Not logged inSingle-cell RNA-sequencing of PBMCs from SAVI patients reveals disease-associated monocytes with elevated integrated stress response
de Cevins, Camille; Delage, Laure; Batignes, Maxime; Riller, Quentin; Luka, Marine; Remaury, Anne; Sorin, Boris; Fali, Tinhinane; Masson, Cecile; Hoareau, Benedicte; Meunier, Catherine; Parisot, Melanie; Zarhrate, Mohammed; Perot, Brieuc P.; Garcia-Paredes, Victor; Carbone, Francesco; Galliot, Lou; Nal, Beatrice; Pierre, Philippe; Canard, Luc; Boussard, Charlotte; Crickx, Etienne; Guillemot, Jean-Claude; Bader-Meunier, Brigitte; Belot, Alexandre; Quartier, Pierre; Fremond, Marie-Louise; Neven, Benedicte; Boldina, Galina; Auge, Franck; Alain, Fischer; Didier, Michel; Rieux-Laucat, Frederic; Menager, Mickaoel M.
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SaveTEAD Inhibitors Sensitize KRASG12C Inhibitors via Dual Cell Cycle Arrest in KRASG12C-Mutant NSCLC
Tammaccaro, Salvina Laura; Prigent, Philippe; Le Bail, Jean-Christophe; Dos-Santos, Odette; Dassencourt, Laurent; Eskandar, Myriam; Buzy, Armelle; Venier, Olivier; Guillemot, Jean-Claude; Veeranagouda, Yaligara; Didier, Michel; Spanakis, Emmanuel; Kanno, Tokuwa; Cesaroni, Matteo; Mathieu, Stephane; Canard, Luc; Casse, Alhassan; Windenberger, Fanny; Calvet, Loreley; Noblet, Laurence; Sidhu, Sukhvinder; Debussche, Laurent; Moll, Jurgen; Valtingojer, Iris
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SaveNotch activation shifts the fate decision of senescent progenitors toward myofibrogenesis in human adipose tissue
Boulet, Nathalie; Briot, Anais; Jargaud, Valentin; Esteve, David; Remaury, Anne; Belles, Chloe; Viana, Penelope; Fontaine, Jessica; Murphy, Lucie; Deon, Catherine; Guillemot, Marie; Pech, Catherine; Veeranagouda, Yaligara; Didier, Michel; Decaunes, Pauline; Mouisel, Etienne; Carpene, Christian; Iacovoni, Jason S.; Zakaroff-Girard, Alexia; Grolleau, Jean-Louis; Galitzky, Jean; Ledoux, Severine; Guillemot, Jean-Claude; Bouloumie, Anne
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SaveA Versatile Class of 1,4,4-Trisubstituted Piperidines Block Coronavirus Replication In Vitro
De Castro, Sonia; Stevaert, Annelies; Maldonado, Miguel; Delpal, Adrien; Vandeput, Julie; Van Loy, Benjamin; Eydoux, Cecilia; Guillemot, Jean-Claude; Decroly, Etienne; Gago, Federico; Canard, Bruno; Camarasa, Maria-Jose; Velazquez, Sonsoles; Naesens, Lieve
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SaveSynthesis, Structure-Activity Relationships, and Antiviral Profiling of 1-Heteroaryl-2-Alkoxyphenyl Analogs as Inhibitors of SARS-CoV-2 Replication
Bardiot, Dorothee; Vangeel, Laura; Koukni, Mohamed; Arzel, Philippe; Zwaagstra, Marleen; Lyoo, Heyrhyoung; Wanningen, Patrick; Ahmad, Shamshad; Zhang, Linlin; Sun, Xinyuanyuan; Delpal, Adrien; Eydoux, Cecilia; Guillemot, Jean-Claude; Lescrinier, Eveline; Klaassen, Hugo; Leyssen, Pieter; Jochmans, Dirk; Castermans, Karolien; Hilgenfeld, Rolf; Robinson, Colin; Decroly, Etienne; Canard, Bruno; Snijder, Eric J.; van Hemert, Martijn J.; van Kuppeveld, Frank; Chaltin, Patrick; Neyts, Johan; De Jonghe, Steven; Marchand, Arnaud
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SaveA dual mechanism of action of AT-527 against SARS-CoV-2 polymerase
Shannon, Ashleigh; Fattorini, Veronique; Sama, Bhawna; Selisko, Barbara; Feracci, Mikael; Falcou, Camille; Gauffre, Pierre; El Kazzi, Priscila; Delpal, Adrien; Decroly, Etienne; Alvarez, Karine; Eydoux, Cecilia; Guillemot, Jean-Claude; Moussa, Adel; Good, Steven S.; La Colla, Paolo; Lin, Kai; Sommadossi, Jean-Pierre; Zhu, Yingxiao; Yan, Xiaodong; Shi, Hui; Ferron, Francois; Canard, Bruno
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SaveObesity of mice lacking VAP-1/SSAO byAoc3gene deletion is reproduced in mice expressing a mutated vascular adhesion protein-1 (VAP-1) devoid of amine oxidase activity
Jargaud, Valentin; Bour, Sandy; Terce, Francois; Collet, Xavier; Valet, Philippe; Bouloumie, Anne; Guillemot, Jean-Claude; Mauriege, Pascale; Jalkanen, Sirpa; Stolen, Craig; Salmi, Marko; Smith, David J.; Carpene, Christian
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SaveA 3D Human Liver Model of Nonalcoholic Steatohepatitis
Duriez, Marion; Jacquet, Agnes; Hoet, Lucile; Roche, Sandrine; Bock, Marie-Dominique; Rocher, Corinne; Haussy, Gilles; Vige, Xavier; Bocskei, Zsolt; Slavnic, Tamara; Martin, Valerie; Guillemot, Jean-Claude; Didier, Michel; Kannt, Aimo; Orsini, Cecile; Mikol, Vincent; Le Fevre, Anne-Celine
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SaveIncretin combination therapy for the treatment of non-alcoholic steatohepatitis
Kannt, Aimo; Madsen, Andreas Nygaard; Kammermeier, Claire; Elvert, Ralf; Kloeckener, Tim; Bossart, Martin; Haack, Torsten; Evers, Andreas; Lorenz, Katrin; Hennerici, Wolfgang; Rocher, Corinne; Bocskei, Zsolt; Guillemot, Jean-Claude; Mikol, Vincent; Pattou, Francois; Staels, Bart; Wagner, Michael
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SaveA Human Stem Cell Model of Fabry Disease Implicates LIMP-2 Accumulation in Cardiomyocyte Pathology
Birket, Matthew J.; Raibaud, Sophie; Lettieri, Miriam; Adamson, Antony D.; Letang, Valerie; Cervello, Pauline; Redon, Nicolas; Ret, Gwenaelle; Viale, Sandra; Wang, Bing; Biton, Bruno; Guillemot, Jean-Claude; Mikol, Vincent; Leonard, John P.; Hanley, Neil A.; Orsini, Cecile; Itier, Jean-Michel
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SaveLobular architecture of human adipose tissue defines the niche and fate of progenitor cells
Esteve, D.; Boulet, N.; Belles, C.; Zakaroff-Girard, A.; Decaunes, P.; Briot, A.; Veeranagouda, Y.; Didier, M.; Remaury, A.; Guillemot, J. C.; Ledoux, S.; Dani, C.; Bouloumie, A.; Galitzky, J.
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SaveAntiviral Compounds from Codiaeum peltatum Targeted by a Multi-informative Molecular Networks Approach
Olivon, Florent; Remy, Simon; Grelier, Gwendal; Apel, Cecile; Eydoux, Cecilia; Guillemott, Jean-Claude; Neyts, Johan; Delang, Leen; Touboul, David; Roussi, Fanny; Litaudon, Marc
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SaveType 2/Th2-driven inflammation impairs olfactory sensory neurogenesis in mouse chronic rhinosinusitis model
Rouyar, Angela; Classe, Marion; Gorski, Raphael; Bock, Marie-Dominique; Le-Guern, Joelle; Roche, Sandrine; Fourgous, Valerie; Remaury, Anne; Paul, Pascal; Ponsolles, Clara; Francon, Dominique; Rocheteau-Beaujouan, Laurence; Clement, Margerie; Haddad, El-Bdaoui; Guillemot, Jean-Claude; Didier, Michel; Biton, Bruno; Orsini, Cecile; Mikol, Vincent; Leonetti, Maud
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SaveHijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors
Halby, Ludovic; Marechal, Nils; Pechalrieu, Dany; Cura, Vincent; Franchini, Don-Marc; Faux, Celine; Alby, Frederic; Troffer-Charlier, Nathalie; Kudithipudi, Srikanth; Jeltsch, Albert; Aouadi, Wahiba; Decroly, Etienne; Guillemot, Jean-Claude; Page, Patrick; Ferroud, Clotilde; Bonnefond, Luc; Guianvarc'h, Dominique; Cavarelli, Jean; Arimondo, Paola B.
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SaveNF-L in cerebrospinal fluid and serum is a biomarker of neuronal damage in an inducible mouse model of neurodegeneration
Brureau, Anthony; Blanchard-Bregeon, Veronique; Pech, Catherine; Hamon, Stephanie; Chaillou, Pascal; Guillemot, Jean-Claude; Barneoud, Pascal; Bertrand, Philippe; Pradier, Laurent; Rooney, Thomas; Schussler, Nathalie
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SaveCD36 Is a Marker of Human Adipocyte Progenitors with Pronounced Adipogenic and Triglyceride Accumulation Potential
Gao, Hui; Volat, Fanny; Sandhow, Lakshmi; Galitzky, Jean; Thuy Nguyen; Esteve, David; Astrom, Gaby; Mejhert, Niklas; Ledoux, Severine; Thalamas, Claire; Arner, Peter; Guillemot, Jean-Claude; Qian, Hong; Ryden, Mikal; Bouloumie, Anne
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