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The Cambridge Centre for Myelin Repair trial Two (CCMR Two): a trial protocol for a phase 2a, randomised, double-blind, placebo-controlled clinical trial of the ability of the combination of metformin and clemastine to promote remyelination in people with relapsing-remitting multiple sclerosis already on disease-modifying therapy Riboni-Verri, Gioia; McMurran, Christopher E.; Mukherjee, Trisha; Daruwalla, Cyrus; Holland, Jonathon; Gautam, Riddhima; Chen, Benson S.; Cutting, Emma; Qian, Wendi; MacManus, David; Chard, Declan T.; Brown, J. William L.; Coles, Alasdair J.; Cunniffe, Nick G. Share Save
Single-centre, prospective cohort to predict optimal individualised treatment response in multiple sclerosis (POINT-MS): a cohort profile Christensen, Ronja; Cruciani, Alessandro; Al-Araji, Sarmad; Bianchi, Alessia; Chard, Declan; Fourali, Samih; Hamed, Weaam; Hammam, Ahmed; He, Anna; Kanber, Baris; Maccarrone, Davide; Moccia, Marcello; Mohamud, Suraya; Nistri, Riccardo; Passalis, Anestis; Pozzilli, Valeria; Prados Carrasco, Ferran; Samdanidou, Eirini; Song, Joy; Wingrove, Jed; Yam, Charmaine; Yiannakas, Marios; Thompson, Alan J.; Toosy, Ahmed; Hacohen, Yael; Barkhof, Frederik; Ciccarelli, Olga Share Save
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Exploratory analysis of biological age measures in a remyelination clinical trial Mcmurran, Christopher E.; de Meo, Ermelinda; Cunniffe, Nick G.; Brown, J. William L.; Prados, Ferran; Kanber, Baris; Cole, James H.; Coles, Alasdair J.; Hagg, Sara; Chard, Declan T. Share Save
An MRI assessment of mechanisms underlying lesion growth and shrinkage in multiple sclerosis De Meo, Ermelinda; Carrasco, Ferran Prados; Brown, J. William L.; Coles, Alasdair J.; Cunniffe, Nick G.; Jolly, Amy E.; Kanber, Baris; Samson, Rebecca; Barkhof, Frederik; Chard, Declan Share Save
Evaluating multiple sclerosis severity loci 30 years after a clinically isolated syndrome Sahi, Nitin; Haider, Lukas; Chung, Karen; Carrasco, Ferran Prados; Kanber, Baris; Samson, Rebecca; Thompson, Alan J.; Trip, S. Anand; Brownlee, Wallace; Ciccarelli, Olga; Barkhof, Frederik; Tur, Carmen; Houlden, Henry; Chard, Declan Share Save
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The influence of MOGAD on diagnosis of multiple sclerosis using MRI Geraldes, Ruth; Arrambide, Georgina; Banwell, Brenda; Rovira, Alex; Cortese, Rosa; Lassmann, Hans; Messina, Silvia; Rocca, Mara Assunta; Waters, Patrick; Chard, Declan; Gasperini, Claudio; Hacohen, Yael; Mariano, Romina; Paul, Friedemann; DeLuca, Gabriele C.; Enzinger, Christian; Kappos, Ludwig; Leite, M. Isabel; Sastre-Garriga, Jaume; Yousry, Tarek; Ciccarelli, Olga; Filippi, Massimo; Barkhof, Frederik; Palace, Jacqueline Share Save
Longitudinal network-based brain grey matter MRI measures are clinically relevant and sensitive to treatment effects in multiple sclerosis Colato, Elisa; Stutters, Jonathan; Narayanan, Sridar; Arnold, Douglas L.; Chataway, Jeremy; Wheeler-Kingshott, Claudia A. M. Gandini; Barkhof, Frederik; Ciccarelli, Olga; Eshaghi, Arman; Chard, Declan T. Share Save
The evolving contribution of MRI measures towards the prediction of secondary progressive multiple sclerosis Ananthavarathan, Piriyankan; Sahi, Nitin; Chung, Karen; Haider, Lukas; Prados, Ferran; Trip, S. Anand; Ciccarelli, Olga; Barkhof, Frederik; Tur, Carmen; Chard, Declan T. Share Save
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Genetic influences on disease course and severity, 30 years after a clinically isolated syndrome Sahi, Nitin; Haider, Lukas; Chung, Karen; Prados Carrasco, Ferran; Kanber, Baris; Samson, Rebecca; Thompson, Alan J.; Gandini Wheeler-Kingshott, Claudia A. M.; Trip, S. Anand; Brownlee, Wallace; Ciccarelli, Olga; Barkhof, Frederik; Tur, Carmen; Houlden, Henry; Chard, Declan Share Save
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Networks of microstructural damage predict disability in multiple sclerosis Colato, Elisa; Prados, Ferran; Stutters, Jonathan; Bianchi, Alessia; Narayanan, Sridar; Arnold, Douglas L.; Wheeler-Kingshott, Claudia; Barkhof, Frederik; Ciccarelli, Olga; Chard, Declan T.; Eshaghi, Arman Share Save
Multicenter Evaluation of AI-generated DIR and PSIR for Cortical and Juxtacortical Multiple Sclerosis Lesion Detection Bouman, Piet M.; Noteboom, Samantha; Santos, Fernando A. Nobrega; Beck, Erin S.; Bliault, Gregory; Castellaro, Marco; Calabrese, Massimiliano; Chard, Declan T.; Eichinger, Paul; Filippi, Massimo; Inglese, Matilde; Lapucci, Caterina; Marciniak, Andrzej; Moraal, Bastiaan; Pinzon, Alfredo Morales; Muehlau, Mark; Preziosa, Paolo; Reich, Daniel S.; Rocca, Maria A.; Schoonheim, MennoM.; Twisk, Jos W. R.; Wiestler, Benedict; Jonkman, Laura E.; Guttmann, Charles R. G.; Geurts, Jeroen J. G.; Steenwijk, Martijn D. Share Save
Relationship between paramagnetic rim lesions and slowly expanding lesions in multiple sclerosis Calvi, Alberto; Clarke, Margareta A.; Prados, Ferran; Chard, Declan; Ciccarelli, Olga; Alberich, Manel; Pareto, Deborah; Rodriguez Barranco, Marta; Sastre-Garriga, Jaume; Tur, Carmen; Rovira, Alex; Barkhof, Frederik Share Save
Remyelination varies between and within lesions in multiple sclerosis following bexarotene Brown, J. William L.; Prados, Ferran; Altmann, Daniel R.; Kanber, Baris; Stutters, Jonathan; Cunniffe, Nick G.; Jones, Joanne L.; Georgieva, Zoya G.; Needham, Edward J.; Daruwalla, Cyrus; Wheeler-Kingshott, Claudia Gandini; Connick, Peter; Chandran, Siddharthan; Franklin, Robin; MacManus, David; Samson, Rebecca; Coles, Alasdair; Chard, Declan Share Save
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