Not logged in Affimer-mediated locking of p21-activated kinase 5 in an intermediate activation state results in kinase inhibition Martin, Heather L.; Turner, Amy L.; Higgins, Julie; Tang, Anna A.; Tiede, Christian; Taylor, Thomas; Siripanthong, Sitthinon; Adams, Thomas L.; Manfield, Iain W.; Bell, Sandra M.; Morrison, Ewan E.; Bond, Jacquelyn; Trinh, Chi H.; Hurst, Carolyn D.; Knowles, Margaret A.; Bayliss, Richard W.; Tomlinson, Darren C. Share Save
Development of resistance to FGFR inhibition in urothelial carcinoma via multiple pathways in vitro Pettitt, Geoffrey A.; Hurst, Carolyn D.; Khan, Zubeda; McPherson, Helen R.; Dunning, Matthew C.; Alder, Olivia; Platt, Fiona M.; Black, Emma V., I; Burns, Julie E.; Knowles, Margaret A. Share Save
A transcriptional network of cell cycle dysregulation in noninvasive papillary urothelial carcinoma Warrick, Joshua I.; Knowles, Margaret A.; Hurst, Carolyn D.; Shuman, Lauren; Raman, Jay D.; Walter, Vonn; Putt, Jeffrey; Dyrskjot, Lars; Groeneveld, Clarice; Castro, Mauro A. A.; Robertson, A. Gordon; DeGraff, David J. Share Save
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Molecular profile of pure squamous cell carcinoma of the bladder identifies major roles for OSMR and YAP signalling Hurst, Carolyn D.; Cheng, Guo; Platt, Fiona M.; Alder, Olivia; Black, Emma V., I; Burns, Julie E.; Brown, Joanne; Jain, Sunjay; Roulson, Jo-An; Knowles, Margaret A. Share Save
Stage-stratified molecular profiling of non-muscle-invasive bladder cancer enhances biological, clinical, and therapeutic insight Hurst, Carolyn D.; Cheng, Guo; Platt, Fiona M.; Castro, Mauro A. A.; Marzouka, Nour-al-dain S.; Eriksson, Pontus; Black, Emma V., I; Alder, Olivia; Lawson, Andrew R. J.; Lindskrog, Sia, V; Burns, Julie E.; Jain, Sunjay; Roulson, Jo-An; Brown, Joanne C.; Koster, Jan; Robertson, A. Gordon; Martincorena, Inigo; Dyrskjot, Lars; Hoeglund, Mattias; Knowles, Margaret A. Share Save
An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer Lindskrog, Sia Viborg; Prip, Frederik; Lamy, Philippe; Taber, Ann; Groeneveld, Clarice S.; Birkenkamp-Demtroder, Karin; Jensen, Jorgen Bjerggaard; Strandgaard, Trine; Nordentoft, Iver; Christensen, Emil; Sokac, Mateo; Birkbak, Nicolai J.; Maretty, Lasse; Hermann, Gregers G.; Petersen, Astrid C.; Weyerer, Veronika; Grimm, Marc-Oliver; Horstmann, Marcus; Sjodahl, Gottfrid; Hoglund, Mattias; Steiniche, Torben; Mogensen, Karin; de Reynies, Aurelien; Nawroth, Roman; Jordan, Brian; Lin, Xiaoqi; Dragicevic, Dejan; Ward, Douglas G.; Goel, Anshita; Hurst, Carolyn D.; Raman, Jay D.; Warrick, Joshua, I; Segersten, Ulrika; Sikic, Danijel; van Kessel, Kim E. M.; Maurer, Tobias; Meeks, Joshua J.; DeGraff, David J.; Bryan, Richard T.; Knowles, Margaret A.; Simic, Tatjana; Hartmann, Arndt; Zwarthoff, Ellen C.; Malmstrom, Per-Uno; Malats, Nuria; Real, Francisco X.; Dyrskjot, Lars Share Save
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TRPA1-FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p Berrout, Jonathan; Kyriakopoulou, Eleni; Moparthi, Lavanya; Hogea, Alexandra S.; Berrout, Liza; Ivan, Cristina; Lorger, Mihaela; Boyle, John; Peers, Chris; Muench, Stephen; Gomez, Jacobo Elies; Hu, Xin; Hurst, Carolyn; Hall, Thomas; Umamaheswaran, Sujanitha; Wesley, Laura; Gagea, Mihai; Shires, Michael; Manfield, Iain; Knowles, Margaret A.; Davies, Simon; Suhling, Klaus; Gonzalez, Yurema Teijeiro; Carragher, Neil; Macleod, Kenneth; Abbott, N. Joan; Calin, George A.; Gamper, Nikita; Zygmunt, Peter M.; Timsah, Zahra Share Save
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The genomic landscape of non-muscle-invasive bladder cancer: implications for molecular classification and treatment Hurst, Carolyn D.; Alder, Olivia; Platt, Fiona M.; Droop, Alastair; Stead, Lucy F.; Burns, Julie E.; Burghel, George J.; Jain, Sunjay; Klimczak, Leszek J.; Lindsay, Helen; Roulson, Jo-An; Taylor, Claire F.; Thygesen, Helene; Cameron, Angus J.; Ridley, Anne J.; Mott, Helene R.; Gordenin, Dmitry A.; Knowles, Margaret A. Share Save
Tumor heterogeneity of fibroblast growth factor receptor 3 (FGFR3) mutations in invasive bladder cancer: implications for perioperative anti-FGFR3 treatment Pouessel, D.; Neuzillet, Y.; Mertens, L. S.; van der Heijden, M. S.; de Jong, J.; Sanders, J.; Peters, D.; Leroy, K.; Manceau, A.; Maille, P.; Soyeux, P.; Moktefi, A.; Semprez, F.; Vordos, D.; de la Taille, A.; Hurst, C. D.; Tomlinson, D. C.; Harnden, P.; Bostrom, P. J.; Mirtti, T.; Horenblas, S.; Loriot, Y.; Houede, N.; Chevreau, C.; Beuzeboc, P.; Shariat, S. F.; Sagalowsky, A. I.; Ashfaq, R.; Burger, M.; Jewett, M. A. S.; Zlotta, A. R.; Broeks, A.; Bapat, B.; Knowles, M. A.; Lotan, Y.; van der Kwast, T. H.; Culine, S.; Allory, Y.; van Rhijn, B. W. G. Share Save
TERT Core Promotor Mutations in Early-Onset Bladder Cancer Giedl, Johannes; Rogler, Anja; Wild, Andreas; Riener, Marc-Oliver; Filbeck, Thomas; Burger, Maximilian; Ruemmele, Petra; Hurst, Carolyn; Knowles, Margaret; Hartmann, Arndt; Zinnall, Ulrike; Stoehr, Robert Share Save
Frequency of TERT Promoter Mutations in Prostate Cancer Stoehr, Robert; Taubert, Helge; Zinnall, Ulrike; Giedl, Johannes; Gaisa, Nadine T.; Burger, Maximilian; Ruemmele, Petra; Hurst, Carolyn D.; Knowles, Margaret A.; Wullich, Bernd; Hartmann, Arndt Share Save
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Genome-wide association study yields variants at 20p12.2 that associate with urinary bladder cancer Rafnar, Thorunn; Sulem, Patrick; Thorleifsson, Gudmar; Vermeulen, Sita H.; Helgason, Hannes; Saemundsdottir, Jona; Gudjonsson, Sigurjon A.; Sigurdsson, Asgeir; Stacey, Simon N.; Gudmundsson, Julius; Johannsdottir, Hrefna; Alexiusdottir, Kristin; Petursdottir, Vigdis; Nikulasson, Sigfus; Geirsson, Gudmundur; Jonsson, Thorvaldur; Aben, Katja K. H.; Grotenhuis, Anne J.; Verhaegh, Gerald W.; Dudek, Aleksandra M.; Witjes, J. Alfred; van der Heijden, Antoine G.; Vrieling, Alina; Galesloot, Tessel E.; De Juan, Ana; Panadero, Angeles; Rivera, Fernando; Hurst, Carolyn; Bishop, D. Timothy; Sak, Sei C.; Choudhury, Ananya; Teo, Mark T. W.; Arici, Cecilia; Carta, Angela; Toninelli, Elena; de Verdier, Petra; Rudnai, Peter; Gurzau, Eugene; Koppova, Kvetoslava; van der Keur, Kirstin A.; Lurkin, Irene; Goossens, Mieke; Kellen, Eliane; Guarrera, Simonetta; Russo, Alessia; Critelli, Rossana; Sacerdote, Carlotta; Vineis, Paolo; Krucker, Clementine; Zeegers, Maurice P.; Gerullis, Holger; Ovsiannikov, Daniel; Volkert, Frank; Hengstler, Jan G.; Selinski, Silvia; Magnusson, Olafur T.; Masson, Gisli; Kong, Augustine; DanielGudbjartsson; Lindblom, Annika; Zwarthoff, Ellen; Porru, Stefano; Golka, Klaus; Buntinx, Frank; Matullo, Giuseppe; Kumar, Rajiv; Mayordomo, Jose I.; Steineck, D. Gunnar; Kiltie, Anne E.; Jonsson, Eirikur; Radvanyi, Francois; Knowles, Margaret A.; Thorsteinsdottir, Unnur; Stefansson, Kari Share Save
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