kwon, Eun-Young
errShare
errSave
Male-biased metabolic and structural muscular changes driven by testosterone flare-like conditions
errCANCER RESEARCH
IF16.6
err2023-06-02
err0
PREAI
errFenimore, John M.; Springer, Danielle; Edmonston, Elijah; Nagashima, Kunio; Sowalsky, Adam; Young, Howard
errShare
errSave
The adaptor protein TRAF3 is an immune checkpoint that inhibits myeloid-derived suppressor cell expansion
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2023-05-03
err3
errOAAI
errZhu, Sining; Lalani, Almin I.; Jin, Juan; Sant'Angelo, Derek; Covey, Lori R.; Liu, Kebin; Young, Howard A.; Ostrand-Rosenberg, Suzanne; Xie, Ping
errShare
errSave
Loss of FOXP3+CD25+Tregs is independent of type I interferon signaling in lupus-prone mice
errJOURNAL OF IMMUNOLOGY
IF3.4
err2023-05-01
err0
errOAAI
errNguyen, Ngoc Thuy; Valencia, Julio Cesar; Ramba, Meredith; Young, Howard A.
errShare
errSave
IFN-γ and androgens disrupt mitochondrial function in murine myocytes
errJOURNAL OF PATHOLOGY
IF5.2
err2023-04-27
err4
PREAI
errFenimore, John M.; Springer, Danielle A.; Romero, Maria E.; Edmondson, Elijah F.; McVicar, Dan W.; Yanpallewar, Sudhirkumar; Sanford, Michael; Spindel, Thea; Engle, Elizabeth; Meyer, Thomas J.; Valencia, Julio C.; Young, Howard A.
errShare
errSave
IL-27 induces an IFN-like signature in murine macrophages which in turn modulate colonic epithelium
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2023-04-20
err3
errOAAI
errAndrews, Caroline; McLean, Mairi H.; Hixon, Julie A.; Pontejo, Sergio M.; Starr, Tregei; Malo, Courtney; Cam, Margaret; Ridnour, Lisa; Hickman, Heather; Steele-Mortimer, Olivia; Wink, David A.; Young, Howard A.; McVicar, Daniel W.; Li, Wenqing; Durum, Scott K.
errShare
errSave
Interrogating subclonal mechanisms of immune evasion and immunotherapy resistance in melanoma
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errChurch, Isabella; Gruen, Charli; Sassano, Antonella; Valencia, Julio; Wu, Emily; Yang, Howard; Needle, Gabe; Smith, Cari; Chin, Sung; Ebersole, Jessica; Marcelus, Christina; Fon, Anyen; Liu, Huaitian; Day, Chi-Ping; Young, Howard; Lee, Maxwell; Merlino, Glenn; Perez-Guijarro, Eva
errShare
errSave
Systemic agonist anti-CD40 treatment delivers precise melanoma immunotherapy within established autoimmune landscapes
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errValencia, Julio C.; Sanford, Michael; Young, Howard A.
errShare
errSave
IL-4, IL-13 and IFN-γ-induced genes in highly purified human neutrophils
errCYTOKINE
IF3.7
err2023-04-01
err4
errOAAI
errKummola, Laura; Salomaa, Tanja; Ortutay, Zsuzsanna; Savan, Ram; Young, Howard A.; Junttila, Ilkka S.
errShare
errSave
Regulation of nuclear gamma interferon gene expression by interleukin 12 (IL-12) and IL-2 represents a novel form of posttranscriptional control
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err64
errOAAI
errHodge, DL; Martinez, A; Julias, JG; Taylor, LS; Young, HA
errShare
errSave
Infection with human immunodeficiency virus type 1 upregulates DNA methyltransferase, resulting in de novo methylation of the gamma interferon (IFN-γ) promoter and subsequent downregulation of IFN-γ production
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err155
errOAAI
errMikovits, JA; Young, HA; Vertino, P; Issa, JPJ; Pitha, PM; Turcoski-Corrales, S; Taub, DD; Petrow, CL; Baylin, SB; Ruscetti, FW
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Craig B. Thompson
H-index: 206 · Papers: 767
P
Peter Carmeliet
H-index: 192 · Papers: 1.4K
S
Stephen B. Baylin
H-index: 182 · Papers: 1.3K
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