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E

Edmund V. Capparelli

duke university

63H-index
386Paper Count
1.5WCitation Count
Published Papers 149
Publication Date
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VRC01 with antiretroviral initiation in infants is well tolerated; and higher concentrations associate with greater HIV-1 DNA declines
errScience Translational Medicine
IF14.6
err2026-05-06
err0
PREAI
errAlka Khaitan; Jane C. Lindsey; Edmund V. Capparelli; Camlin Tierney; Anne Coletti; Charlotte Perlowski; Dwight E. Yin; Mary Elizabeth (Betsy) Smith; Hans M. L. Spiegel; Sai Majji; Jack Moye; Lucio Gama; Richard A. Koup; Bob C. Lin; Adrian B. McDermott; Lynette Purdue; Chelsea Krotje; Paul A. Harding; Mark F. Cotton; Diane Costello; Christos J. Petropoulos; Jacqueline D. Reeves; Macpherson Mallewa; Rachel Chihana; Portia Kamthunzi; Tapiwa G. Mbengeranwa; Gaerolwe Masheto; Maria Letícia Santos Cruz; Jose Henrique Pilotto; Ponego L. Ponatshego; Deborah Persaud; Elizabeth J. McFarland;
errShare
errSave
Population Pharmacokinetics to Support Intravenous and Enteral Methadone Dosing in Children
errJournal of Clinical Pharmacology
IF2.3
err2026-01-01
err0
errOAAI
errWatt, Kevin M.; Thompson, Elizabeth J.; Lam, Lisa; Zimmerman, Kanecia; Hornik, Christoph P.; Atz, Andrew M.; Fernandez, Allison; Hupp, Susan R.; Bhatt-mehta, Varsha; Benjamin, Daniel K.; Anand, Ravinder; Cohen-wolkowiez, Michael; Gonzalez, Daniel; Smith, P. Brian; Capparelli, Edmund V.
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errSave
Safety and pharmacokinetics of dolutegravir dispersible tablets and oral films in term neonates exposed to HIV in South Africa (PETITE-DTG study): an open-label, randomised, phase 1/2 trial
errThe Lancet HIV
IF0
err2025-10-08
err0
PREAI
errAdrie Bekker; Nicolas Salvadori; Helena Rabie; Samantha du Toit; Kanchana Than-in-at; Maria Groenewald; Shaun Barnabas; Lindee Ganger; Thanchanok Luangcharoenkul; Sirikanya Pingkarawat; Edmund V Capparelli; Andrew Owen; Ratchada Cressey; Samantha Fry; Geraldine Le Roux; Yardpiroon Tawon; Jutatip Kaewmalee; Thamonphat Phitak; Marc Lallemant; Mark F Cotton; Tim R Cressey
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errSave
ART-free HIV-1 remission in children with in-utero HIV-1 after very early ART (IMPAACT P1115): a multicentre, open-label, phase 1/2 proof-of-concept study
errThe Lancet HIV
IF0
err2025-09-25
err0
PREAI
errDeborah Persaud; Anne Coletti; Bryan S Nelson; Jennifer Jao; Edmund V Capparelli; Diane Costello; Camlin Tierney; Adeodata R Kekitiinwa; Teacler Nematadzira; Boniface N Njau; John Moye; Patrick Jean-Philippe; Violet Korutaro; Annet Nalugo; Tapiwa Mbengeranwa; Tinashe Chidemo; Blandina T Mmbaga; Philoteus A Sakasaka; Mark Cotton; Cheryl Jennings; Carly Hoffmann; Laura Hovind; Yvonne Bryson; Ellen G Chadwick
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GS-443902 concentrations in peripheral blood mononuclear cells and dried blood spots among pregnant and non-pregnant women receiving remdesivir for COVID-19 treatment
errBritish Journal of Clinical Pharmacology
IF3
err2025-09-03
err0
errOAAI
errA. Dunbar; K. Baltrusaitis; D. Clarke; S. Nachman; K. Powis; A. Stek; A. Eke; D. Shapiro; E. Capparelli; F. Bone; E. Greene; K. George; D. Yin; P. Jean-Philippe; N. Chakhtoura; K. Kersey; L. Bushman; L. Roon; B. Best; M. Mirochnick; J. Momper; K. Brooks
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Variability in Meropenem Distribution and Clearance in Children with Sepsis: Population-Based Pharmacokinetics with Assessment of Renal Biomarkers
errCLINICAL PHARMACOKINETICS
IF4
err2025-04-24
err0
errOAAI
errLe, Jennifer; Huynh, Julie; Vo, Brandon; Mai, Annie; Mak, Robert H.; Momper, Jeremiah D.; Capparelli, Edmund V.; Harvey, Helen; Avedissian, Sean; Bradley, Erin; Sitapati, Amy; Singh, Karandeep; Bradley, John S.
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errSave
Virologic effects of broadly neutralizing antibodies VRC01LS and VRC07-523LS on chronic HIV-1 infection
errJCI INSIGHT
IF6.1
err2025-02-24
err0
errOAAI
errHappe, Myra; Lynch, Rebecca M.; Fichtenbaum, Carl J.; Heath, Sonya L.; Koletar, Susan L.; Landovitz, Raphael J.; Presti, Rachel M.; Santana-Bagur, Jorge L.; Tressler, Randall L.; Holman, LaSonji A.; Novik, Laura; Roa, Jhoanna C.; Rothwell, Ro Shauna; Strom, Larisa; Wang, Jing; Hu, Zonghui; Conan-Cibotti, Michelle; Bhatnagar, Anjali M.; Dwyer, Bridget; Ko, Sung Hee; Belinky, Frida; Namboodiri, Aryan M.; Pandey, Janardan P.; Carroll, Robin; Basappa, Manjula; Serebryannyy, Leonid; Narpala, Sandeep R.; Lin, Bob C.; Mcdermott, Adrian B.; Boritz, Eli A.; Capparelli, Edmund V.; Coates, Emily E.; Koup, Richard A.; Ledgerwood, Julie E.; Mascola, John R.; Chen, Grace L.; Tebas, Pablo
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Safety, Tolerability, and Pharmacokinetics of Long-Acting Broadly Neutralizing HIV-1 Monoclonal Antibody VRC07-523LS in Newborn Infants Exposed to HIV-1
errJOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY
IF2.6
err2025-01-16
err0
PREAI
errCunningham, Coleen K.; Mcfarland, Elizabeth J.; Muresan, Petronella; Capparelli, Edmund, V; Perlowski, Charlotte; Johnston, Benjamin; Bone, Frederic; Purdue, Lynette; Yin, Dwight E.; Moye, Jack; Spiegel, Hans M. L.; Majji, Sai; Theron, Gerhard B.; Mujuru, Hilda A.; Purswani, Murli; Alvarez, Grace; Deville, Jaime G.; Chambers, Carrie; Brown, Emily; Harding, Paul A.; Tobin, Nicole H.; Low, Kwang; Gama, Lucio
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Lamivudine dosing for preterm infants exposed to HIV: a population pharmacokinetic modelling and simulation study
errJOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
IF3.6
err2024-08-02
err1
PREAI
errBekker, Adrie; Capparelli, Edmund, V; Mirochnick, Mark; Clarke, Diana F.; Cotton, Mark F.; Shapiro, Roger; Mccarthy, Katie; Moye, Jack; Violari, Avy; Chokephaibulkit, Kulkanya; Abrams, Elaine; Penazzato, Martina; Ruel, Theodore D.; Cressey, Tim R.
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Sustained aviremia despite anti-retroviral therapy non-adherence in male children after in utero HIV transmission
errNATURE MEDICINE
IF50
err2024-06-06
err3
errOAAI
errBengu, Nomonde; Cromhout, Gabriela; Adland, Emily; Govender, Katya; Herbert, Nicholas; Lim, Nicholas; Fillis, Rowena; Sprenger, Kenneth; Vieira, Vinicius; Kannie, Samantha; van Lobenstein, Jeroen; Chinniah, Kogielambal; Kapongo, Constant; Bhoola, Roopesh; Krishna, Malini; Mchunu, Noxolo; Pascucci, Giuseppe Rubens; Cotugno, Nicola; Palma, Paolo; Tagarro, Alfredo; Rojo, Pablo; Roider, Julia; Garcia-Guerrero, Maria C.; Ochsenbauer, Christina; Groll, Andreas; Reddy, Kavidha; Giaquinto, Carlo; Rossi, Paolo; Hong, Seohyun; Dong, Krista; Ansari, M. Azim; Puertas, Maria C.; Ndung'u, Thumbi; Capparelli, Edmund; Lichterfeld, Mathias; Martinez-Picado, Javier; Kappes, John C.; Archary, Moherndran; Goulder, Philip
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Pharmacokinetics and Safety of Remdesivir in Pregnant and Nonpregnant Women With COVID-19: Results From IMPAACT 2032
errJOURNAL OF INFECTIOUS DISEASES
IF4.5
err2024-06-05
err0
errOAAI
errBrooks, Kristina M.; Baltrusaitis, Kristin; Clarke, Diana F.; Nachman, Sharon; Jao, Jennifer; Purswani, Murli U.; Agwu, Allison; Beneri, Christy; Deville, Jaime G.; Powis, Kathleen M.; Stek, Alice M.; Eke, Ahizechukwu C.; Shapiro, David E.; Capparelli, Edmund; Greene, Elizabeth; George, Kathleen; Yin, Dwight E.; Jean-Philippe, Patrick; Chakhtoura, Nahida; Bone, Frederic; Bacon, Kira; Johnston, Benjamin; Reding, Christina; Kersey, Kathryn; Humeniuk, Rita; Best, Brookie M.; Mirochnick, Mark; Momper, Jeremiah D.
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KINESIOPHOBIA CORRELATES WITH DISEASE ACTIVITY, QUALITY OF LIFE AND DEPRESSION IN PSORIATIC ARTHRITIS
errANNALS OF THE RHEUMATIC DISEASES
IF20.6
err2024-06-01
err0
PREAI
errCapparelli, E.; Iacovantuono, M.; Bonini, C.; Fiannacca, L.; Greco, E.; Triggianese, P.; Conigliaro, P.; Bergamini, A.; Chimenti., M. S.
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EXPLORING GENDER DIFFERENCES IN PATIENTS WITH IDIOPATHIC INFLAMMATORY MYOSITIS: DATA FROM A MONOCENTRIC ITALIAN COHORT
errANNALS OF THE RHEUMATIC DISEASES
IF20.6
err2024-06-01
err0
PREAI
errCela, E.; Capparelli, E.; D'antonio, A.; Greco, E.; Modica, S.; Bergamini, A.; Kroegler, B.; Chimenti, M. S.; Triggianese, P.
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errSave
FOCUSING ON INTERSTITIAL LUNG DISEASE IN IDIOPATHIC INFLAMMATORY MYOSITIS: REAL LIFE DATA FROM A SINGLE CENTER COHORT
errANNALS OF THE RHEUMATIC DISEASES
IF20.6
err2024-06-01
err0
PREAI
errCapparelli, E.; Cela, E.; Cristiano, I.; Kroegler, B.; Greco, E.; Puxeddu, E.; Cavalli, F.; Rogliani, P.; Chiocchi, M.; Chimenti, M. S.; Triggianese, P.
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errSave
Phase 1 trial evaluating safety and pharmacokinetics of HIV-1 broadly neutralizing mAbs 10E8VLS and VRC07-523LS
errJCI INSIGHT
IF6.1
err2024-04-08
err2
errOAAI
errAwan, Seemal F.; Pegu, Amarendra; Strom, Larisa; Carter, Cristina A.; Hendel, Cynthia S.; Holman, LaSonji A.; Costner, Pamela J.; Trofymenko, Olga; Dyer, Renunda; Gordon, Ingelise J.; Rothwell, Ro Shauna S.; Hickman, Somia P.; Conan-Cibotti, Michelle; Doria-Rose, Nicole A.; Lin, Bob C.; O'Connell, Sarah; Narpala, Sandeep R.; Almasri, Cassandra G.; Liu, Cuiping; Ko, Sungyoul; Kwon, Young D.; Namboodiri, Aryan M.; Pandey, Janardan P.; Arnold, Frank J.; Carlton, Kevin; Gall, Jason G.; Kwong, Peter D.; Capparelli, Edmund, V; Bailer, Robert T.; Mcdermott, Adrian B.; Chen, Grace L.; Koup, Richard A.; Mascola, John R.; Coates, Emily E.; Ledgerwood, Julie E.; Gaudinski, Martin R.
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Safety and pharmacokinetics of oral and long-acting injectable cabotegravir or long-acting injectable rilpivirine in virologically suppressed adolescents with HIV (IMPAACT 2017/MOCHA): a phase 1/2, multicentre, open-label, non-comparative, dose-finding study
errLANCET HIV
IF13
err2024-04-01
err6
errOAAI
errGaur, Aditya H.; Capparelli, Edmund, V; Calabrese, Katherine; Baltrusaitis, Kristin; Marzinke, Mark A.; Mccoig, Cynthia; Solingen-Ristea, Rodica M. Van; Mathiba, Sisinyana Ruth; Adeyeye, Adeola; Moye, John H.; Heckman, Barbara; Lowenthal, Elizabeth; Ward, Shawn; Milligan, Ryan; Samson, Pearl; Best, Brookie M.; Harrington, Conn M.; Ford, Susan L.; Huang, Jenny; Crauwels, Herta; Vandermeulen, Kati; Agwu, Allison L.; Smith-Anderson, Christiana; Camacho-Gonzalez, Andres; Ounchanum, Pradthana; Kneebone, Jared L.; Townley, Ellen; Moore, Carolyn Bolton
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HIV-1 reservoir size after neonatal antiretroviral therapy and the potential to evaluate antiretroviral-therapy-free remission (IMPAACT P1115): a phase 1/2 proof-of-concept study
errLANCET HIV
IF13
err2024-01-01
err5
errOAAI
errPersaud, Deborah; Bryson, Yvonne; Nelson, Bryan S.; Tierney, Camlin; Cotton, Mark F.; Coletti, Anne; Jao, Jennifer; Spector, Stephen A.; Mirochnick, Mark; Capparelli, Edmund, V; Costello, Diane; Szewczyk, Joseph; Nicodimus, Nicol; Stranix-Chibanda, Lynda; Kekitiinwa, Adeodata R.; Korutaro, Violet; Reding, Christina; Carrington, Mary N.; Majji, Sai; Yin, Dwight E.; Jean-Philippe, Patrick; Chadwick, Ellen G.
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POPULATION PHARMACOKINETICS OF MEROPENEM IN PEDIATRIC PATIENTS WITH SEPSIS
errCRITICAL CARE MEDICINE
IF6
err2023-12-14
err0
errOAAI
errJones, Douglas; Le, Jennifer; Momper, Jeremiah; Huynh, Julie; Mai, Annie; Vo, Brandon; Harvey, Helen; Stout, Dayna; Bradley, Erin; Capparelli, Edmund; Bradley, John
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Pharmacokinetics and safety of first-line tuberculosis drugs rifampin, isoniazid, ethambutol, and pyrazinamide during pregnancy and postpartum: results from IMPAACT P1026s
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2023-11-15
err5
errOAAI
errVan Schalkwyk, Marije; Bekker, Adrie; Decloedt, Eric; Wang, Jiajia; Theron, Gerhard B.; Cotton, Mark F.; Eke, Ahizechukwu C.; Cressey, Tim R.; Shapiro, David E.; Bacon, Kira; Knowles, Kevin; George, Kathleen; Browning, Renee; Chakhtoura, Nahida; Rungruengthanakit, Kittipong; Wiesner, Lubbe; Capparelli, Edmund V.; Stek, Alice M.; Mirochnick, Mark; Best, Brookie M.
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Broadly neutralizing antibody treatment maintained HIV suppression in children with favorable reservoir characteristics in Botswana
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2023-07-05
err16
PREAI
errShapiro, Roger L.; Ajibola, Gbolahan; Maswabi, Kenneth; Hughes, Michael; Nelson, Bryan S.; Niesar, Aischa; Holme, Molly Pretorius; Powis, Kathleen M.; Sakoi, Maureen; Batlang, Oganne; Moyo, Sikhulile; Mohammed, Terence; Maphorisa, Comfort; Bennett, Kara; Hu, Zixin; Giguel, Francoise; Reeves, Jacqueline D.; Reeves, Michael A.; Gao, Ce; Yu, Xu; Ackerman, Margaret E.; Mcdermott, Adrian; Cooper, Marlene; Caskey, Marina; Gama, Lucio; Jean-Philippe, Patrick; Yin, Dwight E.; Capparelli, Edmund V.; Lockman, Shahin; Makhema, Joseph; Kuritzkes, Daniel R.; Lichterfeld, Mathias
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Research Directions

No research directions
Co-authors
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