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PD3D®models as jacks-of-all-trades for cancer research and therapy response prediction Wedeken, Lena; Forbrig, Samantha; Herrera-Glomm, Katja; Loskutov, Juergen; Pfohl, Ulrike; Piven, Irina; Poehle, Michael; Regenbrecht, Manuela J.; Seller, Barbara; Yapto, Cynthia; Finkler, Sabine; Ruhe, Larissa; Adelmann, Quirin Graf; Reinhard, Christoph; Flechner, Marie; Uhlig, Katja; Kaul, David; Roohani, Siyer; Niethard, Maya; Sauer, Rica; Regenbrecht, Christian R. Share Save
Photon and Proton irradiation in Patient-derived, Three-Dimensional Soft Tissue Sarcoma Models Roohani, Siyer; Loskutov, Juergen; Heufelder, Jens; Ehret, Felix; Wedeken, Lena; Regenbrecht, Manuela; Sauer, Rica; Zips, Daniel; Denker, Andrea; Joussen, Antonia M.; Regenbrecht, Christian R. A.; Kaul, David Share Save
A combined computational and functional approach identifies IGF2BP2 as a driver of chemoresistance in a wide array of pre-clinical models of colorectal cancer Kendzia, Sandra; Franke, Susanne; Kroehler, Tarek; Golob-Schwarzl, Nicole; Schweiger, Caroline; Toeglhofer, Anna M.; Skofler, Christina; Uranitsch, Stefan; El-Heliebi, Amin; Fuchs, Julia; Punschart, Andreas; Stiegler, Philipp; Keil, Marlen; Hoffmann, Jens; Henderson, David; Lehrach, Hans; Yaspo, Marie-Laure; Reinhard, Christoph; Schaefer, Reinhold; Keilholz, Ulrich; Regenbrecht, Christian; Schicho, Rudolf; Fickert, Peter; Lax, Sigurd F.; Erdmann, Frank; Schulz, Marcel H.; Kiemer, Alexandra K.; Haybaeck, Johannes; Kessler, Sonja M. Share Save
Let's get physiological! Impact of media conditions on drug response to targeted therapies in CRC organoids Loskutov, Jurgen; Erdmann, Gerrit; Arndt, Anja; Adelmann, Quirin Graf; Dudys, Przemyslaw; Flechner, Marie; Nadolny, Madeleine; Osman, Katja; Pfohl, Ulrike; Reinhard, Christoph; Templin, Markus; Uhlig, Katja; Wedeken, Lena; Regenbrecht, Christian Share Save
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Peritoneal metastasis of colorectal cancer (pmCRC): identification of predictive molecular signatures by a novel preclinical platform of matching pmCRC PDX/PD3D models Dahlmann, Mathias; Gambara, Guido; Brzezicha, Bernadette; Popp, Oliver; Pachmayr, Eva; Wedeken, Lena; Pflaume, Alina; Mokritzkij, Margarita; Guel-Klein, Safak; Brandl, Andreas; Schweiger-Eisbacher, Caroline; Mertins, Philipp; Hoffmann, Jens; Keilholz, Ulrich; Walther, Wolfgang; Regenbrecht, Christian; Rau, Beate; Stein, Ulrike Share Save
High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53 Heuberger, Julian; Grinat, Johanna; Kosel, Frauke; Liu, Lichao; Kunz, Severine; Vidal, Ramon Oliveira; Keil, Marlen; Haybaeck, Johannes; Robine, Sylvie; Louvard, Daniel; Regenbrecht, Christian; Sporbert, Anje; Sauer, Sascha; von Eyss, Bjorn; Sigal, Michael; Birchmeier, Walter Share Save
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Reflection of neuroblastoma intratumor heterogeneity in the new OHC-NB1 disease model Thole, Theresa M.; Toedling, Joern; Spruessel, Annika; Pfeil, Sebastian; Savelyeva, Larissa; Capper, David; Messerschmidt, Clemens; Beule, Dieter; Groeneveld-Krentz, Stefanie; Eckert, Cornelia; Gambara, Guido; Henssen, Anton G.; Finkler, Sabine; Schulte, Johannes H.; Sieber, Anja; Bluethgen, Nils; Regenbrecht, Christian R. A.; Kuenkele, Annette; Lodrini, Marco; Eggert, Angelika; Deubzer, Hedwig E. Share Save
Modulating chemoresistance: Uncovering the role of mutant SMAD4R361Hin colorectal cancer using PDO and PDX models Pfohl, Ulrike; Silvestri, Alessandra; Schumacher, Dirk; Boehnke, Karsten; Haybaeck, Johannes; Bashir, Sanam; Kuehn, Ralf; Keil, Marlen; Schaefer, Reinhold; Walther, Wolfgang; Regenbrecht, Christian Share Save
Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures Schumacher, Dirk; Andrieux, Geoffroy; Boehnke, Karsten; Keil, Marlen; Silvestri, Alessandra; Silvestrov, Maxine; Keilholz, Ulrich; Haybaeck, Johannes; Erdmann, Gerrit; Sachse, Christoph; Templin, Markus; Hoffmann, Jens; Boerries, Melanie; Schaefer, Reinhold; Regenbrecht, Christian R. A. Share Save
Influence of eukaryotic translation initiation factor 6 on non-small cell lung cancer development and progression Gantenbein, Nadine; Bernhart, Eva; Anders, Ines; Golob-Schwarzl, Nicole; Krassnig, Stefanie; Wodlej, Christina; Brcic, Luka; Lindenmann, Joerg; Fink-Neuboeck, Nicole; Gollowitsch, Franz; Stacher-Priehse, Elvira; Asslaber, Martin; Gogg-Kamerer, Margit; Rolff, Jana; Hoffmann, Jens; Silvestri, Alessandra; Regenbrecht, Christian; Reinhard, Christoph; Pehserl, Anna-Maria; Pichler, Martin; Sokolova, Olga; Naumann, Michael; Mitterer, Valentin; Pertschy, Brigitte; Bergler, Helmut; Popper, Helmut; Sattler, Wolfgang; Haybaeck, Johannes Share Save
Novel patient-derived 3D (PD3D) cell models and matched patient-derived xenografts (PDX) from peritoneal metastasis of colorectal cancer for drug testing and biomarker analysis Regenbrecht, Christian R. A.; Gambara, Guido; Pachmayr, Eva; Silvestri, Alessandra; Dahlmann, Mathias; Brzezicha, Bernadette; Buettner, Britta; Rau, Beate; Keilholz, Ulrich; Stein, Urike; Walther, Wolfgang Share Save
Rapid generation of phenomic and functional profiles of patient-derived 3D cell culture models for identification of treatment vulnerabilities of breast cancer: Early results of the EFRE-PoP project Kiver, Verena I.; Gambara, Guido; Gorea, Olga; Blohmer, Jens-Uwe; Jurmeister, Philipp; Denkert, Carsten; Silvestri, Alessandra; Schweiger, Caroline M.; Silvestrov, Maxine; Keilholz, Ulrich; Regenbrecht, Christian R. Share Save
Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon Cancer Stem Cells Regan, Joseph L.; Schumacher, Dirk; Staudte, Stephanie; Steffen, Andreas; Haybaeck, Johannes; Keilholz, Ulrich; Schweiger, Caroline; Golob-Schwarzl, Nicole; Mumberg, Dominik; Henderson, David; Lehrach, Hans; Regenbrecht, Christian R. A.; Schaefer, Reinhold; Lange, Martin Share Save
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