arrow
Back
J

Ji‐Eun Seo

U.S. Food and Drug Administration

14H-index
33Paper Count
469Citation Count
Published Papers 17
Publication Date
Genotoxicity evaluation of ten nitrosamine drug substance-related impurities using 2D and 3D HepaRG cells
err2025-07-09
err0
PREAI
errJi-Eun Seo; Hannah Xu; Xilin Li; Aisar H. Atrakchi; Timothy McGovern; Karen L. Davis Bruno; David A. Keire; Nan Mei; Robert H. Heflich; Xiaoqing Guo
errShare
errSave
Integration of the rat liver micronucleus assay into a 28-day treatment protocol: testing the genotoxicity of 4 small-molecule nitrosamines with different carcinogenic potencies and tumor target specificities
err2025-01-03
err0
PREAI
errGuo, Xiaoqing; Seo, Ji-Eun; Xu, Hannah; Yan, Jian; Malhi, Pritpal; Atrakchi, Aisar H.; Mcgovern, Timothy; Bruno, Karen L. Davis; Heflich, Robert H.; Chen, Tao
errShare
errSave
Evaluating the mutagenicity of N-nitrosodimethylamine in 2D and 3D HepaRG cell cultures using error-corrected next generation sequencing
err2024-04-07
err4
errOAAI
errSeo, Ji-Eun; Le, Yuan; Revollo, Javier; Miranda-Colon, Jaime; Xu, Hannah; McKinzie, Page; Mei, Nan; Chen, Tao; Heflich, Robert H.; Zhou, Tong; Robison, Timothy; Bonzo, Jessica A.; Guo, Xiaoqing
errShare
errSave
The involvement of hepatic cytochrome P450s in the cytotoxicity of lapatinib
err2023-10-03
err7
errOAAI
errChen, Si; Li, Xilin; Li, Yuxi; He, Xiaobo; Bryant, Matthew; Qin, Xuan; Li, Feng; Seo, Ji-Eun; Guo, Xiaoqing; Mei, Nan; Guo, Lei
errShare
errSave
Genotoxicity assessment of eight nitrosamines using 2D and 3D HepaRG cell models
err2023-07-24
err5
PREAI
errSeo, Ji-Eun; Yu, Joshua Z.; Xu, Hannah; Li, Xilin; Atrakchi, Aisar H.; McGovern, Timothy J.; Bruno, Karen L. Davis; Mei, Nan; Heflich, Robert H.; Guo, Xiaoqing
errShare
errSave
Revisiting the mutagenicity and genotoxicity of N-nitroso propranolol in bacterial and human in vitro assays
err2023-06-01
err11
errOAAI
errLi, Xilin; Le, Yuan; Seo, Ji-Eun; Guo, Xiaoqing; Li, Yuxi; Chen, Si; Mittelstaedt, Roberta A.; Moore, Nyosha; Guerrero, Sharon; Sims, Audrey; King, Sruthi T.; Atrakchi, Aisar H.; Mcgovern, Timothy J.; Davis-Bruno, Karen L.; Keire, David A.; Elespuru, Rosalie K.; Heflich, Robert H.; Mei, Nan
errShare
errSave
High-throughput micronucleus assay using three-dimensional HepaRG spheroids for in vitro genotoxicity testing
err2023-02-27
err8
PREAI
errSeo, Ji-Eun; Li, Xilin; Le, Yuan; Mei, Nan; Zhou, Tong; Guo, Xiaoqing
errShare
errSave
Genotoxicity evaluation using primary hepatocytes isolated from rhesus macaque (Macaca mulatta)
err2021-10-01
err3
PREAI
errSeo, Ji-Eun; Davis, Kelly; Malhi, Pritpal; He, Xiaobo; Bryant, Matthew; Talpos, John; Burks, Susan; Mei, Nan; Guo, Xiaoqing
errShare
errSave
Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
err2021-04-15
err4
errOAAI
errSeo, Ji-Eun; Guo, Xiaoqing; Petibone, Dayton M.; Shelton, Sharon D.; Chen, Ying; Li, Xilin; Tryndyak, Volodymyr; Smith-Roe, Stephanie L.; Witt, Kristine L.; Mei, Nan; Manjanatha, Mugimane G.
errShare
errSave
Development and Application of TK6-derived Cells Expressing Human Cytochrome P450s for Genotoxicity Testing (vol 175, pg 251, 2020)
err2020-08-26
err0
errOAAI
errLi, Xilin; Chen, Si; Guo, Xiaoqing; Wu, Qiangen; Seo, Ji-Eun; Guo, Lei; Manjanatha, Mugimane G.; Zhou, Tong; Witt, Kristine L.; Mei, Nan
errShare
errSave
Performance of high-throughput CometChip assay using primary human hepatocytes: a comparison of DNA damage responses with in vitro human hepatoma cell lines
err2020-04-22
err17
PREAI
errSeo, Ji-Eun; Wu, Qiangen; Bryant, Matthew; Ren, Lijun; Shi, Qiang; Robison, Timothy W.; Mei, Nan; Manjanatha, Mugimane G.; Guo, Xiaoqing
errShare
errSave
Development and Application of TK6-derived Cells Expressing Human Cytochrome P450s for Genotoxicity Testing
err2020-03-11
err21
errOAAI
errLi, Xilin; Chen, Si; Guo, Xiaoqing; Wu, Qiangen; Seo, Ji-Eun; Guo, Lei; Manjanatha, Mugimane G.; Zhou, Tong; Witt, Kristine L.; Mei, Nan
errShare
errSave
Quantitative comparison of in vitro genotoxicity between metabolically competent HepaRG cells and HepG2 cells using the high-throughput high-content CometChip assay
err2019-02-21
err35
PREAI
errSeo, Ji-Eun; Tryndyak, Volodymyr; Wu, Qiangen; Dreval, Kostiantyn; Pogribny, Igor; Bryant, Matthew; Zhou, Tong; Robison, Timothy W.; Mei, Nan; Guo, Xiaoqing
errShare
errSave
Whole genome sequencing analysis of small and large colony mutants from the mouse lymphoma assay
err2018-10-17
err3
PREAI
errGuo, Xiaoqing; Pan, Bohu; Seo, Ji-Eun; Chen, Ying; Yan, Jian; Mei, Nan; Chen, Tao
errShare
errSave
Comparative Genotoxicity of TEMPO and 3 of Its Derivatives in Mouse Lymphoma Cells
err2018-01-27
err17
errOAAI
errGuo, Xiaoqing; Seo, Ji-Eun; Bryce, Steven M.; Tan, Jenna A.; Wu, Qiangen; Dial, Stacey L.; Moore, Martha M.; Mei, Nan
errShare
errSave