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Caspase-1 causes truncation and aggregation of the Parkinson's disease-associated protein α-synuclein Wang, Wei; Nguyen, Linh T. T.; Burlak, Christopher; Chegini, Fariba; Guo, Feng; Chataway, Tim; Ju, Shulin; Fisher, Oriana S.; Miller, David W.; Datta, Debajyoti; Wu, Fang; Wu, Chun-Xiang; Landeru, Anuradha; Wells, James A.; Cookson, Mark R.; Boxer, Matthew B.; Thomas, Craig J.; Gai, Wei Ping; Ringe, Dagmar; Petsko, Gregory A.; Hoang, Quyen Q. Share Save
Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1 Barmada, Sami J.; Ju, Shulin; Arjun, Arpana; Batarse, Anthony; Archbold, Hilary C.; Peisach, Daniel; Li, Xingli; Zhang, Yuxi; Tank, Elizabeth M. H.; Qiu, Haiyan; Huang, Eric J.; Ringe, Dagmar; Petsko, Gregory A.; Finkbeiner, Steven Share Save
Latrepirdine (Dimebon™) Enhances Autophagy and Reduces Intracellular GFP-Aβ42 Levels in Yeast Bharadwaj, Prashant R.; Verdile, Giuseppe; Barr, Renae K.; Gupta, Veer; Steele, John W.; Lachenmayer, M. Lenard; Yue, Zhenyu; Ehrlich, Michelle E.; Petsko, Gregory; Ju, Shulin; Ringe, Dagmar; Sankovich, Sonia E.; Caine, Joanne M.; Macreadie, Ian G.; Gandy, Sam; Martins, Ralph N. Share Save
Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain Steele, J. W.; Ju, S.; Lachenmayer, M. L.; Liken, J.; Stock, A.; Kim, S. H.; Delgado, L. M.; Alfaro, I. E.; Bernales, S.; Verdile, G.; Bharadwaj, P.; Gupta, V.; Barr, R.; Friss, A.; Dolios, G.; Wang, R.; Ringe, D.; Protter, A. A.; Martins, R. N.; Ehrlich, M. E.; Yue, Z.; Petsko, G. A.; Gandy, S. Share Save
A soluble α-synuclein construct forms a dynamic tetramer Wang, Wei; Perovic, Iva; Chittuluru, Johnathan; Kaganovich, Alice; Nguyen, Linh T. T.; Liao, Jingling; Auclair, Jared R.; Johnson, Derrick; Landeru, Anuradha; Simorellis, Alana K.; Ju, Shulin; Cookson, Mark R.; Asturias, Francisco J.; Agar, Jeffrey N.; Webb, Brian N.; Kang, ChulHee; Ringe, Dagmar; Petsko, Gregory A.; Pochapsky, Thomas C.; Hoang, Quyen Q. Share Save
Polyamine pathway contributes to the pathogenesis of Parkinson disease Lewandowski, Nicole M.; Ju, Shulin; Verbitsky, Miguel; Ross, Barbara; Geddie, Melissa L.; Rockenstein, Edward; Adame, Anthony; Muhammad, Alim; Vonsattel, Jean Paul; Ringe, Dagmar; Cote, Lucien; Lindquist, Susan; Masliah, Eliezer; Petsko, Gregory A.; Marder, Karen; Clark, Lorraine N.; Small, Scott A. Share Save
Detection of ligand binding hot spots on protein surfaces via fragment-based methods: application to DJ-1 and glucocerebrosidase Landon, Melissa R.; Lieberman, Raquel L.; Hoang, Quyen Q.; Ju, Shulin; Caaveiro, Jose M. M.; Orwig, Susan D.; Kozakov, Dima; Brenke, Ryan; Chuang, Gwo-Yu; Beglov, Dmitry; Vajda, Sandor; Petsko, Gregory A.; Ringe, Dagmar Share Save
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