Not logged in RAS Pathway Inhibitors Combined with Targeted Agents Are Active in Patient-Derived Spheroids with Oncogenic KRAS Variants from Multiple Cancer Types Davoudi, Zahra; Dexheimer, Thomas S.; Coussens, Nathan P.; Silvers, Thomas; Fox, Raymond G.; Kemp, Samantha B.; Juneja, Poorva; Morris, Joel; Hollingshead, Melinda G.; Takebe, Naoko; Doroshow, James H.; Teicher, Beverly A. Share Save
Combinatorial screen with apoptosis pathway targeted agents alrizomadlin, pelcitoclax, and dasminapant in multi-cell type tumor spheroids Coussens, Nathan P.; Dexheimer, Thomas S.; Silvers, Thomas; Sanchez, Phillip R.; Chen, Li; Hollingshead, Melinda G.; Takebe, Naoko; Doroshow, James H.; Teicher, Beverly A. Share Save
Share Save
A Pan-Cancer Patient-Derived Xenograft Histology Image Repository with Genomic and Pathologic Annotations Enables Deep Learning Analysis White, Brian S.; Woo, Xing Yi; Koc, Soner; Sheridan, Todd; Neuhauser, Steven B.; Wang, Shidan; Evrard, Yvonne A.; Chen, Li; Pour, Ali Foroughi; Landua, John D.; Mashl, R. Jay; Davies, Sherri R.; Fang, Bingliang; Rosa, Maria Gabriela; Evans, Kurt W.; Bailey, Matthew H.; Chen, Yeqing; Xiao, Min; Rubinstein, Jill C.; Sanderson, Brian J.; Lloyd, Michael W.; Domanskyi, Sergii; Dobrolecki, Lacey E.; Fujita, Maihi; Fujimoto, Junya; Xiao, Guanghua; Fields, Ryan C.; Mudd, Jacqueline L.; Xu, Xiaowei; Hollingshead, Melinda G.; Jiwani, Shahanawaz; Acevedo, Saul; Davis-Dusenbery, Brandi N.; Robinson, Peter N.; Moscow, Jeffrey A.; Doroshow, James H.; Mitsiades, Nicholas; Kaochar, Salma; Pan, Chong-xian; Carvajal-Carmona, Luis G.; Welm, Alana L.; Welm, Bryan E.; Govindan, Ramaswamy; Li, Shunqiang; Davies, Michael A.; Roth, Jack A.; Meric-Bernstam, Funda; Xie, Yang; Herlyn, Meenhard; Ding, Li; Lewis, Michael T.; Bult, Carol J.; Dean II, Dennis A.; Chuang, Jeffrey H. Share Save
MTX-531, a first-in-class pan-PI3K inhibitor spares hyperinsulinemia yielding durable tumor regressions and resilience to adaptive resistance Whitehead, Christopher E.; Ziemke, Elizabeth K.; Frankowski-McGregor, Christy L.; Mumby, Rachel A.; Chung, June; Li, Jinju; Osher, Nathaniel; Coker, Oluwadara; Norris, Michelle; Kopetz, Scott; Baladandayuthapani, Veera; Hollingshead, Melinda; Verma, Sharad; Sebolt-Leopold, Judith S. Share Save
Integrated proteogenomic analysis for the NCI patient-derived cancer model repository Wu, Peter I.; Chen, Li; Kotliarov, Yuri; Fang, Jianwen; Zhao, Yingdong; Evrard, Yvonne; Chen, Lijun; Jiwani, Shahanawaz; Das, Biswajit; Karlovich, Chris A.; Zhang, Hui; McShane, Lisa; Hollingshead, Melinda G.; Williams, Mickey; Doroshow, James H. Share Save
Cholangiocarcinoma patient-derived models in the NCI Patient-Derived Models Repository Evrard, Yvonne A.; Timme, Cindy R.; Das, Biswajit; Bliss, Gareth; Bonomi, Carrie; Border, Carley; Chang, Ting-Chia; Chen, Alice; Chen, Li; Crespo-Eugeni, Michelle A.; Cooper, Kevin; Czarra, Natalie; Czernia, Isabella; Dougherty, Kelly; Gibson, Marion; Grinnage-Pulley, Tara; Jiwani, Shahanawaz; Kalmbach, Keegan; Karlovich, Chris A.; McGlynn, Chelsea; Mullendore, Michael; Murphy, Matthew; Pauly, Rini; Plater, Kevin; Steed, Jessica; Stockwin, Luke; Uzelac, Shannon; Wu, Peter I-Fan; Newton, Dianne L.; Williams, P. Mickey; Hollingshead, Melinda G.; Doroshow, James H. Share Save
Expanding reported molecular characteristics for the NCI Patient-Derived Models Repository Timme, Cindy R.; Evrard, Yvonne A.; Das, Biswajit; Chang, Ting-Chia; Chen, Alice; Chen, Li; Crespo-Eugeni, Michelle A.; Jiwani, Shahanawaz; Karlovich, Chris A.; Pauly, Rini; Wu, Peter I-Fan; Newton, Dianne L.; Williams, P. Mickey; Hollingshead, Melinda G.; Doroshow, James H. Share Save
Genomic landscape and stability of preclinical models in NCI's patient-derived models repository Chang, Ting-Chia; Das, Biswajit; Chen, Li; Wu, Peter I-Fan; Evrard, Yvonne A.; Pauly, Rini; Newton, Dianne L.; Jiwani, Shahanawaz; Alcoser, Sergio Y.; Stockwin, Luke H.; Camalier, Corinne E.; Forbes, Tomas; Nair, Nikitha; Chapman, Alyssa; Dutko, Lindsay; Mullendore, Michael; Grinnage-Pulley, Tara; Klarmann, Kimberly; Miller, Sarah B.; Karlovich, Chris A.; Chen, Alice P.; Williams, P. Mickey; Hollingshead, Melinda G.; Doroshow, James H. Share Save
Share Save
Biochemical inhibition profiles of 370 wild type human kinases provide a basis for selecting alternative combinations of EGFR and VEGFR inhibitors Coussens, Nathan P.; Dexheimer, Thomas S.; Silvers, Thomas; Uzelac, Shannon; Georgius, Kyle; Carter, John; Shearer, Tia; Rao, Rekha; Gray, Karen; Srivastava, Apurva K.; Kinders, Robert J.; Evrard, Yvonne A.; Hollingshead, Melinda G.; Morris, Joel; Moscow, Jeffrey A.; Parchment, Ralph E.; Teicher, Beverly A.; Doroshow, James H. Share Save
Combination therapies in matched 3D in vitro and in vivo preclinical models of rare and recalcitrant cancers from the National Cancer Institute's Patient-Derived Models Repository Dexheimer, Thomas S.; Silvers, Thomas; Delosh, Rene; Reinhart, Russell; Ogle, Chad; Davoudi, Zahra; Jones, Eric; Trail, Debbie; Carter, John; Mills, Justine; Georgius, Kyle; Stotler, Howard; Norris, Michelle; Uzelac, Shannon; Borgel, Suzanne; Minor, Tiffanie; Stockwin, Luke; Mullendore, Michael; Plater, Kevin; Kalmbach, Keegan; Steed, Jessica; Murphy, Matthew; Bliss, Gareth; Bonomi, Carrie; Dougherty, Kelly; Gibson, Marion; Cooper, Kevin; Newton, Dianne; Timme, Cindy R.; Evrard, Yvonne A.; Hollingshead, Melinda G.; Coussens, Nathan P.; Parchment, Ralph E.; Doroshow, James H.; Teicher, Beverly A. Share Save
Molecular subclassification of NCI PDMR breast cancer models using PAM50 gene expression signature Wu, Peter I.; Dutko, Lindsay; Jiwani, Shahanawaz; Chen, Li; Das, Biswajit; Chang, Ting-Chia; Evrard, Yvonne A.; Karlovich, Chris A.; Chapman, Alyssa; Fullmer, Brandie; Hayes, Ashley; Thornton, Ruth; Nair, Nikitha; Benauer, Kelly; Rivera, Gloryvee; Forbes, Thomas; Carter, John; Borgel, Suzanne; Miner, Tiffanie; McGlynn, Chelsea; Mills, Justine; Uzelac, Shannon; Shearer, Tia; Hicks, Lauren; Norris, Michelle; Border, Carley; Alcoser, Sergio; Walsh, Thomas; Mullendore, Michael; Eugeni, Michelle; Newton, Dianne; Hollingshead, Melinda G.; Williams, P. M.; Doroshow, James H. Share Save
A pan-cancer PDX histology image repository with genomic and pathological annotations for deep learning analysis White, Brian S.; Woo, Xing Yi; Koc, Soner; Sheridan, Todd; Neuhauser, Steven B.; Wang, Shidan; Evrard, Yvonne A.; Landua, John David; Mashl, R. Jay; Davies, Sherri R.; Fang, Bingliang; Raso, Maria Gabriela; Evans, Kurt W.; Bailey, Matthew H.; Chen, Yeqing; Xiao, Min; Rubinstein, Jill; Pour, Ali Foroughi; Dobrolecki, Lacey Elizabeth; Fujita, Maihi; Fujimoto, Junya; Xiao, Guanghua; Fields, Ryan C.; Mudd, Jacqueline L.; Xu, Xiaowei; Hollingshead, Melinda G.; Jiwani, Shahanawaz; Consortium, Pdxnet; Wallace, Tiffany A.; Moscow, Jeffrey A.; Doroshow, James H.; Mitsiades, Nicholas; Kaochar, Salma; Pan, Chong-Xian; Chen, Moon S.; Carvajal-Carmona, Luis G.; Welm, Alana L.; Welm, Bryan E.; Govindan, Ramaswamy; Li, Shunqiang; Davies, Michael A.; Roth, Jack A.; Meric-Bernstam, Funda; Xie, Yang; Herlyn, Meenhard; Ding, Li; Lewis, Michael T.; Bolt, Carol J.; Dean, Dennis A.; Chuang, Jeffrey H. Share Save
NCI patient derived models repository: PDX, organoid and cell lines from the same patient - bridging the translational pipeline Evrard, Yvonne A.; Chen, Li; Alcoser, Sergio; Bliss, Gareth; Bonomi, Carrie; Borgel, Suzanne; Carter, John; Chang, Ting-Chia; Chen, Alice; Cooper, Kevin; Das, Biswajit; Dougherty, Kelly; Dutko, Lindsay; Gibson, Marion; Ahalt-Gottholm, Michelle M.; Grinnage-Pulley, Tara; Kalmbach, Keegan; Karlovich, Chris; Klarmann, Kimberly; Jiwani, Shahanawaz; Miner, Tiffanie; Mullendore, Michael; Murphy, Matthew; Plater, Kevin; Rivera, Gloryvee; Steed, Jessica; Stockwin, Luke; Timme, Cindy R.; Newton, Dianne L.; Williams, Paul Mickey; Hollingshead, Melinda G.; Doroshow, James H. Share Save
Chromosomal aneuploidy, whole-genome doubling and mutational signatures in NCI PDMR models Chen, Li; Das, Biswajit; Chang, Ting-Chia; Evrard, Yvonne A.; Karlovich, Chris A.; Chapman, Alyssa; Fullmer, Brandie; Hayes, Ashley; Thornton, Ruth; Nair, Nikitha; Jiwani, Shahanawaz; Dutko, Lindsay; Benauer, Kelly; Rivera, Gloryvee; Camalier, Corinne; Carter, John; Borgel, Suzanne; Miner, Tiffanie; McGlynn, Chelsea; Mills, Justine; Uzelac, Shannon; Shearer, Tia; Hicks, Lauren; Norris, Michelle; Border, Carley; Alcoser, Sergio; Walsh, Thomas; Mullendore, Michael; Eugeni, Michelle; Newton, Dianne; Hollingshead, Melinda G.; Williams, P. Mickey; Doroshow, James H. Share Save
Comparing twenty-two matched patient-derived cell lines developed from either patient, PDX, or organoid tumor cell material Timme, Cindy R.; Chang, Ting-Chia; Alcoser, Sergio Y.; Bliss, Gareth; Bonomi, Carrie; Borgel, Suzanne; Carter, John; Chen, Alice; Chen, Li; Cooper, Kevin; Das, Biswajit; Dougherty, Kelly; Dutko, Lindsay; Gibson, Marion; Gottholm-Ahalt, Michelle M.; Grinnage-Pulley, Tara; Jiwani, Shahanawaz; Kalmbach, Keegan; Karlovich, Chris; Klarmann, Kimberly; Chase, Tiffanie; Mullendore, Michael; Murphy, Matthew; Plater, Kevin; Rivera, Gloryvee; Steed, Jessica; Stockwin, Luke; Evrard, Yvonne A.; Williams, Mickey; Newton, Dianne L.; Hollingshead, Melinda G.; Doroshow, James H. Share Save
Exploiting embryonic niche conditions to grow Wilms tumor blastema in culture Wojcik, Heather M.; Lovvorn III, Harold N.; Hollingshead, Melinda; Pierce, Janene; Stotler, Howard; Murphy, Andrew J.; Borgel, Suzanne; Phelps, Hannah M.; Correa, Hernan; Perantoni, Alan O. Share Save
3′-[18F]fluoro-3′-deoxythymidine ([18F]FLT) Positron Emission Tomography as an In Vivo Biomarker of inhibition of CDK 4/6-Rb pathway by Palbociclib in a patient derived bladder tumor Tatum, James L.; Kalen, Joseph D.; Jacobs, Paula M.; Riffle, Lisa A.; James, Amy; Thang, Lai; Sanders, Chelsea; Hollingshead, Melinda G.; Basuli, Falguni; Shi, Jianfeng; Doroshow, James H. Share Save
Share Save
.png){kind=icon}
.png){kind=icon}
Not logged in.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}