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G

Gen‐Sheng Feng

Institute of Cancer Research

69H-index
277Paper Count
1.8WCitation Count
Published Papers 139
Publication Date
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Advancing liver cancer immunotherapy beyond checkpoint blockade
errScience China-Life Sciences
IF9.5
err2026-03-11
err0
PREAI
errGen-Sheng Feng
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errSave
Rapamycin Reverses the Hepatic Response to Diet-Induced Metabolic Stress That Is Amplified by Aging
errAging Cell
IF7.1
err2026-02-07
err0
errOAAI
errAaron Havas; Adarsh Rajesh; Xue Lei; Jessica Proulx; Karl N. Miller; Adam Field; Andrew Davis; Marcos Garcia Teneche; Armin Gandhi; Jin Lee; Gen-Sheng Feng; Peter D. Adams
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Efficacious suppression of primary and metastasized liver tumors by polyIC-loaded lipid nanoparticles
errHEPATOLOGY
IF15.8
err2025-09-01
err1
PREAI
errLiu, Yingluo; Wang, Xinyi; Krishnan, Nishta; Hsiao, Timothy; Ji, Yichun; Kaneko, Kota; Teneche, Marcos G.; Adams, Peter D.; Zuniga, Elina; Kaech, Susan M.; Zhang, Liangfang; Feng, Gen-Sheng
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PolyIC as an adjuvant outperforms anti-VEGF in combination with anti-PD-L1 therapy in mouse liver tumor models
errHepatology Communications
IF4.6
err2025-08-15
err0
errOAAI
errJi, Yichun; Lu, Li-Chun; Zhuang, Hao; Liu, Yingluo; Gao, Yiming; Qin, Andre; Lee, Jin; Feng, Gen-Sheng
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errSave
Author Correction: ImAge quantitates aging and rejuvenation
errNature Aging
IF19.4
err2025-08-05
err0
PREAI
errMartin Alvarez-Kuglen; Kenta Ninomiya; Haodong Qin; Delany Rodriguez; Lorenzo Fiengo; Chen Farhy; Wei-Mien Hsu; Brian Kirk; Aaron Havas; Collin Kaufman; Gen-Sheng Feng; Amanda J. Roberts; Rozalyn M. Anderson; Manuel Serrano; Peter D. Adams; Tatyana O. Sharpee; Alexey V. Terskikh
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Targeting chondrocytes for arresting bony fusion in ankylosing spondylitis (vol 12, 6540 , 2021)
errNATURE COMMUNICATIONS
IF15.7
err2025-02-07
err0
errOAAI
errShao, Fenli; Liu, Qianqian; Zhu, Yuyu; Fan, Zhidan; Chen, Wenjun; Liu, Shijia; Li, Xiaohui; Guo, Wenjie; Feng, Gen-Sheng; Yu, Haiguo; Xu, Qiang; Sun, Yang
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errSave
ImAge quantitates aging and rejuvenation
errNATURE AGING
IF19.4
err2024-08-29
err2
PREAI
errAlvarez-Kuglen, Martin; Ninomiya, Kenta; Qin, Haodong; Rodriguez, Delany; Fiengo, Lorenzo; Farhy, Chen; Hsu, Wei-Mien; Kirk, Brian; Havas, Aaron; Feng, Gen-Sheng; Roberts, Amanda J.; Anderson, Rozalyn M.; Serrano, Manuel; Adams, Peter D.; Sharpee, Tatyana O.; Terskikh, Alexey V.
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errSave
Genomic and transcriptomic analyses of chemical hepatocarcinogenesis aggravated by oncoprotein loss
errHEPATOLOGY
IF15.8
err2024-07-30
err1
PREAI
errWang, Xinyi; Liu, Yingluo; Zhang, Shuo; Zhang, Jiemeng; Lin, Xiaoxue; Liang, Yan; Zong, Min; Hanley, Kaisa L.; Lee, Jin; Karin, Michael; Feng, Gen-Sheng
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errSave
The most impactful findings on liver cancer in 2023
errHEPATOLOGY COMMUNICATIONS
IF4.6
err2024-04-01
err0
errOAAI
errLee, Jin; Hanley, Kaisa L.; Feng, Gen-Sheng
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errSave
Genomic and transcriptomic analyses of chemical hepatocarcinogenesis aggravated by loss of oncoproteins in hepatocytes
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errWang, Xinyi; Zhang, Jiemeng; Liu, Yingluo; Zhang, Shuo; Liang, Yan; Zong, Min; Lin, Xiaoxue; Karin, Michael; Feng, Gensheng
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errSave
NCOA5 Deficiency in Macrophages Provokes NASH and HCC
errCELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
IF7.4
err2024-01-01
err0
errOAAI
errLiu, Yingluo; Feng, Gen-sheng
errShare
errSave
Deciphering a critical role of uterine epithelial SHP2 in parturition initiation at single cell resolution
errNATURE COMMUNICATIONS
IF15.7
err2023-11-14
err1
errOAAI
errLiu, Meng; Ji, Mengjun; Cheng, Jianghong; Li, Yingzhe; Tian, Yingpu; Zhao, Hui; Wang, Yang; Zhu, Sijing; Zhang, Leilei; Xu, Xinmei; Feng, Gen-Sheng; Liang, Xiaohuan; Bao, Haili; Tang, Yedong; Kong, Shuangbo; Lu, Jinhua; Wang, Haibin; Lu, Zhongxian; Deng, Wenbo
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Identification of CD133+ intercellsomes in intercellular communication to offset intracellular signal deficit
errELIFE
IF0
err2023-10-17
err2
errOAAI
errKaneko, Kota; Liang, Yan; Liu, Qing; Zhang, Shuo; Scheiter, Alexander; Song, Dan; Feng, Gen-Sheng
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errSave
Pharmaceutical SH2 domain-containing protein tyrosine phosphatase 2 inhibition suppresses primary and metastasized liver tumors by provoking hepatic innate immunity
errHEPATOLOGY
IF15.8
err2023-04-17
err8
errOAAI
errLiu, Jacey J.; Xin, Bing; Du, Li; Chen, Lydia; Long, Yanyan; Feng, Gen-Sheng
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errSave
A deletion mutation in the SH2-N domain of Shp-2 severely suppresses hematopoietic cell development
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-29
err167
errOAAI
errQu, CK; Shi, ZQ; Shen, R; Tsai, FY; Orkin, SH; Feng, GS
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errSave
Molecular mechanism for the Shp-2 tyrosine phosphatase function in promoting growth factor stimulation of Erk activity
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err228
errOAAI
errShi, ZQ; Yu, DH; Park, M; Marshall, M; Feng, GS
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errSave
Biased suppression of hematopoiesis and multiple developmental defects in chimeric mice containing Shp-2 mutant cells
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err126
errOAAI
errQu, CK; Yu, WM; Azzarelli, B; Cooper, S; Broxmeyer, HE; Feng, GS
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errSave
Concerted functions of Gab1 and Shp2 in liver regeneration and hepatoprotection
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err105
errOAAI
errBard-Chapeau, Emilie A.; Yuan, Jing; Droin, Nathalie; Long, Shinong; Zhang, Eric E.; Nguyen, Thanh V.; Feng, Gen-Sheng
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errSave
Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err361
errOAAI
errYou, M; Yu, DH; Feng, GS
errShare
errSave
Grap negatively regulates T-cell receptor-elicited lymphocyte proliferation and interleukin-2 induction
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err47
errOAAI
errShen, R; Quyang, YB; Qu, CK; Alonso, A; Sperzel, L; Mustelin, T; Kaplan, MH; Feng, GS
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
M
Michael Karin
H-index: 254 · Papers: 902
C
Christopher K. Glass
H-index: 170 · Papers: 569
R
Roger J. Davis
H-index: 166 · Papers: 852
C
C. Ronald Kahn
H-index: 164 · Papers: 635
T
Tony Pawson
H-index: 157 · Papers: 751
View more