Not logged in Single- cell analysis of treatment- resistant prostate cancer: Implications of cell state changes for cell surface antigen- targeted therapies Zaidi, Samir; Park, Jooyoung; Chan, Joseph M.; Roudier, Martine P.; Zhao, Jimmy L.; Gopalan, Anuradha; Wadosky, Kristine M.; Patel, Radhika A.; Sayar, Erolcan; Karthaus, Wouter R.; Kates, D. Henry; Chaudhary, Ojasvi; Xu, Tianhao; Masilionis, Ignas; Mazutis, Linas; Chaligne, Ronan; Obradovic, Aleksandar; Linkov, Irina; Barlas, Afsar; Jungbluth, Achim A.; Rekhtman, Natasha; Silber, Joachim; Manova-Todorova, Katia; Watson, Philip A.; True, Lawrence D.; Morrissey, Colm; Scher, Howard I.; Rathkopf, Dana E.; Morris, Michael J.; Goodrich, David W.; Choi, Jungmin; Nelson, Peter S.; Haffner, Michael C.; Sawyers, Charles L. Share Save
FLT1 activation in cancer cells promotes PARP-inhibitor resistance in breast cancer Tai, Yifan; Chow, Angela; Han, Seoyoung; Coker, Courtney; Ma, Wanchao; Gu, Yifan; Navarro, Valeria Estrada; Kandpal, Manoj; Hibshoosh, Hanina; Kalinsky, Kevin; Manova-Todorova, Katia; Safonov, Anton; Walsh, Elaine M.; Robson, Mark; Norton, Larry; Baer, Richard; Merghoub, Taha; Biswas, Anup K.; Acharyya, Swarnali Share Save
Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation Rodina, Anna; Xu, Chao; Digwal, Chander S. S.; Joshi, Suhasini; Patel, Yogita; Santhaseela, Anand R. R.; Bay, Sadik; Merugu, Swathi; Alam, Aftab; Yan, Pengrong; Yang, Chenghua; Roychowdhury, Tanaya; Panchal, Palak; Shrestha, Liza; Kang, Yanlong; Sharma, Sahil; Almodovar, Justina; Corben, Adriana; Alpaugh, Mary L. L.; Modi, Shanu; Guzman, Monica L. L.; Fei, Teng; Taldone, Tony; Ginsberg, Stephen D. D.; Erdjument-Bromage, Hediye; Neubert, Thomas A. A.; Manova-Todorova, Katia; Tsou, Meng-Fu Bryan; Young, Jason C. C.; Wang, Tai; Chiosis, Gabriela Share Save
ERG-driven luminal prostate cancers emerge from Ck5+/Nkx3.1+basal cells Feng, Weiran; Ladewig, Erik; Salsabeel, Nazifa; Zhao, Huiyong; Lee, Young Sun; Gopalan, Anuradha; Luo, Hanzhi; Kang, Wenfei; Fan, Ning; Rosiek, Eric; Masilionis, Ignas; Manova-Todorova, Katia; Chaligne, Ronan; de Stanchina, Elisa; Carver, Brett S.; Chen, Yu; Gao, Dong; Leslie, Christina S.; Sawyers, Charles L. Share Save
Intratumoral Escherichia is associated with response to single-agent immune checkpoint inhibition in patients with advanced non-small cell lung cancer Elkrief, Arielle; Bowman, Anita S.; Bektas, Ayyuce Begum; Kang, Wenfei; Manova-Todorova, Katia; Egger, Jacklynn V.; Rizvi, Hira; Kelly, Daniel; Chan, Eric; Rosiek, Eric; Ning, Fan; Riely, Gregory J.; Villalonga, Alvaro Quintanal; Dogan, Snjezana; Bhanot, Umesh; Gonen, Mithat; Hellmann, Matthew D.; Schoenfeld, Adam J.; Rudin, Charles M.; Ladanyi, Marc; Vanderbilt, Chad M. Share Save
Allosteric interactions prime androgen receptor dimerization and activation Wasmuth, Elizabeth V.; Vanden Broeck, Arnaud; LaClair, Justin R.; Hoover, Elizabeth A.; Lawrence, Kayla E.; Paknejad, Navid; Pappas, Kyrie; Matthies, Doreen; Wang, Biran; Feng, Weiran; Watson, Philip A.; Zinder, John C.; Karthaus, Wouter R.; de la Cruz, M. Jason; Hite, Richard K.; Manova-Todorova, Katia; Yu, Zhiheng; Weintraub, Susan T.; Klinge, Sebastian; Sawyers, Charles L. Share Save
Targeting S100A9-ALDH1A1-Retinoic Acid Signaling to Suppress Brain Relapse in EGFR-Mutant Lung Cancer Biswas, Anup Kumar; Han, Seoyoung; Tai, Yifan; Ma, Wanchao; Coker, Courtney; Quinn, S. Aidan; Shakri, Ahmad Rushdi; Zhong, Timothy James; Scholze, Hanna; Lagos, Galina G.; Mela, Angeliki; Manova-Todorova, Katia; de Stanchina, Elisa; Ferrando, Adolfo A.; Mendelsohn, Cathy; Canoll, Peter; Yu, Helena A.; Paik, Paul K.; Saqi, Anjali; Shu, Catherine A.; Kris, Mark G.; Massague, Joan; Acharyya, Swarnali Share Save
Therapeutic targeting of SLC6A8 creatine transporter suppresses colon cancer progression and modulates human creatine levels Kurth, Isabel; Yamaguchi, Norihiro; Andreu-Agullo, Celia; Tian, Helen S.; Sridhar, Subhasree; Takeda, Shugaku; Gonsalves, Foster C.; Loo, Jia Min; Barlas, Afsar; Manova-Todorova, Katia; Busby, Robert; Bendell, Johanna C.; Strauss, James; Fakih, Marwan; McRee, Autumn J.; Hendifar, Andrew E.; Rosen, Lee S.; Cercek, Andrea; Wasserman, Robert; Szarek, Michael; Spector, Scott L.; Raza, Syed; Tavazoie, Masoud F.; Tavazoie, Sohail F. Share Save
KRAS mutant rectal cancer cells interact with surrounding fibroblasts to deplete the extracellular matrix Kim, Jin K.; Marco, Michael R.; Choi, Seo-Hyun; Qu, Xuan; Chen, Chin-Tung; Elkabets, Moshe; Fairchild, Lauren; Chow, Oliver; Barriga, Francisco M.; Dow, Lukas E.; O'Rourke, Kevin; Szeglin, Bryan; Yarilin, Dmitry; Fujisawa, Sho; Manova-Todorova, Katia; Paty, Philip B.; Shia, Jinru; Leslie, Christina; Smith, J. Joshua; Lowe, Scott; Pelossof, Raphael; Sanchez-Vega, Francisco; Garcia-Aguilar, Julio Share Save
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L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer (vol 1, pg 28, 2020) Ganesh, Karuna; Basnet, Harihar; Kaygusuz, Yasemin; Laughney, Ashley M.; He, Lan; Sharma, Roshan; O'Rourke, Kevin P.; Reuter, Vincent P.; Huang, Yun-Han; Turkekul, Mesruh; Er, Ekrem Emrah; Masilionis, Ignas; Manova-Todorova, Katia; Weiser, Martin R.; Saltz, Leonard B.; Garcia-Aguilar, Julio; Koche, Richard; Lowe, Scott W.; Pe'er, Dana; Shia, Jinru; Massague, Joan Share Save
Spatial mapping of the collagen distribution in human and mouse tissues by force volume atomic force microscopy Calo, Annalisa; Romin, Yevgeniy; Srouji, Rami; Zambirinis, Constantinos P.; Fan, Ning; Santella, Anthony; Feng, Elvin; Fujisawa, Sho; Turkekul, Mesruh; Huang, Sharon; Simpson, Amber L.; D'Angelica, Michael; Jarnagin, William R.; Manova-Todorova, Katia Share Save
gC1qR/HABP1/p32 Is a Potential New Therapeutic Target Against Mesothelioma Peerschke, Ellinor; Stier, Kenneth; Li, Xiaoyu; Kandov, Evelyn; de Stanchina, Elisa; Chang, Qing; Xiong, Yuquan; Manova-Todorova, Katia; Fan, Ning; Barlas, Afsar; Ghebrehiwet, Berhane; Adusumilli, Prasad S. Share Save
The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction Inda, Maria Carmen; Joshi, Suhasini; Wang, Tai; Bolaender, Alexander; Gandu, Srinivasa; Koren, John, III; Che, Alicia Yue; Taldone, Tony; Yan, Pengrong; Sun, Weilin; Uddin, Mohammad; Panchal, Palak; Riolo, Matthew; Shah, Smit; Barlas, Afsar; Xu, Ke; Chan, Lon Yin L.; Gruzinova, Alexandra; Kishinevsky, Sarah; Studer, Lorenz; Fossati, Valentina; Noggle, Scott A.; White, Julie R.; de Stanchina, Elisa; Sequeira, Sonia; Anthoney, Kyle H.; Steele, John W.; Manova-Todorova, Katia; Patil, Sujata; Dunphy, Mark P.; Pillarsetty, NagaVaraKishore; Pereira, Ana C.; Erdjument-Bromage, Hediye; Neubert, Thomas A.; Rodina, Anna; Ginsberg, Stephen D.; Garcia, Natalia De Marco; Luo, Wenjie; Chiosis, Gabriela Share Save
L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer Ganesh, Karuna; Basnet, Harihar; Kaygusuz, Yasemin; Laughney, Ashley M.; He, Lan; Sharma, Roshan; O'Rourke, Kevin P.; Reuter, Vincent P.; Huang, Yun-Han; Turkekul, Mesruh; Er, Ekrem Emrah; Masilionis, Ignas; Manova-Todorova, Katia; Weiser, Martin R.; Saltz, Leonard B.; Garcia-Aguilar, Julio; Koche, Richard; Lowe, Scott W.; Pe'er, Dana; Shia, Jinru; Massague, Joan Share Save
A rectal cancer organoid platform to study individual responses to chemoradiation Ganesh, Karuna; Wu, Chao; O'Rourke, Kevin P.; Szeglin, Bryan C.; Zheng, Youyun; Sauve, Charles-Etienne Gabriel; Adileh, Mohammad; Wasserman, Isaac; Marco, Michael R.; Kim, Amanda S.; Shady, Maha; Sanchez-Vega, Francisco; Karthaus, Wouter R.; Won, Helen H.; Choi, Seo-Hyun; Pelossof, Raphael; Barlas, Afsar; Ntiamoah, Peter; Pappou, Emmanouil; Elghouayel, Arthur; Strong, James S.; Chen, Chin-Tung; Harris, Jennifer W.; Weiser, Martin R.; Nash, Garrett M.; Guillem, Jose G.; Wei, Iris H.; Kolesnick, Richard N.; Veeraraghavan, Harini; Ortiz, Eduardo J.; Petkovska, Iva; Cercek, Andrea; Manova-Todorova, Katia O.; Saltz, Leonard B.; Lavery, Jessica A.; DeMatteo, Ronald P.; Massague, Joan; Paty, Philip B.; Yaeger, Rona; Chen, Xi; Patil, Sujata; Clevers, Hans; Berger, Michael F.; Lowe, Scott W.; Shia, Jinru; Romesser, Paul B.; Dow, Lukas E.; Garcia-Aguilar, Julio; Sawyers, Charles L.; Smith, J. Joshua Share Save
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Single-dose radiotherapy disables tumor cell homologous recombination via ischemia/reperfusion injury Bodo, Sahra; Campagne, Cecile; Thin, Tin Htwe; Higginson, Daniel S.; Vargas, H. Alberto; Hua, Guoqiang; Fuller, John D.; Ackerstaff, Ellen; Russell, James; Zhang, Zhigang; Klingler, Stefan; Cho, HyungJoon; Kaag, Matthew G.; Mazaheri, Yousef; Rimner, Andreas; Manova-Todorova, Katia; Epel, Boris; Zatcky, Joan; Cleary, Cristian R.; Rao, Shyam S.; Yamada, Yoshiya; Zelefsky, Michael J.; Halpern, Howard J.; Koutcher, Jason A.; Cordon-Cardo, Carlos; Greco, Carlo; Haimovitz-Friedman, Adriana; Sala, Evis; Powell, Simon N.; Kolesnick, Richard; Fuks, Zvi Share Save
Technical Note: Scintillation well counters and particle counting digital autoradiography devices can be used to detect activities associated with genomic profiling adequacy of biopsy specimens obtained after a low activity 18F-FDG injection Kirov, Assen S.; Fanchon, Louise M.; Seiter, Daniel; Czmielewski, Christian; Russell, James; Dogan, Snjezana; Carlin, Sean; Pinker-Domenig, Katja; Yorke, Ellen; Schmidtlein, C. Ross; Boyko, Vitaly; Fujisawa, Sho; Manova-Todorova, Katia; Zanzonico, Pat; Dauer, Lawrence; Deasy, Joseph O.; Humm, John L.; Solomon, Stephen Share Save
Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation Zhang, Haiying; Freitas, Daniela; Kim, Han Sang; Fabijanic, Kristina; Li, Zhong; Chen, Haiyan; Mark, Milica Tesic; Molina, Henrik; Martin, Alberto Benito; Bojmar, Linda; Fang, Justin; Rampersaud, Sham; Hoshino, Ayuko; Matei, Irina; Kenific, Candia M.; Nakajima, Miho; Mutvei, Anders Peter; Sansone, Pasquale; Buehring, Weston; Wang, Huajuan; Jimenez, Juan Pablo; Cohen-Gould, Leona; Paknejad, Navid; Brendel, Matthew; Manova-Todorova, Katia; Magalhaes, Ana; Ferreira, Jose Alexandre; Osorio, Hugo; Silva, Andre M.; Massey, Ashish; Cubillos-Ruiz, Juan R.; Galletti, Giuseppe; Giannakakou, Paraskevi; Cuervo, Ana Maria; Blenis, John; Schwartz, Robert; Brady, Mary Sue; Peinado, Hector; Bromberg, Jacqueline; Matsui, Hiroshi; Reis, Celso A.; Lyden, David Share Save
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