Not logged in Organ-specific diversity of tumor immune microenvironment in metastatic pancreatic cancer Min, Jimin; Branchi, Vittorio; Rajapakshe, Kimal I.; Narayanan, Nisha; Pei, Guangsheng; Wang, Linghua; Grem, Jean L.; Caffrey, Thomas C.; Grandgenett, Paul M.; Hollingsworth, Michael A.; Guerrero, Paola A.; Maitra, Anirban Share Save
Disruption of sulfatide metabolism by targeting UGT8 is an actionable metabolic vulnerability for pancreatic cancer early interception Ballaro, Riccardo; Chen, Yihui; Thege, Fredrik I.; Dou, Rongzhang; Min, Jimin; Yip-Schneider, Michele; Zhang, Jianjun; Wu, Ranran; Irajizad, Ehsan; Makino, Yuki; Rajapakshe, Kimal I.; Hurd, Mark W.; Leon-Letelier, Ricardo A.; Ostrin, Edwin; Vykoukal, Jody; Dennison, Jennifer B.; Do, Kim-Anh; Hanash, Samir; Wolff, Robert A.; Guerrero, Paola A.; Kim, Michael P.; Schmidt, C. Max; Maitra, Anirban; Fahrmann, Johannes F. Share Save
A comprehensive spatial atlas of neoadjuvant chemoradiation therapy in resected pancreatic cancer identifies cellular & microenvironmental determinants of persister populations Bernard, Vincent; Jacobson, Galia; Rajapakshe, Kimal; Min, Jimin; Pei, Guangsheng; Lin, Daniel; Suresh, Ayush; Jiang, Dadi; Tzeng, Ching-Wei; Bhutani, Manoop S.; Wang, Linghua; Guerrero, Paola A.; Ludmir, Ethan B.; Koong, Albert C.; Maitra, Anirban; Taniguchi, Cullen M.; Koay, Eugene J. Share Save
Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer Dilly, Julien; Hoffman, Megan T.; Abbassi, Laleh; Li, Ziyue; Paradiso, Francesca; Parent, Brendan D.; Hennessey, Connor J.; Jordan, Alexander C.; Morgado, Micaela; Dasgupta, Shatavisha; Uribe, Giselle A.; Yang, Annan; Kapner, Kevin S.; Hambitzer, Felix P.; Qiang, Li; Feng, Hanrong; Geisberg, Jacob; Wang, Junning; Evans, Kyle E.; Lyu, Hengyu; Schalck, Aislyn; Feng, Ningping; Lopez, Anastasia M.; Bristow, Christopher A.; Kim, Michael P.; Rajapakshe, Kimal I.; Bahrambeigi, Vahid; Roth, Jennifer A.; Garg, Kavita; Guerrero, Paola A.; Stanger, Ben Z.; Cristea, Simona; Lowe, Scott W.; Baslan, Timour; Van Allen, Eliezer M.; Mancias, Joseph D.; Chan, Emily; Anderson, Abraham; Katlinskaya, Yuliya V.; Shalek, Alex K.; Hong, David S.; Pant, Shubham; Hallin, Jill; Anderes, Kenna; Olson, Peter; Heffernan, Timothy P.; Chugh, Seema; Christensen, James G.; Maitra, Anirban; Wolpin, Brian M.; Raghavan, Srivatsan; Nowak, Jonathan A.; Winter, Peter S.; Dougan, Stephanie K.; Aguirre, Andrew J. Share Save
Integrated spatial transcriptomics and lipidomics analyses of intraductal papillary mucinous neoplasm identifies enrichment of long chain sulfatide as an early metabolic alteration Chen, Yihui; Sans, Marta; Thege, Fredrik; Dou, Rongzhang; Min, Jimin; Yip-Schneider, Michele; Zhang, Jianjun; Wu, Ranran; Irajizad, Ehsan; Makino, Yuki; Rajapakshe, Kimal; Hurd, Mark; Leon-Letelier, Ricardo; Vykoukal, Jody; Dennison, Jennifer; Do, Kim-Anh; Wolff, Robert; Guerrero, Paola; Kim, Michael; Schmidt, Max; Maitra, Anirban; Hanash, Samir; Fahrmann, Johannes Share Save
Transcriptomic Profiling of Plasma Extracellular Vesicles Enables Reliable Annotation of the Cancer-Specific Transcriptome and Molecular Subtype Bahrambeigi, Vahid; Lee, Jaewon J.; Branchi, Vittorio; Rajapakshe, Kimal I.; Xu, Zhichao; Kui, Naishu; Henry, Jason T.; Kun, Wang; Stephens, Bret M.; Dhebat, Sarah; Hurd, Mark W.; Sun, Ryan; Yang, Peng; Ruppin, Eytan; Wang, Wenyi; Kopetz, Scott; Maitra, Anirban; Guerrero, Paola A. Share Save
CDK8 and CXCL2 remodel the tumor microenvironment to contribute to KRASG12D small molecule inhibition resistance in pancreatic ductal adenocarcinoma McAndrews, Kathleen M.; Mahadevan, Krishnan K.; Li, Bingrui; Sockwell, Amari M.; Morse, Sami J.; Kelly, Patience J.; Kirtley, Michelle L.; Conner, Meagan R.; Patel, Sarah I.; Khumbar, Shreyasee V.; Arian, Kent A.; Barekatain, Yasaman; Diaz, Barbara A. Moreno; Lyu, Hengyu; Sugimoto, Hikaru; Sthanam, Lakshmi Kavitha; Sobhani, Navid; Paradiso, Francesca; Bernard, Vincent; Guerrero, Paola; Ying, Haoqiang; Maitra, Anirban; Heffernan, Timothy P.; Kalluri, Raghu Share Save
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Spatial Transcriptomics of Intraductal Papillary Mucinous Neoplasms of the Pancreas Identifies NKX6-2 as a Driver of Gastric Differentiation and Indolent Biological Potential Sans, Marta; Makino, Yuki; Min, Jimin; Rajapakshe, Kimal I.; Yip-Schneider, Michele; Schmidt, C. Max; Hurd, Mark W.; Burks, Jared K.; Gomez, Javier A.; Thege, Fredrik I.; Fahrmann, Johannes F.; Wolff, Robert A.; Kim, Michael P.; Guerrero, Paola A.; Maitra, Anirban Share Save
Occult polyclonality of preclinical pancreatic cancer models drives in vitro evolution Monberg, Maria E.; Geiger, Heather; Lee, Jaewon J.; Sharma, Roshan; Semaan, Alexander; Bernard, Vincent; Wong, Justin; Wang, Fang; Liang, Shaoheng; Swartzlander, Daniel B.; Stephens, Bret M.; Katz, Matthew H. G.; Chen, Ken; Robine, Nicolas; Guerrero, Paola A.; Maitra, Anirban Share Save
Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression Cao, Shaolong; Wang, Jennifer R.; Ji, Shuangxi; Yang, Peng; Dai, Yaoyi; Guo, Shuai; Montierth, Matthew D.; Shen, John Paul; Zhao, Xiao; Chen, Jingxiao; Lee, Jaewon James; Guerrero, Paola A.; Spetsieris, Nicholas; Engedal, Nikolai; Taavitsainen, Sinja; Yu, Kaixian; Livingstone, Julie; Bhandari, Vinayak; Hubert, Shawna M.; Daw, Najat C.; Futreal, P. Andrew; Efstathiou, Eleni; Lim, Bora; Viale, Andrea; Zhang, Jianjun; Nykter, Matti; Czerniak, Bogdan A.; Brown, Powel H.; Swanton, Charles; Msaouel, Pavlos; Maitra, Anirban; Kopetz, Scott; Campbell, Peter; Speed, Terence P.; Boutros, Paul C.; Zhu, Hongtu; Urbanucci, Alfonso; Demeulemeester, Jonas; Van Loo, Peter; Wang, Wenyi Share Save
Loss of Rnf43 Accelerates Kras-Mediated Neoplasia and Remodels the Tumor Immune Microenvironment in Pancreatic Adenocarcinoma Hosein, Abdel Nasser; Dangol, Gita; Okumura, Takashi; Roszik, Jason; Rajapakshe, Kimal; Siemann, Megan; Zaid, Mohamed; Ghosh, Bidyut; Monberg, Maria; Guerrero, Paola A.; Singhi, Aatur; Haymaker, Cara L.; Clevers, Hans; Abou-Elkacem, Lotfi; Woermann, Sonja M.; Maitra, Anirban Share Save
Diagnostic value of digital droplet polymerase chain reaction and digital multiplexed detection of single-nucleotide variants in pancreatic cytology specimens collected by EUS-guided FNA Cazacu, Irina M.; Semaan, Alexander; Stephens, Bret; Swartzlander, Daniel B.; Guerrero, Paola A.; Singh, Ben S.; Lungulescu, Cristian Virgil; Danciulescu, Mihaela Maria; Harbiyeli, Irina F. Cherciu; Streata, Ioana; Popescu, Carmen; Saftoiu, Adrian; Roy-Chowdhuri, Sinchita; Maitra, Anirban; Bhutani, Manoop S. Share Save
Characterisation of circulating tumour cell phenotypes identifies a partial-EMT sub-population for clinical stratification of pancreatic cancer Semaan, Alexander; Bernard, Vincent; Kim, Dong U.; Lee, Jaewon J.; Huang, Jonathan; Kamyabi, Nabiollah; Stephens, Bret M.; Qiao, Wei; Varadhachary, Gauri R.; Katz, Matthew H.; Shen, Yu; San Lucas, Francis Anthony; Gascoyne, Peter; Alvarez, Hector A.; Maitra, Anirban; Guerrero, Paola A. Share Save
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Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts Bhagat, Tushar D.; Von Ahrens, Dagny; Dawlaty, Meelad; Zou, Yiyu; Baddour, Joelle; Achreja, Abhinav; Zhao, Hongyun; Yang, Lifeng; Patel, Brijesh; Kwak, Changsoo; Choudhary, Gaurav S.; Gordon-Mitchell, Shanisha; Aluri, Srinivas; Bhattacharyya, Sanchari; Sahu, Srabani; Bhagat, Prafulla; Yu, Yiting; Bartenstein, Matthias; Giricz, Orsi; Suzuki, Masako; Sohal, Davendra; Gupta, Sonal; Guerrero, Paola A.; Batra, Surinder; Goggins, Michael; Steidl, Ulrich; Greally, John; Agarwal, Beamon; Pradhan, Kith; Banerjee, Debabrata; Nagrath, Deepak; Maitra, Anirban; Verma, Amit Share Save
Single cell transcriptomic profiling of ex vivo tumoroid models reveal therapeutic vulnerabilities of pancreatic ductal adenocarcinoma Bernard, Vincent; San Lucas, F. Anthony; Huang, Jonathan; Powell, Reid T.; Guerrero, Paola A.; Semaan, Alexander; Stephan, Clifford C.; Davies, Peter; Varadhachary, Gauri R.; Katz, Matthew H.; Taniguchi, Cullen M.; Alvarez, Hector A.; Muthuswamy, Senthil; Maitra, Anirban Share Save
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