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B cell-derived acetylcholine promotes liver regeneration by regulating Kupffer cell and hepatic CD8+T cell function Modares, Nastaran Fazel; Hendrikse, Liam D.; Smith, Logan K.; Paul, Michael St.; Haight, Jillian; Luo, Ping; Liu, Shaofeng; Fortin, Jerome; Tong, Frances K.; Wakeham, Andrew C.; Jafari, Soode Moghadas; Zheng, Chunxing; Buckland, Mackenzie; Flick, Robert; Silvester, Jennifer; Berger, Thorsten; Ketela, Troy; Helke, Simone; Foffi, Erica; Niavarani, Raheleh; Saunders, Mary E.; Colonna, Isabelle; David, Bruna Araujo; Rastogi, Tashi; Lee, Woo; Kubes, Paul; Saunders, Mary; Mak, Tak W. Share Save
Single-Cell Proteogenomic Analysis of Clonal Evolution in Patient-Derived Xenograft Models of AML Treated with IDH Inhibitors Liu, Alex; Cathelin, Severine; Yang, Yitong; Aboualizadeh, Farzaneh; Abow, Amina; Basi, Gurbaksh; Li, Lance; Dai, David L.; Maher, Abdula; Grignano, Eric; Hosseini, Mohsen; Ayyathan, Dhanoop Manikoth; Wang, Vivian; Ketela, Troy; Marchione, Dylan; Tron, Adriana; Arruda, Andrea; Minden, Mark D.; Chan, Steven M. Share Save
Multiome Single Cell Analyses Identify a Distinct CD8+T Cell Phenotype Linked to Treatment Response in PTLD Aoki, Tomohiro; Zhao, Davidson; Lang, Noemie; Yin, Yifan; Liu, Ting; Hong, Michael; Regala, Johanna; Ketela, Troy; Prica, Anca; Kuruvilla, John; Farinha, Pedro; Delabie, Jan; Gaiti, Federico; Savage, Kerry J.; Scott, David W.; Kridel, Robert Share Save
Leptin-Enhanced JAK-STAT Signaling in Acute Myeloid Leukemia-Derived Mesenchymal Stromal Cells and Its Implications for Disease Progression Bhatti, Muzaffar; Travas, Anthea; Ayansola, Oyeronke; Ambalavanan, Amirthagowri; Kim, Jaeyoon John; Pyne, Danielle; Ketela, Troy; Arruda, Andrea; Minden, Mark D.; Keating, Armand; Kim, Dennis Dong Hwan Share Save
Obesity and the cerebral cortex: Underlying neurobiology in mice and humans Patel, Yash; Woo, Anita; Shi, Sammy; Ayoub, Ramy; Shin, Jean; Botta, Amy; Ketela, Troy; Sung, Hoon-Ki; Lerch, Jason; Nieman, Brian; Paus, Tomas; Pausova, Zdenka Share Save
Decreased left heart flow in fetal lambs causes left heart hypoplasia and pro-fibrotic tissue remodeling Reuter, Miriam S.; Sokolowski, Dustin J.; Diaz-Mejia, J. Javier; Keunen, Johannes; de Vrijer, Barbra; Chan, Cadia; Wang, Liangxi; Ryan, Greg; Chiasson, David A.; Ketela, Troy; Scherer, Stephen W.; Wilson, Michael D.; Jaeggi, Edgar; Chaturvedi, Rajiv R. Share Save
Identification of acquired Notch3 dependency in metastatic Head and Neck Cancer Kondratyev, Maria; Pesic, Aleksandra; Ketela, Troy; Stickle, Natalie; Beswick, Christine; Shalev, Zvi; Marastoni, Stefano; Samadian, Soroush; Dvorkin-Gheva, Anna; Sayad, Azin; Bashkurov, Mikhail; Boasquevisque, Pedro; Datti, Alessandro; Pugh, Trevor J.; Virtanen, Carl; Moffat, Jason; Grenman, Reidar A.; Koritzinsky, Marianne; Wouters, Bradly G. Share Save
Genome-wide in vivo screen of circulating tumor cells identifies SLIT2 as a regulator of metastasis Xia, Fan; Ma, Yuan; Chen, Kangfu; Duong, Bill; Ahmed, Sharif; Atwal, Randy; Philpott, David; Ketela, Troy; Pantea, Jennifer; Lin, Sichun; Angers, Stephane; Kelley, Shana O. Share Save
Irx3 and Irx5 in Ins2-Cre+ cells regulate hypothalamic postnatal neurogenesis and leptin response Son, Joe Eun; Dou, Zhengchao; Kim, Kyoung-Han; Wanggou, Siyi; Bin Cha, Vincent Su; Mo, Rong; Zhang, Xiaoyun; Chen, Xinyu; Ketela, Troy; Li, Xuejun; Huang, Xi; Hui, Chi-chung Share Save
A genome-wide CRISPR/Cas9 screen in acute myeloid leukemia cells identifies regulators of TAK-243 sensitivity Barghout, Samir H.; Aman, Ahmed; Nouri, Kazem; Blatman, Zachary; Arevalo, Karen; Thomas, Geethu E.; MacLean, Neil; Hurren, Rose; Ketela, Troy; Saini, Mehakpreet; Abohawya, Moustafa; Kiyota, Taira; Al-Awar, Rima; Schimmer, Aaron D. Share Save
Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity Richards, Laura M.; Whitley, Owen K. N.; MacLeod, Graham; Cavalli, Florence M. G.; Coutinho, Fiona J.; Jaramillo, Julia E.; Svergun, Nataliia; Riverin, Mazdak; Croucher, Danielle C.; Kushida, Michelle; Yu, Kenny; Guilhamon, Paul; Rastegar, Naghmeh; Ahmadi, Moloud; Bhatti, Jasmine K.; Bozek, Danielle A.; Li, Naijin; Lee, Lilian; Che, Clare; Luis, Erika; Park, Nicole I.; Xu, Zhiyu; Ketela, Troy; Moore, Richard A.; Marra, Marco A.; Spears, Julian; Cusimano, Michael D.; Das, Sunit; Bernstein, Mark; Haibe-Kains, Benjamin; Lupien, Mathieu; Luchman, H. Artee; Weiss, Samuel; Angers, Stephane; Dirks, Peter B.; Bader, Gary D.; Pugh, Trevor J. Share Save
Functional genomics identifies new synergistic therapies for retinoblastoma Aubry, Arthur; Pearson, Joel D.; Huang, Katherine; Livne-Bar, Izhar; Ahmad, Mohammad; Jagadeesan, Madhavan; Khetan, Vikas; Ketela, Troy; Brown, Kevin R.; Yu, Tao; Lu, Suying; Wrana, Jeffrey L.; Moffat, Jason; Bremner, Rod Share Save
Forward genetic screen in human podocytes identifies diphthamide biosynthesis genes as regulators of adhesion Cina, Davide P.; Ketela, Troy; Brown, Kevin R.; Chandrashekhar, Megha; Mero, Patricia; Li, Chengjin; Onay, Tuncer; Fu, Yulong; Han, Zhe; Saleem, Moin; Moffat, Jason; Quaggin, Susan E. Share Save
Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response Sharon, David; Cathelin, Severine; Mirali, Sara; Di Trani, Justin M.; Yanofsky, David J.; Keon, Kristine A.; Rubinstein, John L.; Schimmer, Aaron D.; Ketela, Troy; Chan, Steven M. Share Save
Cell surface targets in head and neck cancer Kondratyev, Maria; Pesic, Aleksandra; Sayad, Azin; Ketela, Troy; Stickle, Natalie; Virtanen, Carl; Moffat, Jason; Ailles, Laurie; Koritzinsky, Marianne; Wouters, Brad Share Save
The Mitochondrial Transacylase, Tafazzin, Regulates AML Stemness by Modulating Intracellular Levels of Phospholipids (vol 24, pg 621, 2019) Seneviratne, Ayesh K.; Xu, Mingjing; Henao, Juan J. Aristizabal; Fajardo, Val A.; Hao, Zhenyue; Voisin, Veronique; Xu, G. Wei; Hurren, Rose; Kim, S.; MacLean, Neil; Wang, Xiaoming; Gronda, Marcela; Jeyaraju, Danny; Jitkova, Yulia; Ketela, Troy; Mullokandov, Michael; Sharon, David; Thomas, Geethu; Chouinard-Watkins, Raphael; Hawley, James R.; Schafer, Caitlin; Yau, Helen Loo; Khuchua, Zaza; Aman, Ahmed; Al-awar, Rima; Gross, Atan; Claypool, Steven M.; Bazinet, Richard P.; Lupien, Mathieu; Chan, Steven; De Carvalho, Daniel D.; Minden, Mark D.; Bader, Gary D.; Stark, Ken D.; LeBlanc, Paul; Schimmer, Aaron D. Share Save
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Preclinical efficacy and sensitivity determinants of evofosfamide in molecularly defined models of head and neck squamous cell carcinoma Hunter, Francis W.; Shome, Avik; Li, Dan; Wong, Way W.; Tsai, Peter; Poonawala, Nooriyah; Kakadiya, Purvi M.; Ketela, Troy M.; Kondratyev, Maria K.; Lynch, Courtney R.; Lee, Tet-Woo; Tran, Khanh B.; Devaux, Jules B.; Zussman, Rachel; Hong, Cho R.; Kee, Dennis; Macann, Andrew M.; Hickey, Anthony J.; Bohlander, Stefan K.; Print, Cristin G.; Wilson, William R.; Wouters, Bradly G.; Jamieson, Stephen M. Share Save
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