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I

Igor Chernukhin

Cancer Research UK Cambridge Institute

27H-index
86Paper Count
3.3KCitation Count
Published Papers 37
Publication Date
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Evaluating progesterone receptor agonist megestrol plus letrozole for women with early-stage estrogen-receptor-positive breast cancer: the window-of-opportunity, randomized, phase 2b, PIONEER trial
errNature Cancer
IF28.5
err2026-01-05
err0
errOAAI
errRebecca A. Burrell; Sanjeev Kumar; Elena Provenzano; Cleopatra Pike; Alimu Dayimu; Stuart A. McIntosh; Vassilis Pitsinis; Polly King; Beatrix Elsberger; Sasi Govindarajulu; Lucy Satherley; Sirwan Hadad; Peter Schmid; Amit Agrawal; Bodiere Akpuluma; Steven Bell; John R. Benson; Carlos Caldas; Danya Cheeseman; Igor Chernukhin; Parto Forouhi; Tulay Gulsen; Eleftheria Kleidi; Karen Pinilla; Wendi Qian; Jean E. Abraham; Jason S. Carroll; Richard D. Baird
errShare
errSave
Transcription factor switching drives subtype-specific pancreatic cancer
errNature Genetics
IF29
err2025-10-30
err0
errOAAI
errShalini V. Rao; Lisa Young; Danya Cheeseman; Sean Flynn; Niklas Krebs; Dominique-Laurent Couturier; Stephanie Mack; Rebecca Brais; Jill Temple; Amy Smith; Evangelia Papachristou; Catarina Pelicano; Chandra Sekhar Reddy Chilamakuri; Krzysztof Herka; Hideo Baba; Luay Farah; Phyllis F. Cheung; Jens Siveke; Stéphane Guerrier; Luca Insolia; Michael Gill; Emily Archer Goode; Steven Kupczak; Yi Cheng; Giacomo Borsari; Duncan Jodrell; Clive D’Santos; Alasdair Russell; Barbara T. Grünwald; Eva Serrao; Igor Chernukhin; Jason S. Carroll
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errSave
C071Transcription factor switching drives progression of the classical subtype of pancreatic cancer
errCANCER RESEARCH
IF16.6
err2024-09-15
err0
PREAI
errRao, Shalini Vasudev; Young, Lisa V.; Cheeseman, Danya; Mack, Stephanie V.; Couturier, Dominique-Laurent; Flynn, Sean V.; Brias, Rebecca; Smith, Amy; Temple, Jill; Jodrell, Duncan; Russell, Alasdair V. Russell; Chernukhin, Igor; Carroll, Jason
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Results of the window-of-opportunity PIONEER trial evaluating addition of the progesterone receptor (PR) agonist megestrol to letrozole for early stage estrogen receptor (ER) positive breast cancer: exploiting ER-PR interaction
errCANCER RESEARCH
IF16.6
err2024-05-02
err0
PREAI
errBurrell, Rebecca; Kumar, Sanjeev; McIntosh, Stuart; Pitsinis, Vassilis; King, Polly; Elsberger, Beatrix; Govindarajulu, Sasirekha; Satherley, Lucy; Hadad, Sirwan; Schmid, Peter; Abraham, Jean; Agrawal, Amit; Benson, John; Cheeseman, Danya; Chernukhin, Igor; Forouhi, Parto; Kleidi, Eleftheria; Pike, Cleopatra; Pinilla, Karen; Provenzano, Elena; Qian, Wendi; Carroll, Jason; Baird, Richard
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errSave
New insights into the role of FOXA1-HNF4 axis in pancreatic cancer
errCANCER RESEARCH
IF16.6
err2024-01-16
err0
PREAI
errRao, Shalini V.; Young, Lisa; Cheeseman, Danya; Mack, Stephanie; Temple, Jill; Chilamakuri, Chandra Shekar Reddy; Papachristou, Evangelia; Pelicano, Catherina; Smith, Amy; Couturier, Dominique-Laurent; Gill, Michael; Jodrell, Duncan Jodrell; Russell, Alasdair; Chernukhin, Igor; Carroll, Jason
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errSave
Unravelling the epigenetic landscape of pancreatic cancer: The role of cancer-associated fibroblasts
errCANCER RESEARCH
IF16.6
err2024-01-16
err0
PREAI
errPelicano, Catarina; Chernukhin, Igor; Young, Lisa; Vranas, Naomi; Cheng, Yi; Kent, Joshua; Kishore, Kamal; D'Santos, Clive; Russell, Alasdair; Biffi, Giulia; Rao, Shalivi V.; Carroll, Jason S.
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CTCF interacts with and recruits the largest subunit of RNA polymerase II to CTCF target sites genome-wide
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err171
errOAAI
errChernukhin, Igor; Shamsuddin, Shaharum; Kang, Sung Yun; Bergstrom, Rosita; Kwon, Yoo-Wook; Yu, WenQiang; Whitehead, Joanne; Mukhopadhyay, Rituparna; Docquier, France; Farrar, Dawn; Morrison, Ian; Vigneron, Marc; Wu, Shwu-Yuan; Chiang, Cheng-Ming; Loukinov, Dmitri; Lobanenkov, Victor; Ohlsson, Rolf; Klenova, Elena
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errSave
Mutational Analysis of the Poly(ADP-Ribosyl)ation Sites of the Transcription Factor CTCF Provides an Insight into the Mechanism of Its Regulation by Poly(ADP-Ribosyl)ation
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err83
errOAAI
errFarrar, Dawn; Rai, Sushma; Chernukhin, Igor; Jagodic, Maja; Ito, Yoko; Yammine, Samer; Ohlsson, Rolf; Murrell, Adele; Klenova, Elena
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errSave
Elevated ASCL1 activity creates de novo regulatory elements associated with neuronal differentiation
errBMC GENOMICS
IF3.7
err2022-04-03
err24
errOAAI
errWoods, Laura M.; Ali, Fahad R.; Gomez, Roshna; Chernukhin, Igor; Marcos, Daniel; Parkinson, Lydia M.; Abou Tayoun, Ahmad N.; Carroll, Jason S.; Philpott, Anna
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errSave
Estrogen receptor beta repurposes EZH2 to suppress oncogenic NFκB/p65 signaling in triple negative breast cancer
errNPJ BREAST CANCER
IF7.6
err2022-02-17
err12
errOAAI
errAspros, Kirsten G. M.; Carter, Jodi M.; Hoskin, Tanya L.; Suman, Vera J.; Subramaniam, Malayannan; Emch, Michael J.; Ye, Zhenqing; Sun, Zhifu; Sinnwell, Jason P.; Thompson, Kevin J.; Tang, Xiaojia; Rodman, Esther P. B.; Wang, Xiyin; Nelson, Adam W.; Chernukhin, Igor; Hamdan, Feda H.; Bruinsma, Elizabeth S.; Carroll, Jason S.; Fernandez-Zapico, Martin E.; Johnsen, Steven A.; Kalari, Krishna R.; Huang, Haojie; Leon-Ferre, Roberto A.; Couch, Fergus J.; Ingle, James N.; Goetz, Matthew P.; Hawse, John R.
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errSave
TET2 is a component of the estrogen receptor complex and controls 5mC to 5hmC conversion at estrogen receptor cis-regulatory regions
errCELL REPORTS
IF6.9
err2021-02-01
err26
errOAAI
errBroome, Rebecca; Chernukhin, Igor; Jamieson, Stacey; Kishore, Kamal; Papachristou, Evangelia K.; Mao, Shi-Qing; Tejedo, Carmen Gonzalez; Mahtey, Areeb; Theodorou, Vasiliki; Groen, Arnoud J.; D'Santos, Clive; Balasubramanian, Shankar; Farcas, Anca Madalina; Siersbaek, Rasmus; Carroll, Jason S.
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errSave
Dephosphorylation of the Proneural Transcription Factor ASCL1 Re-Engages a Latent Post-Mitotic Differentiation Program in Neuroblastoma
errMOLECULAR CANCER RESEARCH
IF4.7
err2020-12-02
err15
errOAAI
errAli, Fahad R.; Marcos, Daniel; Chernukhin, Igor; Woods, Laura M.; Parkinson, Lydia M.; Wylie, Luke A.; Papkovskaia, Tatiana D.; Davies, John D.; Carroll, Jason S.; Philpott, Anna
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errSave
The proapoptotic gene interferon regulatory factor-1 mediates the antiproliferative outcome of paired box 2 gene and tamoxifen
errONCOGENE
IF7.3
err2020-08-25
err3
errOAAI
errWang, Shixiong; Somisetty, Venkata S.; Bai, Baoyan; Chernukhin, Igor; Niskanen, Henri; Kaikkonen, Minna U.; Bellet, Meritxell; Carroll, Jason S.; Hurtado, Antoni
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errSave
The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver
errONCOGENE
IF7.3
err2020-06-25
err11
errOAAI
errHruschka, Natascha; Kalisz, Mark; Subijana, Maria; Grana-Castro, Osvaldo; Del Cano-Ochoa, Francisco; Brunet, Laia Pare; Chernukhin, Igor; Sagrera, Ana; De Reynies, Aurelien; Kloesch, Bernhard; Chin, Suet-Feung; Burgues, Octavio; Andreu, David; Bermejo, Begona; Cejalvo, Juan Miguel; Sutton, Joe; Caldas, Carlos; Ramon-Maiques, Santiago; Carroll, Jason S.; Prat, Aleix; Real, Francisco X.; Martinelli, Paola
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errSave
Estrogen receptor beta repurposes EZH2 to inhibit oncogenic NFκB signaling in triple negative breast cancer
errCANCER RESEARCH
IF16.6
err2020-02-15
err0
PREAI
errAspros, Kirsten G. M.; Nelson, Adam W.; Ye, Zhenqing; Sun, Zhifu; Chernukhin, Igor; Carroll, Jason S.; Ingle, James N.; Goetz, Matthew P.; Hawse, John R.
errShare
errSave
ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response (vol 87, pg 925, 2020)
errNATURE GENETICS
IF31.8
err2020-01-31
err5
errOAAI
errNagarajan, Sankari; Rao, Shalini V.; Sutton, Joseph; Cheeseman, Danya; Dunn, Shanade; Papachristou, Evangelia K.; Prada, Jose-Enrique Gonzalez; Couturier, Dominique-Laurent; Kumar, Sanjeev; Kishore, Kamal; Chilamakuri, Chandra Sekhar Reddy; Glont, Silvia-Elena; Goode, Emily Archer; Brodie, Cara; Guppy, Naomi; Natrajan, Rachael; Bruna, Alejandra; Caldas, Carlos; Russell, Alasdair; Siersbaek, Rasmus; Yusa, Kosuke; Chernukhin, Igor; Carroll, Jason S.
errShare
errSave
ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response
errNATURE GENETICS
IF31.8
err2020-01-06
err120
errOAAI
errNagarajan, Sankari; Rao, Shalini V.; Sutton, Joseph; Cheeseman, Danya; Dunn, Shanade; Papachristou, Evangelia K.; Prada, Jose-Enrique Gonzalez; Couturier, Dominique-Laurent; Kumar, Sanjeev; Kishore, Kamal; Chilamakuri, Chandra Sekhar Reddy; Glont, Silvia-Elena; Archer Goode, Emily; Brodie, Cara; Guppy, Naomi; Natrajan, Rachael; Bruna, Alejandra; Caldas, Carlos; Russell, Alasdair; Siersbaek, Rasmus; Yusa, Kosuke; Chernukhin, Igor; Carroll, Jason S.
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errSave
Comprehensive Genomic Analysis Reveals that the Pioneering Function of FOXA1 Is Independent of Hormonal Signaling
errCELL REPORTS
IF6.9
err2019-03-01
err45
errOAAI
errGlont, Silvia-E.; Chernukhin, Igor; Carroll, Jason S.
errShare
errSave
Estrogen receptor beta elicits anti-cancer effects in triple negative breast cancer through suppression of NFκB signaling
errCANCER RESEARCH
IF16.6
err2019-02-15
err1
PREAI
errAspros, K.; Nelson, A.; Ye, Z.; Sun, Z.; Chernukhin, I.; Carroll, J.; Ingle, J.; Goetz, M.; Hawse, J.
errShare
errSave
Profiling of advanced glycation end products uncovers abiotic stress-specific target proteins in Arabidopsis
errJOURNAL OF EXPERIMENTAL BOTANY
IF5.7
err2018-11-05
err17
errOAAI
errChaplin, Amanda K.; Chernukhin, Igor; Bechtold, Ulrike
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
C
Carlos Caldas
H-index: 158 · Papers: 1.4K
A
Andrew P. Feinberg
H-index: 121 · Papers: 487
F
Fergus J. Couch
H-index: 119 · Papers: 1.3K
S
Shankar Balasubramanian
H-index: 118 · Papers: 521
R
R. Adron Harris
H-index: 100 · Papers: 629
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