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SaveIntegration of the rat liver micronucleus assay into a 28-day treatment protocol: testing the genotoxicity of 4 small-molecule nitrosamines with different carcinogenic potencies and tumor target specificities
Guo, Xiaoqing; Seo, Ji-Eun; Xu, Hannah; Yan, Jian; Malhi, Pritpal; Atrakchi, Aisar H.; Mcgovern, Timothy; Bruno, Karen L. Davis; Heflich, Robert H.; Chen, Tao
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SaveEvaluating the mutagenicity of N-nitrosodimethylamine in 2D and 3D HepaRG cell cultures using error-corrected next generation sequencing
Seo, Ji-Eun; Le, Yuan; Revollo, Javier; Miranda-Colon, Jaime; Xu, Hannah; McKinzie, Page; Mei, Nan; Chen, Tao; Heflich, Robert H.; Zhou, Tong; Robison, Timothy; Bonzo, Jessica A.; Guo, Xiaoqing
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SaveThe involvement of hepatic cytochrome P450s in the cytotoxicity of lapatinib
Chen, Si; Li, Xilin; Li, Yuxi; He, Xiaobo; Bryant, Matthew; Qin, Xuan; Li, Feng; Seo, Ji-Eun; Guo, Xiaoqing; Mei, Nan; Guo, Lei
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SaveGenotoxicity assessment of eight nitrosamines using 2D and 3D HepaRG cell models
Seo, Ji-Eun; Yu, Joshua Z.; Xu, Hannah; Li, Xilin; Atrakchi, Aisar H.; McGovern, Timothy J.; Bruno, Karen L. Davis; Mei, Nan; Heflich, Robert H.; Guo, Xiaoqing
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SaveRevisiting the mutagenicity and genotoxicity of N-nitroso propranolol in bacterial and human in vitro assays
Li, Xilin; Le, Yuan; Seo, Ji-Eun; Guo, Xiaoqing; Li, Yuxi; Chen, Si; Mittelstaedt, Roberta A.; Moore, Nyosha; Guerrero, Sharon; Sims, Audrey; King, Sruthi T.; Atrakchi, Aisar H.; Mcgovern, Timothy J.; Davis-Bruno, Karen L.; Keire, David A.; Elespuru, Rosalie K.; Heflich, Robert H.; Mei, Nan
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SaveMechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells
Seo, Ji-Eun; Guo, Xiaoqing; Petibone, Dayton M.; Shelton, Sharon D.; Chen, Ying; Li, Xilin; Tryndyak, Volodymyr; Smith-Roe, Stephanie L.; Witt, Kristine L.; Mei, Nan; Manjanatha, Mugimane G.
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SaveDevelopment and Application of TK6-derived Cells Expressing Human Cytochrome P450s for Genotoxicity Testing (vol 175, pg 251, 2020)
Li, Xilin; Chen, Si; Guo, Xiaoqing; Wu, Qiangen; Seo, Ji-Eun; Guo, Lei; Manjanatha, Mugimane G.; Zhou, Tong; Witt, Kristine L.; Mei, Nan
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SaveDevelopment and Application of TK6-derived Cells Expressing Human Cytochrome P450s for Genotoxicity Testing
Li, Xilin; Chen, Si; Guo, Xiaoqing; Wu, Qiangen; Seo, Ji-Eun; Guo, Lei; Manjanatha, Mugimane G.; Zhou, Tong; Witt, Kristine L.; Mei, Nan
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SaveQuantitative comparison of in vitro genotoxicity between metabolically competent HepaRG cells and HepG2 cells using the high-throughput high-content CometChip assay
Seo, Ji-Eun; Tryndyak, Volodymyr; Wu, Qiangen; Dreval, Kostiantyn; Pogribny, Igor; Bryant, Matthew; Zhou, Tong; Robison, Timothy W.; Mei, Nan; Guo, Xiaoqing
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