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Myeloperoxidase aggravates thoracic aortic aneurysm formation in Marfan disease Mehrkens, Dennis; Dohr, Johannes; Nettersheim, Felix Sebastian; Ballmann, Felix; Bastigkeit, Jil; Bruckner, Alexander; Geissen, Simon; De Vore, Lauren; Fitsch, Cedric; Diekmann, Chris; De La Fuente-alonso, Andrea; Schelemei, Patrik; Picard, Felix Ruben; Kochen, Malte; Arkenberg, Per; Rappenecker, Anna; Ahdab, Maysam; Nemade, Harshal; Narayan, Suchitra; Braumann, Simon; Kreuzberg, Wiebke; Hof, Alexander; Guthoff, Henning; Mensah, Benedicta Quaye; Lechner, Sebastian; Guala, Andrea; Evangelista, Artur; Teixido-Tura, Gisela; Nistal, J. Francisco; Campanero, Miguel R.; Kaemmerer, Harald; Wolf, Zsuzsanna; Holdenrieder, Stefan; Groenink, Maarten; Van Andel, Mitzi; Mieremet, Arnout; Pfeiler, Susanne; Gerdes, Norbert; Flogel, Ulrich; Zimmermann, Laura-Maria; Sengle, Gerhard; Eich, Marie-Lisa; Schomig-Markiefka, Birgid; Adam, Matti; Fleischmann, Bernd K.; Wenzel, Daniela; Redondo, Juan Miguel; De Waard, Vivian; Klinke, Anna; Baldus, Stephan; Mollenhauer, Martin; Winkels, Holger Share Save
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Prodomain processing controls BMP-10 bioactivity and targeting to fibrillin-1 in latent conformation Spanou, Chara E. S.; Yang, Chengeng; Godwin, Alan R. F.; Morosky, Stefanie; Anbalagan, Arulselvi; Luetke, Steffen; Morgelin, Matthias; Marcous, Fady; Aziz, Ubair; Wohl, Alexander P.; Jabeen, Ishrat; Koch, Manuel; Jowitt, Thomas A.; Roman, Beth L.; Tarakanova, Anna; Baldock, Clair; Sengle, Gerhard Share Save
New insights into the structural role of EMILINs within the human skin microenvironment Schiavinato, Alvise; Marcous, Fady; Zuk, Alexandra V.; Keene, Douglas R.; Tufa, Sara F.; Mosquera, Laura M.; Zigrino, Paola; Mauch, Cornelia; Eckes, Beate; Francois, Katrien; De Backer, Julie; Hunzelmann, Nicolas; Moinzadeh, Pia; Krieg, Thomas; Callewaert, Bert; Sengle, Gerhard Share Save
Dipeptidyl Peptidase-4-Mediated Fibronectin Processing Evokes a Profibrotic Extracellular Matrix Zeyer, Karina A.; Bornert, Olivier; Nelea, Valentin; Bao, Xinyi; Leytens, Alexandre; Sharoyan, Svetlana; Sengle, Gerhard; Antonyan, Alvard; Bruckner-Tuderman, Leena; Dengjel, Jorn; Reinhardt, Dieter P.; Nystrom, Alexander Share Save
ADAMTS12 promotes fibrosis by restructuring extracellular matrix to enable activation of injury- responsive fibroblasts Hoeft, Konrad; Koch, Lars; Ziegler, Susanne; Zhang, Ling; Luetke, Steffen; Tanzer, Maria C.; Mohanta, Debashish; Schumacher, David; Schreibing, Felix; Long, Qingqing; Kim, Hyojin; Klinkhammer, Barbara M.; Schikarski, Carla; Maryam, Sidrah; Baens, Mathijs; Hermann, Juliane; Krieg, Sarah; Peisker, Fabian; De Laporte, Laura; Schaefer, Gideon J. L.; Menzel, Sylvia; Jankowski, Joachim; Humphreys, Benjamin D.; Wahida, Adam; Schneider, Rebekka K.; Versele, Matthias; Boor, Peter; Mann, Matthias; Sengle, Gerhard; Hayat, Sikander; Kramann, Rafael Share Save
Fibrillin microfibril structure identifies long-range effects of inherited pathogenic mutations affecting a key regulatory latent TGFβ-binding site (vol 30, pg 608, 2023) Godwin, Alan R. F.; Dajani, Rana; Zhang, Xinyang; Thomson, Jennifer; Holmes, David F.; Adamo, Christin S.; Sengle, Gerhard; Sherratt, Michael J.; Roseman, Alan M.; Baldock, Clair Share Save
Development Of A Phenotypic Screen With 56 Marfan Syndrome Patient-derived Fibroblasts Mieremet, Arnout; van Andel, Mitzi; Morcos, Yousef; Sengle, Gerhard; Reinhardt, Dieter; Mulder, Barbara; Zwinderman, Aeilko; Groenink, Maarten; Driessen, Antoine; Micha, Dimitra; de Waard, Vivian Share Save
Fibrillin microfibril structure identifies long-range effects of inherited pathogenic mutations affecting a key regulatory latent TGFβ-binding site Godwin, Alan R. F.; Dajani, Rana; Zhang, Xinyang; Thomson, Jennifer; Holmes, David F.; Adamo, Christin S.; Sengle, Gerhard; Sherratt, Michael J.; Roseman, Alan M.; Baldock, Clair Share Save
Targeting of bone morphogenetic protein complexes to heparin/heparan sulfate glycosaminoglycans in bioactive conformation Spanou, Chara E. S.; Wohl, Alexander P.; Doherr, Sandra; Correns, Annkatrin; Sonntag, Niklas; Luetke, Steffen; Morgelin, Matthias; Imhof, Thomas; Gebauer, Jan M.; Baumann, Ulrich; Grobe, Kay; Koch, Manuel; Sengle, Gerhard Share Save
EMILIN1 deficiency causes arterial tortuosity with osteopenia and connects impaired elastogenesis with defective collagen fibrillogenesis Adamo, Christin S.; Beyens, Aude; Schiavinato, Alvise; Keene, Douglas R.; Tufa, Sara F.; Morgelin, Matthias; Brinckmann, Jurgen; Sasaki, Takako; Niehoff, Anja; Dreiner, Maren; Pottie, Lore; Muino-Mosquera, Laura; Gulec, Elif Yilmaz; Gezdirici, Alper; Braghetta, Paola; Bonaldo, Paolo; Wagener, Raimund; Paulsson, Mats; Bornaun, Helen; De Rycke, Riet; De Bruyne, Michiel; Baeke, Femke; Devine, Walter P.; Gangaram, Balram; Tam, Allison; Balasubramanian, Meena; Ellard, Sian; Moore, Sandra; Symoens, Sofie; Shen, Joseph; Cole, Stacey; Schwarze, Ulrike; Holmes, Kathryn W.; Hayflick, Susan J.; Wiszniewski, Wojciech; Nampoothiri, Sheela; Davis, Elaine C.; Sakai, Lynn Y.; Sengle, Gerhard; Callewaert, Bert Share Save
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Sensitive asprosin detection in clinical samples reveals serum/saliva correlation and indicates cartilage as source for serum asprosin Morcos, Yousef A. T.; Luetke, Steffen; Tenbieg, Antje; Hanisch, Franz-Georg; Pryymachuk, Galyna; Piekarek, Nadin; Hoffmann, Thorben; Keller, Titus; Janoschek, Ruth; Niehoff, Anja; Zaucke, Frank; Doetsch, Joerg; Hucklenbruch-Rother, Eva; Sengle, Gerhard Share Save
Bi-allelic premature truncating variants in LTBP1 cause cutis laxa syndrome (vol 108, pg 1095, 2021) Pottie, Lore; Adamo, Christin S.; Beyens, Aude; Lutke, Steffen; Tapaneeyaphan, Piyanoot; De Clercq, Adelbert; Salmon, Phil L.; De Rycke, Riet; Gezdirici, Alper; Gulec, Elif Yilmaz; Khan, Naz; Urquhart, Jill E.; Newman, William G.; Metcalfe, Kay; Efthymiou, Stephanie; Maroofian, Reza; Anwar, Najwa; Maqbool, Shazia; Rahman, Fatima; Altweijri, Ikhlass; Alsaleh, Monerah; Abdullah, Sawsan Mohamed; Al-Owain, Mohammad; Hashem, Mais; Houlden, Henry; Alkuraya, Fowzan S.; Sips, Patrick; Sengle, Gerhard; Callewaert, Bert Share Save
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