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Allogeneic CAR-DNT cell therapy to overcome spatial heterogeneity in glioblastoma Mah, Laura; Louie, Taye; Espinosa, Jessica Lopez; Snelling, Shannon; Lui, Hongrui; Lun, Xueqing; Nawata, Michele; Verhey, Ted; Manoharan, Varsha Thoppey; Chan, Jennifer; Morrissy, Sorana; Lee, Jongbok; Zemp, Franz; Mahoney, Douglas Share Save
A prototype mRNA LNP neoantigen vaccine remodels the tumour microenvironment of a syngeneic model of glioblastoma Snelling, Shannon; Pyczek, Joanna; Lun, Xueqing; Manoharan, Varsha; Liu, Jun; Gold, Matthew; Ellestad, Kristofor; Olsen, Kirsten; Wu, Yu; Karpov, Yury; Menon, Haritha; Tan, Yilin; Krishnan, Rajesh; Mahoney, Douglas; Morrissy, A. Sorana; Martin-Orozco, Natalia; Chan, Jennifer A. Share Save
Investigating EGFRvIII mRNA LNP vaccine-induced re-programming of the GBM TME using the 10x Genomics Visium HD platform Manoharan, Varsha Thoppey; Snelling, Shannon; Gill, Gurveer; Nechanitzky, Robert; Lun, Xueqing; Ellestad, Kristofer; Pyczek, Joanna; Olsen, Kirsten; Wu, Yu; Karpov, Yury; Liu, Jun; Gold, Matthew; Menon, Haritha; Tan, Yilin; Krishnan, Rajesh; Mahoney, Douglas; Martin-Orozco, Natalia; Chan, Jennifer; Morrissy, Sorana Share Save
A bivalent COVID-19 mRNA vaccine elicited broad immune responses and protection against Omicron subvariants infection Liu, Jun; Wang, Li; Kurtesi, Alexandra; Budylowski, Patrick; Potts, Kyle G.; Menon, Haritha; Tan, Yilin; Samaan, Philip; Liu, Xinan; Wang, Yisen; Hu, Queenie; Samson, Reuben; Qi, Freda; Evseev, Danyel; John, Cini; Ellestad, Kristofor K.; Fan, Yue; Budiman, Frans; Tohan, Ellaine Riczly; Udayakumar, Suji; Yang, Jennifer; Marcusson, Eric G.; Gingras, Anne-Claude; Mahoney, Douglas J.; Ostrowski, Mario A.; Martin-Orozco, Natalia Share Save
Divergent sex-specific pannexin-1 mechanisms in microglia and T cells underlie neuropathic pain Fan, Churmy Y.; Mcallister, Brendan B.; Stokes-Heck, Sierra; Harding, Erika K.; de Vasconcelos, Aliny Pereira; Mah, Laura K.; Lima, Lucas, V; van den Hoogen, Nynke J.; Rosen, Sarah F.; Ham, Boram; Zhang, Zizhen; Liu, Hongrui; Zemp, Franz J.; Burkhard, Regula; Geuking, Markus B.; Mahoney, Douglas J.; Zamponi, Gerald W.; Mogil, Jeffrey S.; Ousman, Shalina S.; Trang, Tuan Share Save
VSV△M51 drives CD8+ T cell-mediated tumour regression through infection of both cancer and non-cancer cells Rajwani, Jahanara; Vishnevskiy, Daniil; Turk, Madison; Naumenko, Victor; Gafuik, Chris; Kim, Dae-Sun; Mah, Laura K.; Snelling, Shannon; Gonzales, Gerone A.; Xue, Jingna; Chanda, Ayan; Potts, Kyle G.; Todesco, Hayley M.; Lau, Keith C. K.; Hildebrand, Karys M.; Chan, Jennifer A.; Liao, Shan; Monument, Michael J.; Hyrcza, Martin; Bose, Pinaki; Jenne, Craig N.; Canton, Johnathan; Zemp, Franz J.; Mahoney, Douglas J. Share Save
UNSUPERVISED DECONVOLUTION OF SPATIOTEMPORAL HETEROGENEITY REVEALS HIGH-RESOLUTION INVASION STATES IN GLIOBLASTOMA Manoharan, Varsha Thoppey; Abdelkareem, Aly; Brown, Samuel; Gillmor, Aaron; Hall, Courtney; Seo, Heewon; Narta, Kiran; Grewal, Sean; Ha Dang, Ngoc; Ahn, Bo Young; Osz, Kata; Lun, Xueqing; Mahoney, Douglas; Senger, Donna; Chan, Jennifer; Morrissy, Sorana Share Save
AN EGFRVIII RNA-LNP VACCINE PROTOTYPE ACHIEVES TUMOUR CLEARANCE IN A GBM MOUSE MODEL Snelling, Shannon; Nechanitzky, Robert; Lun, Xueqing; Ellestad, Kristofer; Pyczek, Joanna; Olsen, Kirsten; Wu, Yu; Karpov, Yury; Liu, Jun; Gold, Matthew; Menon, Haritha; Tan, Yilin; Krishnan, Rajesh; Mahoney, Douglas; Martin-Orozco, Natalia; Chan, Jennifer A. Share Save
The pore-forming apolipoprotein APOL7C drives phagosomal rupture and antigen cross-presentation by dendritic cells Gonzales, Gerone A.; Huang, Song; Wilkinson, Liam; Nguyen, Jenny A.; Sikdar, Saif; Piot, Cecile; Naumenko, Victor; Rajwani, Jahanara; Wood, Cassandra M.; Dinh, Irene; Moore, Melanie; Cedeno, Eymi; McKenna, Neil; Polyak, Maria J.; Amidian, Sara; Ebacher, Vincent; Rosin, Nicole L.; Carneiro, Matheus B.; Surewaard, Bas; Peters, Nathan C.; Mody, Christopher H.; Biernaskie, Jeff; Yates, Robin M.; Mahoney, Douglas J.; Canton, Johnathan Share Save
Spatiotemporal modeling reveals high-resolution invasion states in glioblastoma Manoharan, Varsha Thoppey; Abdelkareem, Aly; Gill, Gurveer; Brown, Samuel; Gillmor, Aaron; Hall, Courtney; Seo, Heewon; Narta, Kiran; Grewal, Sean; Dang, Ngoc Ha; Ahn, Bo Young; Osz, Kata; Lun, Xueqing; Mah, Laura; Zemp, Franz; Mahoney, Douglas; Senger, Donna L.; Chan, Jennifer A.; Morrissy, A. Sorana Share Save
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Next-generation mRNA-LNP vaccine prototype achieves tumor clearance in a GBM mouse model Nechanitzky, Robert; Snelling, Shannon Snelling; Ellestad, Kristofor; Lun, Xueqing; Olsen, Kirstin; Wu, Yu; Karpov, Yury; Liu, Jun; Gold, Matthew; Menon, Haritha; Krishnan, Rajesh; Georgantas, Robert; Ohashi, Pamela S.; Mahoney, Douglas J.; Chan, Jennifer A.; Martin-Orozco, Natalia Share Save
ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97 Pozner, Amir; Li, Li; Verma, Shiv Prakash; Wang, Shuxin; Barrott, Jared J.; Nelson, Mary L.; Yu, Jamie S. E.; Negri, Gian Luca; Colborne, Shane; Hughes, Christopher S.; Zhu, Ju-Fen; Lambert, Sydney L.; Carroll, Lara S.; Smith-Fry, Kyllie; Stewart, Michael G.; Kannan, Sarmishta; Jensen, Bodrie; John, Cini M.; Sikdar, Saif; Liu, Hongrui; Dang, Ngoc Ha; Bourdage, Jennifer; Li, Jinxiu; Vahrenkamp, Jeffery M.; Mortenson, Katelyn L.; Groundland, John S.; Wustrack, Rosanna; Senger, Donna L.; Zemp, Franz J.; Mahoney, Douglas J.; Gertz, Jason; Zhang, Xiaoyang; Lazar, Alexander J.; Hirst, Martin; Morin, Gregg B.; Nielsen, Torsten O.; Shen, Peter S.; Jones, Kevin B. Share Save
One-pot DTECT enables rapid and efficient capture of genetic signatures for precision genome editing and clinical diagnostics Baudrier, Lou; Benamozig, Orlena; Langley, Jethro; Chopra, Sanchit; Kalashnikova, Tatiana; Benaoudia, Sacha; Singh, Gurpreet; Mahoney, Douglas J.; Wright, Nicola A. M.; Billon, Pierre Share Save
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Adverse Events and Serological Responses After SARS-CoV-2 Vaccination in Individuals With Inflammatory Bowel Disease Markovinovic, Ante; Quan, Joshua; Herauf, Michelle; Hracs, Lindsay; Windsor, Joseph W.; Sharifi, Nastaran; Coward, Stephanie; Caplan, Lea; Gorospe, Julia; Ernest-Suarez, Kenneth; Ma, Christopher; Panaccione, Remo; Ingram, Richard J. M.; Kanji, Jamil N.; Tipples, Graham; Holodinsky, Jessalyn K.; Bernstein, Charles N.; Mahoney, Douglas J.; Bernatsky, Sasha; Benchimol, Eric I.; Kaplan, Gilaad G. Share Save
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