Dhanesh Amarnani - Publications, H-index & Citations

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Dhanesh Amarnani

Harvard University

14H-index

39Paper Count

1.3KCitation Count

Published Papers 12

Publication Date

An mRNA-encoded dominant-negative inhibitor of transcription factor RUNX1 suppresses vitreoretinal disease in experimental models

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2024-11-27

PREAI

O'Hare, Michael; Miller, William P.; Arevalo-Alquichire, Said; Amarnani, Dhanesh; Apryani, Evhy; Perez-Corredor, Paula; Marino, Claudia; Shu, Daisy Y.; Vanderleest, Timothy E.; Muriel-Torres, Andres; Gordon, Harper B.; Gunawan, Audrey L.; Kaplan, Bryan A.; Barake, Karim W.; Bejjani, Romy P.; Doan, Tri H.; Lin, Rose; Delgado-Tirado, Santiago; Gonzalez-Buendia, Lucia; Rossin, Elizabeth J.; Zhao, Guannan; Eliott, Dean; Weinl-Tenbruck, Christine; Chevessier-Tuennesen, Frederic; Rejman, Joanna; Montrasio, Fabio; Kim, Leo A.; Arboleda-Velasquez, Joseph F.

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Resilience to autosomal dominant Alzheimer's disease in a Reelin-COLBOS heterozygous man

NATURE MEDICINE

IF50

2023-05-15

OAAI

Lopera, Francisco; Marino, Claudia; Chandrahas, Anita S.; O'Hare, Michael; Villalba-Moreno, Nelson David; Aguillon, David; Baena, Ana; Sanchez, Justin S.; Vila-Castelar, Clara; Ramirez Gomez, Liliana; Chmielewska, Natalia; Oliveira, Gabriel M.; Littau, Jessica Lisa; Hartmann, Kristin; Park, Kyungeun; Krasemann, Susanne; Glatzel, Markus; Schoemaker, Dorothee; Gonzalez-Buendia, Lucia; Delgado-Tirado, Santiago; Arevalo-Alquichire, Said; Saez-Torres, Kahira L.; Amarnani, Dhanesh; Kim, Leo A.; Mazzarino, Randall C.; Gordon, Harper; Bocanegra, Yamile; Villegas, Andres; Gai, Xiaowu; Bootwalla, Moiz; Ji, Jianling; Shen, Lishuang; Kosik, Kenneth S.; Su, Yi; Chen, Yinghua; Schultz, Aaron; Sperling, Reisa A.; Johnson, Keith; Reiman, Eric M.; Sepulveda-Falla, Diego; Arboleda-Velasquez, Joseph F.; Quiroz, Yakeel T.

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Topical Nanoemulsion of a Runt-related Transcription Factor 1 Inhibitor for the Treatment of Pathologic Ocular Angiogenesis

OPHTHALMOLOGY SCIENCE

IF4.6

2022-09-01

OAAI

Delgado-Tirado, Santiago; Gonzalez-Buendia, Lucia; An, Miranda; Amarnani, Dhanesh; Isaacs-Bernal, Daniela; Whitmore, Hannah; Arevalo-Alquichire, Said; Leyton-Cifuentes, David; Ruiz-Moreno, Jose M.; Arboleda-Velasquez, Joseph F.; Kim, Leo A.

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Topical delivery of a small molecule RUNX1 transcription factor inhibitor for the treatment of proliferative vitreoretinopathy

SCIENTIFIC REPORTS

IF3.9

2020-11-30

OAAI

Delgado-Tirado, Santiago; Amarnani, Dhanesh; Zhao, Guannan; Rossin, Elizabeth J.; Eliott, Dean; Miller, John B.; Greene, Whitney A.; Ramos, Leslie; Arevalo-Alquichire, Said; Leyton-Cifuentes, David; Gonzalez-Buendia, Lucia; Isaacs-Bernal, Daniela; Whitmore, Hannah A. B.; Chmielewska, Natalia; Duffy, Brandon V.; Kim, Eric; Wang, Heuy-Ching; Ruiz-Moreno, Jose M.; Kim, Leo A.; Arboleda-Velasquez, Joseph F.

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TNF-α signaling regulates RUNX1 function in endothelial cells

FASEB JOURNAL

IF4.2

2020-11-02

OAAI

Whitmore, Hannah A. B.; Amarnani, Dhanesh; O'Hare, Michael; Delgado-Tirado, Santiago; Gonzalez-Buendia, Lucia; An, Miranda; Pedron, Julien; Bushweller, John H.; Arboleda-Velasquez, Joseph F.; Kim, Leo A.

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Resistance to autosomal dominant Alzheimer's disease in an APOE3 Christchurch homozygote: a case report

NATURE MEDICINE

IF50

2019-11-04

367

OAAI

Arboleda-Velasquez, Joseph F.; Lopera, Francisco; O'Hare, Michael; Delgado-Tirado, Santiago; Marino, Claudia; Chmielewska, Natalia; Saez-Torres, Kahira L.; Amarnani, Dhanesh; Schultz, Aaron P.; Sperling, Reisa A.; Leyton-Cifuentes, David; Chen, Kewei; Baena, Ana; Aguillon, David; Rios-Romenets, Silvia; Giraldo, Margarita; Guzman-Velez, Edmarie; Norton, Daniel J.; Pardilla-Delgado, Enmanuelle; Artola, Arabiye; Sanchez, Justin S.; Acosta-Uribe, Juliana; Lalli, Matthew; Kosik, Kenneth S.; Huentelman, Matthew J.; Zetterberg, Henrik; Blennow, Kaj; Reiman, Rebecca A.; Luo, Ji; Chen, Yinghua; Thiyyagura, Pradeep; Su, Yi; Jun, Gyungah R.; Naymik, Marcus; Gai, Xiaowu; Bootwalla, Moiz; Ji, Jianling; Shen, Lishuang; Miller, John B.; Kim, Leo A.; Tariot, Pierre N.; Johnson, Keith A.; Reiman, Eric M.; Quiroz, Yakeel T.

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Effect of Methotrexate on an In Vitro Patient-Derived Model of Proliferative Vitreoretinopathy

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2017-08-04

OAAI

Amarnani, Dhanesh; Machuca-Parra, Arturo Israel; Wong, Lindsay L.; Marko, Christina K.; Stefater, James A.; Stryjewski, Tomasz P.; Eliott, Dean; Arboleda-Velasquez, Joseph E.; Kim, Leo A.

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Therapeutic antibody targeting of Notch3 signaling prevents mural cell loss in CADASIL

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2017-07-11

OAAI

Machuca-Parra, Arturo I.; Bigger-Allen, Alexander A.; Sanchez, Angie V.; Boutabla, Anissa; Cardona-Velez, Jonathan; Amarnani, Dhanesh; Saint-Geniez, Magali; Siebel, Christian W.; Kim, Leo A.; D'Amore, Patricia A.; Arboleda-Velasquez, Joseph F.

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Identification of RUNX1 as a Mediator of Aberrant Retinal Angiogenesis

DIABETES

IF7.5

2017-04-11

OAAI

Lam, Jonathan D.; Oh, Daniel J.; Wong, Lindsay L.; Amarnani, Dhanesh; Park-Windhol, Cindy; Sanchez, Angie V.; Cardona-Velez, Jonathan; McGuone, Declan; Stemmer-Rachamimov, Anat O.; Eliott, Dean; Bielenberg, Diane R.; van Zyl, Tave; Shen, Lishuang; Gai, Xiaowu; D'Amore, Patricia A.; Kim, Leo A.; Arboleda-Velasquez, Joseph F.

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Oxidized Lipoprotein Uptake Through the CD36 Receptor Activates the NLRP3 Inflammasome in Human Retinal Pigment Epithelial Cells

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2016-09-08

OAAI

Gnanaguru, Gopalan; Choi, Ariel R.; Amarnani, Dhanesh; D'Amore, Patricia A.

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Orbital Angiogenesis and Lymphangiogenesis in Thyroid Eye Disease An Analysis of Vascular Growth Factors with Clinical Correlation

OPHTHALMOLOGY

IF9.5

2016-09-01

OAAI

Wong, Lindsay L.; Lee, Nahyoung Grace; Amarnani, Dhanesh; Choi, Catherine J.; Bielenberg, Diane R.; Freitag, Suzanne K.; D'Amore, Patricia A.; Kim, Leo A.

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Tamoxifen Toxicity in Cultured Retinal Pigment Epithelial Cells Is Mediated by Concurrent Regulated Cell Death Mechanisms

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2014-08-04

OAAI

Kim, Leo A.; Amarnani, Dhanesh; Gnanaguru, Gopalan; Tseng, Wen Allen; Vavvas, Demetrios G.; D'Amore, Patricia A.

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Research Directions