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Improving detection of carcinoma in situ in bladder cancer: urinary cytology vs the Xpert® BC Monitor Haas, Maximilian; Kriegmair, Maximilian C.; Breyer, Johannes; Sikic, Danijel; Wezel, Felix; Roghmann, Florian; Brehmer, Mirco; Wirtz, Ralph M.; Jarczyk, Jonas; Erben, Philipp; Bahlinger, Veronika; Goldschmidt, Franziska; Fechner, Guido; Chen, Jack; Paxinos, Ellen; Bates, Michael; Zengerling, Friedemann; Bolenz, Christian; Burger, Maximilian; Hartmann, Arndt; Eckstein, Markus Share Save
Molecular Urothelial Tumor Cell Subtypes Remain Stable During Metastatic Evolution Cox, Alexander; Kluemper, Niklas; Stein, Johannes; Sikic, Danijel; Breyer, Johannes; Bolenz, Christian; Roghmann, Florian; Erben, Philipp; Wirtz, Ralph M.; Wullich, Bernd; Ritter, Manuel; Hoelzel, Michael; Schwamborn, Kristina; Horn, Thomas; Gschwend, Juergen; Hartmann, Arndt; Weichert, Wilko; Erlmeier, Franziska; Eckstein, Markus Share Save
A deep-learning workflow to predict upper tract urothelial carcinoma protein-based subtypes from H&E slides supporting the prioritization of patients for molecular testing Angeloni, Miriam; van Doeveren, Thomas; Lindner, Sebastian; Volland, Patrick; Schmelmer, Jorina; Foersch, Sebastian; Matek, Christian; Stoehr, Robert; Geppert, Carol, I; Heers, Hendrik; Wach, Sven; Taubert, Helge; Sikic, Danijel; Wullich, Bernd; van Leenders, Geert J. L. H.; Zaburdaev, Vasily; Eckstein, Markus; Hartmann, Arndt; Boormans, Joost L.; Ferrazzi, Fulvia; Bahlinger, Veronika Share Save
Proposal for a Novel Histological Scoring System as a Potential Grading Approach for Muscle-invasive Urothelial Bladder Cancer Correlating with Disease Aggressiveness and Patient Outcomes Eckstein, Markus; Matek, Christian; Wagner, Paul; Erber, Ramona; Buettner-Herold, Maike; Wild, Peter J.; Taubert, Helge; Wach, Sven; Sikic, Danijel; Wullich, Bernd; Geppert, Carol I.; Comperat, Eva M.; Lopez-Beltran, Antonio; Montironi, Rodolfo; Cheng, Liang; van der Kwast, Theodorus; Colecchia, Maurizio; van Rhijn, Bas W. G.; Amin, Mahul B.; Netto, George J.; Lehmann, Jan; Stoeckle, Michael; Junker, Kerstin; Hartmann, Arndt; Bertz, Simone Share Save
Associations of TACSTD2/TROP2 and NECTIN-4/NECTIN-4 with molecular subtypes, PD-L1 expression, and FGFR3 mutational status in two advanced urothelial bladder cancer cohorts Bahlinger, Veronika; Branz, Annalena; Strissel, Pamela L.; Strick, Reiner; Lange, Fabienne; Geppert, Carol, I; Kluemper, Niklas; Hoelzel, Michael; Wach, Sven; Taubert, Helge; Sikic, Danijel; Wullich, Bernd; Angeloni, Miriam; Ferrazzi, Fulvia; Diehl, Lauri; Kovalenko, Maria; Elboudwarej, Emon; Juergensmeier, Juliane M.; Hartmann, Arndt; Eckstein, Markus Share Save
Proposal for a Novel Histological Scoring System as a Potential Grading Approach for Muscle-invasive Urothelial Bladder Cancer Correlating with Disease Aggressiveness and Patient Outcomes (Aug, 10.1016/j.euo.2023.07.011, 2023) Eckstein, Markus; Matek, Christian; Wagner, Paul; Erber, Ramona; Buettner-Herold, Maike; Wild, Peter J.; Taubert, Helge; Wach, Sven; Sikic, Danijel; Wullich, Bernd; Geppert, Carol I.; Comperat, Eva M.; Lopez-Beltran, Antonio; Montironi, Rodolfo; Cheng, Liang; van der Kwast, Theodorus; Colecchia, Maurizio; van Rhijn, Bas W. G.; Amin, Mahul B.; Netto, George J.; Lehmann, Jan; Stoeckle, Michael; Junker, Kerstin; Hartmann, Arndt; Bertz, Simone Share Save
PD-L1 (CD274) promoter hypomethylation predicts immunotherapy response in metastatic urothelial carcinoma Kluemper, Niklas; Wuest, Lennert; Saal, Jonas; Ralser, Damian J.; Zarbl, Romina; Jarczyk, Jonas; Breyer, Johannes; Sikic, Danijel; Wullich, Bernd; Bolenz, Christian; Roghmann, Florian; Hoelzel, Michael; Ritter, Manuel; Strieth, Sebastian; Hartmann, Arndt; Erben, Philipp; Wirtz, Ralph M.; Landsberg, Jennifer; Dietrich, Dimo; Eckstein, Markus Share Save
Xpert bladder cancer monitor to predict the need for a second TURB (MoniTURB trial) Breyer, Johannes; Eckstein, Markus; Sikic, Danijel; Wezel, Felix; Roghmann, Florian; Brehmer, Mirco; Wirtz, Ralph M.; Jarczyk, Jonas; Erben, Philipp; Bahlinger, Veronika; Goldschmidt, Franziska; Fechner, Guido; Chen, Jack; Paxinos, Ellen; Bates, Michael; Haas, Maximilian; Zengerling, Friedemann; Bolenz, Christian; Burger, Maximilian; Hartmann, Arndt; Kriegmair, Maximilian C. Share Save
Comprehensive genomic characterization of early-stage bladder cancer from 438 patients by whole genome- and exome sequencing Prip, Frederik; Lamy, Philippe; Nordentoft, Iver; Lindskrog, Sia Viborg; Strandgaard, Trine; Birkenkamp-Demtroder, Karin; Hermann, Gregers G.; Petersen, Astrid C.; Bahlinger, Veronika; Grimm, Marc-Oliver; Horstmann, Marcus; Mogensen, Karin; Nawroth, Roman; Segersten, Ulrika; Sikic, Danijel; van Kessel, Kim E. M.; Maurer, Tobias; Simic, Tatjana; Hartmann, Arndt; Zwarthoff, Ellen C. C.; Malmstrom, Per-Uno; Steiniche, Torben; Jensen, Jorgen Bjerggaard; Malats, Nuria; Real, Francisco X.; Dyrskjot, Lars Share Save
Spatial Immunephenotypes of Distant Metastases but not Matched Primary Urothelial Carcinomas Predict Response to Immune Checkpoint Inhibition Erlmeier, Franziska; Klumper, Niklas; Landgraf, Laura; Strissel, Pamela L.; Strick, Reiner; Sikic, Danijel; Taubert, Helge; Wach, Sven; Geppert, Carol I.; Bahlinger, Veronika; Breyer, Johannes; Ritter, Manuel; Bolenz, Christian; Roghmann, Florian; Erben, Philipp; Schwamborn, Kristina; Wirtz, Ralph M.; Horn, Thomas; Wullich, Bernd; Hoelzelg, Michael; Hartmann, Arndt; Gschwend, Jurgen E.; Weichertd, Wilko; Eckstein, Markus Share Save
C-reactive protein flare predicts response to anti-PD-(L)1 immune checkpoint blockade in metastatic urothelial carcinoma Kluemper, Niklas; Sikic, Danijel; Saal, Jonas; Buettner, Thomas; Goldschmidt, Franziska; Jarczyk, Jonas; Becker, Philippe; Zeuschner, Philip; Weinke, Maximilian; Kalogirou, Charis; Breyer, Johannes; Burger, Maximilian; Nuhn, Philipp; Tully, Karl; Roghmann, Florian; Bolenz, Christian; Zengerling, Friedemann; Wirtz, Ralph M.; Muders, Michael; Kristiansen, Glen; Bald, Tobias; Ellinger, Joerg; Wullich, Bernd; Hoelzel, Michael; Hartmann, Arndt; Erben, Philipp; Ritter, Manuel; Eckstein, Markus Share Save
CTLA4 promoter hypomethylation is a negative prognostic biomarker at initial diagnosis but predicts response and favorable outcome to anti-PD-1 based immunotherapy in clear cell renal cell carcinoma Kluemper, Niklas; Ralser, Damian J.; Zarbl, Romina; Schlack, Katrin; Schrader, Andres Jan; Rehlinghaus, Marc; Hoffmann, Michele J.; Niegisch, Guenter; Uhlig, Annemarie; Trojan, Lutz; Steinestel, Julie; Steinestel, Konrad; Wirtz, Ralph M.; Sikic, Danijel; Eckstein, Markus; Kristiansen, Glen; Toma, Marieta; Hoelzel, Michael; Ritter, Manuel; Strieth, Sebastian; Ellinger, Joerg; Dietrich, Dimo Share Save
Combination of GP88 Expression in Tumor Cells and Tumor-Infiltrating Immune Cells Is an Independent Prognostic Factor for Bladder Cancer Patients Eckstein, Markus; Lieb, Verena; Jung, Rudolf; Sikic, Danijel; Weigelt, Katrin; Stohr, Robert; Geppert, Carol; Weyerer, Veronika; Bertz, Simone; Serrero, Ginette; Yue, Binbin; Hartmann, Arndt; Wullich, Bernd; Taubert, Helge; Wach, Sven Share Save
High Androgen Receptor mRNA Expression Is Associated with Improved Outcome in Patients with High-Risk Non-Muscle-Invasive Bladder Cancer Sikic, Danijel; Taubert, Helge; Wirtz, Ralph M.; Breyer, Johannes; Eckstein, Markus; Weyerer, Veronika; Kubon, Jennifer; Erben, Philipp; Bolenz, Christian; Burger, Maximilian; Hartmann, Arndt; Wullich, Bernd; Wach, Sven; Keck, Bastian Share Save
An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer Lindskrog, Sia Viborg; Prip, Frederik; Lamy, Philippe; Taber, Ann; Groeneveld, Clarice S.; Birkenkamp-Demtroder, Karin; Jensen, Jorgen Bjerggaard; Strandgaard, Trine; Nordentoft, Iver; Christensen, Emil; Sokac, Mateo; Birkbak, Nicolai J.; Maretty, Lasse; Hermann, Gregers G.; Petersen, Astrid C.; Weyerer, Veronika; Grimm, Marc-Oliver; Horstmann, Marcus; Sjodahl, Gottfrid; Hoglund, Mattias; Steiniche, Torben; Mogensen, Karin; de Reynies, Aurelien; Nawroth, Roman; Jordan, Brian; Lin, Xiaoqi; Dragicevic, Dejan; Ward, Douglas G.; Goel, Anshita; Hurst, Carolyn D.; Raman, Jay D.; Warrick, Joshua, I; Segersten, Ulrika; Sikic, Danijel; van Kessel, Kim E. M.; Maurer, Tobias; Meeks, Joshua J.; DeGraff, David J.; Bryan, Richard T.; Knowles, Margaret A.; Simic, Tatjana; Hartmann, Arndt; Zwarthoff, Ellen C.; Malmstrom, Per-Uno; Malats, Nuria; Real, Francisco X.; Dyrskjot, Lars Share Save
Bladder Tumor Subtype Commitment Occurs in Carcinoma In Situ Driven by Key Signaling Pathways Including ECM Remodeling Wullweber, Adrian; Strick, Reiner; Lange, Fabienne; Sikic, Danijel; Taubert, Helge; Wach, Sven; Wullich, Bernd; Bertz, Simone; Weyerer, Veronika; Stoehr, Robert; Breyer, Johannes; Burger, Maximilian; Hartmann, Arndt; Strissel, Pamela L.; Eckstein, Markus Share Save
Immune Cell-Associated Protein Expression Helps to Predict Survival in Muscle-Invasive Urothelial Bladder Cancer Patients after Radical Cystectomy and Optional Adjuvant Chemotherapy Taubert, Helge; Eckstein, Markus; Epple, Elena; Jung, Rudolf; Weigelt, Katrin; Lieb, Verena; Sikic, Danijel; Stoehr, Robert; Geppert, Carol; Weyerer, Veronika; Bertz, Simone; Kehlen, Astrid; Hartmann, Arndt; Wullich, Bernd; Wach, Sven Share Save
FOXA1 Gene Expression for Defining Molecular Subtypes of Muscle-Invasive Bladder Cancer after Radical Cystectomy Sikic, Danijel; Eckstein, Markus; Wirtz, Ralph M.; Jarczyk, Jonas; Worst, Thomas S.; Porubsky, Stefan; Keck, Bastian; Kunath, Frank; Weyerer, Veronika; Breyer, Johannes; Otto, Wolfgang; Rinaldetti, Sebastien; Bolenz, Christian; Hartmann, Arndt; Wullich, Bernd; Erben, Philipp Share Save
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