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Xiaoxiao Wan

Washington University School of Medicine

19H-index
124Paper Count
1.5KCitation Count
Published Papers 35
Publication Date
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From Disposal to Display: Crinophagy as a β-Cell Source of Neoantigens in Type 1 Diabetes
errImmunological Reviews
IF8.3
err2026-08-05
err0
PREAI
errAngela J. Zou; Xiaoxiao Wan
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From Damage Signals to Immune Modulators: Oxidized Lipids in Immunometabolic Inflammation
errJournal of Lipid Research
IF4.1
err2026-01-29
err0
errOAAI
errNeetu Srivastava; Xiaoxiao Wan
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errSave
A microenvironment-driven HLA-II-associated insulin neoantigen elicits persistent memory T cell activation in diabetes
errNature Immunology
IF27.6
err2025-11-28
err0
errOAAI
errNeetu Srivastava; Anthony N. Vomund; Rongzhen Yu; Orion J. Peterson; Yuqing Yang; David P. Turicek; Omar Abousaway; Tiandao Li; Lisa Kain; Pamela Stone; Aisha Ansar; Cristina C. Clement; Siddhartha Sharma; Rima Melhem; Bo Zhang; Chang Liu; Alok V. Joglekar; Hao Hu; Chyi-Song Hsieh; Laura Campisi; Laura Santambrogio; Luc Teyton; Emil R. Unanue; Ana Maria Arbelaez; Cheryl F. Lichti; Xiaoxiao Wan
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Efferocytic remodelling of pancreatic islet macrophages by limited β-cell death
errNature
IF48.5
err2025-10-01
err0
PREAI
errPavel N. Zakharov; Chanchal S. Chowdhury; Orion J. Peterson; Brady Barron; Anthony N. Vomund; Laurent Gorvel; Emil R. Unanue; Eynav Klechevsky; Xiaoxiao Wan; Kodi S. Ravichandran
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An interleukin-27-centered cytokine circuit regulates macrophage and T cell interactions in autoimmune diabetes
erriScience
IF4.1
err2025-09-10
err0
errOAAI
errAshley E. Ciecko; Rabia Nabi; Amber Drewek; David M. Schauder; Pavel N. Zakharov; Xiaoxiao Wan; Scott M. Lieberman; Weiguo Cui; Martin J. Hessner; Chien-Wei Lin; Yi-Guang Chen
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Decoding autoimmunity: HLA-DQβ and type 1 diabetes
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-04-28
err0
errOAAI
errTuricek, David P.; Wan, Xiaoxiao
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The epigenetic trajectory of type 1 regulatory T cells
errELIFE
IF0
err2024-11-14
err0
errOAAI
errTuricek, David P.; Wan, Xiaoxiao
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errSave
Crinophagic granules in pancreatic β cells contribute to mouse autoimmune diabetes by diversifying pathogenic epitope repertoire
errNATURE COMMUNICATIONS
IF15.7
err2024-09-27
err0
errOAAI
errHu, Hao; Vomund, Anthony N.; Peterson, Orion J.; Srivastava, Neetu; Li, Tiandao; Kain, Lisa; Beatty, Wandy L.; Zhang, Bo; Hsieh, Chyi-Song; Teyton, Luc; Lichti, Cheryl F.; Unanue, Emil R.; Wan, Xiaoxiao
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CXCL16-dependent scavenging of oxidized lipids by islet macrophages promotes differentiation of pathogenic CD8+T cells in diabetic autoimmunity
errIMMUNITY
IF26.3
err2024-07-01
err5
errOAAI
errSrivastava, Neetu; Hu, Hao; Peterson, Orion J.; Vomund, Anthony N.; Stremska, Marta; Zaman, Mohammad; Giri, Shilpi; Li, Tiandao; Lichti, Cheryl F.; Zakharov, Pavel N.; Zhang, Bo; Abumrad, Nada A.; Chen, Yi-Guang; Ravichandran, Kodi S.; Unanue, Emil R.; Wan, Xiaoxiao
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errSave
Role of the afferent lymph as an immunological conduit to analyze tissue antigenic and inflammatory load
errCELL REPORTS
IF6.9
err2024-06-01
err2
errOAAI
errNanaware, Padma P.; Khan, Zohaib N.; Clement, Cristina C.; Shetty, Madhur; Mota, Ines; Seltzer, Ethan S.; Dzieciatkowska, Monika; Gamboni, Fabia; D'Alessandro, Angelo; Ng, Charles; Nagayama, Manabu; Lichti, Cheryl F.; Soni, Rajesh K.; Geri, Jacob B.; Matei, Irina; Lyden, David; Longman, Randy; Lu, Theresa T.; Wan, Xiaoxiao; Unanue, Emil R.; Stern, Lawrence J.; Santambrogio, Laura
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The 162
errJOURNAL OF IMMUNOLOGY
IF3.4
err2024-05-01
err0
PREAI
errSrivastava, Neetu; Hu, Hao; Peterson, Orion; Vomund, Anthony; Stremska, Marta; Zaman, Mohammad; Giri, Shilpi; Li, Tiandao; Lichti, Cheryl; Zakharov, Pavel; Zhang, Bo; Abumrad, Nada; Chen, Yi-Guang; Ravichandran, Kodi; Unanue, Emil; Wan, Xiaoxiao
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Mapping of a hybrid insulin peptide in the inflamed islet β-cells from NOD mice
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-02-22
err2
errOAAI
errWenzlau, Janet M.; Peterson, Orion J.; Vomund, Anthony N.; Dilisio, James E.; Hohenstein, Anita; Haskins, Kathryn; Wan, Xiaoxiao
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errSave
Using mass spectrometry to identify neoantigens in autoimmune diseases: The type 1 diabetes example
errSEMINARS IN IMMUNOLOGY
IF7.8
err2023-03-01
err8
errOAAI
errLichti, Cheryl F.; Wan, Xiaoxiao
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errSave
Targeting Microglial Metabolic Rewiring Synergizes with Immune-Checkpoint Blockade Therapy for Glioblastoma
errCANCER DISCOVERY
IF33.3
err2023-01-17
err27
errOAAI
errYe, Zengpanpan; Ai, Xiaolin; Yang, Kailin; Yang, Zhengnan; Fei, Fan; Liao, Xiaoling; Qiu, Zhixin; Gimple, Ryan C.; Yuan, Huairui; Huang, Hao; Gong, Yanqiu; Xiao, Chaoxin; Yue, Jing; Huang, Liang; Saulnier, Olivier; Wang, Wei; Zhang, Peidong; Dai, Lunzhi; Wang, Xin; Wang, Xiuxing; Ha Ahn, Young; You, Chao; Xu, Jianguo; Wan, Xiaoxiao; Taylor, Michael D.; Zhao, Linjie; Rich, Jeremy N.; Zhou, Shengtao
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Chromogranin A Deficiency Confers Protection From Autoimmune Diabetes via Multiple Mechanisms
errDIABETES
IF7.5
err2021-09-08
err11
errOAAI
errSrivastava, Neetu; Hu, Hao; Vomund, Anthony N.; Peterson, Orion J.; Baker, Rocky L.; Haskins, Kathryn; Teyton, Luc; Wan, Xiaoxiao; Unanue, Emil R.
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Blood leukocytes recapitulate diabetogenic peptide-MHC-II complexes displayed in the pancreatic islets
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2021-04-06
err12
errOAAI
errVomund, Anthony N.; Lichti, Cheryl F.; Peterson, Orion J.; Arbelaez, Ana Maria; Wan, Xiaoxiao; Unanue, Emil R.
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Single-cell RNA sequencing of murine islets shows high cellular complexity at all stages of autoimmune diabetes
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2020-04-06
err92
errOAAI
errZakharov, Pavel N.; Hu, Hao; Wan, Xiaoxiao; Unanue, Emil R.
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errSave
The MHC-II peptidome of pancreatic islets identifies key features of autoimmune peptides (vol 21, pg 455, 2020)
errNATURE IMMUNOLOGY
IF27.6
err2020-04-01
err0
errOAAI
errWan, Xiaoxiao; Vomund, Anthony N.; Peterson, Orion J.; Chervonsky, Alexander V.; Lichti, Cheryl F.; Unanue, Emil R.
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errSave
The MHC-II peptidome of pancreatic islets identifies key features of autoimmune peptides
errNATURE IMMUNOLOGY
IF27.6
err2020-03-09
err63
errOAAI
errWan, Xiaoxiao; Vomund, Anthony N.; Peterson, Orion J.; Chervonsky, Alexander V.; Lichti, Cheryl F.; Unanue, Emil R.
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Position β57 of I-Ag7 controls early anti-insulin responses in NOD mice, linking an MHC susceptibility allele to type 1 diabetes onset
errSCIENCE IMMUNOLOGY
IF16.3
err2019-08-02
err44
errOAAI
errGioia, Louis; Holt, Marie; Costanzo, Anne; Sharma, Siddhartha; Abe, Brian; Kain, Lisa; Nakayama, Maki; Wan, Xiaoxiao; Su, Andrew; Mathews, Clayton; Chen, Yi-Guang; Unanue, Emil; Teyton, Luc
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Research Directions

No research directions
Co-authors
Cooperation Journals
M
Michael D. Taylor
H-index: 132 · Papers: 1.7K
J
Jeremy N. Rich
H-index: 127 · Papers: 1.5K
E
Emil R. Unanue
H-index: 118 · Papers: 585
A
Angelo D’Alessandro
H-index: 89 · Papers: 1.2K
K
Kodi S. Ravichandran
H-index: 88 · Papers: 310
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