Not logged inSoybean oil-based HFD induces gut dysbiosis that leads to steatosis, hepatic inflammation and insulin resistance in mice
Jacob, Texy; Sindhu, Sardar; Hasan, Amal; Malik, Md. Zubbair; Arefanian, Hossein; Al-Rashed, Fatema; Nizam, Rasheeba; Kochumon, Shihab; Thomas, Reeby; Bahman, Fatemah; Shenouda, Steve; Wilson, Ajit; Akther, Nadeem; Al-Roub, Areej; Abukhalaf, Nermeen; Albeloushi, Shaima; Abu-Farha, Mohamed; Al Madhoun, Ashraf; Alzaid, Fawaz; Thanaraj, Thangavel Alphonse; Koistinen, Heikki A.; Tuomilehto, Jaakko; Al-Mulla, Fahd; Ahmad, Rasheed .png)
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SaveGut Dysbiosis Shaped by Cocoa Butter-Based Sucrose-Free HFD Leads to Steatohepatitis, and Insulin Resistance in MiceKochumon, Shihab; Malik, Md. Zubbair; Sindhu, Sardar; Arefanian, Hossein; Jacob, Texy; Bahman, Fatemah; Nizam, Rasheeba; Hasan, Amal; Thomas, Reeby; Al-Rashed, Fatema; Shenouda, Steve; Wilson, Ajit; Albeloushi, Shaima; Almansour, Nourah; Alhamar, Ghadeer; Al Madhoun, Ashraf; Alzaid, Fawaz; Thanaraj, Thangavel Alphonse; Koistinen, Heikki A.; Tuomilehto, Jaakko; Al-Mulla, Fahd; Ahmad, Rasheed Share Save Share Save Sunflower Oil HFD Feeding in Mice Leads to Gut Dysbiosis, Mild Steatohepatitis, and Impaired Glycemic ControlSindhu, Sardar T. A. K.; Bahman, Fatemah; Malik, Mohammad Zubbair; Arefanian, Hossein; Alrashed, Fatema; Nizam, Rasheeba; Kochumon, Shihab P.; Thomas, Reeby S.; Albeloushi, Shaima; Hasan, Amal; Abu-Farha, Mohamed; Al Madhoun, Ashraf; Thangavel, Alphonse T.; Almulla, Fahd; Ahmad, Rasheed Share Save Sustained TNF-a Transcription Triggered in Obesity through H3K9/K18 Acetylation Is Associated with Metabolic ImpairmentsAhmad, Rasheed; Bahman, Fatemah; Kochumon, Shihab P.; Jacob, Texy K.; Alrashed, Fatema; Wilson, Ajit; Arefanian, Hossein; Thomas, Reeby S.; Akhter, Nadeem; Al-Mansour, Nourah; Albeloushi, Shaima; Al Madhoun, Ashraf; Sindhu, Sardar T. A. K.; Alzaid, Fawaz; Almulla, Fahd Share Save Neutral Sphingomyelinase 2 Inhibition Limits Hepatic Steatosis and InflammationAl-Rashed, Fatema; Arefanian, Hossein; Al Madhoun, Ashraf; Bahman, Fatemah; Sindhu, Sardar; Alsaeed, Halemah; Jacob, Texy; Thomas, Reeby; Al-Roub, Areej; Alzaid, Fawaz; Malik, M. D. Zubbair; Nizam, Rasheeba; Thanaraj, Thangavel Alphonse; Al-Mulla, Fahd; Hannun, Yusuf A.; Ahmad, Rasheed Share Save ER Stress Drives the VEGF Expression in Monocytic Cells by Mechanisms Involving CHOP/ROS/HIF-1alpha/NRF2 and NF-kappaB/p38 MAPK PathwaysSindhu, Sardar A. K.; Akhter, Nadeem; Wilson, Ajit; Arefanian, Hossein; Al Madhoun, Ashraf; Thomas, Reeby S.; Kochumon, Shihab P.; Alrashed, Fatema; Bahman, Fatemah; Alzaid, Fawaz; Almulla, Fahd; Ahmad, Rasheed Share Save Differential Effects of Cocoa Butter, Sunflower, Soybean, and Fish Oil Based Sucrose-Free HFDs on Hepatic Steatosis, Lipogenesis, Inflammation, and Insulin Resistance in MiceAhmad, Rasheed; Jacob, Texy K.; Kochumon, Shihab P.; Thomas, Reeby S.; Shenouda, Steve; Akhter, Nadeem; Wilson, Ajit; Bahman, Fatemah; Hasan, Amal; Alrashed, Fatema; Arefanian, Hossein; Al Madhoun, Ashraf; Almulla, Fahd; Sindhu, Sardar T. A. K. Share Save Share Save Adipose Tissue Caveolin-1 Upregulation in Obesity Involves TNF-a/NF-?B Mediated SignalingAl Madhoun, Ashraf; Kochumon, Shihab; Haddad, Dania; Thomas, Reeby; Nizam, Rasheeba; Miranda, Lavina; Sindhu, Sardar; Bitar, Milad S.; Ahmad, Rasheed; Al-Mulla, Fahd Share Save Expression of Steroid Receptor RNA Activator 1 (SRA1) in the Adipose Tissue Is Associated with TLRs and IRFs in DiabesityKochumon, Shihab; Arefanian, Hossein; Sindhu, Sardar; Thomas, Reeby; Jacob, Texy; Al-Sayyar, Amnah; Shenouda, Steve; Al-Rashed, Fatema; Koistinen, Heikki A.; Al-Mulla, Fahd; Tuomilehto, Jaakko; Ahmad, Rasheed Share Save Caveolin-1 rs1997623 Single Nucleotide Polymorphism Creates a New Binding Site for the Early B-Cell Factor 1 That Instigates Adipose Tissue CAV1 Protein OverexpressionAl Madhoun, Ashraf; Haddad, Dania; Nizam, Rasheeba; Miranda, Lavina; Kochumon, Shihab; Thomas, Reeby; Thanaraj, Thangavel Alphonse; Ahmad, Rasheed; Bitar, Milad S.; Al-Mulla, Fahd Share Save Increased Adipose Tissue Expression of IL-23 Associates with Inflammatory Markers in People with High LDL CholesterolKochumon, Shihab; Hasan, Amal; Al-Rashed, Fatema; Sindhu, Sardar; Thomas, Reeby; Jacob, Texy; Al-Sayyar, Amnah; Arefanian, Hossein; Al Madhoun, Ashraf; Al-Ozairi, Ebaa; Alzaid, Fawaz; Koistinen, Heikki A.; Al-Mulla, Fahd; Tuomilehto, Jaakko; Ahmad, Rasheed Share Save Share Save Hepatic IRF3 fuels dysglycemia in obesity through direct regulation of Ppp2r1bPatel, Suraj J.; Liu, Nan; Piaker, Sam; Gulko, Anton; Andrade, Maynara L.; Heyward, Frankie D.; Sermersheim, Tyler; Edinger, Nufar; Srinivasan, Harini; Emont, Margo P.; Westcott, Gregory P.; Luther, Jay; Chung, Raymond T.; Yan, Shuai; Kumari, Manju; Thomas, Reeby; Deleye, Yann; Tchernof, Andre; White, Phillip J.; Baselli, Guido A.; Meroni, Marica; De Jesus, Dario F.; Ahmad, Rasheed; Kulkarni, Rohit N.; Valenti, Luca; Tsai, Linus; Rosen, Evan D. Share Save IL-1β and TNFα Cooperativity in Regulating IL-6 Expression in Adipocytes Depends on CREB Binding and H3K14 AcetylationAl-Roub, Areej; Al Madhoun, Ashraf; Akhter, Nadeem; Thomas, Reeby; Miranda, Lavina; Jacob, Texy; Al-Ozairi, Ebaa; Al-Mulla, Fahd; Sindhu, Sardar; Ahmad, Rasheed Share Save Adipose Tissue Steroid Receptor RNA Activator 1 (SRA1) Expression Is Associated with Obesity, Insulin Resistance, and InflammationKochumon, Shihab; Arefanian, Hossein; Sindhu, Sardar; Shenouda, Steve; Thomas, Reeby; Al-Mulla, Fahd; Tuomilehto, Jaakko; Ahmad, Rasheed Share Save Ceramide kinase regulates TNF-α-induced immune responses in human monocytic cellsAl-Rashed, Fatema; Ahmad, Zunair; Snider, Ashley J.; Thomas, Reeby; Kochumon, Shihab; Melhem, Motasem; Sindhu, Sardar; Obeid, Lina M.; Al-Mulla, Fahd; Hannun, Yusuf A.; Ahmad, Rasheed Share Save Share Save Share Save 
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