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Vladimir Tolmachev

Department of Immunology

63H-index
606Paper Count
1.5WCitation Count
Published Papers 175
Publication Date
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Imaging of ROR1 expression in tumors using radiolabeled affibody molecules
errEuropean Journal of Nuclear Medicine and Molecular Imaging
IF7.6
err2026-08-01
err0
errOAAI
errCornelia Westerberg; Tianqi Xu; Maria Marth; Moeen Ud-Din; Russol Abushaia; Tilde Hagelin; Stefan Ståhl; Anna Orlova; Vladimir Tolmachev; John Löfblom; Anzhelika Vorobyeva
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The Use of Glycine-Containing Peptide-Based Chelators for Labeling with 99mTc Improves the Imaging Properties of EpCAM-Targeting Designed Ankyrin Repeat Ec1
errMolecular Pharmaceutics
IF4.5
err2026-03-04
err0
PREAI
errSergey Deyev; Anastasia Fominykh; Ruslan Varvashenya; Gleb Yanovich; Vitalina Bodenko; Evgenii Plotnikov; Mariia Tretyakova; Daria Eskova; Roman Zhelchan; Alexey Schulga; Elena Konovalova; Rustam Ziganshin; Anna Orlova; Mikhail Belousov; Vladimir Tolmachev; Mariia Larkina
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Phase I Clinical Study with the GRPR-Antagonist [99mTc]Tc-DB8 for SPECT Imaging of Prostate Cancer: Does the Injected Peptide Mass Make a Difference?
errPharmaceutics
IF5.5
err2026-03-03
err0
errOAAI
errAnna Orlova; Anastasia Rybina; Anna Medvedeva; Roman Zelchan; Olga Bragina; Liubov Tashireva; Maria Larkina; Ruslan Varvashenya; Nadejda Lushnikova; Panagiotis Kanellopoulos; Theodosia Maina; Berthold A. Nock; Vladimir Tolmachev; Vladimir Chernov
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Exploring the theranostic potential of two metabolically stable GRPR-targeting peptides labelled with Ga-68 for PET imaging
errEJNMMI Radiopharmacy and Chemistry
IF3.3
err2026-02-17
err0
errOAAI
errKarim Obeid; Ekaterina Bezverkhniaia; Vladimir Tolmachev; Anna Orlova; Panagiotis Kanellopoulos
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Efficient 68Ga Labeling of a B7-H3-Targeting Affibody Molecule via Acyclic Tris(hydroxypyridinone) Chelator: Effects on Biodistribution in a Preclinical Model
errInternational Journal of Molecular Sciences
IF4.9
err2026-02-10
err0
errOAAI
errVladimir Tolmachev; Amelinda Janice Herlina; Eleftherios Papalanis; Ekaterina A. Bezverkhniaia; Eva Ryer; Anna Orlova; Fredrik Y. Frejd; Maryam Oroujeni
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The position of 99mTc-HYNIC and the molecular design of the DARPin G3 constructs influence the selection of an imaging tracer to detect expression in HER2-expressing tumors
errJournal of Radioanalytical and Nuclear Chemistry
IF1.6
err2026-02-01
err0
PREAI
errLarkina, Maria; Varvashenya, Ruslan; Prach, Anastasia; Plotnikov, Evgenii; Tretyakova, Maria; Eskova, Daria; Bodenko, Vitalina; Yanovich, Gleb; Schulga, Alexey; Konovalova, Elena; Ziganshin, Rustam; Belousov, Mikhail; Chernov, Vladimir; Tolmachev, Vladimir; Deyev, Sergey
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Design of 3D spheroid models for drug-response studies of HER2-targeted radiopharmaceuticals
errBiomaterials Advances
IF6
err2025-11-22
err0
errOAAI
errIvan V. Zelepukin; Lisa Fulterer; Ahmed D. Elshazli; Amelinda J. Herlina; Vladimir Tolmachev
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Improving GRPR-targeting peptides for radiotheranostics application: insights from chelator modifications and α-methyl-L tryptophan substitution
errEJNMMI Radiopharmacy and Chemistry
IF3.3
err2025-11-13
err0
errOAAI
errKarim Obeid; Ekaterina Bezverkhniaia; Vladimir Tolmachev; Anna Orlova; Panagiotis Kanellopoulos
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Head-to-head evaluation of new generation GRPR-targeting theranostics labelled with Lu-177 / Ga-68
errNuclear Medicine and Biology
IF3
err2025-11-10
err0
PREAI
errPanagiotis Kanellopoulos; Karim Obeid; Ekaterina Bezverkhniaia; Athanasios Bitzios; Vladimir Tolmachev; Anna Orlova
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Comparative Preclinical Evaluation of the Tumor-Targeting Properties of Radioiodine and Technetium-Labeled Designed Ankyrin Repeat Proteins for Imaging of Epidermal Growth Factor Receptor Expression in Malignant Tumors
errInternational Journal of Molecular Sciences 2025, Vol. 26, Page 10609
IF4.9
err2025-10-31
err0
errOAAI
errMariia Larkina; Gleb Yanovich; Lutfi Aditya Hasnowo; Ruslan Varvashenya; Feruza Yuldasheva; Maria Tretyakova; Evgenii Plotnikov; Roman Zelchan; Alexey Schulga; Elena Konovalova; Rustam Ziganshin; Mikhail V. Belousov; Vladimir Tolmachev; Sergey M. Deyev
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LINKER MODIFICATIONS IN RADIOLABELED RM26-BASED ANTAGONISTS TO GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) IMPROVED TRACERS’ PHARMACOKINETICS
errEuropean Journal of Pharmaceutical Sciences
IF4.7
err2025-10-13
err0
errOAAI
errEkaterina Bezverkhniaia; Ayman Abouzayed; Panagiotis Kanellopoulos; Vladimir Tolmachev; Ulrika Rosenström; Anna Orlova
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An anti-CEA affibody showing high-definition staining in human pancreatic cancer tissue sections and selective tumor targeting in vivo
errTranslational Oncology
IF4.1
err2025-08-28
err0
PREAI
errJohan Nilvebrant; Carlos Fernández Moro; Eleftherios Papalanis; Masih Ostad Novin; Haozhong Ding; Ruonan Li; Maryam Oroujeni; Arun Selvam; Béla Bozóky; Torbjörn Gräslund; Timea Szekerczes; Tatiana Sandalova; Hugh Salter; Adnane Achour; Vladimir Tolmachev; Mikael Björnstedt; Per-Åke Nygren
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RM2 and DB15 analogues bearing [177Lu]Lu-DOTAGA via different linkers, as radiotherapeutics: a head-to-head comparative study
errEJNMMI Radiopharmacy and Chemistry
IF3.3
err2025-07-31
err0
errOAAI
errPanagiotis Kanellopoulos; Athanasios Bitzios; Ivan Zelepukin; Ekaterina Bezverkhniaia; Theodosia Maina; Berthold A. Nock; Vladimir Tolmachev; Anna Orlova
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Single-Photon Emission Computer Tomography Imaging of Prostate-Specific Membrane Antigen (PSMA) Expression in Prostate Cancer Patients Using a Novel Peptide-Based Probe [99mTc]Tc-BQ0413 with Picomolar Affinity to PSMA: A Phase I/II Clinical Study
errACS PHARMACOLOGY & TRANSLATIONAL SCIENCE
IF3.7
err2025-02-21
err0
errOAAI
errMedvedeva, A; Chernov, V; Larkina, M; Rybina, A; Zelchan, R; Bragina, O; Varvashenya, R; Zebzeeva, O; Bezverkhniaia, E; Tolmachev, V; Orlova, A
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Impact of Radiometal Chelates on In Vivo Visualization of Immune Checkpoint Protein Using Radiolabeled Affibody Molecules
errACS PHARMACOLOGY & TRANSLATIONAL SCIENCE
IF3.7
err2025-02-19
err0
errOAAI
errTolmachev, V; Papalanis, E; Bezverkhniaia, EA; Rosly, AH; Vorobyeva, A; Orlova, A; Carlqvist, M; Frejd, FY; Oroujeni, M
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Evaluation of ABD-Linked RM26 Conjugates for GRPR-Targeted Drug Delivery
errACS OMEGA
IF4.3
err2024-08-15
err1
errOAAI
errNagy, Abel; Abouzayed, Ayman; Kanellopoulos, Panagiotis; Landmark, Fredrika; Bezverkhniaia, Ekaterina; Tolmachev, Vladimir; Orlova, Anna; Karlstrom, Amelie Eriksson
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Evaluation of a novel 177Lu-labelled therapeutic Affibody molecule with a deimmunized ABD domain and improved biodistribution profile
errEuropean Journal of Nuclear Medicine and Molecular Imaging
IF7.6
err2024-07-15
err0
errOAAI
errLiu, Yongsheng; Oroujeni, Maryam; Liao, Yunqi; Vorobyeva, Anzhelika; Bodenko, Vitalina; Orlova, Anna; Konijnenberg, Mark; Carlqvist, Matilda; Wahlberg, Elisabet; Loftenius, Annika; Frejd, Fredrik Y.; Tolmachev, Vladimir
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Half-life extension via ABD-fusion leads to higher tumor uptake of an affibody-drug conjugate compared to PAS- and XTENylation.
errJOURNAL OF CONTROLLED RELEASE
IF11.5
err2024-06-01
err1
errOAAI
errZhang, Jie; Bodenko, Vitalina; Larkina, Maria; Bezverkhniaia, Ekaterina; Xu, Tianqi; Liao, Yunqi; Abouzayed, Ayman; Plotnikov, Evgenii; Tretyakova, Maria; Yuldasheva, Feruza; V. Belousov, Mikhail; Orlova, Anna; Tolmachev, Vladimir; Graslund, Torbjorn; Vorobyeva, Anzhelika
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Affibody PET Imaging of HER2-Expressing Cancers as a Key to Guide HER2-Targeted Therapy
errBIOMEDICINES
IF3.9
err2024-05-14
err8
errOAAI
errEissler, Nina; Altena, Renske; Alhuseinalkhudhur, Ali; Bragina, Olga; Feldwisch, Joachim; Wuerth, Guido; Loftenius, Annika; Brun, Nikolai; Axelsson, Rimma; Tolmachev, Vladimir; Sorensen, Jens; Frejd, Fredrik Y.
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Two Novel [68Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar11]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer
errACS OMEGA
IF4.3
err2024-04-10
err1
errOAAI
errKanellopoulos, Panagiotis; Bezverkhniaia, Ekaterina; Abouzayed, Ayman; Rosenstro''m, Ulrika; Tolmachev, Vladimir; Orlova, Anna
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Research Directions

No research directions
Co-authors
Cooperation Journals
E
Elisabetta Dejana
H-index: 127 · Papers: 567
C
Christer Betsholtz
H-index: 119 · Papers: 542
D
Dietmar Vestweber
H-index: 117 · Papers: 515
L
Lena Claesson‐Welsh
H-index: 97 · Papers: 376
L
Lars Lannfelt
H-index: 93 · Papers: 495
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