Not logged inLocoregionally delivered PD-1 blockade augments B7-H3 targeting CAR T cell efficacy in models of glioblastoma
Khan, Jonathan; Abrahimi, Parwiz; Cai, Winson; Dong, Lauren; Yu, Kenny Kwok-Hei; Verma, Svena; Marouf, Yacine; Budhu, Sadna; Bah, Mamadou; Miranda, Ileana; Tabar, Viviane; Wolchok, Jedd; Merghoub, Taha; Brentjens, Renier .png)
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SavePharmacologic LDH inhibition redirects intratumoral glucose uptake and improves antitumor immunity in solid tumor modelsVerma, Svena; Budhu, Sadna; Serganova, Inna; Dong, Lauren; Mangarin, Levi M.; Khan, Jonathan F.; Bah, Mamadou A.; Assouvie, Anais; Marouf, Yacine; Schulze, Isabell; Zappasodi, Roberta; Wolchok, Jedd D.; Merghoub, Taha Share Save Targeting oxygen consumption with metformin and phenformin have differential effects on immune cells in the tumor microenvironmentBudhu, Sadna; Assouvie, Anais; Bah, Mamadou; Verma, Svena; Serganova, Inna; Mane, Mayuresh; Zurita, Juan; Koutcher, Jason; Ponomarev, Vladimir; Wolchok, Jedd D.; Merghoub, Taha Share Save Share Save Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccineGigoux, Mathieu; Holmstrom, Morten O.; Zappasodi, Roberta; Park, Joseph J.; Pourpe, Stephane; Bozkus, Cansu Cimen; Mangarin, Levi M. B.; Redmond, David; Verma, Svena; Schad, Sara; George, Mariam M.; Venkatesh, Divya; Ghosh, Arnab; Hoyos, David; Molvi, Zaki; Kamaz, Baransel; Marneth, Anna E.; Duke, William; Leventhal, Matthew J.; Jan, Max; Ho, Vincent T.; Hobbs, Gabriela S.; Knudsen, Trine Alma; Skov, Vibe; Kjaer, Lasse; Larsen, Thomas Stauffer; Hansen, Dennis Lund; Lindsley, R. Coleman; Hasselbalch, Hans; Grauslund, Jacob H.; Lisle, Thomas L.; Met, Ozcan; Wilkinson, Patrick; Greenbaum, Benjamin; Sepulveda, Manuel A.; Chan, Timothy; Rampal, Raajit; Andersen, Mads H.; Abdel-Wahab, Omar; Bhardwaj, Nina; Wolchok, Jedd D.; Mullally, Ann; Merghoub, Taha Share Save MHC-I SKEWING IN MUTANT CALRETICULIN-POSITIVE MYELOPROLIFERATIVE NEOPLASMS IS COUNTERED BY HETEROCLITIC PEPTIDE CANCER VACCINATIONGigoux, Mathieu; Zappasodi, Roberta; Park, Joseph; Pourpe, Stephane; Ghosh, Arnab; Bozkus, Cansu Cimen; Mangarin, Levi; Redmond, David; Verma, Svena; Schad, Sara; Duke, William; Jan, Max; Leventhal, Matthew; Ho, Vincent; Hobbs, Gabriela; Knudsen, Trine Alma; Skov, Vibe; Kjaer, Lasse; Larsen, Thomas Stauffer; Hansen, Dennis Lund; Lindsley, R. Coleman; Hasselbalch, Hans; Grauslund, Jacob; Andersen, Mads; Holmstrom, Morten; Chan, Timothy; Rampal, Raajit; Abdel-Wahab, Omar; Bhardwaj, Nina; Wolchok, Jedd; Mullally, Ann; Merghoub, Taha Share Save CTLA-4 blockade drives loss of regulatory T cell functional stability in glycolysis defective tumorsZappasodi, Roberta; Serganova, Inna; Cohen, Ivan; Maeda, Masatomo; Shindo, Masahiro; Senbabaoglu, Yasin; Leftin, Avigdor; Maniyar, Rachana; Verma, Svena; Lubin, Matthew; Ko, Myat Kyaw; Mane, Mayuresh M.; Ghosh, Arnab; Ackerstaff, Ellen; Koutcher, Jason A.; Ho, Ping-Chih; Delgoffe, Greg M.; Blasberg, Ronald; Wolchok, Jedd D.; Merghoub, Taha Share Save 
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