Ralph A. DeFronzo - Publications, H-index & Citations

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Ralph A. DeFronzo

University of Texas Health San Antonio

98H-index

410Paper Count

5.2WCitation Count

Published Papers 166

Publication Date

Association of Ultra-Processed Food Intake with Insulin Secretion and Sensitivity in Mexican American Children: Results from the SAFARI Study

Nutrients

IF5

2026-08-11

OAAI

Hemant Kulkarni; Rector Arya; Srinivas Mummidi; Sharon P. Fowler; Roy G. Resendez; Juan Carlos Lopez-Alvarenga; Alvaro Diaz-Badillo; Jennifer Schneider; Sobha Puppala; Vidya Farook; Daniel E. Hale; Jane L. Lynch; Bradley C. Johnston; Vijay Golla; Donna M. Lehman; Ralph A. DeFronzo; John Blangero; Ravindranath Duggirala

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Methodological and Conceptual Concerns Regarding the 24-h Glycaemia/C-Peptide Ratio as a Novel Insulin Sensitivity Index

DIABETES OBESITY & METABOLISM

IF5.7

2026-08-06

PREAI

Hussein Zaitoon; Marzieh Salehi; Ralph A. DeFronzo

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How the First 9 Months Shape the Rest of Your Life: The Impact of Gestational Diabetes on the Metabolic Future

DIABETES OBESITY & METABOLISM

IF5.7

2026-08-05

OAAI

Mustafa Kanat; Muhammad Abdul-Ghani; Ralph A. DeFronzo

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Insulin Sensitive Patients With Impaired Glucose Tolerance: Physiologic and Metabolic Characterization (STOP DIABETES)

diabetes, obesity and metabolism

IF0

2026-04-13

PREAI

John Armato; Ralph A. DeFronzo; Muhammad Abdul-Ghani; Ron Ruby

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Insulin resistance and hyperinsulinaemia in kidney disease: mechanisms and metabolic effects

Nature Reviews Nephrology

IF39.8

2026-03-25

PREAI

Hussein Zaitoon; Muhammad Abdul-Ghani; Ralph A. DeFronzo

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Chronically elevated sympathetic nervous system tone: A significant, common, and poorly realised contributor to cardiometabolic disease in type 2 diabetes

Diabetes, Obesity and Metabolism

IF0

2025-12-15

OAAI

Ralph A. DeFronzo MD

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Impact of pulmonary hypertension on short and long-term outcome after mitral transcatheter edge-to-edge repair: A meta-analysis

CARDIOVASCULAR REVASCULARIZATION MEDICINE

IF0

2025-09-01

PREAI

Neppala, Sivaram; Chigurupati, Himaja Dutt; Fath, Ayman; Jagirdhar, Gowthami Sai Kogilathota; Sandhyavenu, Harigopal; Bolte, Jeffery; Muhammad, Abdullah Naveed; Sattar, Yasar; Desai, Rupak; Defronzo, Ralph A.; Paul, Timir K.; Prasad, Anand

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Glycemic and non-glycemic benefits of initial triple therapy versus sequential add-on therapy in patients with new-onset diabetes: results from the EDICT study

BMJ OPEN DIABETES RESEARCH & CARE

IF4.1

2025-04-27

OAAI

Abdul-Ghani, Muhammad; Puckett, Curtiss; Abdelgani, Siham; Merovci, Aurora; Lavrynenko, Olga; Adams, John; Triplitt, Curtis; Defronzo, Ralph A.

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Mesenteric Visceral Lipectomy Improves Glucose Tolerance in Patients With Type 2 Diabetes: A Pilot Study

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

IF5.1

2024-12-17

OAAI

Baskoy, Gozde; Peterson, Richard M.; Kempenich, Jason; Triplitt, Curtis; Brown, Marissa; Clarke, Geoffrey D.; Cersosimo, Eugenio; Andrew, Mark S.; Lavrynenko, Olga; Chavez-Velazquez, Alberto O.; Hansis-Diarte, Andrea; Salehi, Marzieh; Defronzo, Ralph A.

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Effect of dapagliflozin on renal haemodynamics in hyperfiltering T2D patients

DIABETES OBESITY & METABOLISM

IF5.7

2024-11-27

PREAI

Cersosimo, Eugenio; YueJuan, Qin; Baskoy, Gozde; Chavez, Alberto; Barkhordarian, Maryam; Hansis-Diarte, Andrea; Triplitt, Curtis; DeFronzo, Ralph A.

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Effect of weight-maintaining ketogenic diet on glycemic control and insulin sensitivity in obese T2D subjects

BMJ OPEN DIABETES RESEARCH & CARE

IF4.1

2024-10-18

OAAI

Merovci, Aurora; Finley, Brittany; Hansis-Diarte, Andrea; Neppala, Sivaram; Abdul-Ghani, Muhammad A.; Cersosimo, Eugenio; Triplitt, Curtis; DeFronzo, Ralph A.

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Advances and counterpoints in type 2 diabetes. What is ready for translation into real-world practice, ahead of the guidelines

BMC MEDICINE

IF8.3

2024-09-04

OAAI

Schwartz, Stanley S.; Corkey, Barbara E.; Gavin, James R.; DeFronzo, Ralph A.; Herman, Mary E.

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Insulin sensitivity and beta cell function after duodenal mucosal resurfacing: an open-label, mechanistic, pilot study

GASTROINTESTINAL ENDOSCOPY

IF7.5

2024-09-01

OAAI

Busch, Celine B. E.; Meiring, Suzanne; van Baar, Annieke C. G.; Gastaldelli, Amalia; DeFronzo, Ralph; Mingrone, Geltrude; Hagen, Moira; White, Kelly; Rajagopalan, Harith; Nieuwdorp, Max; Bergman, Jacques J. G. H. M.

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Unexplained Residual Risk In Type 2 Diabetes: How Big Is The Problem?

CURRENT CARDIOLOGY REPORTS

IF3.3

2024-04-18

PREAI

Neppala, Sivaram; Rajan, Jemema; Yang, Eric; DeFronzo, Ralph A.

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The impact of increased hepatic glucose production caused by empagliflozin on plasma glucose concentration in individuals with type 2 diabetes and nondiabetic individuals

DIABETES OBESITY & METABOLISM

IF5.7

2023-12-22

PREAI

Abdelgani, Siham; Khattab, Ahmed; Adams, John; Baskoy, Gozde; Triplitt, Curtis; Defronzo, Ralph A.; Abdul-Ghani, Muhammad

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Emergence of a New Glucoregulatory Mechanism for Glycemic Control With Dapagliflozin/Exenatide Therapy in Type 2 Diabetes

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

IF5.1

2023-07-22

PREAI

Cersosimo, Eugenio; Alatrach, Mariam; Solis-Herrera, Carolina; Baskoy, Gozde; Adams, John; Hansis-Diarte, Andrea; Gastaldelli, Amalia; Chavez, Alberto; Triplitt, Curtis; DeFronzo, Ralph A.

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Peripheral disruption of the grb10 gene enhances insulin signaling and sensitivity in vivo

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

132

OAAI

Wang, Lixin; Balas, Bogdan; Christ-Roberts, Christine Y.; Kim, Ryang Yeo; Ramos, Fresnida J.; Kikani, Chintan K.; Li, Cuiling; Deng, Chuxia; Reyna, Sara; Musi, Nicolas; Dong, Lily Q.; DeFronzo, Ralph A.; Liu, Feng

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Fasting Hyperinsulinemia and Obesity: Cause or Effect

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

IF5.1

2023-03-22

PREAI

Abdul-Ghani, Muhammad; DeFronzo, Ralph A.

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Distinct Mechanisms Responsible for the Increase in Glucose Production and Ketone Formation Caused by Empagliflozin in T2DM Patients

DIABETES CARE

IF16.6

2023-03-01

OAAI

Abdelgani, Siham; Khattab, Ahmed; Adams, John; Abu-Farha, Mohamed; Daniele, Guisepe; Al-Mulla, Fahd; Del Prato, Stefano; DeFronzo, Ralph A.; Abdul-Ghani, Muhammad

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Pioglitazone reduces epicardial fat and improves diastolic function in patients with type 2 diabetes

DIABETES OBESITY & METABOLISM

IF5.7

2022-11-04

OAAI

Moody, Alexander J.; Molina-Wilkins, Marjorie; Clarke, Geoffrey D.; Merovci, Aurora; Solis-Herrera, Carolina; Cersosimo, Eugenio; Chilton, Robert J.; Iozzo, Patricia; Gastaldelli, Amalia; Abdul-Ghani, Muhammad; DeFronzo, Ralph A.

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Research Directions