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Melanoma of the Choroid and Ciliary Body in Children: Remission of Metastatic Melanoma of the Choroid After Treatment With Chemotherapy and Immune Checkpoint Inhibition Tuller, Pia; Kiefer, Tobias; Jabbarli, Leyla; Papaioannou, Kyriaki; Schramm, Kathrin; Barwinski, Nicole; Schonberger, Stefan; Brecht, Ines B.; Schneider, Dominik T.; Livingstone, Elisabeth; Zimmer, Lisa; Fischhuber, Karen; Junker, Andreas; Ting, Saskia; Kiewert, Cordula; Goricke, Sophia; Bechrakis, Nikolaos; Biewald, Eva; Ketteler, Petra Share Save
Oncogene aberrations drive medulloblastoma progression, not initiation Okonechnikov, Konstantin; Joshi, Piyush; Koerber, Verena; Rademacher, Anne; Bortolomeazzi, Michele; Mallm, Jan-Philipp; Vaillant, Jan; da Silva, Patricia Benites Goncalves; Statz, Britta; Sepp, Mari; Sarropoulos, Ioannis; Yamada, Tetsuya; Wittmann, Andrea; Schramm, Kathrin; Blattner-Johnson, Mirjam; Fiesel, Petra; Jones, Barbara; Jaeger, Natalie; Pajtler, Kristian W.; van Tilburg, Cornelis M.; Witt, Olaf; Bochennek, Konrad; Weber, Katharina Johanna; Nonnenmacher, Lisa; Reimann, Christian; Ghasemi, David R.; Schueller, Ulrich; Mynarek, Martin; Rutkowski, Stefan; Jones, David T. W.; Korshunov, Andrey; Rippe, Karsten; Westermann, Frank; Thongjuea, Supat; Hoefer, Thomas; Kaessmann, Henrik; Kutscher, Lena M.; Pfister, Stefan M. Share Save
Constitutional variants in PTEN: a frequent finding in patients with papillary tumors of the pineal region subtype B (PTPR-B) associated with isolated loss of chromosome 10 Hirsch, S; Rahmanzade, R; Grund, K; Sutter, C; Schramm, K; Selt, F; Ecker, J; Jones, BC; Schrimpf, D; Demmert, M; Stücklin, ASG; Driever, PH; Mezger, M; Brecht, I; Adib, SD; Brummel, B; Sturm, D; Dikow, N; Hempel, M; Milde, T; Pajtler, K; Jones, DTW; Pfister, SM; von Deimling, A; Sahm, F; Schaaf, CP Share Save
Cerebrospinal fluid liquid biopsy guides differential diagnosis of relapsed medulloblastoma versus secondary glioma: A case report of a pediatric patient enrolled on a PDGFRA inhibitor trial Fischer, Tom T.; Maass, Kendra K.; Schoof, Melanie; Puranachot, Pitithat; Sievers, Philipp; Montigel, Sophia; Fluhr, Theresa; El Damaty, Ahmed; Seitz, Angelika; Harrabi, Semi; Schramm, Kathrin; Sturm, Dominik; Jones, David T. W.; Pfister, Stefan M.; Witt, Olaf; van Tilburg, Cornelis M.; Milde, Till; Schuller, Ulrich; Pajtler, Kristian W. Share Save
Pediatric spinal high-grade glioma in the pediatric precision oncology registry INFORM: Identification of potential therapeutic targets Pfaff, Elke; Schramm, Kathrin; Blattner-Johnson, Mirjam; Jones, Barbara C.; Stark, Sebastian; Balasubramanian, Gnana Prakash; Previti, Christopher; Autry, Robert J.; Fiesel, Petra; Sahm, Felix; Reuss, David; von Deimling, Andreas; van Tilburg, Cornelis M.; Pajtler, Kristian W.; Milde, Till; Dirksen, Uta; Kramm, Christof M.; von Bueren, Andre O.; Munthe-Kaas, Monica C.; Ora, Ingrid; Pfister, Stefan M.; Witt, Olaf; Jones, David T. W. Share Save
Author Correction: A MYCN-driven de-differentiation profile identifies a subgroup of aggressive retinoblastoma Ryl, Tatsiana; Afanasyeva, Elena; Hartmann, Till; Schwermer, Melanie; Schneider, Markus; Schroeder, Christopher; Wagemanns, Maren; Bister, Arthur; Kanber, Deniz; Steenpass, Laura; Schramm, Kathrin; Jones, Barbara; Jones, David T. W.; Biewald, Eva; Astrahantseff, Kathy; Hanenberg, Helmut; Rahmann, Sven; Lohmann, Dietmar R.; Schramm, Alexander; Ketteler, Petra Share Save
A MYCN-driven de-differentiation profile identifies a subgroup of aggressive retinoblastoma Ryl, Tatsiana; Afanasyeva, Elena; Hartmann, Till; Schwermer, Melanie; Schneider, Markus; Schroeder, Christopher; Wagemanns, Maren; Bister, Arthur; Kanber, Deniz; Steenpass, Laura; Schramm, Kathrin; Jones, Barbara; Jones, David T. W.; Biewald, Eva; Astrahantseff, Kathy; Hannenberg, Helmut; Rahmann, Sven; Lohmann, Dietmar R.; Schramm, Alexander; Ketteler, Petra Share Save
GENE REGULATORY NETWORK LANDSCAPE OF GROUP 3/4 MEDULLOBLASTOMA Joshi, Piyush; Stelzer, Tamina; Okonechnikov, Konstantin; Sarropoulos, Ioannis; Sepp, Mari; Pour-Jamnani, Mischan, V; Rademacher, Anne; Yamada-Saito, Tetsuya; Schneider, Celine; Schmidt, Julia; Schaefer, Philipp; Leiss, Kevin; Bortolomeazzi, Michele; Mallm, Jan-Philipp; da Silva, Patricia B. G.; Statz, Britta; Wittmann, Andrea; Schramm, Kathrin; Blattner-Johnson, Mirjam; Fiesel, Petra; Jones, Barbara; Milde, Till; Pajtler, Kristian; van Tilburg, Cornelis M.; Witt, Olaf; Rippe, Karsten; Korshunov, Andrey; Jones, David T. W.; Hovestadt, Volker; Northcott, Paul A.; Thongjuea, Supat; Jaeger, Natalie; Kaessmann, Henrik; Pfister, Stefan M.; Kutscher, Lena M. Share Save
DISTRIBUTION AND MUTATIONAL PATTERNS OF TP53 ALTERATIONS ACROSS SUBTYPES OF PEDIATRIC HIGH-GRADE GLIOMAS Blattner-Johnson, Mirjam; Sturm, Dominik; Hirsch, Steffen; Jones, Barbara; Schramm, Kathrin; Balasubramanian, Gnana Prakash; Sill, Martin; Autry, Robert; Previti, Christopher; van Tilburg, Cornelis M.; Milde, Till; Pajtler, Kristian W.; Sahm, Felix; Kramm, Christof M.; Witt, Olaf; Pfister, Stefan M.; Jones, David T. W. Share Save
DEVELOPMENT OF A FUNCTIONAL PLATFORM FOR REAL-TIME PERSONALIZED DRUG SENSITIVITY PROFILING OF PATIENT-DERIVED 3D FRESH TUMOR TISSUE CULTURES IN THE PEDIATRIC PRECISION ONCOLOGY PROGRAM INFORM Peterziel, Heike; Jamaladdin, Nora; El Harouni, Dina; Gerloff, Xenia F.; Herter, Sonja; Fiesel, Petra; Berker, Yannick; Blattner-Johnson, Mirjam; Schramm, Kathrin; Jones, Barbara C.; Reuss, David; Turunen, Laura; Friedenauer, Aileen; Holland-Letz, Tim; Sill, Martin; Weiser, Lena; Previti, Christopher; Ubramanian, Gnanaprakash Balas; Gerber, Nicolas U.; Gojo, Johannes; Hutter, Caroline; Ora, Ingrid; Lohi, Olli; Kattamis, Antonis; De Wilde, Bram; Termann, Frank Wes; Tippelt, Stephan; Graf, Norbert; Nathrath, Michaela; Sparber-Sauer, Monika; Sehested, Astrid; Kramm, Christof M.; Dirksen, Uta; Kallioniemi, Olli; Pfister, Stefan M.; Van Tilburg, Cornelis M.; Jones, David T. W.; Saarela, Jani; Pietiainen, Vilja; Jager, Natalie; Schlesner, Matthias; Kopp-Schneider, Annette; Oppermann, Sina; Milde, Till; Witt, Olaf; Oehme, Ina Share Save
Genomic ALK alterations in primary and relapsed neuroblastoma Rosswog, Carolina; Fassunke, Jana; Ernst, Angela; Schoemig-Markiefka, Birgid; Merkelbach-Bruse, Sabine; Bartenhagen, Christoph; Cartolano, Maria; Ackermann, Sandra; Theissen, Jessica; Blattner-Johnson, Mirjam; Jones, Barbara; Schramm, Kathrin; Altmueller, Janine; Nuernberg, Peter; Ortmann, Monika; Berthold, Frank; Peifer, Martin; Buettner, Reinhard; Westermann, Frank; Schulte, Johannes H.; Simon, Thorsten; Hero, Barbara; Fischer, Matthias Share Save
Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification (vol 145, pg 49, 2023) Keck, Michaela-Kristina; Sill, Martin; Wittmann, Andrea; Joshi, Piyush; Stichel, Damian; Beck, Pengbo; Okonechnikow, Konstantin; Sievers, Philipp; Wefers, Annika K.; Roncaroli, Federico; Avula, Shivaram; McCabe, Martin G.; Hayden, James T.; Wesseling, Pieter; Ora, Ingrid; Nister, Monica; Kranendonk, Mariette E. G.; Tops, Bastiaan B. J.; Zapotocky, Michal; Zamecnik, Josef; Vasiljevic, Alexandre; Fenouil, Tanguy; Meyronet, David; von Hoff, Katja; Schueller, Ulrich; Loiseau, Hugues; Figarella-Branger, Dominique; Kramm, Christof M.; Sturm, Dominik; Scheie, David; Rauramaa, Tuomas; Pesola, Jouni; Gojo, Johannes; Haberler, Christine; Brandner, Sebastian; Jacques, Tom; Sexton Oates, Alexandra; Saffery, Richard; Koscielniak, Ewa; Baker, Suzanne J.; Yip, Stephen; Snuderl, Matija; Ud Din, Nasir; Samuel, David; Schramm, Kathrin; Blattner-Johnson, Mirjam; Selt, Florian; Ecker, Jonas; Milde, Till; von Deimling, Andreas; Korshunov, Andrey; Perry, Arie; Pfister, Stefan M.; Sahm, Felix; Solomon, David A.; Jones, David T. W. Share Save
Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM Peterziel, Heike; Jamaladdin, Nora; ElHarouni, Dina; Gerloff, Xenia F.; Herter, Sonja; Fiesel, Petra; Berker, Yannick; Blattner-Johnson, Mirjam; Schramm, Kathrin; Jones, Barbara C.; Reuss, David; Turunen, Laura; Friedenauer, Aileen; Holland-Letz, Tim; Sill, Martin; Weiser, Lena; Previti, Christopher; Balasubramanian, Gnanaprakash; Gerber, Nicolas U.; Gojo, Johannes; Hutter, Caroline; Ora, Ingrid; Lohi, Olli; Kattamis, Antonis; de Wilde, Bram; Westermann, Frank; Tippelt, Stephan; Graf, Norbert; Nathrath, Michaela; Sparber-Sauer, Monika; Sehested, Astrid; Kramm, Christof M.; Dirksen, Uta; Kallioniemi, Olli; Pfister, Stefan M.; van Tilburg, Cornelis M.; Jones, David T. W.; Saarela, Jani; Pietiaeinen, Vilja; Jaeger, Natalie; Schlesner, Matthias; Kopp-Schneider, Annette; Oppermann, Sina; Milde, Till; Witt, Olaf; Oehme, Ina Share Save
Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification Keck, Michaela-Kristina; Sill, Martin; Wittmann, Andrea; Joshi, Piyush; Stichel, Damian; Beck, Pengbo; Okonechnikow, Konstantin; Sievers, Philipp; Wefers, Annika K.; Roncaroli, Federico; Avula, Shivaram; McCabe, Martin G.; Hayden, James T.; Wesseling, Pieter; Ora, Ingrid; Nister, Monica; Kranendonk, Mariette E. G.; Tops, Bastiaan B. J.; Zapotocky, Michal; Zamecnik, Josef; Vasiljevic, Alexandre; Fenouil, Tanguy; Meyronet, David; von Hoff, Katja; Schuller, Ulrich; Loiseau, Hugues; Figarella-Branger, Dominique; Kramm, Christof M.; Sturm, Dominik; Scheie, David; Rauramaa, Tuomas; Pesola, Jouni; Gojo, Johannes; Haberler, Christine; Brandner, Sebastian; Jacques, Tom; Oates, Alexandra Sexton; Saffery, Richard; Koscielniak, Ewa; Baker, Suzanne J.; Yip, Stephen; Snuderl, Matija; Din, Nasir Ud; Samuel, David; Schramm, Kathrin; Blattner-Johnson, Mirjam; Selt, Florian; Ecker, Jonas; Milde, Till; von Deimling, Andreas; Korshunov, Andrey; Perry, Arie; Pfister, Stefan M.; Sahm, Felix; Solomon, David A.; Jones, David T. W. Share Save
The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets van Tilburg, Cornelis M.; Pfaff, Elke; Pajtler, Kristian W.; Langenberg, Karin P. S.; Fiesel, Petra; Jones, Barbara C.; Balasubramanian, Gnana Prakash; Stark, Sebastian; Johann, Pascal D.; Blattner-Johnson, Mirjam; Schramm, Kathrin; Dikow, Nicola; Hirsch, Steffen; Sutter, Christian; Grund, Kerstin; von Stackelberg, Arend; Kulozik, Andreas E.; Lissat, Andrej; Borkhardt, Arndt; Meisel, Roland; Reinhardt, Dirk; Klusmann, Jan-Henning; Fleischhack, Gudrun; Tippelt, Stephan; von Schweinitz, Dietrich; Schmid, Irene; Kramm, Christof M.; von Bueren, Andre O.; Calaminus, Gabriele; Vorwerk, Peter; Graf, Norbert; Westermann, Frank; Fischer, Matthias; Eggert, Angelika; Burkhardt, Birgit; Woessmann, Wilhelm; Nathrath, Michaela; Hecker-Nolting, Stefanie; Fruehwald, Michael C.; Schneider, Dominik T.; Brecht, Ines B.; Ketteler, Petra; Fulda, Simone; Koscielniak, Ewa; Meister, Michael T.; Scheer, Monika; Hettmer, Simone; Schwab, Matthias; Tremmel, Roman; Ora, Ingrid; Hutter, Caroline; Gerber, Nicolas U.; Lohi, Olli; Kazanowska, Bernarda; Kattamis, Antonis; Filippidou, Maria; Goemans, Bianca; Zwaan, C. Michel; Milde, Till; Jaeger, Natalie; Wolf, Stephan; Reuss, David; Sahm, Felix; von Deimling, Andreas; Dirksen, Uta; Freitag, Angelika; Witt, Ruth; Lichter, Peter; Kopp-Schneider, Annette; Jones, David T. W.; Molenaar, Jan J.; Capper, David; Pfister, Stefan M.; Witt, Olaf Share Save
Cerebrospinal Fluid Penetration and Combination Therapy of Entrectinib for Disseminated ROS1/NTRK-Fusion Positive Pediatric High-Grade Glioma Mayr, Lisa; Guntner, Armin S.; Madlener, Sibylle; Schmook, Maria T.; Peyrl, Andreas; Azizi, Amedeo A.; Dieckmann, Karin; Reisinger, Dominik; Stepien, Natalia M.; Schramm, Kathrin; Laemmerer, Anna; Jones, David T. W.; Ecker, Jonas; Sahm, Felix; Milde, Till; Pajtler, Kristian W.; Blattner-Johnson, Mirjam; Strbac, Miroslav; Dorfer, Christian; Czech, Thomas; Kirchhofer, Dominik; Gabler, Lisa; Berger, Walter; Haberler, Christine; Mullauer, Leonhard; Buchberger, Wolfgang; Slavc, Irene; Lotsch-Gojo, Daniela; Gojo, Johannes Share Save
DECIPHER pooled shRNA library screen identifies PP2A and FGFR signaling as potential therapeutic targets for diffuse intrinsic pontine gliomas Schramm, Kathrin; Iskar, Murat; Statz, Britta; Jaeger, Natalie; Haag, Daniel; Slabicki, Mikolaj; Pfister, Stefan M.; Zapatka, Marc; Gronych, Jan; Jones, David T. W.; Lichter, Peter Share Save
Somatic CRISPR/Cas9-mediated tumor suppressor disruption enables versatile brain tumor modeling Zuckermann, Marc; Hovestadt, Volker; Knobbe-Thomsen, Christiane B.; Zapatka, Marc; Northcott, Paul A.; Schramm, Kathrin; Belic, Jelena; Jones, David T. W.; Tschida, Barbara; Moriarity, Branden; Largaespada, David; Roussel, Martine F.; Korshunov, Andrey; Reifenberger, Guido; Pfister, Stefan M.; Lichter, Peter; Kawauchi, Daisuke; Gronych, Jan Share Save
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