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10 Year Follow-up of CALGB 10603/Ratify: Midostaurin Versus Placebo Plus Intensive Chemotherapy in Newly Diagnosed FLT3 Mutant Acute Myeloid Leukemia Patients Aged 18-60 Years Stone, Richard M.; Yin, Jun; Mandrekar, Sumithra J.; Benner, Axel; Saadati, Maral; Galinsky, Ilene A.; Sanford, Ben L.; Teske, Rebecca; Geyer, Susan M.; Prior, Thomas; Amadori, Sergio; Appelbaum, Frederick R.; Brandwein, Joseph; Dohner, Konstanze; Ehninger, Gerhard; Ganser, Arnold; Klisovic, Rebecca B.; Krauter, Jurgen; Marcucci, Guido; Medeiros, Bruno; Niederwieser, Dietger W.; Sanz, Miguel A.; Schlenk, Richard F.; Serve, Hubert; Sierra, Jorge; Tallman, Martin S.; Wei, Andrew H.; Witte, Theo J. M. de; Thiede, Christian; Doehner, Hartmut; Larson, Richard A. Share Save
Time from diagnosis to treatment has no impact on survival in newly diagnosed acute myeloid leukemia treated with venetoclax-based regimens Baden, David; Zukunft, Sven; Hernandez, Gema; Wolgast, Nadine; Steinhaeuser, Sophie; Pohlmann, Alexander; Schliemann, Christoph; Mikesch, Jan-Henrik; Steffen, Bjoern; Sauer, Tim; Hanoun, Maher; Schaefer-Eckart, Kerstin; Krause, Stefan W.; Haenel, Mathias; Einsele, Hermann; Jost, Edgar; Bruemmendorf, Tim H.; Scholl, Sebastian; Hochhaus, Andreas; Neubauer, Andreas; Burchert, Andreas; Kaufmann, Martin; Niemann, Dirk; Schaich, Markus; Blau, Wolfgang; Kiani, Alexander; Goerner, Martin; Kaiser, Ulrich; Kullmer, Johannes; Weber, Thomas; Berdel, Wolfgang E.; Ehninger, Gerhard; Mueller-Tidow, Carsten; Platzbecker, Uwe; Serve, Hubert; Bornhaeuser, Martin; Roellig, Christoph; Baldus, Claudia D.; Fransecky, Lars Share Save
Prognostic impact of CEBPA mutational subgroups in adult AML Georgi, Julia-Annabell; Stasik, Sebastian; Kramer, Michael; Meggendorfer, Manja; Roellig, Christoph; Haferlach, Torsten; Valk, Peter; Linch, David; Herold, Tobias; Duployez, Nicolas; Taube, Franziska; Middeke, Jan Moritz; Platzbecker, Uwe; Serve, Hubert; Baldus, Claudia D.; Muller-Tidow, Carsten; Haferlach, Claudia; Koch, Sarah; Berdel, Wolfgang E.; Woermann, Bernhard J.; Krug, Utz; Braess, Jan; Hiddemann, Wolfgang; Spiekermann, Karsten; Boertjes, Emma L.; Hills, Robert K.; Burnett, Alan; Ehninger, Gerhard; Metzeler, Klaus; Rothenberg-Thurley, Maja; Dufour, Annika; Dombret, Herve; Pautas, Cecile; Preudhomme, Claude; Fenwarth, Laurene; Bornhaeuser, Martin; Gale, Rosemary; Thiede, Christian Share Save
Mutated IKZF1 is an independent marker of adverse risk in acute myeloid leukemia Eckardt, Jan-Niklas; Stasik, Sebastian; Roellig, Christoph; Petzold, Andreas; Sauer, Tim; Scholl, Sebastian; Hochhaus, Andreas; Crysandt, Martina; Bruemmendorf, Tim H.; Naumann, Ralph; Steffen, Bjoern; Kunzmann, Volker; Einsele, Hermann; Schaich, Markus; Burchert, Andreas; Neubauer, Andreas; Schaefer-Eckart, Kerstin; Schliemann, Christoph; Krause, Stefan W.; Herbst, Regina; Haenel, Mathias; Hanoun, Maher; Kaiser, Ulrich; Kaufmann, Martin; Racil, Zdenek; Mayer, Jiri; Oelschlaegel, Uta; Berdel, Wolfgang E.; Ehninger, Gerhard; Serve, Hubert; Mueller-Tidow, Carsten; Platzbecker, Uwe; Baldus, Claudia D.; Dahl, Andreas; Schetelig, Johannes; Bornhaeuser, Martin; Middeke, Jan Moritz; Thiede, Christian Share Save
UBTF tandem duplications are rare but recurrent alterations in adult AML and associated with younger age, myelodysplasia, and inferior outcome Georgi, Julia-Annabell; Stasik, Sebastian; Eckardt, Jan-Niklas; Zukunft, Sven; Hartwig, Marita; Roellig, Christoph; Middeke, Jan Moritz; Oelschlaegel, Uta; Krug, Utz; Sauer, Tim; Scholl, Sebastian; Hochhaus, Andreas H.; Bruemmendorf, Tim; Naumann, Ralph; Steffen, Bjoern; Einsele, Hermann; Schaich, Markus; Burchert, Andreas; Neubauer, Andreas; Schaefer-Eckart, Kerstin; Schliemann, Christoph W.; Krause, Stefan; Haenel, Mathias; Noppeney, Richard; Kaiser, Ulrich D.; Baldus, Claudia; Kaufmann, Martin; Mueller-Tidow, Carsten; Platzbecker, Uwe E.; Berdel, Wolfgang; Serve, Hubert; Ehninger, Gerhard; Bornhaeuser, Martin; Schetelig, Johannes; Kroschinsky, Frank; Thiede, Christian Share Save
Midostaurin in addition to intensive chemotherapy in acute myeloid leukemia with t(8;21) and KIT and/or FLT3-ITD mutations: results of the SAL MIDOKIT trial Ruhnke, Leo; Roellig, Christoph; Herold, Sylvia; Sauer, Tim; Brandts, Christian H.; Steffen, Bjoern; Schaefer-Eckart, Kerstin; Krause, Stefan W.; Haenel, Mathias; Reichle, Albrecht; Scholl, Sebastian; Neubauer, Andreas; Mikesch, Jan-Henrik; Schetelig, Johannes; Stoelzel, Friedrich; Kramer, Michael; Haake, Annett; Frimmel, Julia; Kraemer, Alwin; Schlenk, Richard; Platzbecker, Uwe; Serve, Hubert; Baldus, Claudia D.; Mueller-Tidow, Carsten; Aust, Daniela; Bornhaeuser, Martin; Ehninger, Gerhard; Thiede, Christian Share Save
Impact of IDH1 and IDH2 mutational subgroups in AML patients after allogeneic stem cell transplantation Kunadt, Desiree; Stasik, Sebastian; Metzeler, Klaus H.; Roellig, Christoph; Schliemann, Christoph; Greif, Philipp A.; Spiekermann, Karsten; Rothenberg-Thurley, Maja; Krug, Utz; Braess, Jan; Kraemer, Alwin; Hochhaus, Andreas; Scholl, Sebastian; Hilgendorf, Inken; Bruemmendorf, Tim H.; Jost, Edgar; Steffen, Bjoern; Bug, Gesine; Einsele, Hermann; Goerlich, Dennis; Sauerland, Cristina; Schaefer-Eckart, Kerstin; Krause, Stefan W.; Haenel, Mathias; Hanoun, Maher; Kaufmann, Martin; Woermann, Bernhard; Kramer, Michael; Sockel, Katja; Egger-Heidrich, Katharina; Herold, Tobias; Ehninger, Gerhard; Burchert, Andreas; Platzbecker, Uwe; Berdel, Wolfgang E.; Mueller-Tidow, Carsten; Hiddemann, Wolfgang; Serve, Hubert; Stelljes, Matthias; Baldus, Claudia D.; Neubauer, Andreas; Schetelig, Johannes; Thiede, Christian; Bornhaeuser, Martin; Middeke, Jan M.; Stoelzel, Friedrich Share Save
Genomic landscape of patients with FLT3-mutated acute myeloid leukemia (AML) treated within the CALGB 10603/RATIFY trial Jahn, Nikolaus; Jahn, Ekaterina; Saadati, Maral; Bullinger, Lars; Larson, Richard A.; Ottone, Tiziana; Amadori, Sergio; Prior, Thomas W.; Brandwein, Joseph M.; Appelbaum, Frederick R.; Medeiros, Bruno C.; Tallman, Martin S.; Ehninger, Gerhard; Heuser, Michael; Ganser, Arnold; Pallaud, Celine; Gathmann, Insa; Krzykalla, Julia; Benner, Axel; Bloomfield, Clara D.; Thiede, Christian; Stone, Richard M.; Doehner, Hartmut; Doehner, Konstanze Share Save
Deep sequencing in CD34+ cells from peripheral blood enables sensitive detection of measurable residual disease in AML Stasik, Sebastian; Burkhard-Meier, Clara; Kramer, Michael; Middeke, Jan M.; Oelschlaegel, Uta; Sockel, Katja; Ehninger, Gerhard; Serve, Hubert; Mueller-Tidow, Carsten; Baldus, Claudia D.; Roellig, Christoph; Bornhaeuser, Martin; Platzbecker, Uwe; Thiede, Christian Share Save
Molecular profiling and clinical implications of patients with acute myeloid leukemia and extramedullary manifestations Eckardt, Jan-Niklas; Stoelzel, Friedrich; Kunadt, Desiree; Roellig, Christoph; Stasik, Sebastian; Wagenfuehr, Lisa; Joehrens, Korinna; Kuithan, Friederike; Kraemer, Alwin; Scholl, Sebastian; Hochhaus, Andreas; Crysandt, Martina; Brummendorf, Tim H.; Naumann, Ralph; Steffen, Bjoern; Kunzmann, Volker; Einsele, Hermann; Schaich, Markus; Burchert, Andreas; Neubauer, Andreas; Schaefer-Eckart, Kerstin; Schliemann, Christoph; Krause, Stefan W.; Herbst, Regina; Haenel, Mathias; Hanoun, Maher; Kaiser, Ulrich; Kaufmann, Martin; Racil, Zdenek; Mayer, Jiri; Kroschinsky, Frank; Berdel, Wolfgang E.; Ehninger, Gerhard; Serve, Hubert; Mueller-Tidow, Carsten; Platzbecker, Uwe; Baldus, Claudia D.; Schetelig, Johannes; Bornhauser, Martin; Thiede, Christian; Middeke, Jan Moritz Share Save
Point Mutations in the FLT3-ITD Region Are Rare but Recurrent Alterations in Adult AML and Associated With Concomitant KMT2A-PTD Stasik, Sebastian; Kramer, Michael; Zukunft, Sven; Rollig, Christoph; Baldus, Claudia D.; Platzbecker, Uwe; Serve, Hubert; Muller-Tidow, Carsten; Schafer-Eckart, Kerstin; Kaufmann, Martin; Krause, Stefan; Sauer, Tim; Hanel, Mathias; Neubauer, Andreas; Ehninger, Gerhard; Bornhauser, Martin; Schetelig, Johannes; Middeke, Jan M.; Thiede, Christian Share Save
Differential impact of IDH1/2 mutational subclasses on outcome in adult AML: results from a large multicenter study Middeke, Jan M.; Metzeler, Klaus H.; Roellig, Christoph; Kraemer, Michael; Eckardt, Jan-Niklas; Stasik, Sebastian; Greif, Philipp A.; Spiekermann, Karsten; Rothenberg-Thurley, Maja; Krug, Utz; Braess, Jan; Kraemer, Alwin; Hochhaus, Andreas; Bruemmendorf, Tim H.; Naumann, Ralph; Steffen, Bjoern; Einsele, Hermann; Schaich, Markus; Burchert, Andreas; Neubauer, Andreas; Goerlich, Dennis; Sauerland, Cristina; Schaefer-Eckart, Kerstin; Schliemann, Christoph; Krause, Stefan W.; Haenel, Mathias; Frickhofen, Norbert; Noppeney, Richard; Kaiser, Ulrich; Kaufmann, Martin; Kunadt, Desiree; Woermann, Bernhard; Sockel, Katja; von Bonin, Malte; Herold, Tobias; Mueller-Tidow, Carsten; Platzbecker, Uwe; Berdel, Wolfgang E.; Serve, Hubert; Baldus, Claudia D.; Ehninger, Gerhard; Schetelig, Johannes; Hiddemann, Wolfgang; Bornhaeuser, Martin; Stoelzel, Friedrich; Thiede, Christian Share Save
Impact of PTPN11 mutations on clinical outcome analyzed in 1529 patients with acute myeloid leukemia Stasik, Sebastian; Eckardt, Jan-Niklas; Kramer, Michael; Roellig, Christoph; Kraemer, Alwin; Scholl, Sebastian; Hochhaus, Andreas; Crysandt, Martina; Bruemmendorf, Tim H.; Naumann, Ralph; Steffen, Bjorn; Kunzmann, Volker; Einsele, Hermann; Schaich, Markus; Burchert, Andreas; Neubauer, Andreas; Schaefer-Eckart, Kerstin; Schliemann, Christoph; Krause, Stefan; Herbst, Regina; Haenel, Mathias; Frickhofen, Norbert; Noppeney, Richard; Kaiser, Ulrich; Baldus, Claudia D.; Kaufmann, Martin; Racil, Zdenek; Platzbecker, Uwe; Berdel, Wolfgang E.; Mayer, Jiri; Serve, Hubert; Mueller-Tidow, Carsten; Ehninger, Gerhard; Bornhaeuser, Martin; Schetelig, Johannes; Middeke, Jan M.; Thiede, Christian Share Save
Molecular landscape and prognostic impact of FLT3-ITD insertion site in acute myeloid leukemia: RATIFY study results Rucker, Frank G.; Du, Ling; Luck, Tamara J.; Benner, Axel; Krzykalla, Julia; Gathmann, Insa; Voso, Maria Teresa; Amadori, Sergio; Prior, Thomas W.; Brandwein, Joseph M.; Appelbaum, Frederick R.; Medeiros, Bruno C.; Tallman, Martin S.; Savoie, Lynn; Sierra, Jorge; Pallaud, Celine; Sanz, Miguel A.; Jansen, Joop H.; Niederwieser, Dietger; Fischer, Thomas; Ehninger, Gerhard; Heuser, Michael; Ganser, Arnold; Bullinger, Lars; Larson, Richard A.; Bloomfield, Clara D.; Stone, Richard M.; Doehner, Hartmut; Thiede, Christian; Doehner, Konstanze Share Save
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Midostaurin reduces relapse in FLT3-mutant acute myeloid leukemia: the Alliance CALGB 10603/RATIFY trial Larson, Richard A.; Mandrekar, Sumithra J.; Huebner, Lucas J.; Sanford, Ben L.; Laumann, Kristina; Geyer, Susan; Bloomfield, Clara D.; Thiede, Christian; Prior, Thomas W.; Dohner, Konstanze; Marcucci, Guido; Voso, Maria Teresa; Klisovic, Rebecca B.; Galinsky, Ilene; Wei, Andrew H.; Sierra, Jorge; Sanz, Miguel A.; Brandwein, Joseph M.; de Witte, Theo; Niederwieser, Dietger; Appelbaum, Frederick R.; Medeiros, Bruno C.; Tallman, Martin S.; Krauter, Jurgen; Schlenk, Richard F.; Ganser, Arnold; Serve, Hubert; Ehninger, Gerhard; Amadori, Sergio; Gathmann, Insa; Dohner, Hartmut; Stone, Richard M. Share Save
Sorafenib or placebo in patients with newly diagnosed acute myeloid leukaemia: long-term follow-up of the randomized controlled SORAML trial Roellig, Christoph; Serve, Hubert; Noppeney, Richard; Hanoun, Maher; Krug, Utz; Baldus, Claudia D.; Brandts, Christian H.; Kunzmann, Volker; Einsele, Hermann; Kraemer, Alwin; Mueller-Tidow, Carsten; Schaefer-Eckart, Kerstin; Neubauer, Andreas; Burchert, Andreas; Giagounidis, Aristoteles; Krause, Stefan W.; Mackensen, Andreas; Aulitzky, Walter; Herbst, Regina; Haenel, Mathias; Frickhofen, Norbert; Kullmer, Johannes; Kaiser, Ulrich; Kiani, Alexander; Link, Hartmut; Geer, Thomas; Reichle, Albrecht; Junghanss, Christian; Repp, Roland; Meinhardt, Achim; Duerk, Heinz; Klut, Ina-Maria; Bornhaeuser, Martin; Schaich, Markus; Parmentier, Stefani; Goerner, Martin; Thiede, Christian; von Bonin, Malte; Platzbecker, Uwe; Schetelig, Johannes; Kramer, Michael; Berdel, Wolfgang E.; Ehninger, Gerhard Share Save
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