Philip A. Watson - Publications, H-index & Citations

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Philip A. Watson

Memorial Sloan Kettering Cancer Center

23H-index

99Paper Count

8.0KCitation Count

Published Papers 25

Publication Date

Single- cell analysis of treatment- resistant prostate cancer: Implications of cell state changes for cell surface antigen- targeted therapies

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-07-05

OAAI

Zaidi, Samir; Park, Jooyoung; Chan, Joseph M.; Roudier, Martine P.; Zhao, Jimmy L.; Gopalan, Anuradha; Wadosky, Kristine M.; Patel, Radhika A.; Sayar, Erolcan; Karthaus, Wouter R.; Kates, D. Henry; Chaudhary, Ojasvi; Xu, Tianhao; Masilionis, Ignas; Mazutis, Linas; Chaligne, Ronan; Obradovic, Aleksandar; Linkov, Irina; Barlas, Afsar; Jungbluth, Achim A.; Rekhtman, Natasha; Silber, Joachim; Manova-Todorova, Katia; Watson, Philip A.; True, Lawrence D.; Morrissey, Colm; Scher, Howard I.; Rathkopf, Dana E.; Morris, Michael J.; Goodrich, David W.; Choi, Jungmin; Nelson, Peter S.; Haffner, Michael C.; Sawyers, Charles L.

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Targeting prostate tumor low-molecular weight tyrosine phosphatase for oxidation-sensitizing therapy

SCIENCE ADVANCES

IF12.5

2024-02-02

OAAI

Stanford, Stephanie M.; Nguyen, Tiffany P.; Chang, Joseph; Zhao, Zixuan; Hackman, G. Lavender; Santelli, Eugenio; Sanders, Colton M.; Katiki, Madhusudhanarao; Dondossola, Eleonora; Brauer, Brooke L.; Diaz, Michael A.; Zhan, Yuan; Ramsey, Sterling H.; Watson, Philip A.; Sankaran, Banumathi; Paindelli, Claudia; Parietti, Vanessa; Mikos, Antonios G.; Lodi, Alessia; Bagrodia, Aditya; Elliott, Andrew; Mckay, Rana R.; Murali, Ramachandran; Tiziani, Stefano; Kettenbach, Arminja N.; Bottini, Nunzio

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Allosteric interactions prime androgen receptor dimerization and activation

MOLECULAR CELL

IF16.6

2022-06-01

OAAI

Wasmuth, Elizabeth V.; Vanden Broeck, Arnaud; LaClair, Justin R.; Hoover, Elizabeth A.; Lawrence, Kayla E.; Paknejad, Navid; Pappas, Kyrie; Matthies, Doreen; Wang, Biran; Feng, Weiran; Watson, Philip A.; Zinder, John C.; Karthaus, Wouter R.; de la Cruz, M. Jason; Hite, Richard K.; Manova-Todorova, Katia; Yu, Zhiheng; Weintraub, Susan T.; Klinge, Sebastian; Sawyers, Charles L.

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The protein phosphatase 4 complex is a tumor suppressor in prostate cancer

CANCER RESEARCH

IF16.6

2020-08-15

PREAI

Watson, Philip A.; Lawrence, Kayla E.; Nadkarni, Tejasveeta, V; Ishmael, Taslima F.; Lee, Eugine; Rivera, Aura C. Agudelo; Love, Jillian R.; Wongvipat, John; Cai, Ling; Nazir, Abbas; Iaquinta, Phillip J.; Chang, Kenneth; Liang, Yupu; Hannon, Greg J.; Sawyers, Charles L.

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Somatic Tissue Engineering in Mouse Models Reveals an Actionable Role for WNT Pathway Alterations in Prostate Cancer Metastasis

CANCER DISCOVERY

IF33.3

2020-07-01

OAAI

Leibold, Josef; Ruscetti, Marcus; Cao, Zhen; Ho, Yu-Jui; Baslan, Timour; Zou, Min; Abida, Wassim; Feucht, Judith; Han, Teng; Barriga, Francisco M.; Tsanov, Kaloyan M.; Zamechek, Leah; Kulick, Amanda; Amor, Corina; Tian, Sha; Rybczyk, Katarzyna; Salgado, Nelson R.; Sanchez-Rivera, Francisco J.; Watson, Philip A.; de Stanchina, Elisa; Wilkinson, John E.; Dow, Lukas E.; Abate-Shen, Cory; Sawyers, Charles L.; Lowe, Scott W.

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Modeling biological and genetic diversity in upper tract urothelial carcinoma with patient derived xenografts

NATURE COMMUNICATIONS

IF15.7

2020-04-24

OAAI

Kim, Kwanghee; Hu, Wenhuo; Audenet, Francois; Almassi, Nima; Hanrahan, Aphrothiti J.; Murray, Katie; Bagrodia, Aditya; Wong, Nathan; Clinton, Timothy N.; Dason, Shawn; Mohan, Vishnu; Jebiwott, Sylvia; Nagar, Karan; Gao, Jianjiong; Penson, Alex; Hughes, Chris; Gordon, Benjamin; Chen, Ziyu; Dong, Yiyu; Watson, Philip A.; Alvim, Ricardo; Elzein, Arijh; Gao, Sizhi P.; Cocco, Emiliano; Santin, Alessandro D.; Ostrovnaya, Irina; Hsieh, James J.; Sagi, Irit; Pietzak, Eugene J.; Hakimi, A. Ari; Rosenberg, Jonathan E.; Iyer, Gopa; Vargas, Herbert A.; Scaltriti, Maurizio; Al-Ahmadie, Hikmat; Solit, David B.; Coleman, Jonathan A.

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Tumor microenvironment derived NRG1 promotes antiandrogen resistance in prostate cancer

CANCER RESEARCH

IF16.6

2019-07-01

OAAI

Zhang, Zeda; Karthaus, Wouter; Mota, Jose Mauricio; Mu, Ping; Wu, Chao; Abida, Wassim; Linton, Eliot; Lee, Young Sun; Lee, Eugine; Mao, Ninghui; Adams, Elizabeth; Choi, Danielle; Rathkopf, Dana E.; Carver, Brett; Gopalan, Anuradha; Jiang, Xuejun; Watson, Philip; Sawyers, Charles

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GREB1 amplifies androgen receptor output in human prostate cancer and contributes to antiandrogen resistance

ELIFE

IF0

2019-01-15

OAAI

Lee, Eugine; Wongvipat, John; Choi, Danielle; Wang, Ping; Lee, Young Sun; Zheng, Deyou; Watson, Philip A.; Gopalan, Anuradha; Sawyers, Charles L.

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Feed-forward alpha particle radiotherapy ablates androgen receptor-addicted prostate cancer

NATURE COMMUNICATIONS

IF15.7

2018-04-24

OAAI

McDevitt, Michael R.; Thorek, Daniel L. J.; Hashimoto, Takeshi; Gondo, Tatsuo; Veach, Darren R.; Sharma, Sai Kiran; Kalidindi, Teja Muralidhar; Abou, Diane S.; Watson, Philip A.; Beattie, Bradley J.; Timmermand, Oskar Vilhemsson; Strand, Sven-Erik; Lewis, Jason S.; Scardino, Peter T.; Scher, Howard I.; Lilja, Hans; Larson, Steven M.; Ulmert, David

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SOX2 promotes lineage plasticity and antiandrogen resistance in TP53 and RB1 deficient prostate cancer

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Mu, Ping; Zhang, Zeda; Benelli, Matteo; Karthaus, Wouter; Hoover, Elizebeth; Chen, Chi-Chao; Wongvipat, John; Ku, Sheng-Yu; Gao, Dong; Cao, Zhen; Shah, Neel; Adams, Elizabeth; Abida, Wassim; Watson, Philip; Prandi, Davide; Huang, Chun-Hao; de Stanchina, Elisa; Lowe, Scott; Ellis, Leigh; Beltran, Himisha; Rubin, Mark; Goodrich, David; Demichelis, Francesca; Sawyers, Charles L.

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Internalization of secreted antigen-targeted antibodies by the neonatal Fc receptor for precision imaging of the androgen receptor axis

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2016-11-30

OAAI

Thorek, Daniel L. J.; Watson, Philip A.; Lee, Sang-Gyu; Ku, Anson T.; Bournazos, Stylianos; Braun, Katharina; Kim, Kwanghee; Sjostrom, Kjell; Doran, Michael G.; Lamminmaki, Urpo; Santos, Elmer; Veach, Darren; Turkekul, Mesruh; Casey, Emily; Lewis, Jason S.; Abou, Diane S.; van Voss, Marise R. H.; Scardino, Peter T.; Strand, Sven-Erik; Alpaugh, Mary L.; Scher, Howard I.; Lilja, Hans; Larson, Steven M.; Ulmert, David

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Androgen insensitivity syndrome germline loss-of-function mutations in the androgen receptor that acquire somatic gain-of-function in prostate cancer

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Watson, Philip A.; Balbas, Minna D.; Zhang, Zeda; Ishmael, Taslima F.; Lawrence, Kayla E.; Wongvipat, John; Sawyers, Sophie D.; Wu, Yi-Mi; Robinson, Dan; Shen, Yang; Chinnaiyan, Arul M.; Sawyers, Charles L.

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Loss of function mutations of an ETS repressor expand the ETS positive subset of prostate cancer

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Bose, Rohit; Abida, Wassim; Karthaus, Wouter; Armenia, Joshua; Iaquinta, Phillip; Wongvipat, John; Doran, Michael; Hieronymus, Haley; Watson, Philip; Sullivan, Patrick; Liang, Yupu; Schultz, Nikolaus; Sawyers, Charles

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Androgen deprivation therapy potentiates the efficacy of vascular targeted photodynamic therapy of prostate cancer xenografts

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Kim, Kwanghee; Watson, Philip A.; Jebiwott, Sylvia; Somma, Alexander J.; La Rosa, Stephen P.; Mehta, Dipti; Murray, Katie S.; Lilja, Hans; Ulmert, David; Scherz, Avigdor; Coleman, Jonathan

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Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer

NATURE REVIEWS CANCER

IF66.8

2015-11-13

1.1K

OAAI

Watson, Philip A.; Arora, Vivek K.; Sawyers, Charles L.

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Annotating STEAP1 Regulation in Prostate Cancer with 89Zr Immuno-PET

JOURNAL OF NUCLEAR MEDICINE

IF9.1

2014-11-05

OAAI

Doran, Michael G.; Watson, Philip A.; Cheal, Sarah M.; Spratt, Daniel E.; Wongvipat, John; Steckler, Jeffrey M.; Carrasquillo, Jorge A.; Evans, Michael J.; Lewis, Jason S.

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Androgen Receptor Signaling Regulates DNA Repair in Prostate Cancers

CANCER DISCOVERY

IF33.3

2013-11-06

464

OAAI

Polkinghorn, William R.; Parker, Joel S.; Lee, Man X.; Kass, Elizabeth M.; Spratt, Daniel E.; Iaquinta, Phillip J.; Arora, Vivek K.; Yen, Wei-Feng; Cai, Ling; Zheng, Deyou; Carver, Brett S.; Chen, Yu; Watson, Philip A.; Shah, Neel P.; Fujisawa, Sho; Goglia, Alexander G.; Gopalan, Anuradha; Hieronymus, Haley; Wongvipat, John; Scardino, Peter T.; Zelefsky, Michael J.; Jasin, Maria; Chaudhuri, Jayanta; Powell, Simon N.; Sawyers, Charles L.

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Overcoming mutation-based resistance to antiandrogens with rational drug design

ELIFE

IF0

2013-04-09

377

OAAI

Balbas, Minna D.; Evans, Michael J.; Hosfield, David J.; Wongvipat, John; Arora, Vivek K.; Watson, Philip A.; Chen, Yu; Greene, Geoffrey L.; Shen, Yang; Sawyers, Charles L.

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Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2010-09-07

613

OAAI

Watson, Philip A.; Chen, Yinan F.; Balbas, Minna D.; Wongvipat, John; Socci, Nicholas D.; Viale, Agnes; Kim, Kwanghee; Sawyers, Charles L.

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Epidermal growth factor receptor vIII expression in U87 glioblastoma cells alters their proteasome composition, function, and response to irradiation

MOLECULAR CANCER RESEARCH

IF4.7

2008-03-12

OAAI

Kim, Kwanghee; Brush, James M.; Watson, Philip A.; Cacalano, Nicholas A.; Iwamoto, Keisuke S.; McBride, William H.

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Research Directions