Not logged inDifferential in vivo roles of Mpl cytoplasmic tyrosine residues in murine hematopoiesis and myeloproliferative disease
Behrens, Kira; Kauppi, Maria; Viney, Elizabeth M.; Kueh, Andrew J.; Hyland, Craig D.; Willson, Tracy A.; Salleh, Liam; de Graaf, Carolyn A.; Babon, Jeffrey J.; Herold, Marco J.; Nicola, Nicos A.; Alexander, Warren S. .png)
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SaveCryo-EM structure of the extracellular domain of murine Thrombopoietin Receptor in complex with ThrombopoietinSarson-Lawrence, Kaiseal T. G.; Hardy, Joshua M.; Iaria, Josephine; Stockwell, Dina; Behrens, Kira; Saiyed, Tamanna; Tan, Cyrus; Jebeli, Leila; Scott, Nichollas E.; Dite, Toby A.; Nicola, Nicos A.; Leis, Andrew P.; Babon, Jeffrey J.; Kershaw, Nadia J. Share Save Structure guided studies of the interaction between PTP1B and JAKMorris, Rhiannon; Keating, Narelle; Tan, Cyrus; Chen, Hao; Laktyushin, Artem; Saiyed, Tamanna; Liau, Nicholas P. D.; Nicola, Nicos A.; Tiganis, Tony; Kershaw, Nadia J.; Babon, Jeffrey J. Share Save The SOCS1 KIR and SH2 domain are both required for suppression of cytokine signaling in vivoDoggett, Karen; Keating, Narelle; Dehkhoda, Farhad; Bidgood, Grace M.; Guzman, Lizeth G. Meza; Leong, Evelyn; Kueh, Andrew; Nicola, Nicos A.; Kershaw, Nadia J.; Babon, Jeffrey J.; Alexander, Warren S.; Nicholson, Sandra E. Share Save Agm1/Pgm-3-mediated sugar nucleotide synthesis is essential for hematopoiesis and developmentGreig, Kylle T.; Antonchuk, Jennifer; Metcalf, Donald; Morgan, Phillip O.; Krebs, Danielle L.; Zhang, Jian-Guo; Hacking, Douglas F.; Bode, Lars; Robb, Lorraine; Kranz, Christian; de Graaf, Carolyn; Bahlo, Melanie; Nicola, Nicos A.; Nutt, Stephen L.; Freeze, Hudson H.; Alexander, Warren S.; Hilton, Douglas J.; Kile, Benjamin T. Share Save Share Save SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardationKrebs, DL; Uren, RT; Metcalf, D; Rakar, S; Zhang, JG; Starr, R; De Souza, DP; Hanzinikolas, K; Eyles, J; Connolly, LM; Simpson, RJ; Nicola, NA; Nicholson, SE; Baca, M; Hilton, DJ; Alexander, WS Share Save SOCS5 is expressed in primary B and T lymphoid cells but is dispensable for lymphocyte production and functionBrender, C; Columbus, R; Metcalf, D; Handman, E; Starr, R; Huntington, N; Tarlinton, D; Odum, N; Nicholson, SE; Nicola, NA; Hilton, DJ; Alexander, WS Share Save Share Save Proteomic analyses reveal that immune integrins are major targets for regulation by Membrane-Associated Ring-CH (MARCH) proteins MARCH2, 3, 4 and 9Sandow, Jarrod J.; Webb, Andrew I.; Stockwell, Dina; Kershaw, Nadia J.; Tan, Cyrus; Ishido, Satoshi; Alexander, Warren S.; Hilton, Douglas J.; Babon, Jeffrey J.; Nicola, Nicos A. Share Save RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cellsTullett, Kirsteen M.; Tan, Peck Szee; Park, Hae-Young; Schittenhelm, Ralf B.; Michael, Nicole; Li, Rong; Policheni, Antonia N.; Gruber, Emily; Huang, Cheng; Fulcher, Alex J.; Danne, Jillian C.; Czabotar, Peter E.; Wakim, Linda M.; Mintern, Justine D.; Ramm, Georg; Radford, Kristen J.; Caminschi, Irina; O'Keeffe, Meredith; Villadangos, Jose A.; Wright, Mark D.; Blewitt, Marnie E.; Heath, William R.; Shortman, Ken; Purcell, Anthony W.; Nicola, Nicos A.; Zhang, Jian-Guo; Lahoud, Mireille H. Share Save Membrane-associated RING-CH (MARCH) proteins down-regulate cell surface expression of the interleukin-6 receptor alpha chain (IL6Rα)Babon, Jeffrey J.; Stockwell, Dina; DiRago, Ladina; Zhang, Jian-Guo; Laktyushin, Artem; Villadangos, Jose; Ching, Alan; Ishido, Satoshi; Hilton, Douglas J.; Alexander, Warren S.; Nicola, Nicos A. Share Save RIPLET, and not TRIM25, is required for endogenous RIG-I-dependent antiviral responsesHayman, Thomas J.; Hsu, Alan C.; Kolesnik, Tatiana B.; Dagley, Laura F.; Willemsen, Joschka; Tate, Michelle D.; Baker, Paul J.; Kershaw, Nadia J.; Kedzierski, Lukasz; Webb, Andrew, I; Wark, Peter A.; Kedzierska, Katherine; Masters, Seth L.; Belz, Gabrielle T.; Binder, Marco; Hansbro, Philip M.; Nicola, Nicos A.; Nicholson, Sandra E. Share Save The molecular basis of JAK/STAT inhibition by SOCS1Liau, Nicholas P. D.; Laktyushin, Artem; Lucet, Isabelle S.; Murphy, James M.; Yao, Shenggen; Whitlock, Eden; Callaghan, Kimberley; Nicola, Nicos A.; Kershaw, Nadia J.; Babon, Jeffrey J. Share Save Identification of a second binding site on the TRIM25 B30.2 domainD'Cruz, Akshay A.; Kershaw, Nadia J.; Hayman, Thomas J.; Linossi, Edmond M.; Chiang, Jessica J.; Wang, May K.; Dagley, Laura F.; Kolesnik, Tatiana B.; Zhang, Jian-Guo; Masters, Seth L.; Griffin, Michael D. W.; Gack, Michaela U.; Murphy, James M.; Nicola, Nicos A.; Babon, Jeffrey J.; Nicholson, Sandra E. Share Save Share Save Suppressor of cytokine signaling (SOCS)5 ameliorates influenza infection via inhibition of EGFR signalingKedzierski, Lukasz; Tate, Michelle D.; Hsu, Alan C.; Kolesnik, Tatiana B.; Linossi, Edmond M.; Dagley, Laura; Dong, Zhaoguang; Freeman, Sarah; Infusini, Giuseppe; Starkey, Malcolm R.; Bird, Nicola L.; Chatfield, Simon M.; Babon, Jeffrey J.; Huntington, Nicholas; Belz, Gabrielle; webb, Andrew; Wark, Peter A. B.; Nicola, Nicos A.; Xu, Jianqing; Kedzierska, Katherine; Hansbro, Philip M.; Nicholson, Sandra E. Share Save Murine Oncostatin M Acts via Leukemia Inhibitory Factor Receptor to Phosphorylate Signal Transducer and Activator of Transcription 3 (STAT3) but Not STAT1, an Effect That Protects Bone MassWalker, Emma C.; Johnson, Rachelle W.; Hu, Yifang; Brennan, Holly J.; Poulton, Ingrid J.; Zhang, Jian-Guo; Jenkins, Brendan J.; Smyth, Gordon K.; Nicola, Nicos A.; Sims, Natalie A. Share Save Share Save Share Save 
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