Not logged inChromosome 3 copy number loss alone drives tumor evolution to aggressive disease in uveal melanoma
Srinivasan, Sanjana; Rose, Johnathon; Minelli, Rosalba; Terranova, Christopher; Shah, Parth; Daniele, Joseph R.; Peoples, Michael; He, Meng; Liu, Chiu-Yi; Gay, Jason; Soeung, Melinda; Soni, Sanjay; Wang, Fangyang; Bristow, Christopher; Wani, Khalida; Perelli, Luigi; Loza, Dmitry; Feng, Ningping; Tarabichi, Maxime; Van Loo, Peter; Futreal, Andrew; Woodman, Scott; Lazar, Alexander; Vellano, Christopher P.; Marszalek, Joseph; Draetta, Giulio F.; Heffernan, Timothy; Carugo, Alessandro; Genovese, Giannicola; Giuliani, Virginia .png)
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SaveChromosome 3 dosage-loss informs on the unique biology underlying ultra high-risk uveal melanomaRose, Johnathon Lynn; Srinivasan, Sanjana; He, Meng; Minelli, Rosalba; Liu, Chiu-Yi; Terranova, Christopher; Gay, Jason; Daniele, Joseph R.; Dmitriy, Loza; Peoples, Michael; Soeung, Melinda; Ramamoorthy, Vandhana; Shah, Parth; Soni, Sanjay; Bristow, Christopher; Wang, Fangyang; Lopez, Anastasia; Deckard, Charles; Meyers, Brooke; Perelli, Luigi; Wani, Khalida; Feng, Ningping; Vellano, Christopher P.; Marszalek, Joe; Lazar, Alexander J.; Futreal, Andrew; Draetta, Giulio F.; Woodman, Scott E.; Heffernan, Timothy; Genovese, Giannicola; Carugo, Alessandro; Giuliani, Virginia Share Save Advanced preclinical modeling reveals unique monosomy 3 associated biology in late-stage uveal melanomaRose, Johnathon L.; Srinivasan, Sanjana; He, Meng; Minelli, Rosalba; Liu, Chiu-Yi; Gay, Jason; Daniele, Joseph R.; Peoples, Michael; Soeung, Melinda; Ramamoorthy, Vandhana; Lopez, Anastasia; Deckard, Charles; Meyers, Brooke; Del Poggetto, Edoardo; Zamler, Daniel; Huang, Justin; Perelli, Luigi; Wani, Khalida; Bristow, Christopher; Feng, Ningping; Vellano, Christopher P.; Marszalek, Joe; Lazar, Alexander J.; Futreal, Andrew; Draetta, Giulio F.; Woodman, Scott E.; Heffernan, Timothy; Genovese, Giannicola; Carugo, Alessandro; Giuliani, Virginia Share Save Deploying spatial transcriptomics to inform intratumoral heterogeneity in late-stage uveal melanoma leveraging advanced preclinical modeling and clinical samplesSrinivasan, Sanjana; Rose, Johnathon; Daniele, Joseph R.; Peoples, Michael; He, Meng; Minelli, Rosalba; Liu, Chiu-Yi; Gay, Jason; Soeung, Melinda; Wani, Khalida; Perelli, Luigi; Loza, Dmitriy; Feng, Ningping; Vellano, Christopher P.; Marszalek, Joseph; Draetta, Giulio F.; Futreal, P. Andrew; Woodman, Scott E.; Lazar, Alexander J.; Heffernan, Timothy; Carugo, Alessandro; Genovese, Giannicola; Giuliani, Virginia Share Save Inhibition of protein arginine methylation alters RNA metabolism and DNA damage response providing a new therapeutic strategy in pancreatic ductal adenocarcinomaGiuliani, Virginia; Carugo, Alessandro; Miller, Meredith; Sanz, Lionel; Liu, Chiu-Yi; Bristow, Christopher A.; Suzuki, Erika; Class, Caleb A.; Hartono, Stella R.; Gao, Guang; Feng, Ningping; Gay, Jason P.; Vangamudi, Bhavatarini; Marszalek, Joseph R.; Kovacs, Jeffrey; Di Francesco, Maria Emilia; Chedin, Frederic; Jones, Philip; Draetta, Giulio; Heffernan, Timothy Share Save Identification of protein arginine methyltransferase 1 as novel epigenetic vulnerability in KRAS/p53 mutant PDAC primary patient modelsGiuliani, Virginia; Vangamudi, Bhavatarini; Suzuki, Erika; Miller, Meredith; Liu, Chiu-Yi; Carugo, Alessandro; Bristow, Christopher; Gao, Guang; Han, Jing; Sun, Yuting; Feng, Ningping; Chang, Edward; Marszalek, Joseph; Kovacs, Jeffrey; Di Francesco, Maria Emilia; Toniatti, Carlo; Heffernan, Timothy; Jones, Philip; Draetta, Giulio Share Save 
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