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Luke Isbel

Adelaide University

14H-index
41Paper Count
1.1KCitation Count
Published Papers 14
Publication Date
DesignMaster: A Multi-Conditional Diffusion Framework for Rational PROTAC Design
err2026-09-24
err0
errOAAI
errBinze Shi; Yi Hao; Jie Liu; Tong Pan; Luke Isbel; Michael Roy; Ashley P Ng; Xuequn Shang; Fuyi Li; null; null
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Chromatin-dependent motif syntax defines differentiation trajectories
err2025-08-07
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errOAAI
errSevi Durdu; Murat Iskar; Luke Isbel; Leslie Hoerner; Christiane Wirbelauer; Lukas Burger; Daniel Hess; Vytautas Iesmantavicius; Dirk Schübeler
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Nucleosomes specify co-factor access to p53
err2025-07-25
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PREAI
errDeyasini Chakraborty; Colby R. Sandate; Luke Isbel; Georg Kempf; Joscha Weiss; Simone Cavadini; Lukas Kater; Jan Seebacher; Zuzanna Kozicka; Lisa Stoos; Ralph S. Grand; Dirk Schübeler; Alicia K. Michael; Nicolas H. Thomä
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Accurate PROTAC-targeted degradation prediction with DegradeMaster
err2025-07-01
err4
errOAAI
errLiu, Jie; Roy, Michael J.; Isbel, Luke; Li, Fuyi
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Readout of histone methylation by Trim24 locally restricts chromatin opening by p53
err2023-06-29
err16
errOAAI
errIsbel, Luke; Iskar, Murat; Durdu, Sevi; Weiss, Joscha; Grand, Ralph S.; Hietter-Pfeiffer, Eric; Kozicka, Zuzanna; Michael, Alicia K.; Burger, Lukas; Thomae, Nicolas H.; Schubeler, Dirk
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ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers
err2023-01-05
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errOAAI
errYelagandula, Ramesh; Stecher, Karin; Novatchkova, Maria; Michetti, Luca; Michlits, Georg; Wang, Jingkui; Hofbauer, Pablo; Vainorius, Gintautas; Pribitzer, Carina; Isbel, Luke; Mendjan, Sasha; Schuebeler, Dirk; Elling, Ulrich; Brennecke, Julius; Bell, Oliver
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CG dinucleotides enhance promoter activity independent of DNA methylation
err2019-02-01
err44
errOAAI
errHartl, Dominik; Krebs, Arnaud R.; Grand, Ralph S.; Baubect, Tuncay; Isbel, Luke; Wirbelauer, Christiane; Burger, Lukas; Schuebeler, Dirk
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Wiz binds active promoters and CTCF-binding sites and is required for normal behaviour in the mouse
err2016-07-13
err18
errOAAI
errIsbel, Luke; Prokopuk, Lexie; Wu, Haoyu; Daxinger, Lucia; Oey, Harald; Spurling, Alex; Lawther, Adam J.; Hale, Matthew W.; Whitelaw, Emma
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Hypomethylation of ERVs in the sperm of mice haploinsufficient for the histone methyltransferase Setdb1 correlates with a paternal effect on phenotype
err2016-04-26
err23
errOAAI
errDaxinger, Lucia; Oey, Harald; Isbel, Luke; Whitelaw, Nadia C.; Youngson, Neil A.; Spurling, Alex; Vonk, Kelly K. D.; Whitelaw, Emma
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Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host Genome
err2015-12-01
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errOAAI
errIsbel, Luke; Srivastava, Rahul; Oey, Harald; Spurling, Alex; Daxinger, Lucia; Puthalakath, Hamsa; Whitelaw, Emma
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An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse
err2013-09-11
err67
errOAAI
errDaxinger, Lucia; Harten, Sarah K.; Oey, Harald; Epp, Trevor; Isbel, Luke; Huang, Edward; Whitelaw, Nadia; Apedaile, Anwyn; Sorolla, Anabel; Yong, Joan; Bharti, Vandhana; Sutton, Joanne; Ashe, Alyson; Pang, Zhenyi; Wallace, Nathan; Gerhardt, Daniel J.; Blewitt, Marnie E.; Jeddeloh, Jeffrey A.; Whitelaw, Emma
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