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Volker Dötsch

goethe university of frankfurt

76H-index
541Paper Count
2.4WCitation Count
Published Papers 139
Publication Date
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Dynamic Hotspots in the Uba7 Ubiquitin-Fold Domain Direct UbcH8 Recognition
errBiochemistry
IF3
err2026-03-03
err0
PREAI
errÇağdaş Dağ; Mahil Lambert; Alp E. Kazar; Kerem Kahraman; Oktay Göcenler; Woonghee Lee; Cansu D. Tozkoparan Ceylan; Frank Löhr; Jin-Gon Shim; Arthur L. Haas; Volker Dötsch; Joshua Ziarek; Emine Sonay Elgin
errShare
errSave
Overcoming Ligand Discovery Challenges: Developing Peptide-Based Tracers for SPSB2
errACS CHEMICAL BIOLOGY
IF3.8
err2025-12-01
err0
PREAI
errLenz, Christopher; Elson, Lewis; Dopfer, Johannes; Farges, Frederic; Kramer, Andreas; Lohr, Frank; Muller, Susanne; Gueret, Stephanie M.; Waldmann, Herbert; Dotsch, Volker; Saxena, Krishna; Knapp, Stefan
errShare
errSave
Bacterial polyphosphates impede the macrophage response to infection
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errBosmann, Markus; Rowe, Julian; Brueck, Kevin; Jayaraman, Archana; Platten, Johannes; Krenzlin, Viola; Al-Janabi, Asala; Witzler, Claudius; Kaur, Dilraj; Lambert, Mahil; Raker, Verena K.; Muecklich, Sabrina; Mann, Amrit; Thati, Madhusudhan; Dotsch, Volker; Bloos, Frank; Bauer, Michael; Tenzer, Stefan; Reinhardt, Christoph; Malinarich, Frano
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errSave
p53 isoforms have a high aggregation propensity, interact with chaperones and lack binding to p53 interaction partners
errELIFE
IF0
err2025-09-10
err0
errOAAI
errBrdar, Anamari; Osterburg, Christian; Munick, Philipp; Machel, Anne Christin; Rathore, Rajeshwari; Osterburg, Susanne; Yuksel, Busra; Schafer, Birgit; Desch, Kristina; Langer, Julian D.; Dikic, Ivan; Dotsch, Volker
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errSave
Cryo-EM structure of a cell-free synthesized full-length human β1-adrenergic receptor in complex with Gs
errStructure
IF4.3
err2025-08-25
err0
errOAAI
errFelipe Merino; Zoe Köck; Utz Ermel; Philipp Dahlhaus; Anna Grimm; Anja Seybert; Jan Kubicek; Achilleas S. Frangakis; Volker Dötsch; Daniel Hilger; Frank Bernhard
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errSave
YTHDF proteins and m6A-RNA clients undergo autophagic turnover during contact inhibition
errCell Reports
IF6.9
err2025-08-23
err0
PREAI
errHung Ho-Xuan; Astrid Bruckmann; Lautaro Natali; Cristian Prieto-Garcia; Jan F.M. Stuke; Lorene Brunello; Alexandre Vicente; Alexander Pfab; Hagen Wesseling; Sara Cano-Franco; Anshu Khatri; Simone Larivera; Pablo Sanz-Martinez; Benjamin de la Cruz-Thea; Anne-Claire Jacomin; Jan Prochazka; Regina Feederle; Volker Dötsch; Radislav Sedlacek; Gerhard Hummer; Stefanie Kaiser; Ivan Dikic; Melina M. Musri; Gunter Meister; Alexandra Stolz
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errSave
A ribosome-associating chaperone mediates GTP-driven vectorial folding of nascent eEF1A
errNATURE COMMUNICATIONS
IF15.7
err2025-02-03
err0
errOAAI
errSabbarini, Ibrahim M.; Reif, Dvir; Park, Kibum; Mcquown, Alexander J.; Nelliat, Anjali R.; Trejtnar, Charlotte; Doetsch, Volker; Shakhnovich, Eugene I.; Murray, Andrew W.; Denic, Vladimir
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errSave
Alternative splicing in the DBD linker region of p63 modulates binding to DNA and iASPP in vitro
errCELL DEATH & DISEASE
IF9.6
err2025-01-06
err0
errOAAI
errLotz, Rebecca; Osterburg, Christian; Chaikuad, Apirat; Weber, Sabrina; Akutsu, Masato; Machel, Anne Christin; Beyer, Ulrike; Gebel, Jakob; Loehr, Frank; Knapp, Stefan; Dobbelstein, Matthias; Lu, Xin; Doetsch, Volker
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errSave
DARPins as a novel tool to detect and degrade p73
errCELL DEATH & DISEASE
IF9.6
err2024-12-18
err0
errOAAI
errMuenick, Philipp; Zielinski, Jasmin; Strubel, Alexander; Gutfreund, Niklas; Dreier, Birgit; Schaefer, Jonas V.; Schaefer, Birgit; Gebel, Jakob; Osterburg, Christian; Chaikuad, Apirat; Knapp, Stefan; Plueckthun, Andreas; Doetsch, Volker
errShare
errSave
Cardiocutaneous syndrome is caused by aggregation of iASPP mutants
errCELL DEATH DISCOVERY
IF7
err2024-12-18
err0
errOAAI
errLotz, Rebecca; Osterburg, Christian; Schaefer, Birgit; Lu, Xin; Doetsch, Volker
errShare
errSave
Characterizing the Monomer-Dimer Equilibrium of UbcH8/Ube2L6: A Combined SAXS and NMR Study
errACS OMEGA
IF4.3
err2024-09-09
err0
errOAAI
errKahraman, Kerem; Robson, Scott A.; Gocenler, Oktay; Yenici, Cansu M.; Ceylan, Cansu D. Tozkoparan; Klein, Jennifer M.; Dotsch, Volker; Elgin, Emine Sonay; Haas, Arthur L.; Ziarek, Joshua J.; Dag, Cagdas
errShare
errSave
Allosteric regulation of kinase activity
errELIFE
IF0
err2024-07-10
err0
errOAAI
errAndreotti, Amy H.; Doetsch, Volker
errShare
errSave
K48- and K63-linked ubiquitin chain interactome reveals branchand length-specific ubiquitin interactors
errLIFE SCIENCE ALLIANCE
IF2.9
err2024-05-21
err6
errOAAI
errWaltho, Anita; Popp, Oliver; Lenz, Christopher; Pluska, Lukas; Lambert, Mahil; Doetsch, Volker; Mertins, Philipp; Sommer, Thomas
errShare
errSave
Dichotomous transactivation domains contribute to growth inhibitory and promotion functions of TAp73
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-05-13
err0
errOAAI
errLi, Dan; Kok, Catherine Yen Li; Wang, Chao; Ray, Debleena; Osterburg, Susanne; Doetsch, Volker; Ghosh, Sujoy; Sabapathy, Kanaga
errShare
errSave
Narazaciclib's differential targets and kinase inhibitory activity contribute to the enhanced inhibition of tumor growth in preclinical models
errCANCER RESEARCH
IF16.6
err2024-05-02
err0
PREAI
errKechagioglou, Petros; Chakraborty, Debomita; Dupont, Camille; Yurugi, Hajime; Distler, Ute; Tenzer, Stefan; Chernobrovkin, Alexey; Riegel, Kristina; Mooz, Julianne; Lamber, Mahil; Dotsch, Volker; Cosenza, Stephen; Fruchtman, Steven; Rajalingam, Krishnaraj
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errSave
Cryo-EM structure of cell-free synthesized human histamine 2 receptor/Gs complex in nanodisc environment
errNATURE COMMUNICATIONS
IF15.7
err2024-02-28
err2
errOAAI
errKoeck, Zoe; Schnelle, Kilian; Persechino, Margherita; Umbach, Simon; Schihada, Hannes; Januliene, Dovile; Parey, Kristian; Pockes, Steffen; Kolb, Peter; Doetsch, Volker; Moeller, Arne; Hilger, Daniel; Bernhard, Frank
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errSave
The function of ER-phagy receptors is regulated through phosphorylation-dependent ubiquitination pathways
errNATURE COMMUNICATIONS
IF15.7
err2023-12-15
err11
errOAAI
errBerkane, Rayene; Ho-Xuan, Hung; Glogger, Marius; Sanz-Martinez, Pablo; Brunello, Lorene; Glaesner, Tristan; Kuncha, Santosh Kumar; Holzhueter, Katharina; Cano-Franco, Sara; Buonomo, Viviana; Cabrerizo-Poveda, Paloma; Balakrishnan, Ashwin; Tascher, Georg; Husnjak, Koraljka; Juretschke, Thomas; Misra, Mohit; Gonzalez, Alexis; Doetsch, Volker; Grumati, Paolo; Heilemann, Mike; Stolz, Alexandra
errShare
errSave
An atypical GABARAP binding module drives the pro-autophagic potential of the AML-associated NPM1c variant
errCELL REPORTS
IF6.9
err2023-12-01
err1
errOAAI
errMende, Hannah; Khatri, Anshu; Lange, Carolin; Poveda-Cuevas, Sergio Alejandro; Tascher, Georg; Covarrubias-Pinto, Adriana; Loehr, Frank; Koschade, Sebastian E.; Dikic, Ivan; Mu, Christian; Bremm, Anja; Brunetti, Lorenzo; Brandts, Christian H.; Uckelmann, Hannah; Doetsch, Volker; Rogov, Vladimir V.; Bhaskara, Ramachandra M.; Mueller, Stefan
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errSave
DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma
errCELL DEATH & DISEASE
IF9.6
err2023-10-12
err5
errOAAI
errStrubel, Alexander; Muenick, Philipp; Hartmann, Oliver; Chaikuad, Apirat; Dreier, Birgit; Schaefer, Jonas V.; Gebel, Jakob; Osterburg, Christian; Tuppi, Marcel; Schaefer, Birgit; Buck, Viktoria; Rosenfeldt, Mathias; Knapp, Stefan; Pluckthun, Andreas; Diefenbacher, Markus E.; Doetsch, Volker
errShare
errSave
Fuzzy interactions between the auto-phosphorylated C-terminus and the kinase domain of CK1δ inhibits activation of TAp63α
errSCIENTIFIC REPORTS
IF3.9
err2023-09-30
err4
errOAAI
errLambert, Mahil; Gebel, Jakob; Trejtnar, Charlotte; Wesch, Nicole; Bozkurt, Sueleyman; Adrian-Allgood, Martin; Loehr, Frank; Muench, Christian; Doetsch, Volker
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errSave

Research Directions

No research directions
Co-authors
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