Robert A. Grassucci - Publications, H-index & Citations

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Robert A. Grassucci

Howard Hughes Medical Institute

58H-index

146Paper Count

1.2WCitation Count

Published Papers 36

Publication Date

Symmetric activation and modulation of the human calcium-sensing receptor

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-12-16

OAAI

Park, Jinseo; Zuo, Hao; Frangaj, Aurel; Fu, Ziao; Yen, Laura Y.; Zhang, Zhening; Mosyak, Lidia; Slavkovich, Vesna N.; Liu, Jonathan; Ray, Kimberly M.; Cao, Baohua; Vallese, Francesca; Geng, Yong; Chen, Shaoxia; Grassucci, Robert; Dandey, Venkata P.; Tan, Yong Zi; Eng, Edward; Lee, Yeji; Kloss, Brian; Liu, Zheng; Hendrickson, Wayne A.; Potter, Clinton S.; Carragher, Bridget; Graziano, Joseph; Conigrave, Arthur D.; Frank, Joachim; Clarke, Oliver B.; Fan, Qing R.

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Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2020-06-01

OAAI

Zheng, Xiangdong; Fu, Ziao; Su, Deyuan; Zhang, Yuebin; Li, Minghui; Pan, Yaping; Li, Huan; Li, Shufang; Grassucci, Robert A.; Ren, Zhenning; Hu, Zhengshan; Li, Xueming; Zhou, Ming; Li, Guohui; Frank, Joachim; Yang, Jian

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Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells

SCIENCE ADVANCES

IF12.5

2020-04-03

OAAI

Carter, Stephen D.; Hampton, Cheri M.; Langlois, Robert; Melero, Roberto; Farino, Zachary J.; Calderon, Michael J.; Li, Wen; Wallace, Callen T.; Ngoc Han Tran; Grassucci, Robert A.; Siegmund, Stephanie E.; Pemberton, Joshua; Morgenstern, Travis J.; Eisenman, Leanna; Aguilar, Jenny, I; Greenberg, Nili L.; Levy, Elana S.; Yi, Edward; Mitchell, William G.; Rice, William J.; Wigge, Christoph; Pilli, Jyotsna; George, Emily W.; Aslanoglou, Despoina; Courel, Maite; Freyberg, Robin J.; Javitch, Jonathan A.; Wills, Zachary P.; Area-Gomez, Estela; Shiva, Sruti; Bartolini, Francesca; Volchuk, Allen; Murray, Sandra A.; Aridor, Meir; Fish, Kenneth N.; Walter, Peter; Balla, Tamas; Fass, Deborah; Wolf, Sharon G.; Watkins, Simon C.; Maria Carazo, Jose; Jensen, Grant J.; Frank, Joachim; Freyberg, Zachary

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The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy

NATURE COMMUNICATIONS

IF15.7

2019-06-12

OAAI

Fu, Ziao; Indrisiunaite, Gabriele; Kaledhonkar, Sandip; Shah, Binita; Sun, Ming; Chen, Bo; Grassucci, Robert A.; Ehrenberg, Mans; Frank, Joachim

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The Structural Basis for Release Factor Activation during Translation Termination Revealed by Time-Resolved Cryogenic Electron Microscopy

BIOPHYSICAL JOURNAL

IF3.1

2019-02-01

OAAI

Fu, Ziao; Indrisiunaite, Gabriele; Kaledhonkar, Sandip; Shah, Binita; Sun, Ming; Chen, Bo; Grassucci, Robert A.; Ehrenberg, Mans; Frank, Joachim

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Structure and activity of lipid bilayer within a membrane-protein transporter

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-12-03

109

OAAI

Qiu, Weihua; Fu, Ziao; Xu, Guoyan G.; Grassucci, Robert A.; Zhang, Yan; Frank, Joachim; Hendrickson, Wayne A.; Guo, Youzhong

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Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes

NEURON

IF15

2017-05-01

OAAI

Twomey, Edward C.; Yelshanskaya, Maria V.; Grassucci, Robert A.; Frank, Joachim; Sobolevsky, Alexander I.

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Functional Study of the Ryanodine Receptor Type 1 using Cryo-Electron Microscopy

BIOPHYSICAL JOURNAL

IF3.1

2017-02-01

OAAI

des Georges, Amedee; Clarke, Oliver B.; Zalk, Ran; Yuan, Qi; Condon, Kendall J.; Grassucci, Robert A.; Hendrickson, Wayne A.; Marks, Andrew R.; Frank, Joachim

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Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-10-10

OAAI

Liu, Zheng; Gutierrez-Vargas, Cristina; Wei, Jia; Grassucci, Robert A.; Ramesh, Madhumitha; Espina, Noel; Sun, Ming; Tutuncuoglu, Beril; Madison-Antenucci, Susan; Woolford, John L., Jr.; Tong, Liang; Frank, Joachim

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CTF Challenge: Result summary

JOURNAL OF STRUCTURAL BIOLOGY

IF5.1

2015-06-01

OAAI

Marabini, Roberto; Carragher, Bridget; Chen, Shaoxia; Chen, James; Cheng, Anchi; Downing, Kenneth H.; Frank, Joachim; Grassucci, Robert A.; Heymann, J. Bernard; Jiang, Wen; Jonic, Slavica; Liao, Hstau Y.; Ludtke, Steven J.; Patwari, Shail; Piotrowski, Angela L.; Quintana, Adrian; Sorzano, Carlos O. S.; Stahlberg, Henning; Vargas, Javier; Voss, Neil R.; Chiu, Wah; Carazo, Jose M.

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Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29

BIOPHYSICAL JOURNAL

IF3.1

2014-01-01

OAAI

Hashem, Yaser; Georges, Amedee des; Dhote, Vidya; Langlois, Robert; Liao, Hstau Y.; Grassucci, Robert A.; Hellen, Christopher U. T.; Pestova, Tatyana V.; Frank, Joachim

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Structure of the mammalian ribosomal pre-termination complex associated with eRF1•eRF3•GDPNP

NUCLEIC ACIDS RESEARCH

IF13.1

2013-12-11

OAAI

des Georges, Amedee; Hashem, Yaser; Unbehaun, Anett; Grassucci, Robert A.; Taylor, Derek; Hellen, Christopher U. T.; Pestova, Tatyana V.; Frank, Joachim

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Affinity grid-based cryo-EM of PKC binding to RACK1 on the ribosome

JOURNAL OF STRUCTURAL BIOLOGY

IF5.1

2013-02-01

OAAI

Sharma, Gyanesh; Pallesen, Jesper; Das, Sanchaita; Grassucci, Robert; Langlois, Robert; Hampton, Cheri M.; Kelly, Deborah F.; des Georges, Amedee; Frank, Joachim

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Cryo-EM structure of the mammalian eukaryotic release factor eRF1-eRF3-associated termination complex

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2012-10-04

OAAI

Taylor, Derek; Unbehaun, Anett; Li, Wen; Das, Sanchaita; Lei, Jianlin; Liao, Hstau Y.; Grassucci, Robert A.; Pestova, Tatyana V.; Frank, Joachim

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The group II intron ribonucleoprotein precursor is a large, loosely packed structure

NUCLEIC ACIDS RESEARCH

IF13.1

2010-12-03

OAAI

Huang, Tao; Shaikh, Tanvir R.; Gupta, Kushol; Contreras-Martin, Lydia M.; Grassucci, Robert A.; Van Duyne, Gregory D.; Frank, Joachim; Belfort, Marlene

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Determination of signal-to-noise ratios and spectral SNRs in cryo-EM low-dose imaging of molecules

JOURNAL OF STRUCTURAL BIOLOGY

IF5.1

2009-05-01

OAAI

Baxter, William T.; Grassucci, Robert A.; Gao, Haixiao; Frank, Joachim

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Time-dependent insulin oligomer reaction pathway prior to fibril formation: Cooling and seeding

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2009-04-30

OAAI

Sorci, Mirco; Grassucci, Robert A.; Hahn, Ingrid; Frank, Joachim; Belfort, Georges

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Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2009-01-27

230

OAAI

Villa, Elizabeth; Sengupta, Jayati; Trabuco, Leonardo G.; LeBarron, Jamie; Baxter, William T.; Shaikh, Tanvir R.; Grassucci, Robert A.; Nissen, Poul; Ehrenberg, Mans; Schulten, Klaus; Frank, Joachim

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Exploration of parameters in cryo-EM leading to an improved density map of the E-coli ribosome

JOURNAL OF STRUCTURAL BIOLOGY

IF5.1

2008-10-01

OAAI

LeBarron, Jamie; Grassucci, Robert A.; Shaikh, Tanvir R.; Baxter, William T.; Sengupta, Jayati; Frank, Joachim

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Visualization of macromolecular complexes using cryo-electron microscopy with FEI Tecnai transmission electron microscopes

NATURE PROTOCOLS

IF16

2008-02-07

OAAI

Grassucci, Robert A.; Taylor, Derek; Frank, Joachim

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Research Directions