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S

Sophia Y. Tsai

Baylor College of Medicine

98H-index
353Paper Count
3.3WCitation Count
Published Papers 95
Publication Date
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Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err222
errOAAI
errLi, XT; Wong, JM; Tsai, SY; Tsai, MJ; O'Malley, BW
errShare
errSave
Selective estrogen receptor modulators 4-hydroxytamoxifen and raloxifene impact the stability and function of SRC-1 and SRC-3 coactivator proteins
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err80
errOAAI
errLonard, DM; Tsai, SY; O'Malley, BW
errShare
errSave
Dynamic cell type specificity of SRC-1 coactivator in modulating uterine progesterone receptor function in mice
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err44
errOAAI
errHan, SJ; Jeong, J; DeMayo, FJ; Xu, JM; Tsai, SY; Tsai, MJ; O'Malley, BW
errShare
errSave
Role of the steroid receptor coactivator SRC-3 in cell growth
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err120
errOAAI
errZhou, G; Hashimoto, Y; Kwak, I; Tsai, SY; Tsai, MJ
errShare
errSave
Cdc25B functions as a novel coactivator for the steroid receptors
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err51
errOAAI
errMa, ZQ; Liu, Z; Ngan, ESW; Tsai, SY
errShare
errSave
Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1)
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err99
errOAAI
errYi, P; Wu, RC; Sandquist, J; Wong, JM; Tsai, SY; Tsai, MJ; Means, AR; O'Malley, BW
errShare
errSave
The nuclear orphan receptor COUP-TFII is required for limb and skeletal muscle development
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err67
errOAAI
errLee, CT; Li, LP; Takamoto, N; Martin, JF; DeMayo, FJ; Tsai, MJ; Tsai, SY
errShare
errSave
Specific amino acid residues in the basic helix-loop-helix domain of SRC-3 are essential for its nuclear localization and proteasome-dependent turnover
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err44
errOAAI
errLi, Chao; Wu, Ray-Chang; Amazit, Larbi; Tsai, Sophia Y.; Tsai, Ming-Jer; O'Malley, Bert W.
errShare
errSave
Bmp2 is critical for the murine uterine decidual response
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err327
errOAAI
errLee, Kevin Y.; Jeong, Jae-Wook; Wang, Jinrong; Ma, Lijiang; Martin, James F.; Tsai, Sophia Y.; Lydon, John P.; DeMayo, Francesco J.
errShare
errSave
Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAG-3/TRAM-1) coactivator activity by IκB kinase
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err263
errOAAI
errWu, RC; Qin, J; Hashimoto, Y; Wong, J; Xu, J; Tsai, SY; Tsai, MJ; O'Malley, BW
errShare
errSave
E2/Estrogen Receptor/Sjogren Syndrome-Associated Autoantigen Relieves Coactivator Activator-Induced G1/S Arrest To Promote Breast Tumorigenicity
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err2
errOAAI
errKang, Yun Kyoung; Jung, Sung Yun; Qin, Jun; Li, Chao; Tsai, Sophia Y.; Tsai, Ming-Jer; O'Malley, Bert W.
errShare
errSave
Elevated COUP-TFII expression in dopaminergic neurons accelerates the progression of Parkinson's disease through mitochondrial dysfunction
errPLOS GENETICS
IF3.7
err2020-06-24
err16
errOAAI
errKao, Chung-Yang; Xu, Mafei; Wang, Leiming; Lin, Shih-Chieh; Lee, Hui-Ju; Duraine, Lita; Bellen, Hugo J.; Goldstein, David S.; Tsai, Sophia Y.; Tsai, Ming-Jer
errShare
errSave
Opposing Functions of BRD4 Isoforms in Breast Cancer
errMOLECULAR CELL
IF16.6
err2020-06-01
err107
errOAAI
errWu, Shwu-Yuan; Lee, Chien-Fei; Lai, Hsien-Tsung; Yu, Cheng-Tai; Lee, Ji-Eun; Zuo, Hao; Tsai, Sophia Y.; Tsai, Ming-Jer; Ge, Kai; Wan, Yihong; Chiang, Cheng-Ming
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errSave
Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment
errSCIENCE ADVANCES
IF12.5
err2020-05-01
err18
errOAAI
errWang, Leiming; Cheng, Chiang-Min; Qin, Jun; Xu, Mafei; Kao, Chung-Yang; Shi, Jingjing; You, Erli; Gong, Wanchun; Rosa, Laura Pedro; Chase, Peter; Scampavia, Louis; Madoux, Franck; Spicer, Timothy; Hodder, Peter; Xu, H. Eric; Tsai, Sophia Y.; Tsai, Ming-Jer
errShare
errSave
Small molecule JQ1 promotes prostate cancer invasion via BET-independent inactivation of FOXA1
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2020-03-03
err55
errOAAI
errWang, Leiming; Xu, Mafei; Kao, Chung-Yang; Tsai, Sophia Y.; Tsai, Ming-Jer
errShare
errSave
Nuclear receptors regulate alternative lengthening of telomeres through a novel noncanonical FANCD2 pathway
errSCIENCE ADVANCES
IF12.5
err2019-10-11
err19
errOAAI
errXu, Mafei; Qin, Jun; Wang, Leiming; Lee, Hui-Ju; Kao, Chung-Yang; Liu, Dan; Zhou Songyang; Chen, Junjie; Tsai, Ming-Jer; Tsai, Sophia Y.
errShare
errSave
SRC-3 Coactivator Governs Dynamic Estrogen-Induced Chromatin Looping Interactions during Transcription
errMOLECULAR CELL
IF16.6
err2018-05-01
err30
errOAAI
errPanigrahi, Anil K.; Foulds, Charles E.; Lanz, Rainer B.; Hamilton, Ross A.; Yi, Ping; Lonard, David M.; Tsai, Ming-Jer; Tsai, Sophia Y.; O'Malley, Bert W.
errShare
errSave
Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2017-09-01
err195
errOAAI
errGates, Leah A.; Shi, Jiejun; Rohira, Aarti D.; Feng, Qin; Zhu, Bokai; Bedford, Mark T.; Sagum, Cari A.; Jung, Sung Yun; Qin, Jun; Tsai, Ming-Jer; Tsai, Sophia Y.; Li, Wei; Foulds, Charles E.; O'Malley, Bert W.
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errSave
Dysregulation of nuclear receptor COUP-TFII impairs skeletal muscle development
errSCIENTIFIC REPORTS
IF3.9
err2017-06-09
err22
errOAAI
errLee, Hui-Ju; Kao, Chung-Yang; Lin, Shih-Chieh; Xu, Mafei; Xie, Xin; Tsai, Sophia Y.; Tsai, Ming-Jer
errShare
errSave
Decreased epithelial progesterone receptor A at the window of receptivity is required for preparation of the endometrium for embryo attachment
errBIOLOGY OF REPRODUCTION
IF3
err2017-01-24
err71
errOAAI
errWetendorf, Margeaux; Wu, San-Pin; Wang, Xiaoqiu; Creighton, Chad J.; Wang, Tianyuan; Lanz, Rainer B.; Blok, Leen; Tsai, Sophia Y.; Tsai, Ming-Jer; Lydon, John P.; DeMayo, Francesco J.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
R
Richard A. Gibbs
H-index: 190 · Papers: 1.3K
J
Johan Auwerx
H-index: 183 · Papers: 913
B
Bert W. O’Malley
H-index: 160 · Papers: 1.4K
D
Donna M. Muzny
H-index: 156 · Papers: 693
I
Ignacio I. Wistuba
H-index: 153 · Papers: 2.8K
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