Not logged inTranslational genomics of osteoarthritis in 1,962,069 individuals
Hatzikotoulas, Konstantinos; Southam, Lorraine; Stefansdottir, Lilja; Boer, Cindy G.; Mcdonald, Merry-Lynn; Pett, J. Patrick; Park, Young-Chan; Tuerlings, Margo; Mulders, Rick; Barysenka, Andrei; Arruda, Ana Luiza; Tragante, Vinicius; Rocco, Alison; Bittner, Norbert; Chen, Shibo; Horn, Susanne; Srinivasasainagendra, Vinodh; To, Ken; Katsoula, Georgia; Kreitmaier, Peter; Tenghe, Amabel M. M.; Gilly, Arthur; Arbeeva, Liubov; Chen, Lane G.; de Pins, Agathe M.; Dochtermann, Daniel; Henkel, Cecilie; Hoeijer, Jonas; Ito, Shuji; Lind, Penelope A.; Lukusa-Sawalena, Bitota; Minn, Aye Ko Ko; Mola-Caminal, Marina; Narita, Akira; Reimann, Ene; Silberstein, Micah D.; Skogholt, Anne-Heidi; Tiwari, Hemant K.; Yau, Michelle S.; Yue, Ming; Zhao, Wei; Zhou, Jin J.; Alexiadis, George; Brunak, Soren; Campbell, Archie; Cheung, Jackson T. S.; Dowsett, Joseph; Faquih, Tariq; Faul, Jessica D.; Fei, Lijiang; Fenstad, Anne Marie; Funayama, Takamitsu; Gabrielsen, Maiken E.; Gocho, Chinatsu; Gromov, Kirill; Hansen, Thomas; Hudjashov, Georgi; Ingvarsson, Thorvaldur; Johnson, Jessica S.; Jonsson, Helgi; Kakehi, Saori; Karjalainen, Juha; Kasbohm, Elisa; Lemmelae, Susanna; Lin, Kuang; Liu, Xiaoxi; Loef, Marieke; Mangino, Massimo; Mccartney, Daniel; Millwood, Iona Y.; Richman, Joshua; Roberts, Mary B.; Ryan, Kathleen A.; Shivakumar, Manu; Skou, Soren T.; Sugimoto, Sachiyo; Suzuki, Ken; Takuwa, Hiroshi; Teder-Laving, Maris; Thomas, Laurent; Tomizuka, Kohei; Turman, Constance; Weiss, Stefan; Wu, Tian T.; Zengini, Eleni; Zhang, Yanfei; Babis, George; van Heel, David A.; Winsvold, Bendik; Gabrielsen, Maiken; Ferreira, Manuel Allen Revez; Baras, Aris; Barker, Tyler; Carey, David J.; Cheah, Kathryn S. E.; Chen, Zhengming; Cheung, Jason Pui-Yin; Daly, Mark; de Mutsert, Renee; Eaton, Charles B.; Erikstrup, Christian; Furnes, Ove Nord; Golightly, Yvonne M.; Gudbjartsson, Daniel F.; Hailer, Nils P.; Hayward, Caroline; Hochberg, Marc C.; Homuth, Georg; Huckins, Laura M.; Hveem, Kristian; Ikegawa, Shiro; Ishijima, Muneaki; Isomura, Minoru; Jones, Marcus; Kang, Jae H.; Kardia, Sharon L. R.; Kloppenburg, Margreet; Kraft, Peter; Kumahashi, Nobuyuki; Kuwata, Suguru; Lee, Ming Ta Michael; Lee, Phil H.; Lerner, Robin; Li, Liming; Lietman, Steve A.; Lotta, Luca; Lupton, Michelle K.; Maegi, Reedik; Martin, Nicholas G.; Mcalindon, Timothy E.; Medland, Sarah E.; Michaelsson, Karl; Mitchell, Braxton D.; Mook-Kanamori, Dennis O.; Morris, Andrew P.; Nabika, Toru; Nagami, Fuji; Nelson, Amanda E.; Pedersen, Ole Birger; Rosendaal, Frits R.; Sakurai-Yageta, Mika; Schmidt, Carsten Oliver; Sham, Pak Chung; Singh, Jasvinder A.; Smelser, Diane T.; Smith, Jennifer A.; Song, You-qiang; Sorensen, Erik; Tamiya, Gen; Tamura, Yoshifumi; Terao, Chikashi; Thorleifsson, Gudmar; Tsezou, Aspasia; Uchio, Yuji; Uitterlinden, A. G.; Ullum, Henrik; Valdes, Ana M.; Walters, Robin G.; Weir, David R.; Wilkinson, J. Mark; Winsvold, Bendik S.; Yamamoto, Masayuki; Zwart, John-Anker; Stefansson, Kari; Meulenbelt, Ingrid; Teichmann, Sarah A.; van Meurs, Joyce B. J.; Styrkarsdottir, Unnur; Zeggini, Eleftheria .png)
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SavePopulation-specific putative causal variants shape quantitative traitsKoyama, Satoshi; Liu, Xiaoxi; Koike, Yoshinao; Hikino, Keiko; Koido, Masaru; Li, Wei; Akaki, Kotaro; Tomizuka, Kohei; Ito, Shuji; Otomo, Nao; Suetsugu, Hiroyuki; Yoshino, Soichiro; Akiyama, Masato; Saito, Kohei; Ishikawa, Yuki; Benner, Christian; Natarajan, Pradeep; Ellinor, Patrick T.; Mushiroda, Taisei; Horikoshi, Momoko; Ikeda, Masashi; Iwata, Nakao; Matsuda, Koichi; Niida, Shumpei; Ozaki, Kouichi; Momozawa, Yukihide; Ikegawa, Shiro; Takeuchi, Osamu; Ito, Kaoru; Terao, Chikashi Share Save RNF213 Variants, Vasospastic Angina, and Risk of Fatal Myocardial InfarctionHikino, Keiko; Koyama, Satoshi; Ito, Kaoru; Koike, Yoshinao; Koido, Masaru; Matsumura, Takayoshi; Kurosawa, Ryo; Tomizuka, Kohei; Ito, Shuji; Liu, Xiaoxi; Ishikawa, Yuki; Momozawa, Yukihide; Morisaki, Takayuki; Kamatani, Yoichiro; Mushiroda, Taisei; Terao, Chikashi Share Save A genome-wide association study identifies a locus associated with knee extension strength in older Japanese individualsIto, Shuji; Takuwa, Hiroshi; Kakehi, Saori; Someya, Yuki; Kaga, Hideyoshi; Kumahashi, Nobuyuki; Kuwata, Suguru; Wakatsuki, Takuya; Kadowaki, Masaru; Yamamoto, Soichiro; Abe, Takafumi; Takeda, Miwako; Ishikawa, Yuki; Liu, Xiaoxi; Otomo, Nao; Suetsugu, Hiroyuki; Koike, Yoshinao; Hikino, Keiko; Tomizuka, Kohei; Momozawa, Yukihide; Ozaki, Kouichi; Isomura, Minoru; Nabika, Toru; Kaneko, Haruka; Ishijima, Muneaki; Kawamori, Ryuzo; Watada, Hirotaka; Tamura, Yoshifumi; Uchio, Yuji; Ikegawa, Shiro; Terao, Chikashi Share Save Decoding triancestral origins, archaic introgression, and natural selection in the Japanese population by whole-genome sequencingLiu, Xiaoxi; Koyama, Satoshi; Tomizuka, Kohei; Takata, Sadaaki; Ishikawa, Yuki; Ito, Shuji; Kosugi, Shunichi; Suzuki, Kunihiko; Hikino, Keiko; Koido, Masaru; Koike, Yoshinao; Horikoshi, Momoko; Gakuhari, Takashi; Ikegawa, Shiro; Matsuda, Kochi; Momozawa, Yukihide; Ito, Kaoru; Kamatani, Yoichiro; Terao, Chikashi Share Save GWAS for systemic sclerosis identifies six novel susceptibility loci including one in the Fcγ receptor regionIshikawa, Yuki; Tanaka, Nao; Asano, Yoshihide; Kodera, Masanari; Shirai, Yuichiro; Akahoshi, Mitsuteru; Hasegawa, Minoru; Matsushita, Takashi; Saito, Kazuyoshi; Motegi, Sei-ichiro; Yoshifuji, Hajime; Yoshizaki, Ayumi; Kohmoto, Tomohiro; Takagi, Kae; Oka, Akira; Kanda, Miho; Tanaka, Yoshihito; Ito, Yumi; Nakano, Kazuhisa; Kasamatsu, Hiroshi; Utsunomiya, Akira; Sekiguchi, Akiko; Niiro, Hiroaki; Jinnin, Masatoshi; Makino, Katsunari; Makino, Takamitsu; Ihn, Hironobu; Yamamoto, Motohisa; Suzuki, Chisako; Takahashi, Hiroki; Nishida, Emi; Morita, Akimichi; Yamamoto, Toshiyuki; Fujimoto, Manabu; Kondo, Yuya; Goto, Daisuke; Sumida, Takayuki; Ayuzawa, Naho; Yanagida, Hidetoshi; Horita, Tetsuya; Atsumi, Tatsuya; Endo, Hirahito; Shima, Yoshihito; Kumanogoh, Atsushi; Hirata, Jun; Otomo, Nao; Suetsugu, Hiroyuki; Koike, Yoshinao; Tomizuka, Kohei; Yoshino, Soichiro; Liu, Xiaoxi; Ito, Shuji; Hikino, Keiko; Suzuki, Akari; Momozawa, Yukihide; Ikegawa, Shiro; Tanaka, Yoshiya; Ishikawa, Osamu; Takehara, Kazuhiko; Torii, Takeshi; Sato, Shinichi; Okada, Yukinori; Mimori, Tsuneyo; Matsuda, Fumihiko; Matsuda, Koichi; Amariuta, Tiffany; Imoto, Issei; Matsuo, Keitaro; Kuwana, Masataka; Kawaguchi, Yasushi; Ohmura, Koichiro; Terao, Chikashi Share Save Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variantsWang, Anqi; Shen, Jiayi; Rodriguez, Alex A.; Saunders, Edward J.; Chen, Fei; Janivara, Rohini; Darst, Burcu F.; Sheng, Xin; Xu, Yili; Chou, Alisha J.; Benlloch, Sara; Dadaev, Tokhir; Brook, Mark N.; Plym, Anna; Sahimi, Ali; Hoffman, Thomas J.; Takahashi, Atushi; Matsuda, Koichi; Momozawa, Yukihide; Fujita, Masashi; Laisk, Triin; Figueredo, Jessica; Muir, Kenneth; Ito, Shuji; Liu, Xiaoxi; Uchio, Yuji; Kubo, Michiaki; Kamatani, Yoichiro; Lophatananon, Artitaya; Wan, Peggy; Andrews, Caroline; Lori, Adriana; Choudhury, Parichoy P.; Schleutker, Johanna; Tammela, Teuvo L. J.; Sipeky, Csilla; Auvinen, Anssi; Giles, Graham G.; Southey, Melissa C.; MacInnis, Robert J.; Cybulski, Cezary; Wokolorczyk, Dominika; Lubinski, Jan; Rentsch, Christopher T.; Cho, Kelly; Mcmahon, Benjamin H.; Neal, David E.; Donovan, Jenny L.; Hamdy, Freddie C.; Martin, Richard M.; Nordestgaard, Borge G.; Nielsen, Sune F.; Weischer, Maren; Bojesen, Stig E.; Roder, Andreas; Stroomberg, Hein V.; Batra, Jyotsna; Chambers, Suzanne; Horvath, Lisa; Clements, Judith A.; Tilly, Wayne; Risbridger, Gail P.; Gronberg, Henrik; Aly, Markus; Szulkin, Robert; Eklund, Martin; Nordstrom, Tobias; Pashayan, Nora; Dunning, Alison M.; Ghoussaini, Maya; Travis, Ruth C.; Key, Tim J.; Riboli, Elio; Park, Jong Y.; Sellers, Thomas A.; Lin, Hui-Yi; Albanes, Demetrius; Weinstein, Stephanie; Cook, Michael B.; Mucci, Lorelei A.; Giovannucci, Edward; Lindstrom, Sara; Kraft, Peter; Hunter, David J.; Penney, Kathryn L.; Turman, Constance; Tangen, Catherine M.; Goodman, Phyllis J.; Thompson, Ian M., Jr.; Hamilton, Robert J.; Fleshner, Neil E.; Finelli, Antonio; Parent, Marie-Elise; Stanford, Janet L.; Ostrander, Elaine A.; Koutros, Stella; Freeman, Laura E. Beane; Stampfer, Meir; Wolk, Alicja; Hakansson, Niclas; Andriole, Gerald L.; Hoover, Robert N.; Machiela, Mitchell J.; Sorensen, Karina Dalsgaard; Borre, Michael; Blot, William J.; Zheng, Wei; Yeboah, Edward D.; Mensah, James E.; Lu, Yong-Jie; Zhang, Hong-Wei; Feng, Ninghan; Mao, Xueying; Wu, Yudong; Zhao, Shan-Chao; Sun, Zan; Thibodeau, Stephen N.; McDonnell, Shannon K.; Schaid, Daniel J.; West, Catharine M. L.; Barnett, Gill; Maier, Christiane; Schnoeller, Thomas; Luedeke, Manuel; Kibel, Adam S.; Drake, Bettina F.; Cussenot, Olivier; Cancel-Tassin, Geraldine; Menegaux, Florence; Truong, Therese; Koudou, Yves Akoli; John, Esther M.; Grindedal, Eli Marie; Maehle, Lovise; Khaw, Kay-Tee; Ingles, Sue A.; Stern, Mariana C.; Vega, Ana; Gomez-Caamano, Antonio; Fachal, Laura; Rosenstein, Barry S.; Kerns, Sarah L.; Ostrer, Harry; Teixeira, Manuel R.; Paulo, Paula; Brandao, Andreia; Watya, Stephen; Lubwama, Alexander; Bensen, Jeannette T.; Butler, Ebonee N.; Mohler, James L.; Taylor, Jack A.; Kogevinas, Manolis; Dierssen-Sotos, Trinidad; Castano-Vinyals, Gemma; Cannon-Albright, Lisa; Teerlink, Craig C.; Huff, Chad D.; Pilie, Patrick; Yu, Yao; Bohlender, Ryan J.; Gu, Jian; Strom, Sara S.; Multigner, Luc; Blanchet, Pascal; Brureau, Laurent; Kaneva, Radka; Slavov, Chavdar; Mitev, Vanio; Leach, Robin J.; Brenner, Hermann; Chen, Xuechen; Holleczek, Bernd; Schoettker, Ben; Klein, Eric A.; Hsing, Ann W.; Kittles, Rick A.; Murphy, Adam B.; Logothetis, Christopher J.; Kim, Jeri; Neuhausen, Susan L.; Steele, Linda; Ding, Yuan Chun; Isaacs, William B.; Nemesure, Barbara; Hennis, Anselm J. M.; Carpten, John; Pandha, Hardev; Michael, Agnieszka; De Ruyck, Kim; De Meerleer, Gert; Ost, Piet; Xu, Jianfeng; Razack, Azad; Lim, Jasmine; Teo, Soo-Hwang; Newcomb, Lisa F.; Lin, Daniel W.; Fowke, Jay H.; Neslund-Dudas, Christine M.; Rybicki, Benjamin A.; Gamulin, Marija; Lessel, Davor; Kulis, Tomislav; Usmani, Nawaid; Abraham, Aswin; Singhal, Sandeep; Parliament, Matthew; Claessens, Frank; Joniau, Steven; Van den Broeck, Thomas; Gago-Dominguez, Manuela; Castelao, Jose Esteban; Martinez, Maria Elena; Larkin, Samantha; Townsend, Paul A.; Aukim-Hastie, Claire; Bush, William S.; Aldrich, Melinda C.; Crawford, Dana C.; Srivastava, Shiv; Cullen, Jennifer; Petrovics, Gyorgy; Casey, Graham; Wang, Ying; Tettey, Yao; Lachance, Joseph; Tang, Wei; Biritwum, Richard B.; Adjei, Andrew A.; Tay, Evelyn; Truelove, Ann; Niwa, Shelley; Yamoah, Kosj; Govindasami, Koveela; Chokkalingam, Anand P.; Keaton, Jacob M.; Hellwege, Jacklyn N.; Clark, Peter E.; Jalloh, Mohamed; Gueye, Serigne M.; Niang, Lamine; Ogunbiyi, Olufemi; Shittu, Olayiwola; Amodu, Olukemi; Adebiyi, Akindele O.; Aisuodionoe-Shadrach, Oseremen I.; Ajibola, Hafees O.; Jamda, Mustapha A.; Oluwole, Olabode P.; Nwegbu, Maxwell; Adusei, Ben; Mante, Sunny; Darkwa-Abrahams, Afua; Diop, Halimatou; Gundell, Susan M.; Roobol, Monique J.; Jenster, Guido; van Schaik, Ron H. N.; Hu, Jennifer J.; Sanderson, Maureen; Kachuri, Linda; Varma, Rohit; McKean-Cowdin, Roberta; Torres, Mina; Preuss, Michael H.; Loos, Ruth J. F.; Zawistowski, Matthew; Zollner, Sebastian; Lu, Zeyun; Van Den Eeden, Stephen K.; Easton, Douglas F.; Ambs, Stefan; Edwards, Todd L.; Magi, Reedik; Rebbeck, Timothy R.; Fritsche, Lars; Chanock, Stephen J.; Berndt, Sonja I.; Wiklund, Fredrik; Nakagawa, Hidewaki; Witte, John S.; Gaziano, J. Michael; Justice, Amy C.; Mancuso, Nick; Terao, Chikashi; Eeles, Rosalind A.; Kote-Jarai, Zsofia; Madduri, Ravi K.; Conti, David V.; Haiman, Christopher A. Share Save Natural Selection Signatures in the Hondo and Ryukyu Japanese SubpopulationsLiu, Xiaoxi; Matsunami, Masatoshi; Horikoshi, Momoko; Ito, Shuji; Ishikawa, Yuki; Suzuki, Kunihiko; Momozawa, Yukihide; Niida, Shumpei; Kimura, Ryosuke; Ozaki, Kouichi; Maeda, Shiro; Imamura, Minako; Terao, Chikashi Share Save Comparing the MiniBox™ and the Chestac-8900® for pulmonary function testingMatsuki, T.; Yanagi, H.; Koba, T.; Aso, H.; Sakaguchi, S.; Ito, S.; Kouyama, K.; Furuta, K.; Miyazaki, A.; Sumitani, H.; Yokoyama, M.; Miyamoto, S.; Fukai, M.; Hashimoto, K.; Nii, T.; Hashimoto, H.; Fukushima, K.; Tsujino, K.; Miki, K.; Kida, H.; Kumanogoh, A. Share Save Androgen receptor binding sites enabling genetic prediction of mortality due to prostate cancer in cancer-free subjectsIto, Shuji; Liu, Xiaoxi; Ishikawa, Yuki; Conti, David D.; Otomo, Nao; Kote-Jarai, Zsofia; Suetsugu, Hiroyuki; Eeles, Rosalind A.; Koike, Yoshinao; Hikino, Keiko; Yoshino, Soichiro; Tomizuka, Kohei; Horikoshi, Momoko; Ito, Kaoru; Uchio, Yuji; Momozawa, Yukihide; Kubo, Michiaki; BioBank Japan Project, Shiro; Kamatani, Yoichiro; Matsuda, Koichi; Haiman, Christopher A.; Ikegawa, Shiro; Nakagawa, Hidewaki; Terao, Chikashi Share Save Genetic insights into ossification of the posterior longitudinal ligament of the spineKoike, Yoshinao; Takahata, Masahiko; Nakajima, Masahiro; Otomo, Nao; Suetsugu, Hiroyuki; Liu, Xiaoxi; Endo, Tsutomu; Imagama, Shiro; Kobayashi, Kazuyoshi; Kaito, Takashi; Kato, Satoshi; Kawaguchi, Yoshiharu; Kanayama, Masahiro; Sakai, Hiroaki; Tsuji, Takashi; Miyamoto, Takeshi; Inose, Hiroyuki; Yoshii, Toshitaka; Kashii, Masafumi; Nakashima, Hiroaki; Ando, Kei; Taniguchi, Yuki; Takeuchi, Kazuhiro; Ito, Shuji; Tomizuka, Kohei; Hikino, Keiko; Iwasaki, Yusuke; Kamatani, Yoichiro; Maeda, Shingo; Nakajima, Hideaki; Mori, Kanji; Seichi, Atsushi; Fujibayashi, Shunsuke; Kanchiku, Tsukasa; Watanabe, Kei; Tanaka, Toshihiro; Kida, Kazunobu; Kobayashi, Sho; Takahashi, Masahito; Yamada, Kei; Takuwa, Hiroshi; Lu, Hsing-Fang; Niida, Shumpei; Ozaki, Kouichi; Momozawa, Yukihide; Yamazaki, Masashi; Okawa, Atsushi; Matsumoto, Morio; Iwasaki, Norimasa; Terao, Chikashi; Ikegawa, Shiro Share Save Genetic Architectures Underlie Onset Age of Atopic DermatitisHikino, Keiko; Tanaka, Nao; Koido, Masaru; Tomizuka, Kohei; Koike, Yoshinao; Ito, Shuji; Suzuki, Akari; Momozawa, Yukihide; Kamatani, Yoichiro; Mushiroda, Taisei; Terao, Chikashi Share Save Role of Lysine-Specific Demethylase 1 in Metabolically Integrating Osteoclast Differentiation and Inflammatory Bone Resorption Through Hypoxia-Inducible Factor 1α and E2F1Doi, Kohei; Murata, Koichi; Ito, Shuji; Suzuki, Akari; Terao, Chikashi; Ishie, Shinichiro; Umemoto, Akio; Murotani, Yoshiki; Nishitani, Kohei; Yoshitomi, Hiroyuki; Fujii, Takayuki; Watanabe, Ryu; Hashimoto, Motomu; Murakami, Kosaku; Tanaka, Masao; Ito, Hiromu; Park-Min, Kyung-Hyun; Ivashkiv, Lionel B.; Morinobu, Akio; Matsuda, Shuichi Share Save Share Save Share Save Share Save Share Save Share Save Share Save RECHALLENGE WITH EGFR-TKI AFTER A DRUG HOLIDAY, RETROSPECTIVE STUDY IN SINGLE INSTITUTIONKodani, M.; Igishi, T.; Sakamoto, T.; Touge, H.; Izumi, H.; Ito, S.; Kurai, J.; Yamaguchi, K.; Nakamoto, M.; Shimizu, E. 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