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SaveShare Save Share Save Clonal phylogenies inferred from bulk, single cell, and spatial transcriptomic analysis of epithelial cancers
Erickson, Andrew; Figiel, Sandy; Rajakumar, Timothy; Rao, Srinivasa; Yin, Wencheng; Doultsinos, Dimitrios; Magnussen, Anette; Singh, Reema; Poulose, Ninu; Bryant, Richard J.; Cussenot, Olivier; Hamdy, Freddie C.; Woodcock, Dan; Mills, Ian G.; Lamb, Alastair D. Share Save Single cell and spatial transcriptomics highlight the interaction of club-like cells with immunosuppressive myeloid cells in prostate cancerKiviaho, Antti; Eerola, Sini K.; Kallio, Heini M. L.; Andersen, Maria K.; Hoikka, Miina; Tiihonen, Aliisa M.; Salonen, Iida; Spotbeen, Xander; Giesen, Alexander; Parker, Charles T. A.; Taavitsainen, Sinja; Hantula, Olli; Marttinen, Mikael; Hermelo, Ismail; Ismail, Mazlina; Midtbust, Elise; Wess, Maximilian; Devlies, Wout; Sharma, Abhibhav; Krossa, Sebastian; Hakkinen, Tomi; Afyounian, Ebrahim; Vandereyken, Katy; Kint, Sam; Kesseli, Juha; Tolonen, Teemu; Tammela, Teuvo L. J.; Viset, Trond; Storkersen, Oystein; Giskeodegard, Guro F.; Rye, Morten B.; Murtola, Teemu; Erickson, Andrew; Latonen, Leena; Bova, G. Steven; Mills, Ian G.; Joniau, Steven; Swinnen, Johannes V.; Voet, Thierry; Mirtti, Tuomas; Attard, Gerhardt; Claessens, Frank; Visakorpi, Tapio; Rautajoki, Kirsi J.; Tessem, May-Britt; Urbanucci, Alfonso; Nykter, Matti Share Save SPATIAL TRANSCRIPTOMIC CLONAL DECONVOLUTION IDENTIFIES THE 'LETHAL CLONE' IN PROSTATE CANCER AS DEFINED BY ABILITY TO METASTASIZE TO LYMPH NODESYin, Wencheng; Figiel, Sandy; He, Mengxiao; Teague, Renuka; Anbarasan, Thineskrishna; Ranasinha, Nithesh; Singh, Reema; Poulose, Ninu; Doultsinos, Dimitrios; Abusamra, Sophia; Erickson, Andrew; Loda, Massimo; Verrill, Clare; Colling, Richard; Gill, Pelvender; Bryant, Richard; Cussenot, Olivier; Hamdy, Freddie; Woodcock, Dan; Mills, Ian; Lundeberg, Joakim; Lamb, Alastair Share Save EXPLORING STROMAL DYNAMICS IN PROSTATE CANCER: INSIGHTS FROM SPATIAL TRANSCRIPTOMIC ANALYSESFigiel, Sandy; Yin, Wencheng; He, Mengxiao; Teague, Renuka; Anbarasan, Thineskrishna; Ranasinha, Nithesh; Abusamra, Sophia; Singh, Reema; Doultsinos, Dimitrios; Poulose, Ninu; Erickson, Andrew; Verrill, Clare; Colling, Richard; Gill, Pelvender; Bryant, Richard J.; Cussenot, Olivier; Loda, Massimo; Hamdy, Freddie C.; Woodcock, Dan J.; Mills, Ian G.; Lundeberg, Joakim; Lamb, Alastair D. Share Save Share Save Share Save Spatial transcriptomic analysis of virtual prostate biopsy reveals confounding effect of tissue heterogeneity on genomic signaturesFigiel, Sandy; Yin, Wencheng; Doultsinos, Dimitrios; Erickson, Andrew; Poulose, Ninu; Singh, Reema; Magnussen, Anette; Anbarasan, Thineskrishna; Teague, Renuka; He, Mengxiao; Lundeberg, Joakim; Loda, Massimo; Verrill, Clare; Colling, Richard; Gill, Pelvender S.; Bryant, Richard J.; Hamdy, Freddie C.; Woodcock, Dan J.; Mills, Ian G.; Cussenot, Olivier; Lamb, Alastair D. Share Save The spatial landscape of clonal somatic copy number alterations in benign and malignant prostate epitheliaErickson, Andrew; He, Mengxiao; Berglund, Emelie; Marklund, Maja; Mirzazadeh, Reza; Schultz, Niklas; Kvastad, Linda; Andersson, Alma; Bergenstrahle, Ludvig; Bergenstrahle, Joseph; Larsson, Ludvig; Galicia, Leire Alonso; Shamikh, Alia; Basmaci, Elisa; De Stahl, Teresita Diaz; Rajakumar, Timothy; Doultsinos, Dimitrios; Thrane, Kim; Ji, Andrew L.; Khavari, Paul A.; Tarish, Firaz; Tanoglidi, Anna; Maaskola, Jonas; Colling, Richard; Mirtti, Tuomas; Hamdy, Freddie C.; Woodcock, Dan J.; Helleday, Thomas; Mills, Ian G.; Lamb, Alastair D.; Lundeberg, Joakim Share Save Prognostic impact of kallikrein-related peptidase transcript levels in prostate cancerLehto, Timo-Pekka K.; Kovanen, Ruusu-Maaria; Lintula, Susanna; Malen, Adrian; Sturenberg, Carolin; Erickson, Andrew; Pulkka, Olli-Pekka; Stenman, Ulf-Hakan; Diamandis, Eleftherios P.; Rannikko, Antti; Mirtti, Tuomas; Koistinen, Hannu Share Save PP2A methylesterase PME-1 suppresses anoikis and is associated with therapy relapse of PTEN-deficient prostate cancersAakula, Anna; Isomursu, Aleksi; Rupp, Christian; Erickson, Andrew; Gupta, Nikhil; Kauko, Otto; Shah, Pragya; Padzik, Artur; Pokharel, Yuba Raj; Kaur, Amanpreet; Li, Song-Ping; Trotman, Lloyd; Taimen, Pekka; Rannikko, Antti; Lammerding, Jan; Paatero, Ilkka; Mirtti, Tuomas; Ivaska, Johanna; Westermarck, Jukka Share Save Open-source singlecell spatial image analysis pipeline for ten-plex immunofluorescence of histological prostate cancer tissue sectionsSaila, Jenni; Schoonenberg, Annabrita; Valimaki, Katja; Lehto, Timo-Pekka; Sturenberg, Carolin; Erickson, Andrew; Rannikko, Antti; Kallioniemi, Olli; Paavolainen, Lassi; Mirtti, Tuomas; Pellinen, Teijo Share Save Spatio-temporal analysis of prostate tumors in situ suggests pre-existence of treatment-resistant clonesMarklund, Maja; Schultz, Niklas; Friedrich, Stefanie; Berglund, Emelie; Tarish, Firas; Tanoglidi, Anna; Liu, Yao; Bergenstrahle, Ludvig; Erickson, Andrew; Helleday, Thomas; Lamb, Alastair D.; Sonnhammer, Erik; Lundeberg, Joakim Share Save Share Save The spatial landscape of clonal somatic mutations in benign and malignant tissueErickson, Andrew; Berglund, Emelie; He, Mengxiao; Marklund, Maja; Mirzazadeh, Reza; Schultz, Niklas; Bergenstrahle, Ludvig; Kvastad, Linda; Andersson, Alma; Bergenstrahle, Joseph; Larsson, Ludvig; Shamikh, Alia; Basmaci, Elisa; De Stahl, Teresita Diaz; Rajakumar, Timothy; Thrane, Kim; Ji, Andrew L.; Khavari, Paul A.; Tarish, Firaz; Tanoglidi, Anna; Maaskola, Jonas; Colling, Richard; Mirtti, Tuomas; Hamdy, Freddie C.; Woodcock, Dan J.; Helleday, Thomas; Mills, Ian G.; Lamb, Alastair D. Share Save The Movember Global Action Plan 1 (GAP1): Unique Prostate Cancer Tissue Microarray ResourceOuellet, Veronique; Erickson, Andrew; Wiley, Kathy; Morrissey, Colm; Berge, Viktor; Moreno, Carlos S.; Tasken, Kristin Austlid; Trudel, Dominique; True, Lawrence D.; Lewis, Michael S.; Svindland, Aud; Ertunc, Onur; Vidal, Igor Damasceno; Osunkoya, Adeboye O.; Jones, Tracy; Bova, G. Steven; Lamminen, Tarja; Achtman, Ariel H.; Buzza, Mark; Kouspou, Michelle M.; Bigler, Steven A.; Zhou, Xinchun; Freedland, Stephen J.; Mes-Masson, Anne-Marie; Garraway, Isla P.; Trock, Bruce J.; Taimen, Pekka; Saad, Fred; Mirtti, Tuomas; Knudsen, Beatrice S.; De Marzo, Angelo M. Share Save Share Save Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapseTaavitsainen, S.; Engedal, N.; Cao, S.; Handle, F.; Erickson, A.; Prekovic, S.; Wetterskog, D.; Tolonen, T.; Vuorinen, E. M.; Kiviaho, A.; Natkin, R.; Hakkinen, T.; Devlies, W.; Henttinen, S.; Kaarijarvi, R.; Lahnalampi, M.; Kaljunen, H.; Nowakowska, K.; Syvala, H.; Blauer, M.; Cremaschi, P.; Claessens, F.; Visakorpi, T.; Tammela, T. L. J.; Murtola, T.; Granberg, K. J.; Lamb, A. D.; Ketola, K.; Mills, I. G.; Attard, G.; Wang, W.; Nykter, M.; Urbanucci, A. Share Save 
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