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SaveBivalent SMAC mimetic APG-1387 reduces HIV reservoirs and limits viral rebound in humanized mice
Jain, Jaspreet; Pham, Tram N. Q.; Begum, Sharmin; Romero-Medina, Maria Carmen; Bellini, Nicolas; Li, Yuanyi; Dallaire, Frederic; Beland, Kathie; Patey, Natasha; Guimond, Jean, V; Haddad, Elle; Zhai, Yifan; Cohen, Eric A.
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SaveOncogenic human papillomavirus hijacks p300 to drive viral transcription, creating a therapeutic vulnerability that can be exploited with selective p300/CBP catalytic inhibitors
Kobylarz, M.; Larke, M.; Glore, W.; Shum, M.; Mori, K.; Cohen, E.; Pandey, A.; Hopkins, T.; McKeown, M.; Obholzer, N.; Trotter, B.; Carvajal, L.; Rahl, P.; Lin, C.
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SaveNear full-length HIV sequencing in multiple tissues collected postmortem reveals shared clonal expansions across distinct reservoirs during ART
Dufour, Caroline; Ruiz, Maria Julia; Pagliuzza, Amelie; Richard, Corentin; Shahid, Aniqa; Fromentin, Remi; Ponte, Rosalie; Cattin, Amelie; Salinas, Tomas Raul Wiche; Salahuddin, Syim; Sandstrom, Teslin; Schinkel, Stephanie Burke; Costiniuk, Cecilia T.; Jenabian, Mohammad-Ali; Ancuta, Petronela; Routy, Jean-Pierre; Cohen, Eric A.; Brumme, Zabrina L.; Power, Christopher; Angel, Jonathan B.; Chomont, Nicolas
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SaveRNA trafficking signals in human immunodeficiency virus type 1
Mouland, AJ; Xu, HB; Cui, HY; Krueger, W; Munro, TP; Prasol, M; Mercier, J; Rekosh, D; Smith, R; Barbarese, E; Cohen, EA; Carson, JH
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SaveNeuroinflammation-Induced Interactions between Protease-Activated Receptor 1 and Proprotein Convertases in HIV-Associated Neurocognitive Disorder
Kim, WooJin; Zekas, Erin; Lodge, Robert; Susan-Resiga, Delia; Marcinkiewicz, Edwidge; Essalmani, Rachid; Mihara, Koichiro; Ramachandran, Rithwik; Asahchop, Eugene; Gelman, Benjamin; Cohen, Eric A.; Power, Christopher; Hollenberg, Morley D.; Seidah, Nabil G.
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SaveGeneration of functional human T cell development in NOD/SCID/IL2rgnull humanized mice without using fetal tissue: Application as a model of HIV infection and persistence
Colas, Chloe; Volodina, Olga; Beland, Kathie; Pham, Tram N. Q.; Li, Yuanyi; Dallaire, Frederic; Soulard, Clara; Lemieux, William; Colamartino, Aurelien B. L.; Tremblay-Laganiere, Camille; Dicaire, Renee; Guimond, Jean; Vobecky, Suzanne; Poirier, Nancy; Patey, Natasha; Cohen, Eric A.; Haddad, Elie
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SaveSKI-1/S1P Facilitates SARS-CoV-2 Spike Induced Cell-to-Cell Fusion via Activation of SREBP-2 and Metalloproteases, Whereas PCSK9 Enhances the Degradation of ACE2
Essalmani, Rachid; Andreo, Ursula; Evagelidis, Alexandra; Le Devehat, Mailys; Ramos, Oscar Henrique Pereira; Gaillard, Carole Fruchart; Susan-Resiga, Delia; Cohen, Eric A.; Seidah, Nabil G.
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SaveDistinctive Roles of Furin and TMPRSS2 in SARS-CoV-2 Infectivity (vol 96, e00128-22, 2022)
Essalmani, Rachid; Jain, Jaspreet; Susan-Resiga, Delia; Andreo, Ursula; Evagelidis, Alexandra; Derbali, Rabeb Mouna; Huynh, David N.; Dallaire, Frederic; Laporte, Melanie; Delpal, Adrien; Sutto-Ortiz, Priscila; Coutard, Bruno; Mapa, Claudine; Wilcoxen, Keith; Decroly, Etienne; Pham, Tram N. Q.; Cohen, Eric A.; Seidah, Nabil G.
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SaveDistinctive Roles of Furin and TMPRSS2 in SARS-CoV-2 Infectivity
Essalmani, Rachid; Jain, Jaspreet; Susan-Resiga, Delia; Andreo, Ursula; Evagelidis, Alexandra; Derbali, Rabeb Mouna; Huynh, David N.; Dallaire, Frederic; Laporte, Melanie; Delpal, Adrien; Sutto-Ortiz, Priscila; Coutard, Bruno; Mapa, Claudine; Wilcoxen, Keith; Decroly, Etienne; Nq Pham, Tram; Cohen, Eric A.; Seidah, Nabil G.
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SaveLentiviral Infections Persist in Brain despite Effective Antiretroviral Therapy and Neuroimmune Activation
Mohammadzadeh, Nazanin; Roda, Weston; Branton, William G.; Clain, Julien; Rabezanahary, Henintsoa; Zghidi-Abouzid, Ouafa; Gelman, Benjamin B.; Angel, Jonathan B.; Cohen, Eric A.; Gill, M. John; Li, Michael; Estaquier, Jerome; Power, Christopher
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