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Pharmacological increases in circulating ketones fail to alleviate the hypertrophic cardiomyopathy present in the Tafazzin knockdown mouse model of Barth syndrome Shafaati, Tanin; Greenwell, Amanda A.; Saed, Christina T.; Tabatabaei Dakhili, Seyed Amirhossein; Chan, Jordan S. F.; Dong, Linyue; Stenlund, Magnus J.; Ferrari, Sally R.; Han, Ruth; Kruger, Jennifer; Eaton, Farah; Gopal, Keshav; Davidge, Sandra T.; Oudit, Gavin Y.; Ussher, John R. Share Save
Metformin alleviates diastolic dysfunction in mice with experimental diabetic cardiomyopathy Chan, Jordan S. F.; Dakhili, Seyed Amirhossein Tabatabaei; Wu, Nadeen R.; Stenlund, Magnus J.; King, Alexa N.; Dong, Linyue; Mangra-Bala, Indiresh A.; Shafaati, Tanin; Ferrari, Sally R.; Greenwell, Amanda A.; Yang, Kunyan; Saed, Christina T.; Eaton, Farah; Gopal, Keshav; Steinberg, Gregory R.; Dyck, Jason R. B.; Ussher, John R. Share Save
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Development of a succinyl CoA:3-ketoacid CoA transferase inhibitor selective for peripheral tissues that improves glycemia in obesity Dakhili, Seyed Amirhossein Tabatabaei; Yang, Kunyan; Al Nebaihi, Hamdah; Greenwell, Amanda A.; Wuest, Melinda; Woodfield, Jenilee; Abou Farraj, Rabih; Saed, Christina T.; Chan, Jordan S. F.; Bhat, Rakesh K.; Mangra-Bala, Indiresh A.; Shafaati, Tanin; Gopal, Keshav; Eaton, Farah; Ferrari, Sally R.; Wagg, Cory S.; Capozzi, Megan E.; Campbell, Jonathan E.; Overduin, Michael; Velazquez-Martinez, Carlos A.; Glover, J. N. Mark; Wuest, Frank; Brocks, Dion R. Share Save
Growth differentiation factor 15 alleviates diastolic dysfunction in mice with experimental diabetic cardiomyopathy Chan, Jordan S. F.; Dakhili, Seyed Amirhossein Tabatabaei; Lorenzana-Carrillo, Maria Areli; Gopal, Keshav; Pulente, Serena M.; Greenwell, Amanda A.; Yang, Kunyan; Saed, Christina T.; Stenlund, Magnus J.; Ferrari, Sally R.; Mangra-Bala, Indiresh A.; Shafaati, Tanin; Bhat, Rakesh K.; Eaton, Farah; Overduin, Michael; Jorgensen, Sebastian Beck; Steinberg, Gregory R.; Mulvihill, Erin E.; Sutendra, Gopinath; Ussher, John R. Share Save
Liraglutide alleviates experimental diabetic cardiomyopathy in a PDH-dependent manner Chan, Jordan S. F.; Greenwell, Amanda A.; Saed, Christina T.; Stenlund, Magnus J.; Mangra-Bala, Indiresh A.; Dakhili, Seyed Amirhossein Tabatabaei; Yang, Kunyan; Ferrari, Sally R.; Eaton, Farah; Gopal, Keshav; Ussher, John R. Share Save
Pharmacological Inhibition of Succinyl Coenzyme A:3-Ketoacid Coenzyme A Transferase Alleviates the Progression of Diabetic Cardiomyopathy Greenwell, Amanda A.; Tabatabaei Dakhili, Seyed Amirhossein; Wagg, Cory S.; Saed, Christina T.; Chan, Jordan S. F.; Yang, Kunyan; Mangra-Bala, Indiresh A.; Stenlund, Magnus J.; Eaton, Farah; Gopal, Keshav; Dyck, Jason R. B.; Lopaschuk, Gary D.; Ussher, John R. Share Save
Loss of muscle PDH induces lactic acidosis and adaptive anaplerotic compensation via pyruvate-alanine cycling and glutaminolysis Gopal, Keshav; Abdualkader, Abdualrahman Mohammed; Li, Xiaobei; Greenwell, Amanda A.; Karwi, Qutuba G.; Altamimi, Tariq R.; Saed, Christina; Uddin, Golam M.; Darwesh, Ahmed M.; Jamieson, K. Lockhart; Kim, Ryekjang; Eaton, Farah; Seubert, John M.; Lopaschuk, Gary D.; Ussher, John R.; Batran, Rami Al Share Save
Ketone ester administration improves glycemia in obese mice Dakhili, Seyed Amirhossein Tabatabaei; Yang, Kunyan; Locatelli, Cassandra A. A.; Saed, Christina T.; Greenwell, Amanda A.; Chan, Jordan S. F.; Chahade, Jadin J.; Scharff, Jared; Al-Imarah, Shahad; Eaton, Farah; Crawford, Peter A.; Gopal, Keshav; Mulvihill, Erin E.; Ussher, John R. Share Save
Elucidating the sex differences in a translational mouse model of diabetic cardiomyopathy Gopal, Keshav; Saed, Christina; Chan, Jordan; Dimaano, Toni; Benyaminov, Faina; Greenwell, Amanda; Dakhili, Seyed Amirhossein Tabatabaei; Eaton, Farah; Al Batran, Rami; Ussher, John Share Save
TRIM35-mediated degradation of nuclear PKM2 destabilizes GATA4/6 and induces P53 in cardiomyocytes to promote heart failure Lorenzana-Carrillo, Maria Areli; Gopal, Keshav; Byrne, Nikole J.; Tejay, Saymon; Saleme, Bruno; Das, Subhash K.; Zhang, Yongneng; Haromy, Alois; Eaton, Farah; Pla, Michelle Mendiola; Bowles, Dawn E.; Dyck, Jason R. B.; Ussher, John R.; Michelakis, Evangelos D.; Sutendra, Gopinath Share Save
The Antipsychotic Dopamine 2 Receptor Antagonist Diphenylbutylpiperidines Improve Glycemia in Experimental Obesity by Inhibiting Succinyl-CoA:3-Ketoacid CoA Transferase Dakhili, Seyed Amirhossein Tabatabaei; Greenwell, Amanda A.; Yang, Kunyan; Abou Farraj, Rabih; Saed, Christina T.; Gopal, Keshav; Chan, Jordan S. F.; Chahade, Jadin J.; Eaton, Farah; Lee, Crystal; Velazquez-Martinez, Carlos A.; Crawford, Peter A.; Glover, J. N. Mark; Al Batran, Rami; Ussher, John R. Share Save
Pulmonary and Neurologic Effects of Mesenchymal Stromal Cell Extracellular Vesicles in a Multifactorial Lung Injury Model Lithopoulos, Marissa A.; Strueby, Lannae; O'Reilly, Megan; Zhong, Shumei; Mobius, Marius A.; Eaton, Farah; Fung, Moses; Hurskainen, Maria; Cyr-Depauw, Chanele; Suen, Colin; Xu, Liqun; Collins, Jennifer J. P.; Vadivel, Arul; Stewart, Duncan J.; Burger, Dylan; Thebaud, Bernard Share Save
FoxO1 inhibition alleviates type 2 diabetes-related diastolic dysfunction by increasing myocardial pyruvate dehydrogenase activity Gopal, Keshav; Al Batran, Rami; Altamimi, Tariq R.; Greenwell, Amanda A.; Saed, Christina T.; Dakhili, Seyed Amirhossein Tabatabaei; Dimaano, M. Toni E.; Zhang, Yongneng; Eaton, Farah; Sutendra, Gopinath; Ussher, John R. Share Save
Neural crest-specific loss of Bmp7 leads to midfacial hypoplasia, nasal airway obstruction and disordered breathing, modeling obstructive sleep apnea Baddam, Pranidhi; Biancardi, Vivian; Roth, Daniela M.; Eaton, Farah; Thereza-Bussolaro, Claudine; Mandal, Rupasri; Wishart, David S.; Barr, Amy; MacLean, Joanna; Flores-Mir, Carlos; Pagliardini, Silvia; Graf, Daniel Share Save
The GLP-1 Receptor Agonist Liraglutide Increases Myocardial Glucose Oxidation Rates via Indirect Mechanisms and Mitigates Experimental Diabetic Cardiomyopathy Almutairi, Malak; Gopal, Keshav; Greenwell, Amanda A.; Young, Adrian; Gill, Robert; Aburasayn, Hanin; Al Batran, Rami; Chahade, Jadin J.; Gandhi, Manoj; Eaton, Farah; Mailloux, Ryan J.; Ussher, John R. Share Save
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Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation Al Batran, Rami; Gopal, Keshav; Capozzi, Megan E.; Chahade, Jadin J.; Saleme, Bruno; Tabatabaei-Dakhili, S. Amirhossein; Greenwell, Amanda A.; Niu, Jingjing; Almutairi, Malak; Byrne, Nikole J.; Masson, Grant; Kim, Ryekjang; Eaton, Farah; Mulvihill, Erin E.; Garneau, Lea; Masters, Andrea R.; Desta, Zeruesenay; Velazquez-Martinez, Carlos A.; Aguer, Celine; Crawford, Peter A.; Sutendra, Gopinath; Campbell, Jonathan E.; Dyck, Jason R. B.; Ussher, John R. Share Save
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