Not logged in The Lysine Demethylase KDM4C Is an Oncogenic Driver and Regulates ERK Activity in KRAS-Mutant Pancreatic Ductal Adenocarcinoma Shaheen, Menna-t-Allah; Dhebat, Sarah; Rajapakshe, Kimal I.; Ghosh, Bidyut; Chellakkan Selvanesan, Benson; Ansari, Shariq S.; Haymaker, Cara L.; Sadeghian, Dorsay; Wang, Huamin; Li, Ching-Fei; Ying, Haoqiang; Maitra, Anirban Share Save
Organ-specific diversity of tumor immune microenvironment in metastatic pancreatic cancer Min, Jimin; Branchi, Vittorio; Rajapakshe, Kimal I.; Narayanan, Nisha; Pei, Guangsheng; Wang, Linghua; Grem, Jean L.; Caffrey, Thomas C.; Grandgenett, Paul M.; Hollingsworth, Michael A.; Guerrero, Paola A.; Maitra, Anirban Share Save
Disruption of sulfatide metabolism by targeting UGT8 is an actionable metabolic vulnerability for pancreatic cancer early interception Ballaro, Riccardo; Chen, Yihui; Thege, Fredrik I.; Dou, Rongzhang; Min, Jimin; Yip-Schneider, Michele; Zhang, Jianjun; Wu, Ranran; Irajizad, Ehsan; Makino, Yuki; Rajapakshe, Kimal I.; Hurd, Mark W.; Leon-Letelier, Ricardo A.; Ostrin, Edwin; Vykoukal, Jody; Dennison, Jennifer B.; Do, Kim-Anh; Hanash, Samir; Wolff, Robert A.; Guerrero, Paola A.; Kim, Michael P.; Schmidt, C. Max; Maitra, Anirban; Fahrmann, Johannes F. Share Save
A comprehensive spatial atlas of neoadjuvant chemoradiation therapy in resected pancreatic cancer identifies cellular & microenvironmental determinants of persister populations Bernard, Vincent; Jacobson, Galia; Rajapakshe, Kimal; Min, Jimin; Pei, Guangsheng; Lin, Daniel; Suresh, Ayush; Jiang, Dadi; Tzeng, Ching-Wei; Bhutani, Manoop S.; Wang, Linghua; Guerrero, Paola A.; Ludmir, Ethan B.; Koong, Albert C.; Maitra, Anirban; Taniguchi, Cullen M.; Koay, Eugene J. Share Save
Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer Dilly, Julien; Hoffman, Megan T.; Abbassi, Laleh; Li, Ziyue; Paradiso, Francesca; Parent, Brendan D.; Hennessey, Connor J.; Jordan, Alexander C.; Morgado, Micaela; Dasgupta, Shatavisha; Uribe, Giselle A.; Yang, Annan; Kapner, Kevin S.; Hambitzer, Felix P.; Qiang, Li; Feng, Hanrong; Geisberg, Jacob; Wang, Junning; Evans, Kyle E.; Lyu, Hengyu; Schalck, Aislyn; Feng, Ningping; Lopez, Anastasia M.; Bristow, Christopher A.; Kim, Michael P.; Rajapakshe, Kimal I.; Bahrambeigi, Vahid; Roth, Jennifer A.; Garg, Kavita; Guerrero, Paola A.; Stanger, Ben Z.; Cristea, Simona; Lowe, Scott W.; Baslan, Timour; Van Allen, Eliezer M.; Mancias, Joseph D.; Chan, Emily; Anderson, Abraham; Katlinskaya, Yuliya V.; Shalek, Alex K.; Hong, David S.; Pant, Shubham; Hallin, Jill; Anderes, Kenna; Olson, Peter; Heffernan, Timothy P.; Chugh, Seema; Christensen, James G.; Maitra, Anirban; Wolpin, Brian M.; Raghavan, Srivatsan; Nowak, Jonathan A.; Winter, Peter S.; Dougan, Stephanie K.; Aguirre, Andrew J. Share Save
Integrated spatial transcriptomics and lipidomics analyses of intraductal papillary mucinous neoplasm identifies enrichment of long chain sulfatide as an early metabolic alteration Chen, Yihui; Sans, Marta; Thege, Fredrik; Dou, Rongzhang; Min, Jimin; Yip-Schneider, Michele; Zhang, Jianjun; Wu, Ranran; Irajizad, Ehsan; Makino, Yuki; Rajapakshe, Kimal; Hurd, Mark; Leon-Letelier, Ricardo; Vykoukal, Jody; Dennison, Jennifer; Do, Kim-Anh; Wolff, Robert; Guerrero, Paola; Kim, Michael; Schmidt, Max; Maitra, Anirban; Hanash, Samir; Fahrmann, Johannes Share Save
Transcriptomic Profiling of Plasma Extracellular Vesicles Enables Reliable Annotation of the Cancer-Specific Transcriptome and Molecular Subtype Bahrambeigi, Vahid; Lee, Jaewon J.; Branchi, Vittorio; Rajapakshe, Kimal I.; Xu, Zhichao; Kui, Naishu; Henry, Jason T.; Kun, Wang; Stephens, Bret M.; Dhebat, Sarah; Hurd, Mark W.; Sun, Ryan; Yang, Peng; Ruppin, Eytan; Wang, Wenyi; Kopetz, Scott; Maitra, Anirban; Guerrero, Paola A. Share Save
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Mutant GNAS drives glycolytic dependency in intraductal papillary mucinous neoplasms of the pancreas Makino, Yuki; Rajapakshe, Kimal; Yee, Nathaniel; Siemann, Megan; Min, Jimin; Selvanesan, Benson Chellakkan; Thege, Fredrik; Sagara, Akiko; Dutta, Prasanta; Bhattacharya, Pratip; Dede, Merve; Hart, Traver; Maitra, Anirban Share Save
Spatial Transcriptomics of Intraductal Papillary Mucinous Neoplasms of the Pancreas Identifies NKX6-2 as a Driver of Gastric Differentiation and Indolent Biological Potential Sans, Marta; Makino, Yuki; Min, Jimin; Rajapakshe, Kimal I.; Yip-Schneider, Michele; Schmidt, C. Max; Hurd, Mark W.; Burks, Jared K.; Gomez, Javier A.; Thege, Fredrik I.; Fahrmann, Johannes F.; Wolff, Robert A.; Kim, Michael P.; Guerrero, Paola A.; Maitra, Anirban Share Save
Histopathologic and transcriptomic phenotypes of a conditional RANKL transgenic mouse thymus Szwarc, Maria M.; Hai, Lan; Maurya, Vineet K.; Rajapakshe, Kimal; Perera, Dimuthu; Ittmann, Michael M.; Mo, Qianxing; Lin, Yong; Bettini, Matthew L.; Coarfa, Cristian; Lydon, John P. Share Save
LncRNA PVT-1 promotes osteosarcoma cancer stem-like properties through direct interaction with TRIM28 and TSC2 ubiquitination Tsang, Susan, V; Rainusso, Nino; Liu, Meng; Nomura, Motonari; Patel, Tajhal D.; Nakahata, Kengo; Kim, Ha Ram; Huang, Shixia; Rajapakshe, Kimal; Coarfa, Cristian; Man, Tsz-Kwong; Rao, Pulivarthi H.; Yustein, Jason T. Share Save
Calcium/calmodulin-dependent protein kinase kinase 2 regulates hepatic fuel metabolism Stork, Brittany A.; Dean, Adam; Ortiz, Andrea R.; Saha, Pradip; Putluri, Nagireddy; Planas-Silva, Maricarmen D.; Mahmud, Iqbal; Rajapakshe, Kimal; Coarfa, Cristian; Knapp, Stefan; Lorenzi, Philip L.; Kemp, Bruce E.; Turk, Benjamin E.; Scott, John W.; Means, Anthony R.; York, Brian Share Save
miR-181a Promotes Multiple Protumorigenic Functions by Targeting TGFβR3 Chitsazzadeh, Vida; Nguyen, Tran N.; Pulido, Alvaro de Mingo; Bittencourt, Bruna B.; Du, Lili; Adelmann, Charles H.; Rivera, Ivannie Ortiz; Nguyen, Kimberly A.; Guerra, Leah D.; Davis, Andrew; Napoli, Marco; Ma, Wencai; Davis, Richard Eric; Rajapakshe, Kimal; Coarfa, Cristian; Flores, Elsa R.; Tsai, Kenneth Y. Share Save
MAB21L4 Deficiency Drives Squamous Cell Carcinoma via Activation of RET Srivastava, Ankit; Tommasi, Cristina; Sessions, Dane; Mah, Angela; Bencomo, Tomas; Garcia, Jasmine M.; Jiang, Tiffany; Lee, Michael; Shen, Joseph Y.; Seow, Lek Wei; Nguyen, Audrey; Rajapakshe, Kimal; Coarfa, Cristian; Tsai, Kenneth Y.; Lopez-Pajares, Vanessa; Lee, Carolyn S. Share Save
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Loss of Rnf43 Accelerates Kras-Mediated Neoplasia and Remodels the Tumor Immune Microenvironment in Pancreatic Adenocarcinoma Hosein, Abdel Nasser; Dangol, Gita; Okumura, Takashi; Roszik, Jason; Rajapakshe, Kimal; Siemann, Megan; Zaid, Mohamed; Ghosh, Bidyut; Monberg, Maria; Guerrero, Paola A.; Singhi, Aatur; Haymaker, Cara L.; Clevers, Hans; Abou-Elkacem, Lotfi; Woermann, Sonja M.; Maitra, Anirban Share Save
Author Correction: ΔNp63 regulates a common landscape of enhancer associated genes in non-small cell lung cancer (vol 13, 614, 2022) Napoli, Marco; Wu, Sarah J.; Gore, Bethanie L.; Abbas, Hussein A.; Lee, Kyubum; Checker, Rahul; Dhar, Shilpa; Rajapakshe, Kimal; Tan, Aik Choon; Lee, Min Gyu; Coarfa, Cristian; Flores, Elsa R. Share Save
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