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Applications of machine learning in drug discovery and development Vamathevan, Jessica; Clark, Dominic; Czodrowski, Paul; Dunham, Ian; Ferran, Edgardo; Lee, George; Li, Bin; Madabhushi, Anant; Shah, Parantu; Spitzer, Michaela; Zhao, Shanrong Share Save
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TRIM28 and Interacting KRAB-ZNFs Control Self-Renewal of Human Pluripotent Stem Cells through Epigenetic Repression of Pro-differentiation Genes Oleksiewicz, Urszula; Gladych, Marta; Raman, Ayush T.; Heyn, Holger; Mereu, Elisabetta; Chlebanowska, Paula; Andrzejewska, Anastazja; Sozanska, Barbara; Samant, Neha; Fak, Katarzyna; Auguscik, Paulina; Kosinski, Marcin; Wroblewska, Joanna P.; Tomczak, Katarzyna; Kulcenty, Katarzyna; Ploski, Rafal; Biecek, Przemyslaw; Esteller, Manel; Shah, Parantu K.; Rai, Kunal; Wiznerowicz, Maciej Share Save
In Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer Carugo, Alessandro; Genovese, Giannicola; Seth, Sahil; Nezi, Luigi; Rose, Johnathon Lynn; Bossi, Daniela; Cicalese, Angelo; Shah, Parantu Krushnakant; Viale, Andrea; Pettazzoni, Piergiorgio Francesco; Akdemir, Kadir Caner; Bristow, Christopher Aaron; Robinson, Frederick Scott; Tepper, James; Sanchez, Nora; Gupta, Sonal; Estecio, Marcos Roberto; Giuliani, Virginia; Dellino, Gaetano Ivan; Riva, Laura; Yao, Wantong; Di Francesco, Maria Emilia; Green, Tessa; D'Alesio, Carolina; Corti, Denise; Kang, Ya'an; Jones, Philip; Wang, Huamin; Fleming, Jason Bates; Maitra, Anirban; Pelicci, Pier Giuseppe; Chin, Lynda; DePinho, Ronald Anthony; Lanfrancone, Luisa; Heffernan, Timothy Paul; Draetta, Giulio Francesco Share Save
Applying TCGA data for breast cancer diagnostics and pathway analysis Andersen, Jannik; Shah, Parantu; Ibbs, Matthew; Filas, Violetta; Korski, Konstanty; Marszalek, Andrzej; Wu, Yuanqing; Chang, Edward; Toniatti, Carlo; Draetta, Giulio; Wiznerowicz, Maciej Share Save
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The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNFMutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies Vangamudi, Bhavatarini; Paul, Thomas A.; Shah, Parantu K.; Kost-Alimova, Maria; Nottebaum, Lisa; Shi, Xi; Zhan, Yanai; Leo, Elisabetta; Mahadeshwar, Harshad S.; Protopopov, Alexei; Futreal, Andrew; Tieu, Trang N.; Peoples, Mike; Heffernan, Timothy P.; Marszalek, Joseph R.; Toniatti, Carlo; Petrocchi, Alessia; Verhelle, Dominique; Owen, Dafydd R.; Draetta, Giulio; Jones, Philip; Palmer, Wylie S.; Sharma, Shikhar; Andersen, Jannik N. Share Save
The SMARCA2/4 catalytic activity, but not the bromodomain, is a drug target in SWI/SNF mutant cancers Vangamudi, Bhavatarini; Paui, Thomas; Shah, Parantu K.; Alimova, Maria K.; Nottebaum, Lisa; Shi, Xi; Zhan, Yanai; Leo, Elisabetta; Mahadeshwar, Harshad S.; Protopopov, Alexei; Futreal, Andrew; Tieu, Trang N.; Peoples, Mike; Petrocchi, Alessia; Marszalek, Joseph R.; Toniatti, Carlo; Heffernan, Timothy P.; Verhelle, Dominique; Draetta, Giulio; Owen, Dafydd; Jones, Philip; Palmer, Wylie; Sharma, Shikhar; Andersen, Jannik N. Share Save
Genetic Events That Limit the Efficacy of MEK and RTK Inhibitor Therapies in a Mouse Model of KRAS-Driven Pancreatic Cancer Pettazzoni, Piergiorgio; Viale, Andrea; Shah, Parantu; Carugo, Alessandro; Ying, Haoqiang; Wang, Huamin; Genovese, Giannicola; Seth, Sahil; Minelli, Rosalba; Green, Tessa; Huang-Hobbs, Emmet; Corti, Denise; Sanchez, Nora; Nezi, Luigi; Marchesini, Matteo; Kapoor, Avnish; Yao, Wantong; Di Francesco, Maria E.; Petrocchi, Alessia; Deem, Angela K.; Scott, Kenneth; Colla, Simona; Mills, Gordon B.; Fleming, Jason B.; Heffernan, Timothy P.; Jones, Philip; Toniatti, Carlo; DePinho, Ronald A.; Draetta, Giulio F. Share Save
Applying TCGA data for breast cancer diagnostics and pathway analysis Andersen, Jannik; Shah, Parantu; Korski, Konstanty; Ibbs, Matthew; Filas, Violetta; Kosiedowski, Michal; Pukacki, Juliusz; Mazurek, Cezary; Wu, Yuanqing; Chang, Edward; Toniatti, Carlo; Draetta, Giulio; Wiznerowicz, Maciej Share Save
Targeting Poly(ADP-Ribose) Polymerase and the c-Myb-Regulated DNA Damage Response Pathway in Castration-Resistant Prostate Cancer Li, Likun; Chang, Wenjun; Yang, Guang; Ren, Chengzhen; Park, Sanghee; Karantanos, Theodoros; Karanika, Styliani; Wang, Jianxiang; Yin, Jianhua; Shah, Parantu K.; Takahiro, Hirayama; Dobashi, Masato; Zhang, Wenling; Efstathiou, Eleni; Maity, Sankar N.; Aparicio, Ana M.; Tapia, Elsa M. Li Ning; Troncoso, Patricia; Broom, Bradley; Xiao, Lianchun; Lee, Hyun-Sung; Lee, Ju-Seog; Corn, Paul G.; Navone, Nora; Thompson, Timothy C. Share Save
Gene expression profile alone is inadequate in predicting complete response in multiple myeloma Amin, S. B.; Yip, W-K; Minvielle, S.; Broyl, A.; Li, Y.; Hanlon, B.; Swanson, D.; Shah, P. K.; Moreau, P.; van der Holt, B.; van Duin, M.; Magrangeas, F.; Sonneveld, P. Pieter; Anderson, K. C.; Li, C.; Avet-Loiseau, H.; Munshi, N. C. Share Save
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Integrative analysis of gene and miRNA expression profiles with transcription factor-miRNA feed-forward loops identifies regulators in human cancers Yan, Zhenyu; Shah, Parantu K.; Amin, Samir B.; Samur, Mehmet K.; Huang, Norman; Wang, Xujun; Misra, Vikas; Ji, Hongbin; Gabuzda, Dana; Li, Cheng Share Save
A Comprehensive Map of Insulator Elements for the Drosophila Genome Negre, Nicolas; Brown, Christopher D.; Shah, Parantu K.; Kheradpour, Pouya; Morrison, Carolyn A.; Henikoff, Jorja G.; Feng, Xin; Ahmad, Kami; Russell, Steven; White, Robert A. H.; Stein, Lincoln; Henikoff, Steven; Kellis, Manolis; White, Kevin P. Share Save
Genomic analysis of estrogen cascade reveals histone variant H2A.Z associated with breast cancer progression Hua, Sujun; Kallen, Caleb B.; Dhar, Ruby; Baquero, Maria T.; Mason, Christopher E.; Russell, Beth A.; Shah, Parantu K.; Liu, Jiang; Khramtsov, Andrey; Tretiakova, Maria S.; Krausz, Thomas N.; Olopade, Olufunmilayo I.; Rimm, David L.; White, Kevin P. Share Save
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